Gastrointestinal Bleeding and Diffuse Skin Thickening as Kaposi Sarcoma Clinical Presentation by Sara Querido, Henrique Silva Sousa, Tiago Assis Pereira, Rita Birne, Patrícia Matias, Cristina Jorge, André Weigert, Teresa Adragão, Margarida Bruges, Domingos Machado

“…A renal allograft biopsy revealed interstitial fibrosis and tubular atrophy grade II. Toxicity of calcineurin inhibitor was assumed and, after a switch for everolimus, renal function improved. …”
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Investigating Feasibility of C. I. direct Yellow 50 dye Degradation and Detoxicification in Synthetic Aquatic Solution Effluent by UVA/TiO2 Nanophotocatalytic process using Daphnia... by Feizollah Dinarvand, Nematollah Jaafarzadeh, Mehdi Ahmadi Moghadam, Mohammad Bagher Miranzadeh, Nezam Mirzaei

“…Introduction and Aims: Compounds containing dye are toxic, carcinogenic and mutagenic for aquatic organisms and lead to mutagenicity, carcinogenicity, and dysfunction of human beings’ kidney, liver, brain, reproductive system and central nervous system. …”
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Veterinary Drug Residues in Food Products of Animal Origin and Their Public Health Consequences: A Review by Yeshambel Muluye Mesfin, Birhan Agmas Mitiku, Habtamu Tamrat Admasu

“…The use of veterinary products above or below the advised level may also result in short‐ or long‐term public health issues, such as the creation of resistant strains of micro‐organisms, toxicity, allergy, mutagenesis, teratogenicity and carcinogenetic effects. …”
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Identification and pharmacokinetics of saponins in Rhizoma Anemarrhenae after oral administration to rats by HPLC-Q-TOF/MS and HPLC-MS/MS by Wang Hai-Qiao, Lan Fen, Zhang Yi-Han, Xia Jin-Er, Gong Xiao-Mei, Liu Min

“…It is essential to classify the properties of saponins which are associated with their toxicity and efficacy. In this study, 25 compounds were identified by HPLC-Q-TOF/MS in the extract of Rhizoma Anemarrhenae and 8 saponins were detected in rat plasma by HPLC-MS/MS after oral administration of this extract. …”
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Cytotoxicity and Induction of Inflammation by Pepsin in Acid in Bronchial Epithelial Cells by Erik Bathoorn, Paul Daly, Birgit Gaiser, Karl Sternad, Craig Poland, William MacNee, Ellen M. Drost

“…Aspiration of gastric fluids may cause damage to airway epithelial cells, not only because acidity is toxic to bronchial epithelial cells, but also since it contains digestive enzymes, such as pepsin. …”
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Increased Anti-Proliferation Performance of NanoChitosan-Moringa Seeds Extract and Co-Treatment with Doxorubicin in Liver Cancer Cells by Hendra Susanto, Moch Sholeh, Agustina Tri Endharti, Nik Ahmad Nizam Nik Malek, Sa’diyatul Rizqie Amaliyah Firdaus, Adeodatus Yuda Handaya, Ahmad Taufiq

“…In conclusion, NCH-Mosee with dose-tracking toxicity combined with Dox can suppress the viability of Hep G2 cells. …”
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TClC effectively suppresses the growth and metastasis of NSCLC via polypharmacology by Jing Lu, Ying Zhang, Chunyan Yan, Jingwen Liu, Dan Qi, Yue Zhou, Qinwen Wang, Juechen Yang, Jing Jiang, Benhao Wu, Meiling Yang, Weiwei Zhang, Xin Zhang, Xiaoyu Shi, Yan Zhang, Kun Liu, Yongcai Liang, Chaoyang Wang, Hanyu Yang, Yuqing Gao, Yuping Sun, Ronghu Ke, Jason H. Huang, Min Wu, Hongbo Wang, Chunlei Li, Shuang Zhou, Bin Guo, Erxi Wu, Guoying Zhang

“…In response, we synthesized a novel bioactive compound, ethyl 6-chlorocoumarin-3-carboxylyl L-theanine (TClC), which significantly inhibited NSCLC growth, epithelial mesenchymal transition (EMT), migration, and invasion in vitro and tumor growth and metastasis in vivo without inducing toxicity. TClC disrupts autocrine loops that promote tumor progression, particularly in stem-like CD133-positive NSCLC (CD133+ LC) cells, which are pivotal in tumor metastasis. …”
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Chemical Characterization of Specific Micropollutants from Textile Industry Effluents in Fez City, Morocco by Hakima Talouizte, Mohammed Merzouki, Mohammed Benlemlih, Mohammed Bendriss Amraoui

“…In this work, characterization of toxic organic compounds is proposed. Based on gas chromatography coupled to mass spectrometry (GC/MS) screening analysis, organic micropollutant diversity of textile effluents from a local textile processing factory was investigated. …”
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Cost‐Effective Synthesis of Fe5C2 Catalyst From Nanosized Zero‐Valent Iron to Achieve Efficient Photothermocatalytic CO Hydrogenation to Light Olefins by Yuqing Xu, Yuan Li, Ruizhe Li, Hua Xu, Shuxin Ouyang, Hong Yuan

“…However, iron carbonyls, the raw materials for wet chemical synthesis of Fe5C2, are expensive and toxic, which limits large‐scale preparation. Here, a cost‐effective and versatile method is proposed for the synthesis of Fe5C2 nanoparticles (NPs) with nanosized zero‐valent iron (abbreviated as NZVI, prepared by reducing iron salts or ball‐milling iron powder) instead of iron carbonyls, achieving a cost reduction of 76.8%. …”
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Comprehensive analysis of proteomic and biochemical responses of Daphnia magna to short-term exposure to polystyrene microplastic particles by Young Sang Kwon, Chang-Beom Park, Seung-Min Lee, Jin-Woo Park, Yeong-Jin Kim, Jong-Hwan Kim, Jong-Su Seo

