DISTRIBUTION AND POTENTIAL OF CAMELLIA SPP. IN THE CENTRAL HIGHLANDS, VIETNAM, FOR DEVELOPING HIGH-VALUE PRODUCTS IN THE FOOD INDUSTRY by Thi Thang Long Nguyen, Vu Mai Quynh Luong

“…Camellia extract does not cause acute toxicity and has a blood sugar-lowering effect. Vietnam has much experience growing green tea; the total green tea growing area is 131,200 hectares. …”
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Natural compounds in the management of polycystic ovary syndrome: a comprehensive review of hormonal regulation and therapeutic potential by Jingyi Yuan, Zhenmin Li, Yongjiang Yu, Xiuge Wang, Yunyun Zhao

“…Recently, natural compounds have garnered considerable attention due to their efficacy in hormone modulation and minimal toxicity. Substances such as myo-inositol, resveratrol, berberine, and quercetin have shown promise in mitigating PCOS symptoms. …”
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Evolution of drug therapy in patients with resectable gastric and esophageal‑gastric junction cancer by M. V. Sedova, M. A. Batov, V. S. Tretyak, A. A. Kolomeytseva, V. M. Khomyakov, N. N. Volchenko, A. A. Fedenko, A. D. Kaprin

“…However, according to statistics, less than half of patients complete all adjuvant courses of FLOT chemotherapy due to the high toxicity of the regimen and a decrease in the functional status of patients in the postoperative period. …”
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Essential oil and furanosesquiterpenes from myrrh oleo-gum resin: a breakthrough in mosquito vector management by Eleonora Spinozzi, Marta Ferrati, Cecilia Baldassarri, Paolo Rossi, Guido Favia, Giorgio Cameli, Giovanni Benelli, Angelo Canale, Livia De Fazi, Roman Pavela, Luana Quassinti, Cristiano Giordani, Fabrizio Araniti, Loredana Cappellacci, Riccardo Petrelli, Filippo Maggi

“…A GC–MS-driven untargeted metabolomic analysis revealed 32 affected metabolic pathways in treated larvae. The EO non-target toxicity on Daphnia magna Straus (LC50 = 4.51 μL/L) and its cytotoxicity on a human kidney cell line (HEK293) (IC50 of 14.38 μg/mL) were also assessed. …”
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Safety Profile and Effects of Pulsed Methylprednisolone on Vital Signs in Thyroid Eye Disease by Kai-Ling Yong, Chiaw Ling Chng, Hla Myint Htoon, Lee Hooi Lim, Lay Leng Seah

“…No significant cardiovascular or hepatic toxicity was found. Conclusion. IVMP is relatively safe and efficacious. …”
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Functionalization of collagen fiber with nano-islands of silver via atomic layer deposition to promote bone healing by Sarah Hashemi Astaneh, Leonardo P. Faverani, Harshdeep Bhatia, Eduardo Dallazen, Monique Gonçalves Costa, Edilson Ervolino, Valentim A.R. Barão, Cortino Sukotjo, Christos G. Takoudis

“…Comparison of gingival cells cultured on pristine collagen, and silver-coated collagen, demonstrated that the attained silver nanoparticle size and concentration are below the toxicity level of silver. In vivo assessment in rat model showed the biocompatibility of the Ag/Collagen, and greater new bone formation compared to control. …”
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Impact of Sars-CoV-2 prophylaxis with tixagevimab-cilgavimab in high-risk patients with B-cell malignancies: a single-center retrospective study. by Giovanni Manfredi Assanto , Matteo Totaro, Poggiali Rebecca, Delli Paoli Adele, Annechini Giorgia, D’Elia Gianna Maria, Aji Francesco, Petrucci Luigi, Fazio Francesca, Del Giudice Ilaria, Martelli Maurizio, Micozzi Alessandra, Giuseppe Gentile

“…In particular, patients affected by lymphoproliferative diseases, given the impaired cell-mediated and antibody-mediated immunity and treatment toxicity, develop more often a symptomatic and a more serious disease of Covid-19. …”
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Enhanced electrochemical performance of activated carbon derived from Acacia catechu bark by KOH activation for supercapacitor application by Mishra Pawan Kumar, Aryal Sabin, Bhakta Oli Hari, Shrestha Timila, Sapkota Thakur, Shrestha Ram Lal Swagat, Prasad Bhattarai Deval

“…Conversely, activated carbon sourced from biomass has emerged as a promising substitute due to its abundant presence in nature, high carbon content, and ease of processing with minimal toxicity. This study outlines the production of activated carbon from the matured bark of Acacia catechu through a sequence of processes, including pre-carbonization, carbonization, and activation at varying temperatures utilizing potassium hydroxide (KOH) as an activating agent. …”
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Biogenic Synthesis of Copper and Silver Nanoparticles Using Green Alga Botryococcus braunii and Its Antimicrobial Activity by Anju Arya, Khushbu Gupta, Tejpal Singh Chundawat, Dipti Vaya

“…Furthermore, these biosynthesized nanoparticles were found to be highly toxic against two Gram-negative bacterial strains Pseudomonas aeruginosa (MTCC 441) and Escherichia coli (MTCC 442), two Gram-positive bacterial strains Klebsiella pneumoniae (MTCC 109) and Staphylococcus aureus (MTCC 96), and a fungal strain Fusarium oxysporum (MTCC 2087). …”
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Liver Injury Secondary to Anti-TNF-Alpha Therapy in Inflammatory Bowel Disease: A Case Series and Review of the Literature by Ravish Parekh, Nirmal Kaur

