Antifungal, toxicological, and colorimetric properties of Origanum vulgare, Moringa oleifera, and Cinnamomum verum essential oils mixture against Egyptian Prince Yusuf Palace deter... by Asmaa Alhussein Mohamed, Mahgoub A. Ahmed, Abdallah S. Korayem, Samah H. Abu-Hussien, Wael Bakry Rashidy

“…Cytotoxicity testing on human skin fibroblasts (HSF) showed minimal toxicity of EOs mixture with 87.64% cell viability at 100 µg/ml. …”
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Development and validation of an LC-MS/MS method for the simultaneous estimation of tadalafil and macitentan in rat plasma: Greenness assessment and design of experiment approach by Sravanthi Gandu, Kumaraswamy Gandla, Lalitha Repudi

“…Environmental assessment using green analytical chemistry tools confirmed the eco-friendly design of the method, characterized by reduced solvent consumption and low toxicity. This validated LC-MS/MS method provides a robust and sustainable analytical solution for preclinical pharmacokinetic studies, delivering reliable data to inform safe and effective dosing of tadalafil and macitentan.…”
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Bone cell differentiation and mineralization in wild-type and osteogenesis imperfecta zebrafish are compromised by per- and poly-fluoroalkyl substances (PFAS) by Francesca Tonelli, Cecilia Masiero, Carla Aresi, Camilla Torriani, Simona Villani, Guido Premoli, Antonio Rossi, Antonella Forlino

“…Abstract Perfluorinated compounds (PFAS) are well recognized toxic pollutants for humans, but if their effect is equally harmful for healthy and fragile people is unknown. …”
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Survival after aluminum phosphide poisoning with cardiotoxicity: a case report by Habtamu Mesele Gebray, Addisu Liknaw Chekol

“…Because it is freely available on the market, it is one of the commonly used agents for self-poisoning in different parts of the developing world. Early signs of toxicity are manifested by shock and circulatory failure. …”
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Volatile Organic Compounds and Carbonyls Pollution in Mexico City and an Urban Industrialized Area of Central Mexico by Elizabeth Vega, Omar Ramírez, Gabriela Sánchez-Reyna, Judith C. Chow, John G. Watson, Diego López-Veneroni, Monica Jaimes-Palomera

“…A health risk assessment for toxic species such as benzene, toluene, ethyl benzene and xylenes (BTEX), found a decreasing trend from 2006 to 2012. …”
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Gaps in cancer care in a multi-ethnic population in Sarawak, Borneo: A central referral centre study. by Melissa Siaw Han Lim, Pei Jye Voon, Adibah Ali, Fitri Suraya Mohamad, Lin Lin Jong, Lee Ping Chew, Mohamad Adam Bujang, Yolanda Augustin, Yuong Kang Cheng

“…Many patients face financial toxicity following a cancer diagnosis, particularly when diagnosed with advanced cancer requiring complex multi-modality treatment.…”
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Synergistic attenuation of complete freund’s adjuvant-induced inflammation in mice using shinbaro-pelubiprofen: a novel therapeutic complex by Hyunseong Kim, Jin Young Hong, Wan-Jin Jeon, Hyun Kim, Changhwan Yeo, Junseon Lee, Yoon Jae Lee, In-Hyuk Ha

“…Additionally, while 1.5 mg/kg of Pel alone increases levels of liver and kidney toxicity markers, such as aspartate aminotransferase, alanine aminotransferase, and creatinine, combining it with SBR at a reduced dosage of 0.5 mg/kg maintains these markers at normal levels. …”
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Eco‐sustainable printing of cellulosic polymeric material using bio‐colorants and bio‐crosslinkers by Faisal Ahmed, Md. Reazuddin Repon, Arnob Dhar Pranta, Md. Sayed Ragib Yasar, Md. Faisal Rakib, Ishtiak Ahmed, Toufiq Ahmed Emon, Tarakul Alam Nishat

