Aflatoxin B1 impairs the growth and development of chicken PGCs through oxidative stress and mitochondrial dysfunction by Ying-Jie Niu, Jun Wu, Wenjie Ren, Guangzheng Liu, Gaoyuan Wu, Yixiu Peng, Dan Zheng, Kai Jin, Qisheng Zuo, Guohui Li, Wei Han, Xiang-Shun Cui, Guohong Chen, Bichun Li

“…This study illuminates AFB1's toxic effects on chicken PGCs and provides insights into potential mechanisms, establishing a basis for strategies to prevent and treat AFB1's adverse effects on poultry genetic transmission.…”
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A review of Psoralea corylifolia L.: a valuable plant with profound biological significance by Anni Yang, Lingping Kong, Zhibo You, Xinyu Li, Jian Guan, Fengjin Li, Lingyun Zhong, Hai Jiang

“…In the future, it will be necessary to focus on the active metabolites of PCL, analyze its targets and signaling pathway network to address potential toxicity and side effects in clinical applications, and further expand the potential application of PCL in medicine.…”
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Atmospheric pressure plasma synthesis of adaptable coatings based on castor oil urethane dimethacrylate and their properties by Eusebiu-Rosini Ionita, Maria-Daniela Ionita, Antoniu Moldovan, Cristina Surdu-Bob, Violeta Melinte, Andreea L. Chibac-Scutaru, Andrada Lazea-Stoyanova

“…In short, our plasma-based method for generation of CO-PMA layers, in dynamic mode, does not require toxic photoinitiators, is simple, can be applied to temperature-sensitive materials and is scalable to large areas.…”
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Nanoparticles in Hormonal Regulation of the Female Reproductive System by Vandhana Vijayakumar, Thirumalaikumaran Rathinam, Sakthi Sanjana Deenadhayalan, Elizabeth Rani Edwin, Preethi Harikrishnan, Prathiba Balaji

“…However, the accumulation of NPs in reproductive organs raises concerns about their potential toxicity, particularly in terms of oxidative stress, inflammation, and DNA damage. …”
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Pesticides in Honeybee Products—Determination of Pesticides in Bee Pollen, Propolis, and Royal Jelly from Polish Apiary by Agata Swiatly-Blaszkiewicz, Agnieszka Klupczynska-Gabryszak, Eliza Matuszewska-Mach, Joanna Matysiak, Everaldo Attard, Dariusz Kowalczyk, Aleksandra Adamkiewicz, Bogumiła Kupcewicz, Jan Matysiak

“…It should be noted that any dose of pesticides can cause a health hazard due to toxicity, since these substances may act synergistically. …”
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Ciprofloxacin and Clozapine: A Potentially Fatal but Underappreciated Interaction by Jonathan M. Meyer, George Proctor, Michael A. Cummings, Laura J. Dardashti, Stephen M. Stahl

“…The postmortem femoral clozapine plasma level was dramatically elevated at 2900 ng/mL, and the cause of death was listed as acute clozapine toxicity. Conclusion. Given the potentially fatal pharmacokinetic interaction between clozapine and ciprofloxacin, clinicians are advised to monitor baseline clozapine levels prior to adding strong CYP450 1A2 inhibitors, reduce the clozapine dose by at least two-thirds if adding a 1A2 inhibitor such as ciprofloxacin, check subsequent steady state clozapine levels, and adjust the clozapine dose to maintain levels close to those obtained at baseline.…”
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Treatment of LF slag to prevent powdering during cooling by Ghorai S., Mandal G.K., Roy S., Minj R.K., Agarwal A., Singh D.P., Kumar A., Ramna R.B.V.

“…Dust formation can also be prevented by decreasing the ladle furnace slag basicity to about 1.7. Toxicity Characteristic Leaching Procedure test, of the borax and barium carbonate treated slag samples, indicates that barium carbonate treated slag cannot be used for the dusting prevention as it contains high level of barium.…”
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Insulin Facilitates the Recovery of Myocardial Contractility and Conduction during Cardiac Compression in Rabbits with Bupivacaine-Induced Cardiovascular Collapse by Solmon Yang, Tserendorj Uugangerel, In-ki Jang, Hyung-chul Lee, Jong Min Kim, Byeong-Cheol Kang, Chong Soo Kim, Kook-Hyun Lee

“…We hypothesizes that insulin therapy would be effective in resuscitating bupivacaine-induced cardiac toxicity in rabbits. Twelve rabbits were tracheally intubated and midline sternotomy was performed under general anesthesia. …”
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Current Status of Human Adipose–Derived Stem Cells: Differentiation into Hepatocyte-Like Cells by Feras Al Battah, Joery De Kock, Tamara Vanhaecke, Vera Rogiers

“…In this review, we will not only present recent data regarding hASC biology, their isolation, and differentiation capability towards hepatocytes, but also the potential application of hASC-derived hepatocytes to study drug toxicity. Additionally, this review will discuss the therapeutic potential of hASCs as undifferentiated cells in liver regeneration.…”
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Selecting first-line immunotherapy in advanced melanoma: Current evidence on efficacy across diverse patient populations by Sophia Kreft, Tommaso Bosetti, Rebecca Lee, Paul Lorigan

