Synthesis of Silver and Zinc Oxide Nanoparticles Using Polystichum lentum Extract for the Potential Antibacterial, Antioxidant, and Anticancer Activities by Deepak Kumar Shrestha, Akash Budha Magar, Manisha Bhusal, Rabina Baraili, Ishwor Pathak, Pusp Raj Joshi, Niranjan Parajuli, Khaga Raj Sharma

“…Both nanoparticles and aqueous extract were mildly toxic towards the brine shrimp nauplii with the lowest LC50 being 661.80 ± 64.21 μg/mL for the aqueous extract. …”
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Mixture of MMP-2, MLC, and NOS Inhibitors Affects NO Metabolism and Protects Heart from Cardiac I/R Injury by Anna Krzywonos-Zawadzka, Aleksandra Franczak, Grzegorz Sawicki, Iwona Bil-Lula

“…Increased production of toxic peroxynitrite (ONOO−) during oxidative stress is a source of increased nitration/nitrosylation of contractile proteins, which enhance their degradation through MMP-2. …”
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In Silico and In Vitro Inhibitory Activity of Indonesian Herbal Compound Extracts against SARS-COV-2 Recombinant Papain-Like Protease by Fairuz Andini Fatiningtyas, Riswanto Napitupulu, Amarila Malik, Is Helianti

“…The physicochemical characteristics affecting absorption, distribution, metabolism, excretion, and toxicity (ADMET) were determined using the pkCSM descriptor algorithm protocol. …”
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Construction of Shoot Apical Meristem cDNA Yeast Library of <i>Brassica napus</i> L. and Screening of Proteins That Interact with the Inflorescence Regulatory Factors BnTFL1s by Lingxiong Zan, Haidong Liu, Xutao Zhao, Dezhi Du, Kaixiang Li

“…Additionally, the bait vector pGBKT7-BnTFL1s was transformed into yeast cells alongside positive and negative controls, demonstrating no toxicity to the yeast cells and no self-activation. …”
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Purification and Characterization of Hemagglutinating Proteins from Poker-Chip Venus (Meretrix lusoria) and Corbicula Clam (Corbicula fluminea) by Chin-Fu Cheng, Shao-Wen Hung, Yung-Chung Chang, Ming-Hui Chen, Chen-Hsuan Chang, Li-Tse Tsou, Ching-Yu Tu, Yu-Hsing Lin, Pan-Chen Liu, Shiun-Long Lin, Way-Shyan Wang

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In vitro evaluation of glutathione implementation on oxidative dna damage and oxidant status in high glucose conditions by Fatmagul Yur, Semiha Dede, Sedat Cetin, Mehmet Taspinar, Ayse Usta

“…On the other hand, it was revealed that the applied amounts of glutathione in the process did not cause any toxic effects.…”
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Effects of fiber engraving laser on metallurgical, surface topography, and corrosion properties of AZ80 magnesium-based alloy by Narges Ahmadi, Homam Naffakh-Moosavy, Seyed Mohammad Mahdi Hadavi, Fatemeh Bagheri

“…Magnesium, a lightweight metal similar to natural bone, shows no toxicity and can aid in hard tissue recovery when implanted in the human body. …”
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Rationale and design of the multicenter, national, randomized, open labeled phase III trial: allogeneic stem cell transplantation as a potential curative treatment for patients wit... by Annemarie Glöckner, Stefan Schönland, Hermann Einsele, Nicolaus Kröger

“…Discussion The present clinical study is designed to evaluate the superiority of allogeneic stem cell transplantation compared to conventional therapy (triplet chemotherapy) for the difference in overall survival at 5 years, toxicity and quality of life in patients with multiple myeloma who have relapsed or progressed after first-line autologous stem cell therapy. …”
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Economic Spectrofluorometric Bioanalysis of Empagliflozin in Rats’ Plasma by Bassam Ayoub, Noha El Zahar, Haidy Michel, Mariam Tadros

“…Moreover, development of new simple cost-effective methods is necessary to give the researchers a set of “varieties” that they can use according to the laboratory limitations, especially in the developing countries in addition of being a greener method due to the lower consumption of toxic solvents and lower waste production.…”
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A rare case of acute myocardial infarction with heart failure following hump-nosed viper bite in a Sri Lankan female by W. M. D. A. S. Wanninayake, Tilan Aponso, Manohari Seneviratne, Dhanapala Dissanayake

“…However, recent reports have indicated severe systemic envenomation incidents, which include hemostatic dysfunction, microangiopathic hemolysis, kidney injury, myocardial toxicity, and even death. The literature rarely reports cardiac manifestations from hump-nosed viper bites, and all reported cases show cardiac manifestations within hours of the snake bite. …”
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High-field MRI findings in epileptic dogs with a normal inter-ictal neurological examination by Stephanie Phillipps, Rita Goncalves

