Nicotine Impairs the Response of Lung Epithelial Cells to IL-22 by Hannah My-Hanh Nguyen, Jaclene Amber Torres, Sudhanshu Agrawal, Anshu Agrawal

“…Smoking is a major risk factor for pulmonary diseases that include chronic obstructive pulmonary diseases (COPD) and cancer. Nicotine is the toxic and addictive component of tobacco products, like cigarettes, that negatively affects the immune system. …”
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Yinzhihuang injection induces apoptosis and suppresses tumor growth in acute myeloid leukemia cells. by Zhe Huang, Yunfu Shen, Xianming Fan, Qulian Guo, Wenzhe Ma

“…<h4>Background</h4>The unmet needs in treating acute myeloid leukemia(AML) promote us to look for more effective and less toxic therapies. In this study, we discovered that Yinzhihuang injection(YZHI), a traditional Chinese patent medicine for hepatitis treatment, suppressed the growth of AML cells.…”
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Biomass-Derived Adsorbents for Dye and Heavy Metal Removal from Wastewater by Kashir Ali, Muhammad Ussama Javaid, Zaman Ali, Muhammad Junaid Zaghum

“…Wastewater has a high concentration of dyes and heavy metals, which are the two most significant contaminants. Due to their high toxicity and vulnerability, they possess a potential threat to human health as well as the ecosystem. …”
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Acute cerebral edema: a lethal neurological complication in a patient with COVID-19 infection. Case report and literature review by M. Puodžiūnaitė, R. Sadeckaitė, A. Čikotienė

“…More serious medical conditions such as cerebral edema, neuronal degeneration, encephalitis, acute disseminated encephalomyelitis, Guillain-Barre syndrome, Bickerstaff’s brainstem encephalitis, Miller-Fisher syndrome, polyneuritis, toxic encephalopathy, and stroke can occur. Case report. …”
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Nutrient Management for Soybean Crops by Suman Bagale

“…Nutrient requirements for soybean crops vary in concentration, and deviations can cause nutrient deficiency or toxicity in soybean crops. Nutrient availability to soybean crops depends on the available nutrients in the soil solution, the form of available soil nutrients, mode of uptake of nutrients, its interaction with other soil nutrients, soil chemistry, and method of fertilizer application. …”
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Improving paraffin precipitate inhibition using glycine and Palm-based Methyl Ester Sulfonate (MES) eco-friendly inhibitors. by Nazliah Binti Surpina, Mysara Eissa Mohyaldinn, Abdullah Abduljabbar, Mohammed Abdalla Ayoub

“…However, traditional chemical inhibitors present problems due to their high toxicity and low biodegradability, leading to increased operational costs and environmental concerns. …”
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Study on the Properties of Polyurethane–Urea Elastomers Prepared by TDI/MDI Mixture by Xiangcheng Bian, Jiaguo He, Maoyong He, Bingxiao Liu, Yinzhu Zhang

“…Hence, 4,4′-diphenylmethane diisocyanate (MDI), an isocyanate with significantly lower toxicity compared to TDI, was used as a partial substitute for TDI to prepare PUU through the prepolymerization method with other raw materials including polytetramethylene glycol (PTMG) and 4,4′-methylene-bis(2-chloroaniline) (MOCA) in this paper. …”
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Characterization of heavy metal contamination in groundwater of typical mining area in Hunan Province by Wenjie Hao, Huan Liu, Shuli Hao, Kuanzhen Mao

“…Abstract Heavy metal pollution in mining areas is a major cause of groundwater contamination, characterized by high toxicity, difficult degradability, and easy accumulation, and the source of pollution is not easily identified. …”
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Pilot Study of Trace Elements in the Infusion of Medicinal Plants Used for Diabetes Treatment by Eid I. Brima, Saifeldin M. Siddeeg

“…Momordica charantia exhibited high levels of essential (Mn (251.4), Co (1.18), Cu (54.64), and Se (2.18)) and toxic elements (Al (39.20), As (0.57), Cd (0.33), and Pb (4.48)), followed by Syzygium aromaticum (Mn (736.36)) and Boswellia carterii (Pb (0.93)), which exceeded the PMTDI in traditional doses used for diabetes treatments. …”
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Comparative Evaluation of the Antidiabetic Effects of Different Parts of Cassia fistula Linn, a Southeast Asian Plant by John Wilking Einstein, Mustafa Mohd Rais, Mustafa Ali Mohd

