Polycarbonate Microchip Containing CuBTC-Monopol Monolith for Solid-Phase Extraction of Dyes by Eman Alzahrani

“…Such features showed that fabricated CuBTC-monopol monolithic disk polycarbonate microchips have the potential of extracting toxic dyes that could be utilized for treating wastewater.…”
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The Role of the Enterohepatic Circulation of Bile Salts and Nuclear Hormone Receptors in the Regulation of Cholesterol Homeostasis: Bile Salts as Ligands for Nuclear Hormone Recept... by Richard N Redinger

“…FXR also targets sodium taurocholate cotransport peptide and bile salt export pump (protein) genes to limit bile salt uptake and enhance export, respectively, which prevents bile salt toxicity. Other nuclear hormone receptors such as pregnan X receptor, which share the obligate partner, retinoid X receptor, and vitamin D receptor also function as bile acid sensors to signal detoxification by hydroxylation of toxic bile acids. …”
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Antioxidant peptides encrypted in flaxseed proteome: An in silico assessment by Dawei Ji, Chibuike C. Udenigwe, Dominic Agyei

“…Compared with other enzymes studied, the plant proteases (papain, ficin, and bromelain) were found to be superior to releasing APs from the flaxseed proteins. Analysis of toxicity by ToxinPred showed that none of the peptides released was toxic. …”
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Colonialism and Historical Imagination by Tlhabane Mokhine ‘Dan’ Motaung

“…Fluid pre-colonial social ‘identities’ were recast and calcified into hide-bound, immutable and toxic ethnicity that was invested with a separatist consciousness underwritten by corresponding differential economic livelihoods. …”
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HDR Brachytherapy in the Management of High-Risk Prostate Cancer by Susan Masson, Raj Persad, Amit Bahl

“…We highlight practical aspects of delivering treatment and discuss toxicity and limitations, with particular reference to current practice in the United Kingdom.…”
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Successful Treatment of Adenovirus Infection with Brincidofovir in an Immunocompromised Patient after Hematological Stem Cell Transplantation by T. Van Genechten, J. van Heerden, T. Bauters, C. Dhooge

“…The increased efficacy of Brincidofovir (BCV) against multiple viral infections, limited toxicity, and oral-administered schedule opens options in different resource settings.…”
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The effect of AKT inhibition in α-synuclein-dependent neurodegeneration by Bedri Ranxhi, Zoya R. Bangash, Zachary M. Chbihi, Sokol V. Todi, Sokol V. Todi, Peter A. LeWitt, Peter A. LeWitt, Peter A. LeWitt, Wei-Ling Tsou

“…However, in PD, α-Syn cumulatively misfolds into toxic aggregates that disrupt cellular processes and contribute to neuronal damage and neurodegeneration. …”
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Hyperleukocytosis in a neuroblastoma patient after treatment with natural killer T cells expressing a GD2-specific chimeric antigen receptor and IL-15 by Xin Xu, Shantan Reddy, Saleh Bhar, Frederic D Bushman, Amy N Courtney, Gabriel A Barragán, Gengwen Tian, Erica J Di Pierro, Leonid S Metelitsa, Antonino Montalbano, Hangjin Yu, Claudia Martinez Amador, Nisha Ghatwai, Michael S Wood, Deborah Schady, Aoife M Roche, David de la Cerda, Donald Williams Parsons, Andras Heczey

“…The ability of immune cells to expand numerically after infusion distinguishes adoptive immunotherapies from traditional drugs, providing unique therapeutic advantages as well as the potential for unmanageable toxicities. Here, we describe a case of lethal hyperleukocytosis in a patient with neuroblastoma treated on phase 1 clinical trial (NCT03294954) with autologous natural killer T cells (NKTs) expressing a GD2-specific chimeric antigen receptor and cytokine interleukin 15 (GD2-CAR.15). …”
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Characterizations of Size-segregated Ultrafine Particles in Diesel Exhaust by Jaehyun Lim, Cheolsoo Lim, Sungwoon Jung

“…Two significant size ranges of toxicity equivalent quantity peaks in the ultrafine (34–66 nm) and accumulation (170–330 nm) modes were observed for the size-segregated DEPs. …”
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Toxicologic Assessment of a Commercial Decolorized Whole Leaf Aloe Vera Juice, Lily of the Desert Filtered Whole Leaf Juice with Aloesorb by Inder Sehgal, Wallace D. Winters, Michael Scott, Andrew David, Glenn Gillis, Thaya Stoufflet, Anand Nair, Konstantine Kousoulas