“…Since most patients who respond to combination ipilimumab-nivolumab also respond to nivolumab-relatlimab, and many to single-agent anti-programmed death-1 (PD-1) monotherapy, the challenge is to identify the subgroup of patients who need ipilimumab-nivolumab and would not achieve similar benefits from less toxic alternatives. This review discusses the available data on efficacy of the three approved first-line immunotherapies (single-agent anti-PD-1, nivolumab-relatlimab or ipilimumab-nivolumab) and their value in distinct population groups to help guide clinical decisions.…”
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Ornamental Exterior versus Therapeutic Interior of Madagascar Periwinkle (Catharanthus roseus): The Two Faces of a Versatile Herb by Naghmeh Nejat, Alireza Valdiani, David Cahill, Yee-How Tan, Mahmood Maziah, Rambod Abiri

“…TIAs are present only in micro quantities in the plant and are highly poisonous per se rendering a challenge for researchers to increase yield and reduce toxicity.…”
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Genomic signatures of adaptation in native lizards exposed to human-introduced fire ants by Braulio A. Assis, Alexis P. Sullivan, Stephanie Marciniak, Christina M. Bergey, Vanessa Garcia, Zachary A. Szpiech, Tracy Langkilde, George H. Perry

“…In the 1930s red imported fire ants (Solenopsis invicta) were accidently introduced to the Southeastern USA, where today they are both venomous predators and toxic prey to native eastern fence lizards (Sceloporus undulatus). …”
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The Exploitation of Nanotechnology in Herbicides and Bioherbicides: A Novel Approach for Sustainable Weed Management by Mirko La Iacona, Aurelio Scavo, Sara Lombardo, Giovanni Mauromicale

“…However, further research is still required to assess their effectiveness under natural conditions, improve their stability over time and study their bioaccumulation and toxicity toward non-target organisms.…”
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Advances in electrochemical sensors for naproxen detection: Mechanisms, performance factors, and emerging challenges by Seyed Saman Nemati, Gholamreza Dehghan, Jafar Soleymani, Abolghasem Jouyban

“…However, its use has complications such as changes in kidney function, severe gastrointestinal lesions, and increased bleeding after surgery. In addition, the toxicity of NAP or its metabolites affects the organisms in the ecosystem. …”
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Micromorphological and Chemical Approaches to Understand Changes in Ecological Functions of Metal-Impacted Soils under Various Land Uses by J. A. Acosta, S. Martinez-Martinez, A. Faz, J. M. Van Mourik, J. M. Arocena

“…We investigated the changes in faunal activities as measures of the ecological functions of soils impacted by potentially toxic metals (PTMs) under urban, industrial, agricultural, and natural uses. …”
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Present Status of Ganges River Dolphins Platanista gangetica gangetica (Roxburgh, 1801) in the Turag River, Dhaka, Bangladesh by Mohammad Abdul Baki, Naser Ahmed Bhouiyan, Md. Saiful Islam, Shayer Mahmood Ibney Alam, Shibananda Shil, Md. Muzammel Hossain

“…Freshwater ecosystem degradation in the Turag River basin is increasing due to rising human settlement, reduced water flow during the dry season, new large land development projects, and toxic emissions caused by brick kilns. The population of river dolphins was estimated through surveys carried out from December 2012 to November 2013. …”
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Precise HER2 Protein Degradation via Peptide‐Conjugated Photodynamic Therapy for Enhanced Breast Cancer Immunotherapy by Changyong Guo, Fei Gao, Guoyuan Wu, Jinqiu Li, Chunquan Sheng, Shipeng He, Honggang Hu

“…Traditional treatments combining the anti‐HER2 antibody trastuzumab with immunotherapy face limitations due to toxicity and tumor microenvironment immunosuppression. …”
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Utilization Patterns and Projected Demand of Antiretroviral Drugs in Low- and Middle-Income Countries by Françoise Renaud-Théry, Carlos Avila-Figueroa, John Stover, Sigrid Thierry, Marco Vitoria, Vincent Habiyambere, Yves Souteyrand

“…Despite the global economic crisis and in response to the revised treatment guidelines, our model forecasts an increasing and shifting demand for antiretrovirals in resource-limited settings not only to provide treatment to new patients, but also to those switching to less toxic regimens.…”
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Management of Maillard reaction-derived reactive carbonyl species and advanced glycation end products by tea and tea polyphenols by Yue Luo, Jianan Zhang, Chi-Tang Ho, Shiming Li

“…Further studies need to address on aspects like exact mechanisms, solution of detection obstacles, balance of practical usage and harmful effects such as potential flavor damage and toxicity in food, to gain a comprehensive understanding of antiglycation activities of tea polyphenols and its actual application.…”
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Technical explorations for manufacturing of NiTi unibody vascular stents through metal injection molding: Materials performance, fatigue properties and biocompatibility by Dongyang Li, Junwei Wang, Changhai Du, Hao He, Zheyu He, Tun Wang, Chang Shu, Yimin Li, Jing Pan

“…The biocompatibility of MIM NiTi was evaluated based on toxicity, migration, and adhesion of the human umbilical vein endothelial cells. …”
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