Respirable Particles and Gas Contaminants Emissions from a Desktop Laser Cutter and Engraver by Kevin O’Neill, Xinyi Niu, Jun Wang, Runcheng Fang

“…These contaminants include respirable particulates, volatile organic compounds (VOCs), and other toxic substances that pose health risks to humans. …”
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Structural, Optical, Antibacterial, and Anticancer Properties of Cerium Oxide Nanoparticles Prepared by Green Synthesis Using Morinda citrifolia Leaves Extract by Abozer Y. Elderdery, Badr Alzahrani, Abdulrahim A. Alabdulsalam, Siddiqa M. A. Hamza, Ahmed M. E. Elkhalifa, Abdulaziz H. Alhamidi, Fehaid Alanazi, A. Mohamedain, Suresh Kumar Subbiah, Pooi Ling Mok

“…Green synthesis of nanoparticles is preferred to make it more economical, eco-friendly, and less toxic. The aim of our study here is to formulate the CeO2 NPs (CeO2 NPs) using Morinda citrifolia (Noni) leaf extract and study its optical, structural, antibacterial, and anticancer abilities. …”
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Antifungal Effect of Cinnamon Bark Extract on the Phytopathogenic Fungus Fusarium sporotrichioides by Katarina Martinko, Eni Mioč

“…The focus of interest is therefore finding plant extracts that have antifungal properties and are not toxic to organisms, so that they can be used for the biological control of economically important phytopathogenic fungi such as Fusarium. …”
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Biomonitoring potential of trace metal accumulation and bioavailability in coral skeletons and reef sediments of Persian Gulf: A comparative study by Seyed Hassan Mousavi, Mehdi Gholamalifard, Seyed Mahmoud Ghasempouri

“…According to the sediment pollution indices, Site I showed the highest potential toxicity to biota, followed by Site II and then Site III. …”
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Ca–Mg-Doped Surface-Modified Nano-Sized Ferrihydrite Powder Synthesized by Surfactant Mediation–Precipitation Technique: A Novel Super Adsorbent for Cations by M. Mohapatra, T. Padhi, S. Anand, B.K. Mishra

“…Although Cu(II)- or Co(II)-loaded adsorbents could not be regenerated, toxicity characteristic leaching procedure tests confirmed that they were safe for disposal. …”
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A Rare Case of Large-Vessel Vasculitis following Checkpoint Inhibitor Therapy and Pegfilgrastim by Joseph Mort, Shipra Maheshwari, Nayanika Basu, Patrick Dillon, Kevin Brady, Harry Bear, Trish Millard

“…Immune-related adverse events (irAEs) such as colitis and pneumonitis are well-established toxicities associated with CPI therapy. However, large-vessel vasculitis secondary to CPI utilization is reported only in rare case reports and case series. …”
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Suppression of IRE1α Attenuated the Fatty Degeneration in Parenteral Nutrition-Related Liver Disease (PNALD) Cell Model by Ningxun Cui, Mingling Cui, Jie Li, Xueping Zhu, Xiaoli Zhu

“…The results of Oil Red O staining indicated that the PNALD was successfully established in BRL cells and the CCK-8 data indicated which 0.6% that SO was further applied to the experiment owing to its better induction of PNALD and less toxicity to the cells. Besides, the value of biochemical parameters (TBIL, DBIL, ALT, and AST) was also elevated in the SO group compared with the NG group. …”
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Nanoparticles assisted drug delivery for effective management of Glioblastoma by Mansi Damani, Nagesh Nilawar, Munira Momin, Raghumani Singh Ningthoujham, Tabassum Khan

“…Due to their size, surface modifications, and capability to encapsulate drugs, nanocarriers like polymeric, metallic, and lipid nanoparticles have shown potential in enhancing the penetration of anticancer agents across the BBB and BBTB, thus increasing treatment efficacy and minimizing general toxicity. Moreover, lipid-based nanoparticles, such as solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs), offer advantages in drug encapsulation, stability, and controlled release metal nanoparticles, including gold and silver nanoparticles, provide unique properties for imaging and photothermal therapy, potentially augmenting the efficacy of conventional treatments. …”
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Hiper IgE dengan Nekrolisis Epidermal Toksik by Adrian Ramdhany, Raveinal Raveinal

“…Akibatnya, istilah-istilah seperti ‘staphylococcal-induced toxic epidermal necrolysis’ dan ‘drug-induced scalded skin syndrome’ menang selama beberapa dekade, tetapi sekarang dipisahkan karena terapi dan prognosisnya berbeda. …”
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Safety, Tolerability, and Pharmacokinetics of NIM‐1324 an Oral LANCL2 Agonist in a Randomized, Double‐Blind, Placebo‐Controlled Phase I Clinical Trial by Andrew Leber, Raquel Hontecillas, Nuria Tubau‐Juni, Josep Bassaganya‐Riera

“…In conclusion, NIM‐1324 treatment is well‐tolerated up to daily oral doses of at least 1500 mg (nominal), a ≥ six‐fold margin over the anticipated therapeutic dose, and 1000 mg (maximum observed exposure), at least a four‐fold margin over the anticipated therapeutic dose with no dose limiting toxicities.…”
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Research Progress of Common Rehabilitation Training Methods in Mild Cognitive Impairment by WANG Yiyuan, FAN Chenyu, WANG Nianhong, WU Yi

