Systematic Review of Focal Prostate Brachytherapy and the Future Implementation of Image-Guided Prostate HDR Brachytherapy Using MR-Ultrasound Fusion by M. Sean Peach, Daniel M. Trifiletti, Bruce Libby

“…Further, we wanted to determine if focal treatment results in less toxicity. Utilizing the Medline repository, dosimetric papers comparing whole gland to partial gland brachytherapy and clinical papers that reported toxicity of focal brachytherapy were selected. …”
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Hypoglycaemic, anti-hyperlipidemic, and anti-inflammatory activities of Asparagus africanus (Asparaceae) extract on high-fat diet/streptozotocin-induced diabetes in Wistar rats by Focham Evans Ngwenah, Oumar Mahamat, Tume Christopher

“…Objective: To investigate the toxicity and effect of the extract on some complications of diabetes in Wistar rats. …”
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Optimal treatment approach for intracranial germinoma: a systematic review and meta-analysis by Zhirui Zhou, Jiabing Liu, Qi Yue, Lingxiao Chen, Xiwei Zhang, Xin Lin, Lin Zheng, Enmin Wang, Yang Wang, Ying Mao

“…Total 24 studies reported treatment-related acute and/or late toxicity, combination CTx increased acute toxic, and expanded RT field and/or dose increased late toxicity. …”
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Accounting for microorganisms yields stricter water quality criteria and elevated ecological risks of antibiotics: A case study of sulfonamides in the Yangtze River Delta by Xinyang Zhang, Xiao Yun, Ye Huang, Guofeng Shen, Nan Lin

“…The derivation of water quality criteria (WQC) for antibiotics is influenced by the inclusion of various organisms' toxicity data, including microbial data, though no definitive conclusions have been reached. …”
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Novel organophosphate esters and their transformation products in offshore sediment from Eastern China: Occurrence, temporal trend, and risk assessment by Meng Gao, Yu Wang, Liman Wei, Siyuan Li, Qiuyue Zhang, Zhongkang Yang, Mohan Bai, Yiming Yao, Lei Wang, Hongwen Sun

“…Generally, the acute toxicity-based predicted no-effect concentrations for studied compounds were 1 to 2 orders of magnitude lower than those based on chronic toxicity. …”
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Creeping Indigo, A Poisonous Plant of Concern in Florida Pastures by Robert MacKay, Ed Jennings, Brent Sellers, Jason Ferrell, Amanda House

“… A recent rise in suspected horse poisonings has brought new attention to creeping indigo (Indigofera spicata), a toxic plant which has reportedly been in Florida for as long as 90 years. …”
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Study on the Application of Doxorubicin-Loaded Magnetic Nanodrugs in Targeted Therapy of Liver Cancer by Lei Wang, Liping Liang, Shuzhen Shi, Chao Wang

“…Doxorubicin (DOX) has been widely recognized as effective in anticancer therapy; however, the additional organ toxicity and low targeting of DOX in antitumor activity remains unaddressed. …”
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Creeping Indigo, A Poisonous Plant of Concern in Florida Pastures by Robert MacKay, Ed Jennings, Brent Sellers, Jason Ferrell, Amanda House

“… A recent rise in suspected horse poisonings has brought new attention to creeping indigo (Indigofera spicata), a toxic plant which has reportedly been in Florida for as long as 90 years. …”
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Impact of Hydrophobic Pollutants' Behavior on Occupational and Environmental Health by Ijeoma Kanu, Ebere Anyanwu

“…Their hazardous effects on organisms occur at varying spatial and temporal degrees of emissions, toxicities, exposures, and concentrations.…”
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Retargeting Clostridium difficile Toxin B to Neuronal Cells as a Potential Vehicle for Cytosolic Delivery of Therapeutic Biomolecules to Treat Botulism by Greice Krautz-Peterson, Yongrong Zhang, Kevin Chen, George A. Oyler, Hanping Feng, Charles B. Shoemaker

“…AGT-TcdB-BoNT/A-Hc was >25-fold more toxic to neuronal cells and >25-fold less toxic to Vero cells than AGT-TcdB. …”
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Safety Evaluation of Multiple Strains of Lactobacillus plantarum and Pediococcus pentosaceus in Wistar Rats Based on the Ames Test and a 28-Day Feeding Study by Cheng-Chih Tsai, Sew-Fen Leu, Quan-Rong Huang, Lan-Chun Chou, Chun-Chih Huang

