Anti-Müllerian Hormone as a Sensitive Marker of Ovarian Function in Young Cancer Survivors by Maryna Krawczuk-Rybak, Elzbieta Leszczynska, Marta Poznanska, Beata Zelazowska-Rutkowska, Jolanta Wysocka

“…We evaluated ovarian function by measuring the levels of anti-Müllerian hormone (AMH), estradiol, and gonadotropins in 83 young women treated for cancer during childhood and adolescence, and classified according to post-treatment gonadal toxicity versus 38 healthy females. Results. The mean AMH values were lower in the entire cohort independently of the risk group as compared to the control, whereas FSH was elevated only in the high risk group. …”
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The General Principle of the Warburg Effect as a Possible Approach for Cancer Immunotherapy: The Regulatory Effect of Plant Extracts Could Change the Game by Donika Ivanova, Severina Semkova, Boncho Grigorov, Milena Tzanova, Ana Georgieva, Dancho Danchev, Biliana Nikolova, Zvezdelina Yaneva

“…Because of the reported serious adverse effects of using synthetic ligands for PPARs in combination with chemotherapeutics, searches for less toxic and more active PPAR inhibitors, as well as blocking undesirable cellular PPAR-dependent processes, are in progress. …”
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Association between air pollution and osteoporosis: A systematic review by Prabowo Nurhasan Agung, Soetrisno, Nurwati Ida, Ardyanto Tonang Dwi, Poncorini Eti, Nurudhin Arief, Dirgahayu Paramasari

“…These mechanisms include oxidative stress, systemic inflammation, and heavy metal toxicity in women disproportionately, older adults and urban populations. …”
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Rescue RM/CS-AKI by blocking strategy with one-dose anti-myoglobin RabMAb by Xinyue Wang, Ning Li, Lu Han, Ou Qiao, Xin Chen, Pengtao Wang, Lancao Zhang, Yingjie Hou, Fengjiao Bao, Herui Hao, Sania Saeed, Li Zhang, Zizheng Li, Xiaohong Duan, Shuquan Rao, Zichuan Liu, Yanhua Gong

“…The optimal administration strategy, pharmacokinetic analysis, toxicity evaluation for anti-Mb RabMAb, and the distribution of its immune complexes in RM/CS-AKI mice are investigated. …”
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Influence of Alkali Treatment on the Surface Area of Aluminium Dross by N. S. Ahmad Zauzi, M. Z. H. Zakaria, R. Baini, M. R. Rahman, N. Mohamed Sutan, S. Hamdan

“…Aluminium dross is an industrial waste from aluminium refining industry and classified as toxic substances. However, the disposal of dross as a waste is a burden to aluminium manufacturer industries due to its negative effects to the ecosystem, surface, and ground water. …”
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Study of interaction between metal ions and quercetin by Taiane Souza de Castilho, Tatiane Brescovites Matias, Keller Paulo Nicolini, Jaqueline Nicolini

“…This investigation serves as a tool for the development and testing of materials capable of capturing toxic metal ions or favoring the absorption of beneficial ions (in relation to the human metabolism) through the construction of efficient bioorganic systems. …”
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Preparation and Optimization of 10-Hydroxycamptothecin Nanocolloidal Particles Using Antisolvent Method Combined with High Pressure Homogenization by Bolin Lian, Yong Li, Xiuhua Zhao, Yuangang Zu, Ying Wang, Yin Zhang, Yuanyuan Li

“…The aim of this study was to prepare 10-hydroxycamptothecin nanocolloidal particles (HCPTNPs) to increase the solubility of drugs, reduce the toxicity, improve the stability of the drug, and so forth. …”
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Novel cisplatin-magnetoliposome complex shows enhanced antitumor activity via Hyperthermia by M. Carmen Jiménez-López, Ana Carolina Moreno-Maldonado, Natividad Martín-Morales, Francisco O’Valle, M. Ricardo Ibarra, Gerardo F. Goya, Ignacio J. Molina

“…The ML has no significant toxicity both in vitro and in vivo and, most importantly, enhances cell death by apoptosis after magnetic hyperthermia. …”
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Edaphic Diversity, Polychemical Soil Status of the Prinevskaya Lowland and Prospects for Soils Use by Ekaterina Yu. Chebykina, Timur I. Nizamutdinov, Evgeny V. Abakumov, Natalia V. Dinkelaker

“…The most vulnerable land use are forest and agricultural and fallow zones, where active accumulation of priority toxicants of anthropogenic origin can occur. Geochemical peculiarities of studied soils are deficit of Mn, Cu, Mo, and Zn in soil-forming rock materials and accumulation of strontium and lead in arable horizons. …”
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Neuropsychological profiles of patients suffering from hallucinogen persisting perception disorder (HPPD): A comparative analysis with psychedelic-using and non-using controls by Georg Leistenschneider, Tomislav Majić, Simon Reiche, Thomas G. Riemer