“…All TNF-α inhibitors have been associated with liver toxicity, but many of these cases have been reported in patients receiving therapy for rheumatologic disease. …”
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Defense responses of the green microalgae Chlorella vulgaris to the vanadium pentoxide nanoparticles by Kalehjahi Hanifeh Akbarian, Kosari-Nasab Morteza, Amini Mojtaba, Movafeghi Ali

“…The gained NPs were characterized using XRD, FT-IR, EDS, DLS, SEM and TEM techniques. Subsequently, the toxic effects of V2O5 NPs on the model green microalgae Chlorella vulgaris were evaluated. …”
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PNPO‐Mediated Oxidation of DVL3 Promotes Multiple Myeloma Malignancy and Osteoclastogenesis by Activating the Wnt/β‐Catenin Pathway by Zhendong Deng, Shanliang Sun, Nian Zhou, Yumeng Peng, Long Cheng, Xichao Yu, Yuxia Yuan, Mengjie Guo, Min Xu, Yuexin Cheng, Fan Zhou, Nianguang Li, Ye Yang, Chunyan Gu

“…This study aimed to identify specific targets of celastrol and develop more effective and less toxic treatment options for MM. Celastrol is used as a probe to determine its specific target, pyridoxine‐5′‐phosphate oxidase (PNPO). …”
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Inflammatory disease progression shapes nanoparticle biomolecular corona-mediated immune activation profiles by Jacob R. Shaw, Nicholas Caprio, Nhu Truong, Mehari Weldemariam, Anh Tran, Nageswara Pilli, Swarnima Pandey, Jace W. Jones, Maureen A. Kane, Ryan M. Pearson

“…Our findings illuminate the personalized nature of corona formation under a dynamic inflammatory condition and its impact on NP-mediated immune activation profiles and inflammation, suggesting that disease progression-related alterations in plasma composition can manifest in the corona to cause unintended toxicity and altered therapeutic efficacy.…”
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Comprehensive analysis of naturally occurring radionuclides in well water: Isotopic ratios, mitigation, and dose assessment by Francisco Piñero-García, Rimon Thomas, Eva Forssell-Aronsson, Mats Isaksson

“…In areas with moderate or high abundance of naturally occurring radionuclides in the bedrock, the groundwater could be enhanced with radio and chemically toxic elements such as uranium, radium, lead and polonium. …”
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Alpha synuclein and inflammaging by Geneviève L. Putnam, Robert W. Maitta

“…This is defined as chronic inflammation that accompanies aging observed in many neurodegenerative pathologies, that include α-syn's ability to form oligomers and toxic fibrils seen in PD. This oligomeric α-syn stimulates pro-inflammatory signals, which may worsen PD symptoms and propagate chronic inflammation. …”
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Removal of microplastics by algal biomass from aqueous solutions: performance, optimization, and modeling by Fatemeh Lotfigolsefidi, Mojtaba Davoudi, Maryam Sarkhosh, Ziaeddin Bonyadi

“…Abstract Microplastics (MPs) are emerging pollutants that pose significant risks to ecosystems due to their inherent toxicity, capacity to accumulate various pollutants, and potential for synergistic impacts. …”
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A subcellular sampling instrument allows spatial resolution of amyloid deposit-derived organelle-specific effects in microglia by Robert Subirana Slotos, Tinh Thi Nguyen, Ledjona Fiska, Kristina Friedland, Kristina Endres

“…Moreover, a distance-related gene expression pattern occurs, demonstrating the local initiation of mitochondrial changes of microglia when approaching toxic peptide deposits.…”
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Injecting hope: the potential of intratumoral immunotherapy for locally advanced and metastatic cancer by Marketa Skalickova, Marketa Skalickova, Katerina Hadrava Vanova, Ondrej Uher, Jindriska Leischner Fialova, Jindriska Leischner Fialova, Jindriska Leischner Fialova, Katerina Petrlakova, Michal Masarik, Michal Masarik, Michal Masarik, Michal Masarik, Zdeněk Kejík, Zdeněk Kejík, Pavel Martasek, Karel Pacak, Milan Jakubek, Milan Jakubek

“…New therapeutic approaches like intratumoral immunotherapy, characterized by reduced side effects, cost, and systemic toxicity, offer promising prospects for future applications in clinical oncology. …”
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Inhibition of transcriptional regulation of detoxification genes contributes to insecticide resistance management in Spodoptera exigua by Bo Hu, Yuping Deng, Tao Lu, Miaomiao Ren, Kuitun Liu, Cong Rao, Hailiang Guo, Jianya Su

“…Bioassay results showed that sofalcone significantly enhanced the toxicity (more than 3-fold) of chlorpyrifos and lambda-cyhalothrin against S. exigua larvae. …”
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Comparison of clinico-pathological characteristics and survival of recurrent ovarian cancer patients on seven different chemo-protocols by Sattar Saima, Ahmad Mobasher, Saeed Hamid, Saleem Zikria, Danish Zeeshan, Akhlaq Muhammad

“…These data suggest that CP regimen exhibited improved clinical efficacy and decreased toxicity related non-compliance in recurrent ovarian cancer patients of Lahore.…”
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