“…This study emphasizes the urgency of understanding MP toxicity to guide environmental policies and conservation efforts aimed at mitigating the effects of plastic pollution.…”
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Identification of hydrochemical processes and assessment of groundwater quality: a case study of the intergranular aquifer in Dili City, Timor-Leste by Marçal Ximenes, João A. M. S. Pratas, José M. M. De Azevedo, Fernando. P. O. O. Figueiredo, Mattew Currell

“…The analysis focuses on major and minor ions (Ca²⁺, Mg²⁺, Na⁺, K⁺, SO₄²⁻, HCO₃⁻, F⁻), physicochemical parameters (pH, electrical conductivity, total dissolved solids), and toxic elements (Mn, Fe, Pb, Al, As, Zn, Cd, Ni). …”
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Reduction and Health Risk Assessment of Imidacloprid Insecticide Residues in Grapes Using Home Washing Methods by Parvaneh Shayanrad, Nasrin Hassanzadeh

“…This study aims to assess the effectiveness of non-toxic household methods in reducing imidacloprid residues on grapes. …”
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Theranostic Contact Lens for Ocular Cystinosis Utilizing Gold Nanoparticles by Eunbe Ha, Hwajeong Kang, Hyeran Noh

“…The current treatment involves frequent administration of cysteamine eye drops, which suffer from low bioavailability and can lead to drug toxicity, making it essential to prescribe an appropriate dosage based on the patient’s condition. …”
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Advances in Pure Drug Self-Assembled Nanosystems: A Novel Strategy for Combined Cancer Therapy by Runyan Niu, Xuexue Liu, Xian Yang, Xiao Du, Siliang Wang, Xiaolong Ma, Shaoping Yin, Lihua Shao, Jinping Zhang

“…However, their clinical translation remains hindered by several significant challenges, including intricate preparation processes, limited drug loading capacity, and concerns regarding potential toxicity. In this context, pure drug-assembled nanosystems (PDANSs) have emerged as a promising alternative, attracting extensive research interest due to their simple preparation methods, high drug loading efficiency, and suitability for large-scale industrial production. …”
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Enhancing the Therapeutic Potential of Peptide Antibiotics Using Bacteriophage Mimicry Strategies by Hongping Wan, Xinyi Zhong, Shinong Yang, Jiarong Deng, Xu Song, Yong Liu, Yuanfeng Li, Zhongqiong Yin, Xinghong Zhao

“…Notably, they significantly reduce the acute toxicity of nisin, rendering it suitable for intravenous administration. …”
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A Review on Synthesis and Characterization of Ag2O Nanoparticles for Photocatalytic Applications by Workneh M. Shume, H. C. Ananda Murthy, Enyew Amare Zereffa

“…Even though the photocatalytic processes are a good technology for treatment of toxic organic pollutants, the majority of current photocatalysts cannot utilize sunlight sufficiently to realize the decomposition of these organic pollutants. …”
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Research progress on modification of hemodialysis membranes with anticoagulant properties by Xuan WANG, Zehua LI, Runjie SHI, Tiantian LI, Ruolin WANG, Chunmei NIU

“…The dialysis membrane is the most important component of hemodialyzer, and its performance depends on the feasibility and biocompatibility of removing toxic solutes. However, when the membrane material is in contact with blood directly, plasma proteins will quickly adsorb on the surface of the membrane and bind to the glycoprotein receptors on platelets, resulting in platelet activation, coagulation cascade and complement activation. …”
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Opposing roles of p38α-mediated phosphorylation and PRMT1-mediated arginine methylation in driving TDP-43 proteinopathy by Mari Aikio, Hana M. Odeh, Heike J. Wobst, Bo Lim Lee, Úna Chan, Jocelyn C. Mauna, Korrie L. Mack, Bradley Class, Thomas A. Ollerhead, Alice F. Ford, Edward M. Barbieri, Ryan R. Cupo, Lauren E. Drake, Joshua L. Smalley, Yuan-Ta Lin, Stephanie Lam, Reuben Thomas, Nicholas Castello, Ashmita Baral, Jenna N. Beyer, Mohd A. Najar, John Dunlop, Aaron D. Gitler, Ashkan Javaherian, Julia A. Kaye, George M. Burslem, Dean G. Brown, Christopher J. Donnelly, Steven Finkbeiner, Stephen J. Moss, Nicholas J. Brandon, James Shorter

“…The mechanisms underlying toxic TDP-43 accumulation are not understood. Persistent activation of p38 mitogen-activated protein kinase (MAPK) is implicated in ALS. …”
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Photodynamic therapy for the precise treatment of localized prostate cancer by Youcheng Xu, Qinyuan Tan, Chong Sun, Yuefeng Jia, Shengxian Li, Xuecheng Yang

“…In contrast, photodynamic therapy (PDT) is introduced into the treatment of prostate cancer because of its advantages, such as high precision to tumor cells, low toxicity, and no radiation. Compared to radical prostatectomy, the PDT has low risk and minimal trauma. …”
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Functional analysis of the type II toxin-antitoxin system ParDE in Streptococcus suis serotype 2 by Qibing Gu, Xiayu Zhu, Jiale Ma, Tao Jiang, Zihao Pan, Huochun Yao

“…We constructed a mutant strain, ΔparDE, to explore its functions in bacterial virulence, various stress responses, and biofilm formation capabilities. The toxicity exerted by the toxin ParE can be neutralized by the antitoxin ParD. …”
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