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4161
Analysis of thyroid function and structure and serum metabolomics in pregnant rats exposed to airborne contaminants: Combined perchlorate, thiocyanate, and nitrate exposure
Published 2025-01-01“…Conclusions: Mixed thiocyanate, nitrate, and perchlorate exposure can result in subchronic toxicity in rats, affecting thyroid function and structure.…”
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4162
Effect of antioxidant capsule supplementation on oxidative stress markers in hypertensive patients
Published 2024-01-01“…A high antioxidant diet could scavenge the free radicals and other toxic radicals offering better protection to the cardiovascular system. …”
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4163
Multiple use of preservative-free single dose unit dexamethasone 0.1% eye drops is safe within 24 hours
Published 2024-07-01“…Background Unpreserved single-dose unit (SDU) eye drops are commonly used to avoid benzalkonium chloride-related toxicity. Although intended for single use, many patients report off-label repeated use of SDUs over a prolonged period. …”
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4164
Association between HLA-B Alleles and Carbamazepine-Induced Maculopapular Exanthema and Severe Cutaneous Reactions in Thai Patients
Published 2018-01-01“…The HLA-B∗15:02 allele has been reported to have a strong association with carbamazepine-induced Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) in Thai patients. …”
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4165
Acute Neurotoxicity in Children Treated for Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma: A 10-Year Single-Centre Experience
Published 2024-12-01“…<b>Background</b>: Recent advances in childhood acute lymphoblastic leukemia (ALL) and lymphoblastic lymphoma (LL) management provide higher survival rates at the cost of increased toxicities. Acute neurotoxicity affects up to 10% of patients, requiring rapid recognition and treatment. …”
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4166
Influence of alcohol blend fuels on performance and noise emission in spark ignition engine
Published 2025-03-01“…Additionally, adding ethanol reduces toxic exhaust particles. Pure gasoline had a lower heating value, but ethanol was shown to improve all other engine fuel qualities. …”
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4167
Effects of fermented Artemisia annua on the intestinal microbiota and metabolites of Hu lambs with naturally infected with Eimeria spp.
Published 2025-01-01“…Chemical drugs are the primary method of treating sheep coccidiosis, but their use will bring drug resistance, toxic side effects, drug residues, and other problems. …”
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4168
Cobalt oxide nanoparticles induce cytotoxicity and excessive ROS mediated mitochondrial dysfunction and p53-independent apoptosis in melanoma cells
Published 2025-01-01“…Abstract Nanotherapy has emerged as a promising strategy for the targeted and efficient treatment of melanoma, the most aggressive and lethal form of skin cancer, with minimized systemic toxicity. However, the therapeutic efficacy of cobalt oxide nanoparticles (Co3O4NPs) in melanoma treatment remains unexplored. …”
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4169
Curcumin and α/β-Adrenergic Antagonists Cotreatment Reverse Liver Cirrhosis in Hamsters: Participation of Nrf-2 and NF-κB
Published 2019-01-01“…However, several studies suggest that the toxicity generated by metabolism of these antagonists would hinder its use in cirrhotic patients. …”
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4170
Ecotoxicological insight of phytochemicals, toxicological informatics, and heavy metal concentration in Tridax procumbens L. in geothermal areas
Published 2024-01-01“…Toxicological analysis showed that the compounds in the ethanolic extract of Tridax procumbens were nontoxic or inactive in five toxicity parameters. The other results of the heavy metal analysis showed the dominance of chromium among the other six metals tested (copper, not detected; cadmium, 0.91 ± 0.03 milligram per kilogram; zinc, 3.50 ± 0.03 milligram per kilogram; iron, 4.65 ± 0.02 milligram per kilogram; lead, 6.42 ± 0.05 milligram per kilogram; and chromium, 13.81 ± 0.07 milligram per kilogram.CONCLUSION: This study highlights the unique secondary metabolite composition of Tridax procumbens under such extreme conditions and underscores the potential implications of heavy metal accumulation in plants in geothermal areas.…”
