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3661
How to get over with medication errors underestimation? Improving indices of medication errors with focus on intravenous medications in hematopoietic stem cell transplantation sett...
Published 2024-01-01“…Especially, in the hematopoietic stem cell transplantation (HSCT) setting where toxic drugs are frequently used and patients are in critical immunocompromised conditions, medication errors (ME) can have catastrophic reactions and devastating outcomes such as death. …”
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3662
Assessing the Efficacy of Gelatin Composite 3D Scaffolds in Cardiovascular Tissue Engineering: An In Vitro Study
Published 2024-04-01“…Biological evaluation demonstrated satisfactory cell adhesion, biocompatibility, and absence of toxicity in the 3D-printed scaffolds. However, altering the printing angle could modify biological properties due to changes in scaffold characteristics. …”
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3663
Human Islet Amyloid Polypeptide Fibril Binding to Catalase: A Transmission Electron Microscopy and Microplate Study
Published 2010-01-01“…Human IAPP fibrils are toxic in a similar manner to Alzheimer's amyloid-β (Aβ) and prion protein (PrP) fibrils. …”
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3664
Advancements in Liposomal Nanomedicines: Innovative Formulations, Therapeutic Applications, and Future Directions in Precision Medicine
Published 2025-01-01“…The recent COVID-19 pandemic has accelerated research in liposomal-based vaccines and antiviral therapies, underscoring the need for improved delivery mechanisms to overcome challenges like rapid clearance and organ toxicity. Furthermore, we discuss the potential of “smart” liposomes, which can respond to specific disease microenvironments, enhancing treatment efficacy and precision. …”
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3665
Application of central composite design to optimization of Yellow Tartarazine and Methylene Blue environmentally clean adsorption by untreated walnut shells
Published 2024-10-01“…Climate change poses a real threat to the water security by altering the precipitation patterns and other weather variables, desirability function (df) was used to determine the interactive effects and optimize with the Central Composite Design (CCD) of important variables such as initial dyes concentration (C o : 20–100 mg L –1 ), solution pH (1.5–11), temperature (20–60 °C) and adsorbent dosage (0.1–1.3 g L –1 ) for the removal of toxic Yellow Tartarazine (YT) and Methylene Blue (MB) onto Untreated Walnut Shells (UWS). …”
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3666
Experience in the management of patients with HTLV-1 positive adult T-cell leukemia/lymphoma in a Latin American center
Published 2025-02-01“…However, the overall response rate to chemotherapy was low, and most patients experienced complications and toxicities associated with treatment. Conclusion: This study provides insights into the clinical course and management of ATL in a Colombian population. …”
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3667
Delayed Acetaminophen Absorption Resulting in Acute Liver Failure
Published 2022-01-01“…Acetaminophen metabolites were measured, including nontoxic glucuronide and sulfate conjugates and toxic cytochrome P450 (CYP) metabolites. The metabolite data demonstrated increasing CYP metabolites in occurrence with the delayed acetaminophen peak concentration. …”
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3668
Release of apoptosis inhibitor of macrophage (AIM) from pentameric IgM in serum predicts prognosis after hemodialysis initiation
Published 2025-01-01“…Patients at dialysis initiation with high proportion of serum IgM-free AIM (fAIM%) show elevated uremic toxins and other toxic metabolites, higher mortality, and increased cardiovascular risk compared to those with low fAIM%. …”
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3669
Chitooligosaccharides suppress airway inflammation, fibrosis, and mucus hypersecretion in a house dust mite-induced allergy model
Published 2025-01-01“…Chitooligosaccharides (COS) are known for their antioxidant and anti-inflammatory properties.MethodsHuman airway epithelial cells (BEAS-2B) were cultured in DMEM/F12 medium containing COS at concentrations of 25–100 µg/ml for 24 h. No intracellular toxicity was observed up to 1,000 µg/ml. Cell experiments were conducted at COS concentrations below 100 µg/ml, while animal experiments were performed at concentrations below 100 mg/kg body weight for 4 weeks. …”
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3670
RELATIONSHIP BETWEEN ADSORPTION-RHEOLOGICAL PROPERTIES OF SERUM IN HEMORRHAGIC VASCULITIS AND ECOLOGY IN REGIONS OF PATIENTS’ RESIDENCE
