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1361
Liquid waste treatment containing Rhodamine B using emulsion liquid membrane from waste cooking oil
Published 2025-03-01“…WCO offers advantages as a non-toxic, non-flammable, and accessible solvent that reduces secondary pollution and costs. …”
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1362
DNA Vaccination: Using the Patient's Immune System to Overcome Cancer
Published 2010-01-01“…Optimization of standard treatment protocols consisting of the main columns of chemo- and radiotherapy followed or preceded by surgical intervention is often limited by toxic side effects and induction of concomitant malignancies and/or development of resistant mechanisms. …”
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1363
Natural products as part of triple negative breast cancer
Published 2025-01-01“…Immunotherapy causes a wide variety of toxic effects called immune-related adverse events (IRAEs). …”
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1364
Metabolic stability and its role in the discovery of new chemical entities
Published 2019-09-01“…Rapid biotransformation reduces exposure to the maternal compound and may lead to the generation of active, non-active or toxic metabolites. In contrast, high metabolic stability may promote interactions between drugs and lead to parent compound toxicity. …”
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1365
Properties of new polycationic bacteriochlorin photosensitizers: cytotoxicity and interaction with biofilms
Published 2024-09-01“…Now, we compared the toxicity of these PS to bacteria and human fibroblasts, under irradiation and in the dark. …”
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1366
Integrating MAPK pathway inhibition into standard-of-care therapy for pediatric low-grade glioma
Published 2025-02-01“…We have adopted mitigation strategies for their associated toxicities; skin toxicity, in particular, is now managed by prevention strategies and early dermatologic intervention. …”
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1367
A phase I/II study evaluating the feasibility and safety of delivering adjuvant hypofractionated radiotherapy in resected oral cavity cancers (HYPO-ART study)
Published 2024-06-01“…The primary end-point was the incidence of acute radiation-induced toxicities. Secondary endpoints were locoregional control and overall survival. …”
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1368
NLS-binding deficient Kapβ2 reduces neurotoxicity via selective interaction with C9orf72-ALS/FTD dipeptide repeats
Published 2025-01-01“…R-DPRs can cause toxicity by disrupting the natural phase behavior of RNA-binding proteins (RBPs). …”
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1369
Humanising nanotoxicology: replacement of animal-derived products in the application of integrated approaches to testing and assessment of nanomaterial inhalation hazard
Published 2025-02-01“…Further investigation is needed to support a shift toward more ethical toxicity testing that does not rely on animal-derived materials.…”
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1370
Graphene-metal sulfide composite based gas sensors for environmental sustainability: A review
Published 2024-01-01“…In this modern era, maintaining a sustainable environment is pivotal and hence, a detailed review on gas sensors for quantification of toxic environmental pollutants is critical. In this paper, an extensive review on advancements in gas sensors developed using graphene-metal sulfide composites is discussed. …”
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1371
Review of the environmental and health risks of hydraulic fracturing fluids
Published 2025-01-01“…The environmental and health hazards posed by HF fluid are concerning due to the high concentration of toxic chemicals, the limited data on toxicity, the high probability of spills, and the reported cases of aquifer contamination. …”
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1372
Efficacy of natural killer T and gammadelta T cells in mesothelin-targeted immunotherapy of pancreatic cancer
Published 2025-02-01“…Despite their promise, dose-limited toxicity (DLT) remains a challenge in clinical practice. …”
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1373
Comparative environmental impacts analysis of technologies for recovering critical metals from copper anode slime: Insights from LCA
Published 2025-01-01“…Six impact categories—climate change, freshwater ecotoxicity, marine ecotoxicity, terrestrial ecotoxicity, human toxicity (cancer), and human toxicity (non-cancer)—were assessed and compared across the four recycling technologies. …”
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1374
Glutathione reductase plays a role in the metabolism of methylmercury degradation in Rhodotorula mucilaginosa
Published 2025-02-01“…ABSTRACT Mercury pollution is a kind of heavy metal pollution with great harm and strong toxicity which exists worldwide. Some microorganisms can convert highly toxic methylmercury into inorganic mercury compounds with significantly reduced toxicity. …”
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1375
Metabolic conversion of phenol to polyhydroxyalkanoate (PHA) for addressing dual environmental challenges: A review
Published 2025-01-01“…A sustainable approach to microbial polyhydroxyalkanoate (PHA) production involves utilizing waste as a substrate, which can include toxic pollutants like phenol as a carbon feedstock. …”
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1376
Arbuscular mycorrhizal fungi mitigate cadmium stress in maize
Published 2025-01-01“…Recent studies have highlighted the potential of arbuscular mycorrhizal (AM) fungi to protect crops from various heavy metal stresses, including Cd toxicity. To elucidate the tolerance mechanisms of maize in response to Cd toxicity under AM symbiosis, this study used two maize genotypes with contrasting Cd tolerance: Zhengdan958 (Cd-tolerant) and Zhongke11 (Cd-sensitive). …”
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1377
Efficacy and Safety of Low-Dose Lenvatinib and Toripalimab in Patients With Recurrent Platinum-Resistant Ovarian Cancer: Study Protocol of a Multicenter, Open-Label, Single-Arm, Ph...
Published 2025-02-01“…PROC patients with multiple recurrences are unable to continue highly toxic treatment after prior multiple lines of systemic therapy. …”
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1378
Life cycle assessment of paper products based on recycled and virgin fiber
Published 2023-11-01“…The results of the impact assessment of global warming potential fossil, acidification, particulates, fossil abiotic depletion, and human toxicity-cancer for duplex board were 1,848.26 kilogram carbon dioxide equivalent, 8.12 kilogram-sulfur-dioxide-equivalent, 2.12 kilogram particulate matter 2.5-equivalent, 14,668.06 megajoule, and 0.0000017 comparative toxic unit, while for folding boxboard 2,651.25 kilogram carbon- dioxide-equivalent, 13.95 kilogram sulfur-dioxide-equivalent, 3.27 kilogram particulate matter 2.5-equivalent, 22,395.81 mega-joule, and 0.0000021 comparative toxic unit, respectively. …”
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1379
Tau-Reactive Endogenous Antibodies: Origin, Functionality, and Implications for the Pathophysiology of Alzheimer’s Disease
Published 2019-01-01“…In Alzheimer’s disease (AD), tau pathology manifested by the accumulation of intraneuronal tangles and soluble toxic oligomers emerges as a promising therapeutic target. …”
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1380
Sonication-Assisted Synthesis of β-Mercuric Sulfide Nanoparticles
Published 2012-12-01“…Continued development of synthesis methods is needed to expand approaches that produce uniform particles, while avoiding reagents of high toxicity and ecological impact. A solvent‐based approach was developed using mercuric chloride and elemental sulphur as the mercury and chalcogenide sources. …”
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