Relaxin inhibits 177Lu-EDTMP associated cell death in osteosarcoma cells through notch-1 pathway by Xu Junhua, Wan Song, Chen Wei, Zhang Yi, Ji Zhenzhong

“…We reported that RLXH2 significantly declined cellular toxicity and apoptosis associated with 177Lu-EDTMP in MG63 and Saos-2 cells through the notch-1 pathway.…”
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Optimizing Bioaugmentation for Pharmaceutical Stabilization of Sewage Sludge: A Study on Short-Term Composting Under Real Conditions by Gabriela Angeles-De Paz, Juan Cubero-Cardoso, Clementina Pozo, Concepción Calvo, Elisabet Aranda, Tatiana Robledo-Mahón

“…Their uncomplete removal and lack of monitoring during composting neglects their potentially toxic effects when used as a soil organic amendment. …”
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Risk Assessment of Trace Element Contamination in Drinking Water and Agricultural Soil: A Study in Selected Chronic Kidney Disease of Unknown Etiology (CKDu) Endemic Areas in Sri L... by W. P. R. T. Perera, M. D. N. R. Dayananda, D. M. U. C. Dissanayake, R. A. S. D. Rathnasekara, W. S. M. Botheju, J. A. Liyanage, S. K. Weragoda, K. A. M. Kularathne

“…Geoaccumulation indexes (Igeo) of soil reveal that paddy soil in CKDu endemic areas is being moderately polluted with toxic metals/metalloids such as As, Pb, Cu, Ni, Cr, Zn, and Cd. …”
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Protective effects of resveratrol and naringenin against nonylphenol-induced oxidative stress in rats by Haitham S. Elewa, Dawlat A. Salama, Mohamed S. Hikal, Mohamed F. Abd El hamid, Mohamed H. Eid, Fatma M. A. Khalil, Muayad S. Albadrani, Khaled Abdelaal, Ahmed I. El-Tokhy

“…This study was conducted to investigate the toxicity of NP and the mitigating effects of RES and NG on NP toxicity in rats. …”
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Ru(II) Complexes Bearing O, O-Chelated Ligands Induced Apoptosis in A549 Cells through the Mitochondrial Apoptotic Pathway by Jincan Chen, Jie Wang, Yuanyuan Deng, Tao Wang, Tifang Miao, Chengpeng Li, Xianhong Cai, Ying Liu, Justin Henri, Lanmei Chen

“…Notably, complex Ru-1 showed low toxicity to developing zebrafish embryos. The obtained results suggest that these new synthetic complexes have the potential to be developed as low-toxicity agents for lung cancer treatment.…”
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Bisphenol S impairs oocyte quality by inducing gut microbiota dysbiosis by Jiaming Zhang, Xiaoxia Yu, Weidong Li, Yunjing Jiang, Liangran Zhang, Shunxin Wang

“…These findings present a major advance in the understanding of bisphenol S toxicity to oocytes and also provide a preventive strategy.…”
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A Survey of Mycotoxin Contamination in Fermented Condiments and the Biological Methods for Its Reduction by WANG Lihui, FU Jinhui, LI Chaowei, ZHANG Li, XIA Xiaolong, LI Sitong, ZHANG Mengmei, CHEN Yinzhu, LIU Shuliang, HU Kaidi, ZHAO Ning, LI Qin, LI Jianlong

“…Microorganisms can convert mycotoxins into low-toxicity or non-toxic substances through the adsorption of cell walls or enzymatic catalysis, thus ensuring the safety of fermented condiments for consumption. …”
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Study on the pathogenesis of pathophysiological changes of burn systemic infection by Li Ao (Ngao), Huang Yuesheng, Yang Zongcheng

“…The present prospective study showed that incidence of systemic infection in severe burn patients was 30.9%. Toxic shock and multiple organ failure (MOF) developed in all patients with uncontrolled systemic infection. …”
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PPARα as a Transcriptional Regulator for Detoxification of Plant Diet-Derived Unfavorable Compounds by Bunichiro Ashibe, Yu Nakajima, Yuka Fukui, Kiyoto Motojima

“…Plants contain potentially toxic compounds for animals and animals have developed physiological strategies to detoxify the ingested toxins during evolution. …”
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UV Dose Governs UV-Polymerized Polyacrylamide Hydrogel Modulus by Saahil Sheth, Era Jain, Amin Karadaghy, Sana Syed, Hunter Stevenson, Silviya P. Zustiak