Published 2017-03-01“…Adsorption-rheological properties of serum of patients with HV depend on the integrated degree of pollution by xenobiotics of air and drinking water (but not of soil by chemical elements), the degree of emissions and accumulation of industrial waste in it, the nature of the impact of modernization of agriculture, metallurgical, chemical and engineering industries in the regions, levels of 3,4-benzpyrene (ST2, PA), phenol (BV, PA), ammonia (SCIA), nitrogen dioxide (ST1, ST2, ST3), carbon dioxide (SE, RT, ST1, ST2, ST4) in the breathing air, the degree of mineralization and hardness of drinking water (MV), the parameters of toxic microelements and essential zinc (ST3) in the soil. …”
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3671
The use of Kutikulin for treatment and prevention of gastrointestinal diseases in calves and piglets
Published 2022-06-01“…The paper presents the results of tests of Kutikulin, a product made at the Vologda Branch of the FSC VIEV, which consists of chicken gizzard cuticle containing a keratoid secretion and a number of biologically active enzymes. It is a non-toxic, water-insoluble, odourless yellow-green powder with a bitterish taste. …”
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3672
Evaluation of the Acute Hepatoprotective Potential of Hydroethanolic Extract of Duranta erecta L. Parts
Published 2020-01-01“…The findings suggest that hydroethanolic Duranta erecta ripe fruits extract possesses hepatoprotective and antioxidative activities against CCl4- and acetaminophen-induced toxicity and could be developed as a potent agent for drug-induced liver diseases.…”
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3673
Fabrication of composite ceramic polymeric membranes for agricultural wastewater treatment
Published 2025-01-01“…The study examined how effectively the membranes removed toxic substances from wastewater. The findings exhibited an excellent removal of > 80% and up to 97.02%, > 80% and up to 99.97% of the heavy metals, and optimum fluxes of 341.07 and 276.35 L h−1 m−2 were achieved in the cases of M2 and M4, respectively. …”
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3674
Evaluation of Toxicological Risks and Effects of Microplastics on Nile Tilapia (Oreochromisniloticus) under in Vitro Laboratory Conditions
Published 2023-12-01“…The objective of research was to determine the toxicity of microplastics to Nile tilapia (Oreochromis niloticus). …”
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3675
Clove oil as a neuromodulator in environmental cadmium cognitive impairment on the prefrontal cortex of Wistar rats
Published 2025-03-01“…Conclusion: Clove oil alleviates cadmium toxicity by increasing antioxidant activity and improving cognition in rats.…”
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3676
Surface hardening of MIM porous metals by ultrasonic vibration assisted pressing
Published 2025-01-01“…This surface strengthening method uses an ultrasonically vibrating punch to work-harden the surface, enabling localised hardening in a short time without using highly toxic chemicals or large-scale equipment. In addition, porous metals have the properties of absorbing sound and shock, which allows them to efficiently absorb the energy of ultrasonic vibrations and effectively harden the surface. …”
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3677
Metabolomic profiling reveals systemic metabolic disruptions induced by combined exposure to particulate matter and ozone
Published 2025-01-01“…In conclusion, this study provides new insights into the systemic metabolic effects of air pollutant exposure, identifies novel metabolic targets of pollutant-induced toxicity, highlights the complex interactions resulting from combined exposure to multiple pollutants, and underscores the importance of assessing the combined effects of multiple pollutants in air pollution risk assessments.…”
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3678
Cyanin Chloride Inhibits Hyperbaric Pressure-Induced Decrease of Intracellular Glutamate-Aspartate Transporter in Rat Retinal Müller Cells
Published 2018-01-01“…High concentrations of extracellular glutamate are toxic to the optic nerve. The glutamate-aspartate transporter (GLAST) in retinal Müller cells is involved in the development of glaucoma. …”
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3679
Local control and recurrence patterns after stereotactic irradiation delivered in more than 4 fractions for hepatocellular carcinomas and liver metastases: a retrospective study
Published 2025-02-01“…Conclusion Despite dose reductions to spare OAR, SBRT showed satisfactory LC with low toxicity. Out-of-field recurrence remains the most common pattern identified and likely related to underlying disease. …”
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3680
High antimony resistance strain Enterobacter sp. Z1 mediates biomineralization of antimony trioxide
Published 2025-01-01“…The increasing antimony (Sb) contamination prevalence poses a concern owing to its toxicity and potential carcinogenic properties. However, mechanisms underlying the microbial conversion of soluble Sb into insoluble Sb minerals remain unclear. …”
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