“…Abstract Classic psychedelics like LSD and psilocybin are showing promising effects in treating certain psychiatric disorders. Despite their low toxicity and lack of an addictive potential, in some individuals, psychedelics can be associated with persisting psychological harms. …”
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Potential Nephroprotective Effect of Kaempferol: Biosynthesis, Mechanisms of Action, and Clinical Prospects by Maulana Yusuf Alkandahri, Asman Sadino, Barolym Tri Pamungkas, Zulpakor Oktoba, Maya Arfania, Nia Yuniarsih, Eko Sri Wahyuningsih, Yuliani Dewi, Sri Ayu Winarti, Sri Tantia Dinita

“…Kidney is an essential organ that is highly susceptible to cellular injury caused by various toxic substances in the blood. Several studies have shown that untreated injuries to this organ can cause glomerulosclerosis, tubulointerstitial fibrosis, and tubular cell apoptosis, leading to kidney failure. …”
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Promising New Treatments for Psoriasis by Sarah Dubois Declercq, Roxane Pouliot

“…Biological drugs are less toxic to the body and more effective than traditional therapies. …”
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Chemical Profiling Ethyl Acetate Extract of <i>Basilicum polystachyon</i> Leaves and Exploration of Anticancer SIRT1 Inhibitors Using <i>In Silico</i> Approach by Tukiran Tukiran, Muhammad Raihan

“…Natural products are the primary source of medicinal compounds believed to have lower toxicity and side effects than synthetic drugs. This research aimed to reveal the chemical profile of the ethyl acetate extract of Basilicum polystachyon leaves. …”
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Betalains protect various body organs through antioxidant and anti-inflammatory pathways by Nilesh Prakash Nirmal, Seema Medhe, Merina Dahal, Pankaj Koirala, Siriwan Nirmal, Fahad Al-Asmari, Baojun Xu

“…However, these organs can be affected or damaged by various stress factors, toxicants, and harmful substances. Recent studies have claimed that betalains could protect all vital organs of the body through antioxidant and anti-inflammatory mechanisms. …”
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Bioactive extracts from the industrial byproduct of passion fruit promote better glycemic control in an adjuvant treatment with insulin and prevent kidney and heart damage in rats... by Bárbara Cabral, Ony Araújo Galdino, Iago de Souza Gomes, Jovelina Samara Ferreira Alves, José Ivan Marques, Karla Simone Costa de Souza, Rodrigo Moreira da Silva, Bento João Abreu, Norberto Peporine Lopes, Silvana Maria Zucolotto, Adriana Augusto de Rezende

“…Extracts were produced using eco-friendly solvents and evaluated in a T1DM chronic model. Acute toxicity tests showed the extracts (2000 mg/kg, orally) were safe. …”
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Coronary Artery and Peripheral Vascular Disease in a Patient with Poorly Differentiated Thyroid Cancer Treated with the Tyrosine Kinase Inhibitor Lenvatinib by Vineeth Sukrithan, Lisa Kim, Jennifer A. Sipos, Ashima Goyal, Ye Zhou, Daniel Addison, Manisha Shah, Bhavana Konda, Ajay Vallakati

“…However, in the phase III SELECT trial of the drug in thyroid cancer, 5.4% of patients on lenvatinib experienced arterial thromboembolic events, with 2.7% experiencing severe grade ≥3 toxicities associated with arterial vascular events. …”
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Environmental impact assessment of southern tehran wastewater treatment plant using life cycle assessment (LCA) by Zeinab Samsami, Ahmad Jonidi Jafari, Mohammad Delnavaz, Azra Naderi, Reza Barati Rashvanlou, Behnam Movassagh Inchehboroun, Emad Dehghanifard

“…Although the use of treated wastewater and digested sludge for agricultural land may save a significant amount of water, it has significant adverse effects on carcinogenic and noncarcinogenic toxicity in humans due to the presence of heavy metals and has a negative effect on global warming.…”
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Comparative Studies on the pH Dependence of DOW of Microcystin-RR and -LR Using LC-MS by Gaodao Liang, Ping Xie, Jun Chen, Ting Yu

“…The difference of hydrophobicity in acidic condition between MC-RR and -LR is important, not only for the analytical method of both toxins, but perhaps also for understanding the difference of toxicity to animals between the two toxins.…”
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Occurrence of Surface Active Agents in the Environment by Ewa Olkowska, Marek Ruman, Żaneta Polkowska

“…Additionally, SAAs present in the environment can be accumulated in living organisms (bioaccumulation), what can have a negative effect on biotic elements of ecosystems (e.g., toxicity, disturbance of endocrine equilibrium). They also cause increaseing solubility of organic pollutants in aqueous phase, their migration, and accumulation in different environmental compartments. …”
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How Do MRI Findings Influence Rectal Cancer Management? by Ayloor Seshadri Ramakrishnan, Jeyakumar Pradeep

“…Treatment of rectal cancer is currently guided by the need to reduce local recurrence, improve survival, reduce treatment-related toxicity, and improve the patient's quality of life (QoL). …”
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