Fabrication of a Porous Metal-Organic Framework with Polar Channels for 5-Fu Delivery and Inhibiting Human Osteosarcoma Cells by Li-Chun Zhao, Mei Tang, Qian-Hua Zhang, Zhi-Yi Hu, Hong-Wei Gao, Xia-Yun Liao, Gang Wang, Jing Leng

“…Furthermore, as indicated by the MTT assay, this drug/MOF composite shows low toxicity toward the human normal cells and demonstrates obvious anticancer activity against the human osteosarcoma cell line MG63.…”
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Safety evaluation of the food enzym endo‐1,4‐β‐xylanase from the genetically modified Bacillus subtilis strain AR‐153 by EFSA Panel on Food Enzymes (FEZ), Holger Zorn, José Manuel Barat Baviera, Claudia Bolognesi, Francesco Catania, Gabriele Gadermaier, Ralf Greiner, Baltasar Mayo, Alicja Mortensen, Yrjö Henrik Roos, Marize L. M. Solano, Monika Sramkova, Henk Van Loveren, Laurence Vernis, Jaime Aguilera, Giulio diPiazza, Yi Liu

“…Given the QPS status of the production strain and the absence of concerns resulting from the food enzyme manufacturing process, toxicity tests were considered unnecessary by the Panel. …”
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Protective Effect of Vitamins C and E on Depot-Medroxyprogesterone Acetate-Induced Ovarian Oxidative Stress In Vivo by Atik Ismiyati, I. Wayan Arsana Wiyasa, Dwi Yuni Nur Hidayati

“…Therefore, this may provide an antioxidant therapy for attenuating the ovarian toxicity found in the DMPA therapy.…”
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Traditional knowledge, uses, and perceptions of mushrooms among the Wixaritari and mestizos of Villa Guerrero, Jalisco, Mexico by Mara Ximena Haro-Luna, Felipe Ruan-Soto, Laura Guzmán-Dávalos

“…In addition, the Wixaritari were found to associate toxic mushrooms with the divine, as evidenced by one case of the use of mushrooms as a hierophanic agent. …”
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A Numerical Approach to Analysis of an Environment-Friendly Sn-Based Perovskite Solar Cell with SnO2 Buffer Layer Using SCAPS-1D by Sunirmal Kumar Biswas, Md. Shamsujjoha Sumon, Kushal Sarker, Mst. Farzana Orthe, Md. Mostak Ahmed

“…The main aim of this study is to develop an environment-friendly and highly efficient structure that can be used as an alternative to other toxic lead-based perovskite solar cells. This work performed a numerical analysis for the proposed (Al/ZnO/SnO2/CH3NH3SnI3/Ni) device structure. …”
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Spinach ameliorates dietary oxidized tallow-induced NAFLD by regulating inflammatory cytokines, peroxisome proliferator-activated receptors, and antioxidant systems by Neelab, Alam Zeb, Muhammad Jamil

“…Purpose: This study aimed to evaluate the ability of Spinacia oleracea dried powder in protecting rabbits from the toxicity caused by oxidized-tallow. Methods: Oxidized tallow and spinach powder were administered to the rabbits. …”
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Rapid Multi-Well Evaluation of Assorted Materials for Hydrogel-Assisted Giant Unilamellar Vesicle Production: Empowering Bottom-Up Synthetic Biology by Cherng-Wen Darren Tan, Magdalena Schöller, Eva-Kathrin Ehmoser

“…Some leach and contaminate the GUVs, while others require handling toxic material or specialised chemistry, thus limiting their use by novices. …”
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Arsenic Induces Continuous Inflammation and Regulates Th1/Th2/Th17/Treg Balance in Liver and Kidney In Vivo by Xiaoxu Duan, Guowei Xu, Jinlong Li, Nan Yan, Xin Li, Xuping Liu, Bing Li

“…Numerous studies on arsenic-induced hepatonephric toxicity including cancer have been reported. Given that chronic inflammatory response and immune imbalance are associated with oncogenesis, we investigated whether arsenic could influence the hepatic and nephritic expression of inflammatory factors and the differentiation of T cells. …”
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RNA-seq and In Vitro Experiments Reveal the Protective Effect of Curcumin against 5-Fluorouracil-Induced Intestinal Mucositis via IL-6/STAT3 Signaling Pathway by Xuan-ying Wang, Bo Zhang, Yi Lu, Lu Xu, Yi-jie Wang, Bi-yu Cai, Qing-hua Yao

“…Although first-line chemotherapy drugs, including 5-fluorouracil (5-FU), remain one of the major choice for cancer treatment, the clinical use is also accompanied with dose-depending toxicities, such as intestinal mucositis (IM), in cancer patients undergoing treatment. …”
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Satellite microglia: marker of traumatic brain injury and regulator of neuronal excitability by Alicia B. Feichtenbiner, Karinn Sytsma, Ryan P. O’Boyle, Rhonda Mittenzwei, Heather Maioli, Kathryn P. Scherpelz, Daniel D. Child, Ning Li, Jeanelle Ariza Torres, Lisa Keene, Amanda Kirkland, Kimberly Howard, Caitlin Latimer, C. Dirk Keene, Christopher Ransom, Amber L. Nolan