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4171
Antifungal, Insecticidal, and Repellent Activities of Rosmarinus officinalis Essential Oil and Molecular Docking of Its Constituents against Acetylcholinesterase and β-Tubulin
Published 2024-01-01“…Repellent capacity and toxicity were evaluated through inhalation and contact tests on Callosobruchus maculatus. …”
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4172
Optimization, characterization and biosafety of oregano, rosemary and mint oil mixture against Penicillium digitatum in citrus using L-optimal mixture design
Published 2025-01-01“…Histological analysis indicated low toxicity to the liver at the highest tested concentration (1% mixture). …”
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4173
The Role of Duodenogastroesophageal Reflux in the Progression of Gastroesophageal Reflux Disease: From Esophagitis to Adenocarcinoma
Published 2024-08-01“…Ursodeoxycholic acid (UDCA), a hydrophilic bile acid, is a natural competitive inhibitor of DCA and prevents DNA damage and nuclear factor-κB (NF-κB) activation caused by toxic bile acids in BE epithelial cells. The cytoprotective effect of UDCA, aimed at preventing DNA damage and increasing the reparative capacity of cells in the metaplastic epithelium of the BE, allows us to consider this drug as a means of chemoprophylaxis in patients diagnosed with GERD.Conclusion. …”
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4174
Early Biomarkers for Detecting Subclinical Exposure to Fumonisin B1, Deoxynivalenol, and Zearalenone in Broiler Chickens
Published 2024-12-01“…This study aimed to identify whether serum enzyme concentrations, gut integrity, and liver miRNAs can be potential biomarkers for fumonisin B1 (FB1), deoxynivalenol (DON), and zearalenone (ZEA) toxicity in broiler birds as early as 14 days after exposure. …”
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4175
Investigation of Mechanical and Tribological Characteristics of Medical Grade Ti6al4v Titanium Alloy in Addition with Corrosion Study for Wire EDM Process
Published 2022-01-01“…Metals used in biomedical applications are frequently coated to prevent oxidation and metallic ion release, both of which can be harmful due to toxic effects. To prevent these adverse effects of metals, researchers have focused their efforts on developing various coating techniques, facilitating surface coating, or obtaining functional surfaces. …”
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4176
Fast Rate Production of Biodiesel from Neem Seed Oil Using a Catalyst Made from Banana Peel Ash Loaded with Metal Oxide (Li-CaO/Fe2 (SO4)3)
Published 2020-01-01“…Biodiesel is a possible remedy to the present toxic, finite sources and ever-diminishing crude fuels. …”
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4177
Nanoparticles for Biomedical Use Derived from Natural Biomolecules: Tannic Acid and Arginine
Published 2025-01-01“…Furthermore, all p(TA-co-ARG) particles at 1000 mg/mL concentration showed >80% toxicity on L929 fibroblast cells and increased as ARG content of p(TA-co-ARG) particles is increased. …”
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4178
Blue applicability grade index assessment and response surface modelling to synchronous determination of metformin hydrochloride, vildagliptin and dapagliflozin propanediol monohyd...
Published 2025-02-01“…But these chromatographic analyses promoted usage of toxic organic solvents which are harmful to the environment and aquatic animal lives. …”
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4179
Impact of Agroindustrial Waste Fermented with Bacteria and Yeasts and Their Effect on Productive, Hematological, and Microbiota Indicators in Guinea Pigs (<i>Cavia porcellus</i>)
Published 2025-01-01“…Results: The parameters evaluated were toxicity, productive parameters, occurrence of diarrhea and mortality, and blood profile. …”
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4180
Mycosynthesis of chitosan-selenium nanocomposite and its activity as an insecticide against the cotton leafworm Spodoptera littoralis
Published 2025-01-01“…Selenium nanoparticles (SeNPs) are metalloid nanomaterial, with extensive biological activities. They have low toxicity and can be used safely in plant disease management. …”
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