“…Abstract A sustainable solution to lessen environmental damage, improve health and fulfill the increasing need for environmentally conscious goods might be for the textile industry to use eco‐friendly printing techniques and natural colors. Without the use of toxic metal‐based mordants, this research work set out to examine how natural thickeners, biomordants, and dyes interacted when printed on cotton knit fabric. …”
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Efficient and Rapid Microfluidics Production of Bio-Inspired Nanoparticles Derived from <i>Bombyx mori</i> Silkworm for Enhanced Breast Cancer Treatment by Muhamad Hawari Mansor, Zijian Gao, Faith Howard, Jordan MacInnes, Xiubo Zhao, Munitta Muthana

“…In vitro studies demonstrated sustained cytotoxic effects, and cell cycle arrest at the G2/M phase in breast cancer cell lines, with minimal toxicity in non-cancerous cells. Cellular uptake assays confirmed efficient drug delivery to the cytoplasm. …”
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Structure-Based Virtual Screening, Docking, ADMET, Molecular Dynamics, and MM-PBSA Calculations for the Discovery of Potential Natural SARS-CoV-2 Helicase Inhibitors from the Tradi... by Ahmed M. Metwaly, Alaa Elwan, Abdul-Aziz M. M. El-Attar, Sara T. Al-Rashood, Ibrahim H. Eissa

“…Then, the most appropriate 26 compounds were subjected to in silico ADMET and toxicity studies to select the most convenient inhibitors to be: (1R,2S)-ephedrine (57), (1R,2S)-norephedrine (59), 2-(4-(pyrrolidin-1-yl)phenyl)acetic acid (84), 1-phenylpropane-1,2-dione (195), 2-methoxycinnamic acid (246), 2-methoxybenzoic acid (364), (R)-2-((R)-5-oxopyrrolidin-3-yl)-2-phenylacetic acid (405), (Z)-6-(3-hydroxy-4-methoxystyryl)-4-methoxy-2H-pyran-2-one (533), 8-chloro-2-(2-phenylethyl)-5,6,7-trihydroxy-5,6,7,8-tetrahydrochromone (637), 3-((1R,2S)-2-(dimethylamino)-1-hydroxypropyl)phenol (818), (R)-2-ethyl-4-(1-hydroxy-2-(methylamino)ethyl)phenol (5159), and (R)-2-((1S,2S,5S)-2-benzyl-5-hydroxy-4-methylcyclohex-3-en-1-yl)propane-1,2-diol (5168). …”
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Assessment Of Heavy Metals Concentration and Pollution Indices Of Surface Water In Enerhen River, Warri South LGA, Delta State, Nigeria by A. O. Egai, M. Paaru

“…Data obtained show that the result indicated the concentration of Zinc 0.065mg/l - 0.190mg/l, Pb (0.003mg/l -0.142mg/l), Cu (0.081mg/l - 0.213mg/l), Cd (0.02mg/l - 0.282mg/l, Cr (0.041mg/l - 0.171mg/l), Fe (0.162mg/l - 0.278mg/l) and Ni (0.104mg/l - 0.762mg/l)  comparison with WHO 2012 permissible limit the probed water sample falls within the allowable concentration of the standard except the  concentration of lead (Pb) in SW1, SW2, SW4 and SW5 which is a  concern because it exceeded the allowable limit, lead is considered toxic to human at higher concentrations . The computed indices for the maximum admissible concentration upper permissible values buttress as follows Zn 0.3MAC, Pb 0.01MAC, Cu 2MAC, Cd 0.01MAC, Cr 0.05MAC, Fe, 0.3MAC and Ni 0.02MAC. …”
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Regulation of innate immune response by miRNAs up-regulated in Stevens-Johnson syndrome with severe ocular complications by Mayumi Ueta, Hiromi Nishigaki, Hokoru Yoshioka, Shigeru Kinoshita, Chie Sotozono

“…Abstract Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe mucocutaneous disorders characterized by extensive tissue necrosis; they are often accompanied by severe ocular complications (SOC). …”
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Elevated concentrations of quaternary ammonium compounds in childcare centers: A pilot study by Yao Cheng, Zhong Lv, Erika Schreder, Min Hu, Abby Mutic, Guomao Zheng, Amina Salamova