“…Given the proposed mechanisms of toxic protein production and neuroinflammation as possible initiators or contributors to progressive pathology, we examined phosphorylated tau accumulation, microgliosis and astrogliosis using immunostaining in the orbitofrontal cortex, a region often vulnerable across traumatic brain injury exposures, in an age and sex-matched cohort of community traumatic brain injury including both mild and severe cases in midlife. …”
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Impact of leachate from boiled-water-treated plastic products on male reproductive health: Insights from transcriptomic and metabolomic profiling by Xinghua Yu, Rui Yao, Ge Meng, Lingan Zeng, Leyi Zhou, Yingkang Shen, Amali Upekshika Wijayaraja, Reshmi Hareendra Kariyapperuma, Wentao Xu, Yuxiang Mei, Xinyan Gu, Wen-Long Lei, Pengfei Zhang, Fei Sun

“…Histological analysis of the testes and epididymis was conducted, revealing vacuolization and absence of sperms in the seminiferous tubules of mice treated with PP, HDPE, LDPE, and PS, while PET exhibited lower reproductive toxicity. Furthermore, transcriptomic and metabolomic profiling were employed to identify key genes and metabolites related to plastic exposure. …”
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Investigating the Capability of Dandelion Greens to Remediate Soils Contaminated with Cadmium by Zokirov Kurbonalijon Gaybullo Ugli, Annigere S Prakash, Sarah Salah Jalal, Dahlia N. Al-Saidi, Zahraa F. Hassan

“…This study aimed to explore the possibility of removing cadmium, a toxic heavy metal, from soil using Dandelion greens. …”
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Mineral Composition of Four Edible Mushrooms by S. E. Mallikarjuna, A. Ranjini, Devendra J. Haware, M. R. Vijayalakshmi, M. N. Shashirekha, S. Rajarathnam

“…The mushrooms were safe for consumption, in accordance with the permissible tolerance limits of the estimated toxic metals. Implications of the mineral contents on mushroom nutritional value are highlighted.…”
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Performance Study of the Direct-Coupled Photovoltaic Water Pumping System for the Rural-Isolated Agricultural Region in Iraq by Mahmood hussein salman, Adel A. Obed, Ahmed J. Abid

“…However, due to a rise in the oil's price on the international market, toxic pollution from burning oil, high maintenance costs, and short lifespans have been challenged to create more viable alternatives. …”
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Antimalarial Efficacy and Antioxidant Activity of Lophira lanceolata Stem Bark Ethanol Extract Using Plasmodium berghei Induced-Malaria in Swiss Albino’s Mice by Mounvera Abdel Azizi, Noumedem Anangmo Christelle Nadia, Yamssi Cedric, Ngouyamsa Nsapkain Aboubakar Sidiki, Gamago Nkadeu Guy-Armand, Djeussi Doriane Esther, Tientcheu Noutong Jemimah Sandra, Tako Djimefo Alex Kevin, Vincent Khan Payne

“…However, further in vivo toxicity tests are required to guarantee their safety.…”
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Dioxin Control in the Co-processing of Waste Printed Circuit Board and Copper Concentrate with an Ausmelt Furnace by Wei Li, Jia Sun, Deng-Feng Ma, Xian-Long Liu, Sheng Li, Jian-Ye Bei, Ming-Xiu Zhan, Xiao-Qing Lin, Tong Chen

“…Compared with the disposal of WPCB alone, the total concentration and toxic equivalent quantity (TEQ) of dioxins decreased by 14.7–26.8% and 34.7–46.5%, respectively, with the change in the proportion used during co-processing. …”
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EDTA and citric acid on the growth of sunflower (Helianthus annuus L.) under chromium stress: a meta-analysis by Wenjun Wang, Xutang Huang, Fei Zhou, Jun Ma, Jing Wang, Zhenhua Guo

“…This study recommends the addition of any chelating agent or activator, but the content of toxic metals in the soil must first be measured carefully. …”
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Factors related to the development of pneumonia associated with ischemic stroke by Alexis Suárez Quesada, Alexis Álvarez Aliaga, Andrés Quesada Vázquez, Julia Matilde Pupo Jiménez

“…The association of the variables Sociodemographic, personal pathological history, toxic habits, stroke conditions, dysphagia, biochemical and immunonutritional markers with the development of pneumonia associated with ischemic stroke were determined using binary logistic regression.…”
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Nursing of a case of drug-induced hypersensitivity syndrome complicated with multiple organ failure undergoing continuous renal replacement therapy (1例药物超敏反应综合征合并多脏器衰竭行连续性肾脏替代治疗的护理... by SONG Xiaoxiu (宋晓秀), XIAO Li (肖莉)

“…This article summarized clinical data and nursing management of a patient with drug-induced hypersensitivity syndrome characterized by toxic epidermal necrolysis and dermatitis combined with multiple organ failure treated with continuous renal replacement therapy (CRRT). …”
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Preliminary Results of Hyperthermic Intraperitoneal Intraoperative Chemotherapy as an Adjuvant in Resectable Pancreatic Cancer by Antonios-Apostolos K. Tentes, Dimitrios Kyziridis, Stylianos Kakolyris, Nicolaos Pallas, Georgios Zorbas, Odysseas Korakianitis, Christos Mavroudis, Nicolaos Courcoutsakis, Panos Prasopoulos

“…No patient was recorded with gemcitabine-induced toxicity. Conclusions. This clinical study of 21 patients is the first to combine an R0 pancreas cancer resection with HIPEC. …”
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