“…To be included in the study, patients had to have a normal neurological examination, high-field MRI of the brain and have had metabolic and toxic causes excluded.ResultsFour hundred and twelve dogs were eligible for inclusion. …”
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Assessment of Health Risks in Wheat Crop Irrigated by Manka Canal, Dera Ghazi Khan, Pakistan by Muhammad Anwar ul Hassan, Sabiha Javied, Umair Riaz, Muneera A. Saleh, Khalid H. Alamer, Naila Siddique, Ambreen Aslam, Nabeela Noor, Qamar uz Zaman

“…Prior to irrigating crops like wheat and vegetables, it is strongly advised to treat municipal wastewater to prevent soil and dietary toxicity from heavy metals.…”
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Pharmacological pain management in patients with rheumatoid arthritis: a narrative literature review by Natasha Cox, Christian D. Mallen, Ian C. Scott

“…Consequently, pain care is often suboptimal, with growing evidence that analgesics are widely prescribed to patients with RA, despite potential toxicities and limited evidence for efficacy. Our review provides an overview of pharmacological treatments for pain in patients with RA, summarising their efficacy and use. …”
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Effects of shrimp chitosan based edible coating on the shelf life of selected vegetables in context of attaining SDGs by Munir Ibn Mahin, Md. Harun-Ar Rashid, Abdul Rabbi Mredul

“…Polysaccharide coatings, particularly chitosan, have gained popularity as biopolymer-based coatings for prolonging the postharvest shelf life of fruits and vegetables, owing to their biodegradable and non-toxic properties. This study aimed to assess the characteristics of chitosan obtained from shrimp (Penaeus monodon) shells and uses it as coatings to prolonging the shelf life of tropical vegetables. …”
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Genome wide identification of MATE and ALMT gene family in lentil (Lens culinaris Medikus) and expression profiling under Al stress condition by Ankita Tripathi, Dharmendra Singh, Jyotika Bhati, Deepti Singh, Jyoti Taunk, Jawaher Alkahtani, Abdulrahman Al-Hashimi, Madan Pal Singh

“…Abstract Background The membrane transporters viz. multidrug and toxic compound extrusion (MATE) and aluminum-activated malate transporter (ALMT) are associated with aluminum (Al) tolerance by accelerating secretion of organic acids, which can influence nutrient availability and stress response. …”
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Effect of Essential Microelements on Proteomic Profile of Lamb Muscle Tissue Protein by Tatiana M. Giro, Andrey V. Kulikovsky, Anna V. Giro

“…The samples contained glutathione-S-transferase, which is responsible for biotransformation of toxic compounds, maintenance of intracellular homeostasis, and stress resistance. …”
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Design and In Silico and In Vitro Evaluations of a Novel Nicotinamide Derivative as a VEGFR-2 Inhibitor by Ibrahim H. Eissa, Muhammad Abd ElGayed Bkrah, Reda G. Yousef, Hazem Elkady, Eslam B. Elkaeed, Bshra A. Alsfouk, Ibrahim M. Ibrahim, Ahmed M. Metwaly, Dalal Z. Husein

“…Furthermore, compound 10 demonstrated a lower level of toxicity towards Vero cell lines, with an IC50 value of 127.3 μM. …”
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Safety assessment of the substance 2,2′‐oxydiethylamine for use in plastic food contact materials by EFSA Panel on Food Contact Materials (FCM), Claude Lambré, Riccardo Crebelli, Maria deSilva, Konrad Grob, Evgenia Lampi, Maria Rosaria Milana, Marja Pronk, Mario Ščetar, Georgios Theodoridis, Els Van Hoeck, Nadia Waegeneers, Claudia Bolognesi, Ronan Cariou, Laurence Castle, Emma Di Consiglio, Roland Franz, Eric Barthélémy, Remigio Marano, Gilles Rivière

“…Based on these data, the Panel excluded genotoxicity concerns for the substance and its oligomers. From a 90‐day toxicity study on the 1‐oxa‐4,11,18‐triazacycloeicosane‐5,10,17‐trione, the Panel identified a NOAEL of 1040 mg/kg bw per day. …”
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Rapid microcystin-LR detection using antibody-based electrochemical biosensors with a simplified calibration curve approach by Samuel Adjei-Nimoh, Lance-Nicolas Rances, Maha A. Tony, Hossam A. Nabwey, Woo Hyoung Lee

“…Abstract Harmful algal blooms (HABs) can release cyanotoxins such as microcystins (MCs), especially, microcystin-leucine-arginine (MC-LR) which is one of the commonest and most toxic, into our water bodies and can lead to several acute or chronic diseases such as liver diseases and respiratory irritation in humans. …”
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Evaluation of community behavior regarding the risk of plastic micro-pollution on the environment health by D. Utari, N.I. Hawa, G. Fizumli, H. Agustina

“…This research aims encourage greater awareness of environmental condition to minimize toxicity resulting from the negative impacts of plastic waste.…”
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