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Efficacy and safety of pembrolizumab in patients with advanced endometrial cancer: a systematic review and meta-analysis by Biqiong Pan, Xiaojun Lai, Jiefang Lu, Xiaoyan Bao, Zengke Fan, Jie Sun

“…Two randomized controlled trials (RCTs) found that the pembrolizumab group had a higher incidence of grade 3 or 4 AEs compared to the control group (OR: 2.23; 95% CI: 1.23, 4.04; p = 0.008).ConclusionPembrolizumab monotherapy or combination significantly improves survival in recurrent or advanced EC and has manageable toxicity albeit with a relatively high incidence of treatment-related AEs.…”
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Reduction of bioavailability and leachability of heavy metals during agitated pile composting of Salvinia natans weed of Loktak lake by W. Roshan Singh, Shashi Kumar Pankaj, Ajay S. Kalamdhad

“…The study also revealed that the total concentrations of Zn (211â254 mg/ kg), Ni (310â345 mg/kg) and Pb (805â891 mg/kg) of the final composts were higher than that of Cr (140â207 mg/ kg) but the water-soluble forms of Zn (3.6â4.7 % of total Zn), Ni (NIL) and Pb (0.7â1.0 % of total Pb) were lower than that of Cr (13.3â19.3 % of total Cr) indicating that Cr in the composts had higher toxicity potential. The leachable heavy metals were within the threshold limits prescribed for agricultural application. …”
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Competitive Pasture Species to Suppress the Growth of Annual Riceflower (<i>Pimelea trichostachya</i> Lindl.) at Different Planting Densities and Spatial Arrangements by Rashid Saleem, Ali Bajwa, Shane Campbell, Mary T. Fletcher, Sundaravelpandian Kalaipandian, Steve W. Adkins

“….), and buffel grass (<i>Pennisetum ciliare</i> L.) against the toxic annual riceflower (<i>Pimelea trichostachya</i> Lindl.) at varying planting densities and ratios. …”
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Advancing global herbal medicine: Enhancing herb quality through innovative strategies explored in Hong Kong - An international hub by Hiu-Lam Ngai, Pang-Chui Shaw

“…Herbs have been identified recurrently to have problems such as over-limit aflatoxins and toxic alkaloids, and the distributors had to recall the problematic herbs. …”
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Nursing knowledge in cardio-oncology: results of an international learning needs-assessment survey by Anecita Fadol, Geraldine Lee, Valerie Shelton, Kelly C. Schadler, Asma Mohammed Younus, Mary Stuart, Lisa Nodzon, Edith Pituskin

“…In relation to specific cardio-oncology topics, there was a strong interest in learning more about specific cardiovascular toxicities, and their monitoring and management (n = 205, 66%). …”
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Improvement of engineering properties and environmental impact of fired clay bricks utilizing industry sludge waste by Amir Detho, Aeslina Abdul Kadir, Ahmad Shayuti, Bin Abdul Rahim, Nejib Ghazouani, Abdelkader Mabrouk, Ahmed Babeker Elhag, Hesham Hussein Rassem

“…Various leachability assessments, including the Toxicity Characteristic Leaching Procedure (TCLP), Synthetic Precipitation Leaching Procedure (SPLP), and Static Leachate Test (SLT), confirm that bricks containing up to 30% BS and PS comply with United States Environmental Protection Agency (USEPA) and Environment Protection Authority Victoria (EPAV) standards for heavy metals, making them environmentally safe for use. …”
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Antimicrobial photodynamic inactivation of Pseudomonas aeruginosa persister cells and biofilms by Mona Mahmoud, Peter Richter, Philipp Arnold, Michael Lebert, Andreas Burkovski

“…Nevertheless, the addition of BP did not enhance the efficacy of CHL against biofilms; CHL (500 µg/ml) reduced biofilm viability by 2.6 log10 at 791 J/cm2. No toxicity has been observed in darkness. This study highlights the potential antimicrobial effect of CHL against P. aeruginosa.…”
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