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3741
Characterization of some selected macroalgae extracts and assessment of their insecticidal and genotoxicity in Culex pipiens L. mosquito larvae
Published 2025-01-01“…The larvicidal activity results revealed that J. rubens methylene chloride extract was the most toxic for C. pipiens larvae with LC50 = 9.30 ppm followed by C. sinuosa acetone extract with LC50 = 82.58 ppm after 72 h of exposure. …”
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3742
Effect of Phosphogypsum Amendment on Chemical Properties of Sodic Soils at Different Incubation Periods
Published 2022-01-01“…The application of phosphogypsum (PG) on sodic soils provides nutrients to the soil, reduces the toxic effect of Na+, and improves soil properties. …”
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3743
Biosorption of hexavalent chromium in a tannery industry wastewater using fungi species
Published 2016-03-01“…This study suggested that one could select the type of fungi species, ion concentration level, selection of treatment period, quantity of biomass to be used, and pH level of the medium, to achieve the highest reduction of any toxic metals from any contaminated water, wastewater and soil environment.…”
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3744
How do lifestyle and environmental factors influence the sperm epigenome? Effects on sperm fertilising ability, embryo development, and offspring health
Published 2025-01-01“…DNA methylation is correlated with alterations in sperm quality and the ability to fertilise oocytes, possibly via a differentially regulated MAKP81IP3 signalling pathway. Paternal exposure to toxic endocrine-disrupting chemicals (EDCs) is also linked to the transgenerational transmission of increased predisposition to disease, infertility, testicular disorders, obesity, and polycystic ovarian syndrome (PCOS) in females through epigenetic changes during gametogenesis. …”
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3745
A wireless sensor network for coal mine safety powered by modified localization algorithm
Published 2025-01-01“…In coal mines, gas leaks pose a serious safety risk, often leading to explosions or toxic exposure. Temperature control is difficult due to fluctuating underground conditions, potentially causing heat stress or equipment malfunction. …”
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3746
Design of pH-Responsive Nanomaterials Based on the Tumor Microenvironment
Published 2025-01-01“…These materials trigger drug release upon reaching the tumor microenvironment, enhancing therapeutic targeting and reducing toxicity to healthy cells. pH-responsive nanomaterials include organic nanomaterials, inorganic nanomaterials, and composite nanomaterials. …”
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3747
Autologous Blood Transfusion after Local Infiltration Analgesia with Ropivacaine in Total Knee and Hip Arthroplasty
Published 2012-01-01“…All concentrations observed were below the threshold for toxicity and no side effects were observed. Conclusion. …”
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3748
The Role of Quercetin, a Flavonoid in the Management of Pathogenesis Through Regulation of Oxidative Stress, Inflammation, and Biological Activities
Published 2025-01-01“…Furthermore, more research based on nanoformulations should be performed to minimize/overcome the hindrance associated with bioavailability, rapid degradation, and toxicity.…”
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3749
Simultaneous Quantification of Dexpanthenol and Resorcinol from Hair Care Formulation Using Liquid Chromatography: Method Development and Validation
Published 2016-01-01“…On the other hand resorcinol is mainly prescribed for the treatment of seborrheic dermatitis of scalp. The toxic side effects of resorcinol limit its use in dermatological preparations. …”
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3750
Hepatoprotective Effects of Crude Stem Bark Extracts and Solvent Fractions of Cordia africana against Acetaminophen-Induced Liver Injury in Rats
Published 2022-01-01“…Thus, this study aimed to investigate the hepatoprotective effects of an aqueous (CAAE), 80% methanol extracts of C. africana stem bark (CAME), and the solvent fractions of the methanol extract against acetaminophen (APAP)-induced liver injury in rats. Acute toxicity test and APAP-induced lethality test were done on mice of either sex, while APAP dose selection test was done on female rats. …”
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3751
Isotherms and Kinetic Studies of Copper Removal from Textile Wastewater and Aqueous Solution Using Powdered Banana Peel Waste as an Adsorbent in Batch Adsorption Systems