“…We tested a decolorized whole leaf (DCWL) aloe vera, treated with activated charcoal to remove the latex portion of the plant, for genotoxicity in bacteria, acute/subacute toxicity in B6C3F1 mice, and subchronic toxicity in F344 rats. …”
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Evaluation of the Hepatoprotective Properties of Traditional Formulations Based on Cochlospermum tinctorium Used in Benin by Appolinaire K. Dossa, Jean Robert Klotoé, Victorien Dougnon, Eric Agbodjento, Rémi Akotègnon, Fréjus Ohouko, Manoir Hounkanrin, Kévine Vodounnon, Luc V. C. Brun, Fréderic Loko

“…The results revealed an absence of acute oral toxicity for the 10 recipes. The hepatoprotective tests conducted indicated that the hepatoprotective effect of C. tinctorium is dose dependent. …”
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Prediction of the Binding to the Nuclear Factor NF-Kappa-B by Constituents from <i>Teucrium polium</i> L. Essential Oil by Renilson Castro de Barros, Renato Araújo da Costa, Nesrine Guenane, Boulanouar Bakchiche, Farouk Benaceur, Omer Elkiran, Suelem Daniella Pinho Farias, Vanessa Regina Silva Mota, Maria Fani Dolabela

“…All molecules were found to be toxic in at least one model, with some molecules being non-genotoxic (6, 8, 10, 11, 12, 13) and others being non-mutagenic (5, 7, 9, 14). …”
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Elevated Blood Ammonia Level Is a Potential Biological Risk Factor of Behavioral Disorders in Prisoners by Yunfeng Duan, Xiaoli Wu, Shan Liang, Feng Jin

“…Hydrothion (H2S) and ammonia (NH3) can be toxic for the human central nervous system and cause psychological disturbances and behavioral disorders. …”
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Dimethyl fumarate effects on paraquat-induced hepatotoxicity in mice via anti-oxidative, anti-inflammatory, and anti-apoptotic activities by Maryam Kavianinia, Hadi Kalantar, Maryam Salehcheh, Layasadat Khorsandi, Saeedeh Shariati, Shokooh Mohtadi, Mohammad Javad Khodayar

“…Abstract Paraquat (PQ) toxicity is a common problem in the world, associated with oxidative stress, inflammation, and apoptosis. …”
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Water-Soluble Vitamins: Hypo- and Hypervitaminosis in Pediatric Population by Roberto Paparella, Fabiola Panvino, Lucia Leonardi, Ida Pucarelli, Michela Menghi, Ginevra Micangeli, Francesca Tarani, Marcello Niceta, Debora Rasio, Rouzha Pancheva, Marco Fiore, Luigi Tarani

“…Conversely, although uncommon, excessive intake of certain water-soluble vitamins may cause mild toxicity, primarily gastrointestinal or neurological. …”
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Long-Term Safety of PEGylated Coagulation Factor VIII in the Immune-Deficient Rowett Nude Rat by Caroline E. Rasmussen, Jette Nowak, Julie M. Larsen, Emma Moore, David Bell, Kai Chiu Liu, Nanna Skall Sorensen, Wendela A. Kappers, Thomas Krogh-Meibom, Hanne Offenberg

“…Conducting long-term toxicity studies in animals using human proteins can be complicated by anti-drug antibody (ADA) development. …”
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Causal Relationship Between Emotional Disorders and Thyroid Disorders: A Bidirectional Two‐Sample Mendelian Randomization Study by Jiaying Fan, Kai Zhou, Cuiwen Yu

“…Results IVW results showed negative causal relationships between bidirectional emotional disorders and hypothyroidism, toxic single thyroid nodules in thyrotoxicosis, and hyperthyroidism/toxicity. …”
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Antimicrobial and Cytotoxicity Activities of Medicinal Plants against Salmonella gallinarum Isolated from Chickens by Mwanaisha Mkangara, Fulgence N. Mpenda

“…For the safety of chickens against the toxicity of plants, the cytotoxicity assay was determined using a brine shrimp lethality test. …”
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Macrofilaricidal Activity, Acute and Biochemical Effects of Three Lichen Species Found on Mount Cameroon by Thierry Roland Kang, Jerome Nyhalah Dinga, Ayuk Elizabeth Orock, Elvis Monya, Moses Njutain Ngemenya

“…No mortality and no adverse effects were recorded in the acute toxicity test. These two most active extracts had no significant effect on liver enzymes, alanine aminotransferase, and aspartate (P values < 0.05), but a high AST : ALT ratio (2.59) for Pammet indicates likely reversible adverse hepatic toxicity. …”
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Phytochemical Screening and In Vivo Antimalarial Activity of Two Traditionally Used Medicinal Plants of Afar Region, Ethiopia, against Plasmodium berghei in Swiss Albino Mice by Sibhatu Gebrehiwot, Mohammed Shumbahri, Amelework Eyado, Tilahun Yohannes

“…All extracts revealed no obvious acute toxicities on mice up to the highest (5000mg/kg) dose given. …”
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