Using the Circular Economy to Mitigate the Global Electronic Waste Challenge: A Systematic Literature Review Approach by Mfowabo Maphosa, Vusumuzi Maphosa

“… The global electronic waste (e-waste) output is increasing at an alarming pace, albeit with limited management practices, resulting in the release of toxic anthropogenic elements that threaten the environment and public health. …”
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Recent insights into the transformative role of Graphene‐based/TiO2 electron transport layers for perovskite solar cells by T. Sewela, R. O. Ocaya, T. D. Malevu

“…The high interest in TiO2 is due to its low toxicity, chemical stability, and the potential to enhance its excitonic performance through doping with many materials. …”
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Pesticide application and water quality in Doho and Kibimba rice irrigation schemes, eastern Uganda by Sulaiman, Abubakar Aminua, Sarah, Nachuha, Zakia, Tebetyoc

“…The number and amount of agrochemicals used has increased dramatically world over and their toxic nature has raised concern about environmental impact and effects on human health. …”
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Spatial and temporal variations of phytoplankton composition and biomass in Lake Bunyonyi, South‑Western Uganda by Alex, Saturday, Thomas, J. Lyimo, John, Machiwa, Siajali, Pamba

“…The existence of some toxic phytoplankton species calls for regular monitoring and careful use of the lake and its food products.…”
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Structural tailoring of etoricoxib: A spectrochemical, medicinal and pharmacological study by Bakul Akter, Silvia Aishee, Abdullah Hridoy, Md. Mehedi Hasan Pulok, Mohammad Ariful Islam, Antu Biswas, Aurna Patwary, Majedul Hoque, MD. Sazidul Islam, Md. Nipatul Hasan Nirob, Faisal Islam Chowdhury, Monir Uzzaman

“…ADMET and PASS predictions confirmed the drug-like properties of most derivatives, particularly ETC19 and ETC9, which also showed improved absorption, better blood-brain barrier penetration, and reduced toxicity. These outcomes underscore the prospect of the de novo-designed etoricoxib analogues as safer and more effective alternatives, effectively addressing the pharmacological limitations and safety concerns associated with the parent drug.…”
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An Automatic Approach for the Identification of Offensive Language in Perso-Arabic Urdu Language: Dataset Creation and Evaluation by Salah Ud Din, Shah Khusro, Farman Ali Khan, Munir Ahmad, Oualid Ali, Taher M. Ghazal

“…With the advent of various social media platforms, offensive language usage has been widely reported, thus developing a toxic online environment that has real-life endangers within society. …”
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RSM-Based Optimization of the Parameters Affecting TiO2-Mediated UV Photocatalysis of Vehicular Emissions in Enclosed Parking Garages by Sandeep Singh, Parteek Thind, Manpreet Kaur Verma, Dapinder Deep Singh, Arjun Sareen, Dheeraj Ahuja, Jasgurpreet Singh Chohan, Raman Kumar, Shubham Sharma, Nima Khalilpoor, Alibek Issakhov

“…In the preceding times, the number of enclosed parking garages has increased significantly in developing nations. The toxic emissions from vehicular exhausts are expected to drastically compromise the environmental conditions of the parking garages. …”
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Biocompatible Heterogeneous Packaging and Laser-Assisted Fluid Interface Control for In Situ Sensor in Organ-on-a-Chip by Yu-Hsuan Lin, Shing-Fung Lau, Yen-Pei Lu, Kuo-Cheng Huang, Chien-Fang Ding, Yu-Hsiang Tang, Hsin-Yi Tsai

“…Using a kidney-on-a-chip as a case study, a non-toxic packaging process and fluid interface control methods have been successfully developed. …”
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Real-World Data for Lenvatinib in Radioiodine-Refractory Differentiated Thyroid Cancer (RELEVANT): A Retrospective Multicentric Analysis of Clinical Practice in Austria by G. Rendl, B. Sipos, A. Becherer, S. Sorko, C. Trummer, M. Raderer, W. Hitzl, M. Ardelt, H. J. Gallowitsch, C. Pirich

“…Dose reduction was noted in 39 patients (91%). Grade ≥3 toxicities (hypertension, diarrhea, weight loss, and palmar-plantar erythrodysesthesia syndrome) were most common leading to discontinuation of lenvatinib in 7 patients (16%). …”
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Multifunctional Plumeria rubra nanoparticles: Antimicrobial, antiviral, antiparasitic and anti-inflammatory activities by Bassma H. Elwakil, Mohab H. Elsabrouty, Areej Eskandrani, Keshav Raj Paudel, Esraa Abdelhamid Moneer

“…Novel natural nanomaterials are extensively investigated nowadays due to their potential biological activities and low toxicity. In the present investigation, polyvinyl alcohol was used as a green reducing agent to synthesize Plumeria rubra nanoparticles. …”
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Exploring chitin metabolite profiles and sensitivity differences in Collembola species exposed to teflubenzuron by Saúl Fernandes, Diana Ilyaskina, Matty P. Berg, Marja H. Lamoree, Pim E.G. Leonards, Cornelis A.M. van Gestel