“…The hypoglycemic effect of the methanolic and aqueous extracts of whole parts of Cassia fistula in both normoglycemic and streptozotocin-nictotinamide induced Type 2 diabetic rats were investigated. Acute toxicity, oral glucose tolerance test and glucose uptake in isolated rat hemidiaphragm were performed in normal rats. …”
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Growth, Water Relations, and Photosynthetic Activity Are Associated with Evaluating Salinity Stress Tolerance of Wheat Cultivars by Abeer Hamdy Elhakem

“…The wheat cultivars were otherwise exposed to anatomical characteristics and photosynthetic gas exchange investigations. NaCl toxicity induced a noticeable reduction in stomatal aperture area (SAA), stomatal conductance (Gs), transpiration rate (Tr), and leaf net photosynthetic rate (Pn). …”
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Recent advances in small molecule LpxC inhibitors against gram-negative bacteria (2014–2024) by Pengpeng Ji, Meng Ma, Xiaoyue Geng, Jian Zhang

“…This paper mainly focuses on the structure optimization, conformational relationship and animal toxicity of small molecule LpxC inhibitors over the past 10 years, especially in the last 5 years, in order to provide ideas for the development and clinical research of LpxC inhibitors.…”
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International Normalized Ratio (INR) Increases amongst Two Patients Living with HIV on Warfarin after Being Switched from a Nevirapine to a Dolutegravir-Based Antiretroviral Regime... by Natalie Sang, Sonak Pastakia, Samuel Nyanje

“…Upon discontinuing nevirapine, close monitoring of drugs with narrow therapeutic indices is paramount since dosing requirements may significantly reduce, increasing the probability of toxicity development. We present two cases describing interactions experienced by patients living with HIV, while transitioning from nevirapine to dolutegravir-based HIV regimens. …”
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The Role of Insulin, Insulin Growth Factor, and Insulin-Degrading Enzyme in Brain Aging and Alzheimer's Disease by Claude Messier, Kevin Teutenberg

“…Such a decrease involves the insulin receptor cascade and can also increase amyloid toxicity. Insulin and IGF-I may modulate brain levels of insulin degrading enzyme, which would also lead to an accumulation of Aβ amyloid.…”
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The Aging GABAergic System and Its Nutritional Support by Demetra J. Mills

“…In addition, declines in GABAergic function can also be tied to vitamin status and to toxic chemicals in the food supply. The decline in GABAergic function associated with aging has an effect on just about every body organ system. …”
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Evaluating Traditional Chinese Medicine and Herbal Products for the Treatment of Gestational Diabetes Mellitus by Yang Xin Zi Xu, Shengyan Xi, Xiaoyan Qian

“…None of the herbal medicine and products examined reported toxicity in the experimental models. Overall, treatments of gestational diabetes by western or alternative interventions are grossly understudied. …”
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Systematic Review into Diagnostics for Post-Kala-Azar Dermal Leishmaniasis (PKDL) by Emily R. Adams, Inge Versteeg, Mariska M. G. Leeflang

“…Identification of post-kala-azar dermal leishmaniasis (PKDL) is important due to the long and toxic treatment and the fact that PKDL patients may serve as a reservoir for visceral leishmaniasis (VL). …”
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PK/PD-Guided Strategies for Appropriate Antibiotic Use in the Era of Antimicrobial Resistance by Tetsushu Onita, Noriyuki Ishihara, Takahisa Yano

“…First, we discuss the importance of drug concentration management for enhancing efficacy while preventing toxicity, considering various patient populations, including pediatric and elderly patients with their unique physiological characteristics. …”
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Comparison of rituximab vs. cyclophosphamide in rheumatoid arthritis-associated interstitial lung disease and its correlation with spirometry by Mohammed Abdullah Saleem, Atiya Parveen, Fazeel Zubair Ahmed

“…This study outlines the limitations of current treatment options. Specifically, the toxicity of cyclophosphamide sets the stage for investigating the comparative effectiveness of rituximab in the context of RA-ILD. …”
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The Evaluation of Impact of Cable Power Lines on the Environment by M. A. Korotkevich, S. N. Azarov

“…To evaluate the environmental impact of electrical cable materials, an approach has been developed that takes into account not only the toxicity of the materials but also their volumetric content in the cable. …”
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