Published 2023-01-01“…Heavy metals that are present in surface water and wastewater are becoming a severe environmental problem. Because of its toxicity, heavy metal removal has become the main priority for environmental concerns. …”
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3752
Single-center experience of venetoclax combined with azacitidine in young patients with newly diagnosed acute myeloid leukemia
Published 2025-01-01“…Conclusion: In conclusion, our study indicated that VEN + AZA with a higher MRD-negative remission rate and less toxic appeared to be a therapy option for young patients with ND AML. …”
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3753
Sophocarpine inhibits the proliferation and induces apoptosis of glioblastoma cells through regulating the miR-21/PTEN/PI3K/AKT axis
Published 2025-02-01“…CCK-8 was applied to analyze cell toxicity and proliferation. qRT-PCR and western blot were used to measure RNA and protein expressions, respectively. …”
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3754
Drug Target Investigation of <i>N</i>-<i>p</i>-Coumaroyl-<i>N</i>’-Caffeoylputrescine, a Naturally-Occurring Alkaloid Derived from <i>Saxifraga tangutica</i>
Published 2024-12-01“…Furthermore, a prediction of the absorption, distribution, metabolism, excretion, and toxicity was also applied to evaluate the drug-like properties of PCC. …”
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3755
Biological Evaluation of Platinum(II) Sulfonamido Complexes: Synthesis, Characterization, Cytotoxicity, and Biological Imaging
Published 2022-01-01“…L1 displays intense fluorescence from the 1LC excited state, while C1 gives phosphorescence from the 3LC state. Mammalian cell toxicity of ligands and complexes was assessed with NCI–H292 nonsmall-cell lung cancer cells. …”
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3756
Mesenchymal Stromal Cells Mediate Clinically Unpromising but Favourable Immune Responses in Kidney Transplant Patients
Published 2022-01-01“…Patients displayed no signs of discomfort or dose-related toxicities in response to MSC infusion. Flow cytometric analysis revealed an increase in B regulatory lymphocyte populations and nonconventional T regulatory cells and a decrease in T effector lymphocyte proportions in auto-MSC-infused patients. …”
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3757
CD73/adenosine dynamics in treatment-induced pneumonitis: balancing efficacy with risks of adverse events in combined radio-immunotherapies
Published 2025-01-01“…In fact, combined radio-immunotherapies bear an increased risk of irAEs in the lungs, and additional pharmacologic inhibition of CD73 may further enhance the risk of overwhelming or overlapping pulmonary toxicity and thereby limit therapy outcome. This review explores how therapeutic interventions targeting CD73/adenosine dynamics could enhance radiation-induced immune activation in combined radio-immunotherapies, whilst potentially driving irAEs in the lung. …”
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3758
Additive Effects of Glutathione in Improving Antibiotic Efficacy in HIV–<i>M.tb</i> Co-Infection in the Central Nervous System: A Systematic Review
Published 2025-01-01“…N-acetylcysteine (NAC), a GSH precursor, was shown to significantly enhance the efficacy of first-line TB antibiotics and mitigate treatment-associated toxicity. Discussion: GSH shows promise as an adjunct therapy for HIV–<i>M.tb</i> co-infection, particularly for cases involving the CNS, where it may improve immune recovery and reduce inflammation. …”
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3759
Environmental consequences of oil and gas extraction on the example of the Bytkiv-Babchenskyi Oil and Gas Field
Published 2024-12-01“…The determined chemical, physico-chemical indicators of water quality, the content of volatile organic compounds and polyaromatic hydrocarbons complied with the regulatory standards. Among the toxic elements, strontium was detected, the content of which did not exceed the maximum permissible concentration. …”
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3760
Genetic markers for the resistance of honey bee to Varroa destructor
Published 2020-12-01“…The use of synthetic acaricides has not justified itself – they make beekeeping products unsuitable and mites develop resistance to them, which forces the use of even greater concentrations that can be toxic to the bees. Therefore, the only safe measure to combat the mite is the use of biological control methods. …”
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