Intoxication by Cyanide in Pregnant Sows: Prenatal and Postnatal Evaluation by André T. Gotardo, Isis M. Hueza, Helena Manzano, Viviane M. Maruo, Paulo C. Maiorka, Silvana L. Górniak

“…Cyanide is a ubiquitous chemical in the environment and has been associated with many intoxication episodes; however, little is known about its potentially toxic effects on development. The aim of this study was to evaluate the effects of maternal exposure to potassium cyanide (KCN) during pregnancy on both sows and their offspring. …”
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A review of bismuth‐based nanoparticles and their applications in radiosensitising and dose enhancement for cancer radiation therapy by Daryoush Shahbazi‐Gahrouei, Yazdan Choghazardi, Arezoo Kazemzadeh, Paria Naseri, Saghar Shahbazi‐Gahrouei

“…Recently, bismuth‐based nanoparticles (BiNPs) have become particularly popular in radiation therapy due to their high atomic numbers (Z), high X‐ray attenuation coefficient, low toxicity, and low cost. Moreover, it is easy to synthesise in a variety of sizes and shapes. …”
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Hypofractionated External-Beam Radiotherapy for Prostate Cancer by L. Chinsoo Cho, Robert Timmerman, Brian Kavanagh

“…The preliminary results from clinical studies indicate that abbreviated fractionation programs can result in successful treatment of localized prostate cancer without escalation of late toxicity.…”
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Stinging Nettles of Florida: Cnidoscolus by Wendy B. Zomlefer

“…Zomlefer, describes this perennial herb with stinging hairs, milky sap, and tuberous roots — its classification, description, similar species, and toxicity. Includes references. Published by the UF Herbarium, October 2008. …”
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Stinging Nettles of Florida: Cnidoscolus by Wendy B. Zomlefer

“…Zomlefer, describes this perennial herb with stinging hairs, milky sap, and tuberous roots — its classification, description, similar species, and toxicity. Includes references. Published by the UF Herbarium, October 2008. …”
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Integrating machine learning and structure-based approaches for repurposing potent tyrosine protein kinase Src inhibitors to treat inflammatory disorders by Muhammad Waleed Iqbal, Muhammad Shahab, Zakir ullah, Guojun Zheng, Irfan Anjum, Gamal A. Shazly, Atrsaw Asrat Mengistie, Xinxiao Sun, Qipeng Yuan

“…Molecular Mechanics/Generalized Born Surface Area (MMGBSA) analysis validated their binding affinities by providing comparably lower binding free energies for orlistat (− 33.4743 ± 3.8908), acarbose (− 19.5455 ± 5.4702), and afatinib (− 36.4944 ± 5.4929) than the control, dasatinib (− 13.7785 ± 5.8058). Finally, toxicity analysis revealed orlistat and acarbose as the possible safer therapeutics by eliminating afatinib as it showed significant toxicity concerns. …”
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Application of trichloroisocyanuric acid in controlling kiwifruit bacterial canker disease demonstrates its promising potential as an eco-friendly bactericide by Jianyou Gao, Jiewei Li, Cuixia Liu, Hongjuan Gong, Beibei Qi, Rongxiang Zhu, Liming Xia, Li Li, Shibiao Liu, Qiaosheng Jiang, Kaiyu Ye, Faming Wang

“…Abstract The growing concerns over food safety have intensified calls for alternatives to toxic pesticides in agriculture. Despite these concerns, the global agricultural industry remains heavily reliant on chemical pesticides to maintain crop yields. …”
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One-pot synthesis and characterization of a BSA-Cu2S/CuS quantum dots drug delivery system based on biuret’s reaction by Porfirio Estrada-Rojas, Juan Francisco Hernández-Paz, Claudia Alejandra Rodríguez-González, Mónica Elvira Mendoza-Duarte, Santos Adriana Martel-Estrada, Laura Elizabeth Valencia-Gómez, Héctor Camacho-Montes, Imelda Olivas-Armendáriz

“…Finally, MTT assays confirmed that the synthesized quantum dots are non-toxic, further supporting their potential for biomedical applications.…”
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Anti-Inflammatory and Healing Activity of the Hydroalcoholic Fruit Extract of Solanum diploconos (Mart.) Bohs by Larissa Benvenutti, Roberta Nunes, Ivonilce Venturi, Silvia Aparecida Ramos, Milena Fronza Broering, Fernanda Capitanio Goldoni, Sarah Eskelsen Pavan, Maria Verônica Dávila Pastor, Angela Malheiros, Nara Lins Meira Quintão, Elizabeth Soares Fernandes, José Roberto Santin

“…Additionally, the acute and subacute toxic and genotoxic effects of the extract were evaluated. …”
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Fish Scale-Derived Scaffolds for Culturing Human Corneal Endothelial Cells by Mohit Parekh, Bert Van den Bogerd, Nadia Zakaria, Diego Ponzin, Stefano Ferrari

“…Hoechst, ethidium homodimer, and calcein AM (HEC) staining was performed to determine viability and toxicity (n=6). The cell surface area was calculated based on calcein AM staining. …”
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iPSC-derived exosomes as amphotericin B carriers: a promising approach to combat cryptococcal meningitis by Jingyu Zhao, Jingyu Zhao, Wei Fang, Yangjie Gao, Jiquan Chen, Guizhen Wang, Julin Gu

