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Larval Cytotoxic and Subacute Toxicity of Gardenia ternifolia, Rourea coccinea, and Cassytha filiformis Used in Traditional Medicine of Benin (West Africa)
Published 2020-01-01“…Unfortunately, very little data exist on the long-repeated dose toxicity of these medicinal plants. This study was aimed at evaluating the larval cytotoxicity and subacute toxicity of the hydroethanolic extract of Cassytha filiformis whole plant, Gardenia ternifolia roots, and Rourea coccinea leaves. …”
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662
The combined impacts of toxic drug use and the 2021 Heat Dome in Canada: A thematic analysis of online news media articles.
Published 2025-01-01“…<h4>Conclusion</h4>With increasing temperature extremes and a rising tide of toxic drug use and overdoses, our findings illustrate that there is a need for further research to better understand the combined impacts when toxic drug use, overdose-related deaths, and extreme heat coincide.…”
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663
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664
Antioxidant Potential, Subacute Toxicity, and Beneficiary Effects of Methanolic Extract of Pomelo (Citrus grandis L. Osbeck) in Long Evan Rats
Published 2019-01-01“…The aim of this study was to investigate the antioxidant potentials, subacute toxicity, and beneficiary effects of methanolic extract of pomelo (Citrus grandis L. …”
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665
Dietary Nannochloropsis oculata ameliorates lead acetate induced reproductive toxicity in Barki rams: NF-κB and cytokines pathways
Published 2025-01-01Subjects: Get full text
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666
Development of delayed pulmonary toxicities and transcriptional changes in pre-existing interstitial lung disease mice after partial thoracic irradiation
Published 2025-02-01“…No approved biomarker or medicine is available to prevent pulmonary toxicities in LC-ILD patients. Appropriate management for them remains a challenge for clinicians due to treatment-related complications. …”
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667
Pharmacogenomic profiling of variants affecting efficacy and toxicity of anti-infective medicines in a south Asian population from Sri Lanka
Published 2025-02-01“…Abstract Background Anti-infective medicines are crucial for treating infections, but improper dosing can cause toxicity, resistance and treatment failure. Pharmacogenomics can address genetic variations affecting drug efficacy and safety. …”
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668
Traffic-related-air-pollutant PM2.5 Caused Toxicity on Caenorhabditis elegans with Cotreatment of High-dose Glucose and Tempeh
Published 2022-12-01“…Using Caenorhabditis elegans (C. elegans) as an in vivo animal model, we found that exposure to 12.74 mg L−1 TRAP PM2.5 and 80 mM D-glucose could induce toxicity in nematodes that affects growth, reproduction, locomotion behavior, and lifespan. …”
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669
Potential Toxicity of the Essential Oil from Minthostachys mollis: A Medicinal Plant Commonly Used in the Traditional Andean Medicine in Peru
Published 2019-01-01“…For the acute toxicity test two groups of rats, of three animals each, were used. …”
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670
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Efficacy of Black Cumin (Nigella sativa) Ameliorate Organophosphate Toxicity in Pregnant Rats Based on Progesterone Levels and Fetal Bone Development
Published 2024-04-01“…This study aimed to evaluate black cumin activity ameliorates organophosphate toxicity in pregnant rats based on progesterone levels and fetal bone development. …”
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672
Toxicity of antimony in housefly after whole-life-cycle exposure: Changes in growth, development, redox homeostasis, mitochondrial function, and fecundity
Published 2025-01-01“…The disturbance of hormonal synthesis and the MAPK pathway induced by Sb treatment may contribute to reproductive toxicity. These comprehensive toxicological data provide insight into the prediction of toxicity and the assessment of the ecological risk of Sb.…”
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673
Application of Fish Embryo Assay Using Zebrafish and <i>Oryzias latipes</i> for Toxicity Testing and Deriving Water Quality Criteria
Published 2024-12-01“…However, due to increasing concerns about animal welfare and experimental ethics, there is a growing need for alternative methods to determine substance toxicity in fish. Fish toxicity tests using early life stages, such as embryos or larvae, have been utilized as alternative methods for adult fish toxicity assays. …”
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674
A multi-levels analysis to evaluate the toxicity of microplastics on aquatic insects: A case study with damselfly larvae (Ischnura elegans)
Published 2025-01-01“…However, the most diverse and sensitive aquatic insects are often overlooked, also there is a lack of a comprehensive research exploring the toxicity of microplastics. Here, taking the damselfly larvae (Ischnura elegans) as the subject, we investigated the effects of different concentration levels of polystyrene microplastics (PS MPs) on their physiological characters, behavioristics, metabolomics and transcriptomics, as well as gut microbiome. …”
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675
A sustainable breakthrough in rodent pest control: laboratory validation of novel neem-andrographolide bait with dual toxic and contraceptive effects
Published 2025-02-01“…Therefore, a neem seed and andrographolide-based bait (NSA bait) with both toxic and sterilising effects was developed for their long-term management. …”
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The real-world efficacy and toxicity of first-line paclitaxel and cisplatin with bevacizumab in platinum-naïve primary stage IVB cervical cancer
Published 2025-01-01“…Objective: To investigate the real-world efficacy and toxicity of paclitaxel-cisplatin-bevacizumab and identify prognostic factors for paclitaxel-cisplatin-bevacizumab in platinum-naïve primary stage IVB cervical cancer. …”
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678
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Case report: Toxic epidermal necrolysis as a unique presentation of acute graft versus host disease in a pediatric patient
Published 2025-01-01Subjects: “…toxic epidermal necrolysis…”
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680
New proposal for a multimodal imaging approach for the subclinical detection of hydroxychloroquine-induced retinal toxicity in patients with systemic lupus erythematosus
Published 2024-05-01“…A diagnosis of macular toxicity required the presence of abnormalities in at least one structural and functional test. …”
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