“…Drug treatment is now the primary approach for MCI, but long-term drug treatment can lead to strong addictive tendencies and produce toxic side effects. Therefore, it is extremely urgent to explore effective rehabilitation training methods. …”
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Machine learning insights into early mortality risks for small cell lung cancer patients post-chemotherapy by Min Liang, Min Liang, Fuyuan Luo

“…However, the treatment is associated with significant risks, including heightened toxicity and early mortality. This study aimed to quantify the 90-day mortality rate post-chemotherapy in SCLC patients, identify associated features, and develop a predictive machine learning model.MethodsThis study utilized data from the Surveillance, Epidemiology, and End Results (SEER) database (2000–2018) to identify prognostic features influencing early mortality in SCLC patients. …”
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Characterization of Patients with Acute Myocardial Infarction Treated at the General University Hospital Dr. Gustavo Aldereguía Lima by Edislaimy Suárez Rosales, Rodolfo Javier Rivero Morey, Lourdes María Roca Surí, Francisco de Jesús Valladares Carvajal, Evelyn Delgado Rodríguez, Lourdes María Fernández García

“…Variables such as: age, sex, skin color, origin, comorbidities, toxic habits, clinical manifestations, thrombolysis, place where they were thrombolyzed, causes of non-thrombolysis, topography of acute myocardial infarction, discharge status, infarction complications and of thrombolytic treatment. …”
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Examination of common culture medium for human hepatocytes and engineered heart tissue: Towards an evaluation of cardiotoxicity associated with hepatic drug metabolism in vitro. by Shinichiro Horiuchi, Nanae Koda, Yui Ikeda, Yuto Tanaka, Yusuke Masuo, Yukio Kato, Daiju Yamazaki

“…Cardiotoxicity associated with hepatic metabolism and drug-drug interactions is a serious concern. Predicting drug toxicity using animals remains challenging due to species and ethical concerns, necessitating the need to develop alternative approaches. …”
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Curcumin as a potential inhibitor of TGFβ3 computational insights for breast cancer therapy by Ali G. Alkhathami, Mohammad Y. Alshahrani, Saad Ali Alshehri, Nazim Nasir, Shadma Wahab

“…The curcumin has low Molecular Weight 368.130 (MW) and follows Lipinski Rule, Pfizer Rule, GSK Rule, Golden Triangle, BMS Rule, zero PAINS alert and Acute Toxicity Rule with zero alert. Any drug-like contender must follow these qualities. …”
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Modeling of genetic processes underlying the development of resistance to fipronil in the Colorado potato beetle (Leptinotarsa decemlineata Say) by K. A. Kitaev, I. S. Mardanshin, E. V. Surina, T. I. Leontieva, M. B. Udalov, G. V. Benkovskaya

“…Calculations of the survival rates of Colorado potato beetle individuals were carried out taking into account the statistical regularities of the distribution of the toxic substance after treatment by insecticides. …”
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Immunoinformatics Approach to Design a Chimeric CD70-Peptide Vaccine against Renal Cell Carcinoma by Haideh Namdari, Farhad Rezaei, Fatemeh Heidarnejad, Mohammad Yaghoubzad-Maleki, Maryam Karamigolbaghi

“…Computational assessments were performed on these chimeric vaccines for antigenicity, allergenicity, peptide toxicity, population coverage, and physicochemical properties. …”
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Ambient fine particulate matter provokes multiple modalities of cell death via perturbation of subcellular structures by Yán Wāng

“…The mechanisms of PM2.5 toxicity, encompassing oxidative stress, inflammatory responses, and metabolic imbalances, are described in detail. …”
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Re‐evaluation of butane (E 943a), isobutane (E 943b) and propane (E 944) as food additives by EFSA Panel on Food Additives and Flavourings (FAF), Laurence Castle, Monica Andreassen, Gabriele Aquilina, Maria Bastos, Polly Boon, Biagio Fallico, Reginald Fitzgerald, Maria Jose Frutos Fernandez, Bettina Grasl‐Kraupp, Ursula Gundert‐Remy, Rainer Gürtler, Eric Houdeau, Marcin Kurek, Henriqueta Louro, Patricia Morales, Sabina Passamonti, Gabriele Gagliardi, Salvatore Multari, Josef Daniel Rasinger, Ana Maria Rincon, Camilla Smeraldi

“…Existing EU specifications for the three food additives already contain limits for the toxic impurity 1,3‐butadiene (1,3‐BD), however due to a lack of information on the manufacturing processes used, uncertainties do remain regarding the potential presence of other impurities not listed in the current EU specifications for food additives. …”
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A randomized controlled trial: Effects of compression therapy combined with exercise on chemotherapy-induced peripheral neuropathy in patients with breast cancer by Yu Xiaoqian, Hu Jiwei, Zhou Lizhi, Guo Baojia, Guo Luyan, Xu Huiqian, Li Hong, Fan Yijing

“…The National Institute of Cancer Drug Toxicity Rating Scale and the Chemotherapy-Induced Peripheral Neuropathy Assessment Tool were assessed and compared between groups. …”
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