“…The minimum inhibitory concentration (MIC) of iPSC-Exo/AmB and conventional AmB against Cryptococcus was determined.ResultsThe iPSC-Exo/AmB complex exhibited reduced cytotoxicity in vitro and decreased AmB-induced renal and hepatic toxicity in vivo. Its MIC against Cryptococcus was over eight times lower than conventional AmB, significantly reducing fungal burden in the mouse brain and lowering serum inflammatory factors.ConclusionThe iPSC-Exo/AmB complex is a promising therapeutic strategy that enhances AmB efficacy while reducing toxicity, offering new hope for treating CM and other refractory fungal infections of the central nervous system.…”
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In vivo scanning laser fundus and high-resolution OCT imaging of retinal ganglion cell injury in a non-human primate model with an activatable fluorescent-labeled TAT peptide probe... by Xudong Qiu, Seth T Gammon, Carol Rasmussen, Federica Pisaneschi, Charlene B Y Kim, James Ver Hoeve, Steven W Millward, Edward M Barnett, T Michael Nork, Paul L Kaufman, David Piwnica-Worms

“…No evidence of pan-retinal toxicity or loss of retino-cortical function was detected in any of the three NHPs tested. …”
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Comparison of new secondgeneration H1 receptor blockers with some molecules; a study involving DFT, molecular docking, ADMET, biological target and activity by Velid Unsal, Erkan Oner, Reşit Yıldız, Başak Doğru Mert

“…Vitamin C and Quercetin were found to be safer in terms of cardiac toxicity and mutagenic risks, while Desloratadine and Levocetirizine carried high risks of neurotoxicity and hematotoxicity, while CAPE was noted for its high enzyme inhibitory activities and low toxicity profiles, while the hERG blockade, DILI, and cytotoxicity values of other compounds pointed to various safety concerns. …”
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The Safety and Efficacy of the Repeated PRRT with [90Y]Y/[177Lu]Lu-DOTATATE in Patients with NET by Anna Zemczak, Paweł Gut, Dariusz Pawlak, Maciej Kołodziej, Leszek Królicki, Beata Kos-Kudła, Marek Ruchała, Grzegorz Kamiński, Jolanta Kunikowska

“…Myelodysplastic syndrome occurred in one patient (3.8%), and grade 4 renal toxicity was also detected in one patient (3.8%). No other cases of grade 3 or 4 bone marrow and renal toxicity were observed. …”
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Dysregulation of the Autophagy-Endolysosomal System in Amyotrophic Lateral Sclerosis and Related Motor Neuron Diseases by Asako Otomo, Lei Pan, Shinji Hadano

“…It is currently believed that a complex interplay of multiple toxicity pathways is implicated in disease onset and progression. …”
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Biological Evaluation of Garcinia kola Heckel by Abdulrahman Mahmoud Dogara, Saber W. Hamad, Harmand A. Hama, Sarwan W. Bradosty, Soran Kayfi, Sawsan S. Al-Rawi, Abubakar Abdullahi Lema

“…Antioxidant, antimicrobial, antidiabetic, antibacterial, medications, antiviral, traditional medicine, ethnopharmacology, toxicity, cytotoxic action, chemical composition, mineral elements, GCMS analysis, and any other related phrases were used as filters to find studies. …”
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Protective Effect of Thyme Extract on Albino Rats Exposed to Paraquat by Nazar M. Shareef Mahmood

“…Therefore, the current results indicate that, the herbicide PQ showed adverse effects through initiation of lipid peroxidation, while T.vulgaris extract produced a significant recovery in ameliorating some aspects of PQ toxicity. …”
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Susceptibility Evaluation of Fall Armyworm (Spodoptera frugiperda) Infesting Maize in Kenya against a Range of Insecticides by Savinda Njeri Gichere, Kakai Shem Khakame, Okoth Patrick

“…The current study illustrated the high toxicity of spinetoram, spinosad, lufenuron, and pyridaben to fall armyworm while indoxacarb, deltamethrin, lambda-cyhalothrin, imidacloprid, and abamectin exhibited relatively low toxicity to fall armyworm. …”
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Pharmacokinetic Study of Di-Phenyl-Di-(2,4-Difluobenzohydroxamato)Tin(IV): Novel Metal-Based Complex with Promising Antitumor Potential by Yunlan Li, Zhuyan Gao, Pu Guo, Qingshan Li

“…Di-phenyl-di-(2,4-difluobenzohydroxamato)tin(IV)(DPDFT), a new metal-based arylhydroxamate antitumor complex, showed high in vivo and in vitro antitumor activity with relative low toxicity, but no data was reported regarding its pharmacokinetics and dependent toxicity. …”
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Numerical research on the influence of ventilation velocity on fire smoke distribution in bifurcated roadway by Cui DING

“…When the ventilation velocity is 1-3 m/s, the workers in the sub-roadway are less susceptible to fire smoke and toxic gases, and when the ventilation velocity is 1.5-3 m/s, the workers in the main-roadway downstream are less susceptible to fire smoke and toxic gases…”
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