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2761
Laser-induced degradation of organophosphorus compounds
Published 2002-01-01“…The compounds detected in the irradiated samples suggest that diazinon is converted directly into 2-isopropyl-4-methyl-6-hydroxypyrimidine without the formation of more toxic diazoxon. This transformation involves oxidation of the sulphur atom to the sulphate anion.…”
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2762
Latest Approved Therapies for Metastatic Melanoma: What Comes Next?
Published 2013-01-01“…Improved therapeutic protocols shall overcome therapeutic limitations such as the (i) tolerability and safety (i.e., minimal toxic side-effects); (ii) progression free survival (e.g., reduced relapse disease frequency); (iii) duration response (i.e., decreased drug resistance). …”
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2763
New Applications in Gas Geochemistry
Published 2020-01-01“…Quantitative analysis of methane and CO2 migration is important for climate change studies. Some of them are toxic (H2S, CO2, CO); radon is responsible for the major part of human radiation dose. …”
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2764
Is PPAR𝛾 a Prospective Player in HIV-1-Associated Bone Disease?
Published 2009-01-01“…However, chronic use of ART has been associated with a number of toxicities; including significant reductions in bone mineral density (BMD) and disorders of the fat metabolism. …”
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2765
HIV-Associated Neurotoxicity: The Interplay of Host and Viral Proteins
Published 2021-01-01“…In-depth research in the pathogenesis of HIV has focused on various mechanisms involved in neuronal dysfunction and associated toxicities ultimately showcasing the involvement of various pathways. …”
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2766
Molluscicidal Activity of Some Solanum Species Extracts against the Snail Biomphalaria alexandrina
Published 2009-01-01“…A phytochemical analysis of chloroform: ethanol extract was performed to search for active toxic ingredient. The lethal concentration was determined. …”
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2767
Coverage bias in small molecule machine learning
Published 2025-01-01“…Abstract Small molecule machine learning aims to predict chemical, biochemical, or biological properties from molecular structures, with applications such as toxicity prediction, ligand binding, and pharmacokinetics. …”
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2768
Carbon dioxide utilization: CO2-based polyurethane foam
Published 2025-01-01“…CO2, a promising C1 resource, can be permanently fixed in polymers, making it abundant and non-toxic. The development of CO2-based polymers, such as rubbers and plastics, for mainstream industrial applications, could significantly reduce CO2 concentration in the atmosphere and decrease the reliance on fossil resources. …”
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2769
Applying different techniques for evaluating the resistance to moisture of electrospun PVA nanofibers
Published 2021-08-01“… Poly (Vinyl Alcohol) (PVA) is used to produce nanofibers with electrospinning for several applications related to the non-toxicity of the material, however, the application in air filtration in hindered by the high hydrophilicity of the material, which requires the crosslinking with additives. …”
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2770
Ultrasonography of the Kidneys in Healthy and Diseased Camels (Camelus dromedarius)
Published 2020-01-01“…Congestion, hemorrhage, hydronephrosis, acute glomerulonephritis, subacute glomerulonephritis, chronic glomerulonephritis, diffuse interstitial nephritis, focal interstitial nephritis, renal cyst, hyaline degeneration, renal amyloidosis, tubular nephrosis, pyelonephritis, hemosiderosis, and renal toxicity. When the kidney is examined by ultrasonography, the clinician can get sufficient information about the size, position, and echo patterns of the renal cortex and medulla and renal pelvis and outlines of the renal blood vessels. …”
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2771
MS-1
Published 2016-04-01“…Here, we show that the constitutive expression of the magA gene from Magnetospirillum magnetotacticum is tolerated by human embryonic kidney (HEK) cells but induces a strong toxic effect in murine mesenchymal/stromal cells and kidney-derived stem cells, severely restricting its effective use as a reporter gene for stem cells. …”
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2772
Production of Emulsion Paint Using Locally Available Materials.
Published 2024“…Many toxic chemicals such as titanium dioxide are used in the manufacture of chemical paints. …”
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2773
A modular approach to catalytic stereoselective synthesis of chiral 1,2-diols and 1,3-diols
Published 2025-01-01“…However, their synthesis relies on the use of toxic or expensive metal catalysts or suffer from low regioselectivity. …”
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2774
Advanced surface-enhanced raman scattering nanoprobes for precise detection of Nitroreductase in Hypoxic tumor cells: Improving Cancer diagnosis
Published 2025-02-01“…This novel approach allows for the accurate quantification of NTR, with the sensitivity reaching a detection threshold of less than 0.02 μg/mL. The probe's non-toxic nature and superior biocompatibility facilitate its use for direct SERS investigations in A549 cells under reduced oxygen levels. …”
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2775
Current Status of Gout Arthritis: Current Approaches to Gout Arthritis Treatment: Nanoparticles Delivery Systems Approach
Published 2025-01-01“…Nanoparticle drug delivery enhances biological availability and delivery to targets, which may increase therapeutic efficacy and decrease general toxicity. The preventive approach again cannot be ignored, mainly keeping up certain modifications in diet and weight, along with pharmacological therapies to reduce uric acid (UA) levels and to decrease the frequency of acute attacks. …”
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2776
Comprehensive assessment of water and sediment quality in Lake Nasser, Egypt, using various potential risk indices
Published 2024-04-01“…Ni has the highest EF and I-geo values, while Ni and Cd contributed the most to the ecological risk and toxic risk index. The obtained results revealed that Cd and Ni in the sediments may pose a threat to organisms living in Lake Nasser.…”
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2777
Hyaluronidase-responsive hydrogel loaded with magnetic nanoparticles combined with external magnetic stimulation for spinal cord injury repair
Published 2025-02-01“…The hydrogel was further combined with Neurotrophic growth factor (NGF) and Fe3O4 nanoparticles, exhibiting low toxicity, good mechanical properties, self-healing ability, and sustained drug release. …”
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2778
Gold nanorod-based engineered nanogels for cascade-amplifying photothermo-enzymatic synergistic therapy
Published 2024-12-01“…Among these, cooperative physical and biochemical activation strategies have attracted increasing attention because of their spatiotemporal controllability, low toxicity, and high therapeutic efficacy. Herein, we demonstrate a nanogel complex as a multilevel ROS-producing system by integrating chloroperoxidase (CPO) into gold nanorod (AuNR)-based nanogels (ANGs) for cascade-amplifying photothermal-enzymatic synergistic tumor therapy. …”
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2779
Immunological disturbance effect of exogenous histamine towards key immune cells
Published 2024-07-01“…Histamine in food has attracted widespread attention due to the potential toxicity and associated health risk. However, its influences on immunological components, especially the function of key immune cells, are still poorly known. …”
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2780
Autonomous Defense Based on Biogenic Nanoparticle Formation in Daunomycin-Producing <i>Streptomyces</i>
Published 2025-01-01“…Daunomycin is a chemotherapeutic agent widely used for the treatment of leukemia, but its toxicity toward healthy dividing cells limits its clinical use and its production by fermentation. …”
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