“…This study combines traditional toxicity tests with a metabolomic approach to examine the interspecies specific sensitivity of three Collembola species — Sinella curviseta, Ceratophysella denticulata, and Folsomia candida — to teflubenzuron. …”
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Expectorant Effects of <i>Atractylodes japonica</i> Koidz. ex Kitam Root Extracts on Particulate Matter-Induced Pulmonary Injury in Mice by Junho Lee, Sana Mansoor, Jeongjun Lee, Hunsuk Chung, Young-Sam Kwon, Khawaja Muhammad Imran Bashir, Jae-Suk Choi, Sae-Kwang Ku

“…This study substantiates AJ’s role in enhancing respiratory health, emphasizing its capacity as a candidate for further development into therapeutic agents against toxic environmental exposure.…”
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Efficacy and safety of an herbal galactagogue decoction versus powdered formulation in lactating rats by Pruksa Chotitham, Suksalin Booranasubkajorn, Saracha Pattanapholkornsakul, Pravit Akarasereenont, Pinpat Tripatara

“…Both PNF decoction and powder did not exhibit subacute toxicity to the liver and kidneys in maternal rats and pups. …”
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Betulinic acid protects against ovarian impairment by decreasing F-2 toxin-induced oxidative stress and inflammation associated with the downregulation of p38 expression in mice by Li Kong, Xinyu Gao, Lijuan Zhu, Xing Lin, You Huang, Chunlin Huang, Wenjiang Yang, Yazhi Chen, Haoqiang Zhao, Jing Wu, Zhihang Yuan, Jin’e Yi

“…Subsequently, we found that 0.25 mg/kg BA played an anti-inflammatory role in the F-2 toxin-induced ovarian impairment by decreasing interleukin-1β (IL-1β), IL-6, and tumor necrosis factor-α (TNF-α) mRNA expression, as well as inhibiting p38 protein expression.These data demonstrated that BA exerts its protective effect on F-2 toxin-induced ovarian oxidative impairment and inflammation by inhibiting p38 expression, which implies a natural product-based medicine to ameliorate F-2 toxin-caused female reproductive toxicity and provides a detoxifying method for food contaminated by mycotoxin.…”
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A Cell-Based Evaluation of the Tyrosinase-Mediated Metabolic Activation of Leukoderma-Inducing Phenols, II: The Depletion of <i>Nrf2</i> Augments the Cytotoxic Effect Evoked by Tyr... by Tomoko Nishimaki-Mogami, Shosuke Ito, Kazumasa Wakamatsu, Takumi Akiyama, Norimasa Tamehiro, Norihito Shibata

“…These compounds possess a <i>p</i>-substituted phenol moiety and undergo oxidation into highly reactive and toxic <i>o</i>-quinone metabolites by tyrosinase. …”
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From botany to bedside: a review of the health benefits of Lycium barbarum as a functional food by Alois Berisha, Elena-Alexandra Alexa, Robbie Kelleher, Tao Zhang

“…This review also examines the safety profile of L. barbarum, considering its side effects, toxicity, potential contamination, and interactions with medications, emphasising the importance of balancing its health-promoting properties with cautious consumption. …”
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The anti-PD-L1/CTLA-4 bispecific antibody KN046 plus lenvatinib in advanced unresectable or metastatic hepatocellular carcinoma: a phase II trial by Da Xu, Hongwei Wang, Quan Bao, Kemin Jin, Ming Liu, Wei Liu, Xiaoluan Yan, Lijun Wang, Yanqiao Zhang, Guangyu Wang, Yue Ma, Zhigang Ma, Chunhui Zhang, Jiebing Tang, Sha Wang, Jiaohui Pang, Ting Xu, Kun Wang, Baocai Xing

“…The primary endpoints were safety, tolerability, dose-limiting toxicity (DLT), and objective response rate (ORR) according to RECIST v1.1. …”
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Separation of Inorganic Forms of Tellurium Using On-Site SPE Followed by ICP-MS or ICP-OES—The Right Solution for Water Monitoring by Katarzyna Kińska, Barbara Żelazko, Olga Gajewska, Magdalena Borowska, Monika Sadowska, Beata Krasnodębska-Ostręga

“…As both forms differ in mobility and toxicity, Te speciation should be included in water monitoring, but problems with speciation changes occurring during sampling, transport, and sample storage require the use of on-site separation of Te forms. …”
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Complexed hyaluronic acid-based nanoparticles in cancer therapy and diagnosis: Research trends by natural language processing by Abd Kakhar Umar, Patanachai K. Limpikirati, Bachtiar Rivai, Ilham Ardiansah, Sriwidodo Sriwidodo, Jittima Amie Luckanagul

“…A shift in research focuses from optimizing chemical toxicity to particular targeting tactics and precise release mechanisms is evident. …”
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Protocol for a first-in-human feasibility study of T regulatory cells (TR004) for inflammatory bowel disease using (ex vivo) Treg expansion (TRIBUTE) by Jennifer Clough, Peter Irving, A Toby Prevost, Graham M Lord, Joana Vasconcelos, James B Canavan, Beverley Rodger, D Macallan

“…The primary endpoint is defined as the occurrence of dose-limiting toxicity occurring within 5 weeks post-infusion.Ethics and dissemination The study protocol and related documents have been approved by a NHS Research Ethics Committee, the Health Research Authority and the Medicines and Healthcare products Regulatory Agency for Clinical Trial Authorisation. …”
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