“…This method, while generally well accepted, has its drawbacks: long polymerization times, unstable and toxic reagents, and tedious preparation. Alternatively, PAA gels could be made by free radical polymerization (FRP) using ultraviolet (UV) photopolymerization, a method which is quicker, less tedious, and less toxic. …”
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A PROJECT MANAGEMENT GEOINFORMATICS UTILITY FOR HEALTH PROTECTION AND SANITARY DRAWINGS IN GREEN CONSTRUCTIONS - INFRASTRUCTURE WORKS by TILEMACHOS KOLIOPOULOS, SOKRATIS THEOCHARATOS, PANAGIOTIS KOULOUMPIS, CRINA RADU, ION CRISTEA

“…Reclamation works are examined in associated risks minimisation of toxic hazardous concentrations that could enter in water resources, food chain and agricultural resources. …”
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Multisystemic Side Effects of an Indispensable Old Drug: A Case Report of Chronic Lithium Use (A Patient with Multiple Side Effects of Lithium) by Levent Demirtas, Emin Murat Akbas, Husnu Degirmenci, Ali Gurel, Eren Duzgun

“…Health care professionals should keep in mind that lithium-related side effects might trigger or exacerbate each other. To avoid toxicity, close follow-up and clinical supervision are important for the early diagnosis and treatment of these side effects, due to the narrow therapeutic index and obscure clinical signs and symptoms of toxicity.…”
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Vers une prévention intégrée du risque chimique lié à l’exposition cutanée au bitume des travailleurs de la route. Élaboration d’une méthodologie dans le cadre de l’ergotoxicologie... by Nathalie Judon, Florence Hella, Pierrick Pasquereau, Alain Garrigou

“…This work is part of an initiative to prevent risks for asphalt workers of dermal exposure to toxic substances present in bitumen. An iterative method was developed, based on both an ergotoxicological approach and on the combining of observations of construction workers’ work activities with physical and physiological measures. …”
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Synthesis of Isatin Derivative on the Short Multiwalled Carbon Nanotubes and Their Effect on the MKN-45 and SW742 Cancer Cells by Hasan Tahermansouri, Farshid Chitgar

“…Cellular results showed high toxicity of Sh-MWCNT-Amide in all samples investigated.…”
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Artemisinin-Based Combination Therapy Depressed Mitosis and Induced Chromosome Aberration in Onion Root Cells by J. I. Raji, C. K. Onwuamah, P. G. C. Odeigah

“…The toxicity on the mitotic index varies with the duration of exposure and dose tested. …”
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Comparative Study of Protective Effect of Cimetidine and Verapamil on Paracetamol-Induced Hepatotoxicity in Mice by Lubna Danish, Riffat Siddiq, Sarwat Jahan, Mehwish Taneez, Manzoor Khan, Marva Sandhu

“…Cimetidine by inhibiting the cytochromal enzymes and reducing the production of the toxic metabolite can reduce the hepatotoxic potential while Verapamil can act as a hepatoprotective by maintaining calcium homeostasis. …”
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Salt stress and its eco-friendly management using biostimulants in grain legumes: a review by Narayan Singh, Vasudha Maurya, Kriti Gupta, Indu Sharma, Ashutosh Sharma, Rahul Kumar

“…Biostimulants successfully alleviate salt stress-induced toxicities in legumes, when introduced either alone or in combination with other macro- or microorganisms in the soil. …”
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Effect of Problem Based Learning Scenario on Knowledge of Third Class Students About Childhood Poisoning by Nazan Karaoğlu, Sevgi Pekcan, Burak Cem Soner, Muzaffer Şeker, Rahmi Örs

“…Number of correct answers increased significantly for knowledge about commonly used drugs in clinical practice like anti-depressants, calcium canal blockers, oral antidiabetics that were marked as non-toxic by the students although they are toxic (p<0.05). …”
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Potential of albumin dialysis at terminal liver failure in patients with chronic liver diseases by O. E. Nikiforova, Ye. N. Bessonova, O. M. Lesnyak, O. A. Stroganova

“…Among patients, receiving treatment with albumin dialysis the stage of hepatic encephalopathy at patients in the subgroup with cirrhosis of toxic (alcohol-induced) etiology significantly decreased (р&lt;0,01). …”
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Engineering a tumor-selective prodrug T-cell engager bispecific antibody for safer immunotherapy by Amelia C. McCue, Stephen J. Demarest, Karen J. Froning, Michael J. Hickey, Stephen Antonysamy, Brian Kuhlman

“…On-target, off-tumor toxicity can arise when the target antigen is also present on healthy cells. …”
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