“…In the short-term oral toxicity study, rats received a normal dosage of 390 mg/kg/d (approximately 9×109 CFU/kg/d) or a high dosage of 1950 mg/kg/d (approximately 4.5×1010 CFU/kg/d) for 28 d. …”
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Stereotactic Body Radiotherapy for Metastatic Lung Cancer as Oligo-Recurrence: An Analysis of 42 Cases by Wataru Takahashi, Hideomi Yamashita, Yuzuru Niibe, Kenshiro Shiraishi, Kazushige Hayakawa, Keiichi Nakagawa

“…To investigate the outcome and toxicity of stereotactic body radiotherapy (SBRT) in patients with oligo-recurrence cancer in the lung (ORCL). …”
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Expert consensus guidelines on management and best practices for tumor-infiltrating lymphocyte cell therapy by Sarah Nikiforow, John Haanen, Omid Hamid, Igor Puzanov, Rodabe Amaria, Amod Sarnaik, Marcus O Butler, Michael R Bishop, Allison Betof Warner, Adam J Schoenfeld, Krishna Komanduri

“…This review includes clinical and toxicity management guidelines pertaining to the TIL cell therapy regimen prepared by the TIL Working Group, composed of internationally recognized hematologists and oncologists with expertize in TIL cell therapy, and relates to patient care and operational aspects. …”
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Immunosuppressants in modern approaches to treatment of inflammatory bowel diseases by O. B. Schukina, A. G. Kharitonov, A. M. Kharitidis, T. E. Ivashchenko, Yu. A. Nasykhova, T. V. Gabrusskaya, A. Yu. Baranovsky

“…In case of intolerance or bone marrow toxicity at intake of thiopurines methotrexate should be prescribed.…”
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Cytotoxicity and In Vitro Antileishmanial Activity of Antimony (V), Bismuth (V), and Tin (IV) Complexes of Lapachol by Marcele Neves Rocha, Paula Monalisa Nogueira, Cynthia Demicheli, Ludmila Gonçalvez de Oliveira, Meiriane Mariano da Silva, Frédéric Frézard, Maria Norma Melo, Rodrigo Pedro Soares

“…Those compounds were moderately toxic for HepG2 cells and toxic for murine macrophages, still underlying the need of chemical modification in this class of compounds.…”
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Mechanism of mineral phase transformation in preparing aluminum alloy by electrolysis of molten salt from aluminum alloy dross by Zhengping Zuo, Wenfen Wu, Jianbo Zhang, Zhanbing Li, Fengqin Liu, Shaopeng Li

“…The electrochemical reduction method is an effective approach for the harmless treatment of toxic components in aluminum alloy dross (AAD) and the high-value utilization of valuable elements. …”
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Ozone-Catalytic Treatment of Automotive Exhaust by S.R. Khairulin, D.V. Maksudov, M.A. Kerzhentsev, A.V. Salnikov, Z.R. Ismagilov

“…Thus, the ozone concentration is maximum during a cold start, precisely when the lower temperatures do not allow other reactions than those of oxidation of toxic gases with ozone, and decreases by the time the catalytic unit warms up, when effective neutralization of toxic impurities becomes possible without the participation of ozone. …”
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Phytotoxicity and Benzoxazinone Concentration in Field Grown Cereal Rye (Secale cereale L.) by C. La Hovary, D. A. Danehower, G. Ma, C. Reberg-Horton, J. D. Williamson, S. R. Baerson, J. D. Burton

“…Results showed that rye tissue harvested in March was the most toxic to indicator species, with toxicity decreasing thereafter. …”
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EGFR inhibitors in the treatment of colorectal cancer by M. В. Zabelin, A. D. Kaprin, A. A. Kostin, E. V. Gameeva, S. E. Varlamova

“…The correla on between toxicity and effi  cacy of these drugs is discussed separately. …”
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Clopidogrel-Induced Neutropenia after Coronary Stenting: Is Cilostazol a Good Alternative? by Massimo Montalto, Italo Porto, Antonella Gallo, Claudia Camaioni, Roberta Della Bona, Antonio Grieco, Filippo Crea, Raffaele Landolfi

“…We report a case of clopidogrel-induced bone marrow toxicity manifesting with severe neutropenia in a patient treated with multiple coronary stents and provide suggestions for an alternative treatment.…”
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