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4061
Morphological features of bovine placenta in case of viral, bacterial and protozoal infections
Published 2022-06-01“…Chlamydia abortus intrauterine infection in the “mother – placenta – fetus” system in cows causes a complex of destructive morphological and functional changes of an infectious and toxic nature with a pronounced inflammatory reaction, involvement of blood vessels in the pathological process, and endothelial dysfunction development, alongside with tissue necrosis in case of a chronic process. …”
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4062
A bibliometric analysis of the effects of electronic waste on the environment
Published 2022-10-01“…The study adds valuable insights to the body of literature in hazardous and toxic substances management. No studies were found chronicling the environmental effects of e-waste using bibliometric analysis. …”
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4063
Paper Bags vis-à-vis LDPE Bags: Gleanings from Peer-reviewed E-LCA Publications
Published 2023-08-01“…Environmental impact categories include the global warming potential, energy demand, fossil fuel depletion, water usage, acidification, eutrophication, and a range of toxicities – human, terrestrial, freshwater-aquatic and marine-aquatic. …”
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4064
Antitumor Effect of Demethylzeylasteral (T-96) on Triple-Negative Breast Cancer via LSD1-Mediate Epigenetic Mechanisms
Published 2022-01-01“…And T-96 could significantly inhibit tumor growth without showing marked toxicity. Conclusions & Implications. The results illustrated that T-96 exerted antitumor activity in highly metastatic TNBC by inactivating the LSD1 function.…”
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4065
Exploring Clec9a in dendritic cell-based tumor immunotherapy for molecular insights and therapeutic potentials
Published 2025-02-01“…Consequently, these actions may contribute to reduced toxicity and enhanced treatment efficacy in immunotherapy. …”
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4066
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4067
Aflatoxin B1: Challenges and Strategies for the Intestinal Microbiota and Intestinal Health of Monogastric Animals
Published 2025-01-01“…Mycotoxin-detoxifying agents include mycotoxin-adsorbing agents, such as clay and yeast cell wall compounds, binding to AFB<sub>1</sub> and mycotoxin-biotransforming agents, such as specific strains of <i>Bacillus subtilis</i> and mycotoxin-degrading enzyme, degrading AFB<sub>1</sub> into non-toxic metabolites such as aflatoxin D1. Multiple mycotoxin-detoxifying agents are often combined and used together to improve the intestinal health and growth of chickens and pigs fed AFB<sub>1</sub>-contaminated feeds. …”
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4068
Continuous Improvements and Future Challenges of Air Pollution Control at an Advanced Semiconductor Fab
Published 2023-04-01“…A wide range of air pollutants is emitted from various sources classified as organic solvents, corrosive, toxic and combustible gases. This effective strategy employs a two-stage treatment method to comply with national emission regulations. …”
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4069
Potential Antioxidant Activity of New Tetracyclic and Pentacyclic Nonlinear Phenothiazine Derivatives
Published 2016-01-01“…The results suggest that phenothiazine derivatives, especially 6-chloro-11-azabenzo[a]phenothiazine-5-one, possess antioxidant activity though 6-[4-bromophenyl]-10-methyl-11-azabenzo[a]phenothiazine-5-one was slightly toxic. This activity may be due to the presence of electron donors such as sulfur as well as the richness of hydrogen in the additional benzene rings for substitution. …”
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4070
The Effects of Adverse Events and Associated Costs on Value-Based Care for Metastatic Pancreatic Ductal Adenocarcinoma
Published 2024-12-01“…We compared the incidence of clinically significant AEs, TCOC, components of TCOC, and costs related to AEs/treatment toxicity. **Results:** Patient AE rates ranged from 6.2% to 51.7%. …”
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4071
PARP inhibitors as therapy for small cell lung carcinoma: A systematic review and meta-analysis of clinical trials
Published 2024-01-01“…Amongst the hematologic toxicities, sub-analysis showed that thrombocytopenia had the highest risk, followed by neutropenia, anemia, leukopenia, and lymphopenia. …”
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4072
Complex immunotoxic effects of T-2 Toxin on the murine spleen and thymus: Oxidative damage, inflammasomes, apoptosis, and immunosuppression
Published 2025-01-01“…T-2 toxin (T-2), a highly stable and toxic mycotoxin, poses a significant public health risk as an inevitable environmental pollutant. …”
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4073
Antitumor effect of Bothrops jararaca venom
Published 2002-01-01“…In vitro treatment with BjV produced a dose-dependent toxic effect on EAT and peritoneal cells, with higher effects against peritoneal cells. …”
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4074
Development and Characterization of Chitosan Nanoparticles Loaded with Amoxicillin as Advanced Drug Delivery Systems against Streptococcus Mutans
Published 2025-01-01“…The resultant nanocomposite can be put to use as an effective, non-toxic antimicrobial agent. CMCS has a considerably wider range of uses as an anti-bacterial agent than chitosan since it is soluble in a wide pH range. …”
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4075
Cold Ceramic in Endodontics Treatments: A Review
Published 2024-12-01“… Introduction: Cold Ceramic (CC) is designed to meet the ideal criteria for root filling materials, offering effective sealing, biocompatibility, non-toxicity, dimensional stability, insolubility in tissue fluids, radiopacity, and ease of handling. …”
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4076
Ginkgetin delays the progression of osteoarthritis by inhibiting the NF-κB and MAPK signaling pathways
Published 2025-02-01“…Ginkgetin (GK), a natural non-toxic chemical, has proven anti-inflammatory, antioxidant, anti-tumor, and neuroprotective effects. …”
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4077
To Compare and Evaluate the Efficacy of 1% Alendronate Gel and 10% Doxycycline Gel as an Adjunct to SRP in Patients with Chronic Periodontitis: A Randomized Controlled Clinical Tri...
Published 2024-12-01“…This method offers advantages over systemic delivery, such as reduced dosage and frequency, minimized systemic toxicity, and the avoidance of gastrointestinal issues and first-pass metabolism. …”
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4078
Assessment of liver fibrosis by acoustic radiation force impulse elastography in rheumatic disease patients on long-term methotrexate treatment
Published 2020-01-01“…Conclusion: Considering the risk and benefit ratio of liver biopsy, ARFI may be a useful non- invasive diagnostic tool for the monitoring hepatic toxicity in patients with rheumatic disease undergoing methotrexate treatment.…”
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4079
The Benefits of Adding Sulfur and Urea to a Concentrate Mixture on the Utilization of Feed, Rumen Fermentation, and Milk Production in Dairy Cows Supplemental Fresh Cassava Root
Published 2022-01-01“…Sulfur might detoxify hydrogen cyanide toxicity and be added at 20 g/kg DM in concentrate without harming the animals, whereas urea at 20 g/kg DM could increase feed digestion and rumen fermentation.…”
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4080
Long-chain chlorinated paraffins (LCCPs) exposure induces apoptosis in primary chicken embryo hepatocytes through oxidative stress
Published 2025-01-01“…In conclusion, the current work shows that LCCPs have multiple toxic effects on primary chicken embryo hepatocytes, and lays a theoretical foundation for future research on the harmful effects of LCCPs in the poultry industry.…”
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