Leflunomide induced drug reaction with eosinophilia and systemic symptoms: A lesser known entity by Deepak Vashisht, Madhab Durga Tripathy, Sunmeet Sandhu, Rohit Kothari, Surbhi Vashisht, Arun Hegde

“…Features mimicking Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS-TEN), sepsis, Kawasaki disease andhyper-eosinophilic syndrome can cause immense diagnostic dilemma. …”
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Extrapulmonary Tuberculosis Leading to Abdominal Wall Mass in Young Patient by Mohadeseh Karimi, Ali AtashAbParvar

“…The patient was oriented and not ill or toxic in general appearance. Vital signs were within normal ranges. …”
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Interplay of p23 with FKBP51 and their chaperone complex in regulating tau aggregation by Pijush Chakraborty, Markus Zweckstetter

“…We further show that the p23-FKBP51 complex binds tau to form a dynamic p23-FKBP51-tau trimeric complex that delays tau aggregation and thus may counteract Hsp90-FKBP51 mediated toxicity. Taken together, our findings reveal a co-chaperone mediated Hsp90-independent chaperoning of tau protein.…”
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Differential impact from individual versus collective misinformation tagging on the diversity of Twitter (X) information engagement and mobility by Junsol Kim, Zhao Wang, Haohan Shi, Hsin-Keng Ling, James Evans

“…Detailed comparison demonstrated differences in toxicity, sentiment, readability, and delay in individual versus collective misinformation tagging messages. …”
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Evaluating the Smoothness of the Washed Fabric after Laundry with the Washing Machine Based on a New Type-2 Fuzzy Neural Network by Mir Saeid Hesarian, Jafar Tavoosi

“…The washing process was done without any softener as toxic material. For this purpose, experimental and theoretical evaluations were conducted. …”
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A Review on the Antimutagenic and Anticancer Effects of Cysteamine by Chun-Man Lee

“…These methods can be associated with serious adverse events and can be toxic to healthy cells. Despite the new advances in cancer therapies, there is still a continuous need for safe and effective therapeutic agents. …”
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The Efficacy of Chlorantraniliprole as a Seed Treatment for Mythimna separata (Walker) (Lepidoptera: Noctuidae) by Hongbo Li, Changgeng Dai, Yang Hu

“…Similar to results obtained in pots, the residual toxicity of CHL and CHL + CLO to OAW larvae in the field declined with DAE and larval development. …”
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Synthesis and Characterization of a Biodegradable and Robust Film Using Gracilarialichenoides and Sargassumhorneri for Packaging Applications by Wan Young Cha, Chan Byon

“…A hazardous material test was conducted in accordance with IEC62321, and the result indicated that all of the concerned toxic material was estimated to be under the method detection limit (MDL). …”
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Screening of potential GCMS derived antimigraine compound from the leaves of Abrus precatorius Linn to target “calcitonin gene related peptide” receptor using in silico analysis... by Parthasarathy V., Ajay Kumar T.V

“…Many strategies were employed to design antimigraine drug using various CGRP antagonist/ligands but most of them have failed due to their inability to reach the target “CGRP receptor” as they get metabolized before conferring their pharmacological action and exhibit toxic effect to the liver. The present study, evaluated the binding of 13 phyto-chemical compounds of “Abrus precatorius” identified through GCMS analysis against the protein CGRP using “Discovery Studio software”. …”
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Metal Oxide Nanomaterials as Rice Transgenic Carriers by Xiangbo Yang, Xia Bai, Zhenkai Zhang, Xiaoming Yu

“…This sheds light on the toxic effects of metal oxide nanomaterials on rice growth and discusses the factors that affect the phytotoxicity of nanomaterials. …”
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Pain at chronic pancreatitis: origin and treatment options by V. T. Ivashkin, K. V. Ivashkin, A. V. Okhlobystin

“…To present basic mechanisms of pain at pancreatitis and determine main management approaches in pain-predominant cases.Summary. Direct toxic action of damaging factors (first of all — alcohol), pancreatic enzyme deviation phenomenon, parenchymal damage by overflow of free radicals, elevation of intraductal pressure, damage of nerves (neuropathic pain) and compression of adjacent organs play primary role in development of pain. …”
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Enhancing Refuge Space Safety: Tape Application to Reduce Door Leakage during Fires by Hsuan-Yu Hung, Ying-Ji Chuang, Ching-Yuan Lin

“…During a fire, smoke particles and toxic emissions could infiltrate the refuge space through gaps in doors, making it a primary risk factor for casualties. …”
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Immune-Stimulatory and Therapeutic Activity of Tinospora cordifolia: Double-Edged Sword against Salmonellosis by Sultan Alsuhaibani, Masood A. Khan

“…Antibacterial activity of AETC or METC was determined by treating S. typhimurium-infected macrophages and BALB/C mice. The toxicity of AETC or METC was determined by measuring the levels of liver inflammation markers aspartate transaminase (AST) and alanine transaminase (ALT) and antioxidant enzymes. …”
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Experimental investigations of colloid-associated metal mobility in mine-impacted wetland sediment by Colleen O. Harper, Richard T. Amos

“…Metal mining operations can release toxic metals to surrounding environments where site-specific conditions control the movement of contaminants. …”
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Adsorption characteristics of cadmium onto calcite and its agricultural environmental relevance by Hyun Ho Lee

“…This strategy is a widely used chemical remediation technique aimed at reducing the bioavailability and toxicity of Cd in contaminated soils. This study comprehensively evaluated the potential of calcite for Cd remediation through geochemical analyses, including adsorption isotherms, saturation index, ion concentration changes, and X-ray diffraction (XRD) analysis. …”
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Investigation of BSA adsorption performances of metal ion attached mineral particles embedded cryogel discs by Ömür Acet

“…Natural pumice particles are non-toxic, reasonably priced and alternative adsorbents with excellent adsorption performance. …”
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Mechanisms of liver disease in patients infected with HIV by Matthew B Kaspar, Richard K Sterling

“…A thorough understanding of the mechanisms driving the development of liver disease in these patients is essential when evaluating and caring for these patients.Methods The literature regarding mechanisms of liver disease by which different disease entities may cause hepatic injury and fibrosis was reviewed and synthesised.Results A number of discrete mechanisms of injury were identified, to include: oxidative stress, mitochondrial injury, lipotoxicity, immune-mediated injury, cytotoxicity, toxic metabolite accumulation, gut microbial translocation, systemic inflammation, senescence and nodular regenerative hyperplasia. …”
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The Benefits and Detriments of Macrophages/Microglia in Models of Multiple Sclerosis by Khalil S. Rawji, V. Wee Yong

“…Such detriments include toxicity to neurons and oligodendrocyte precursor cells, release of proteases, release of inflammatory cytokines and free radicals, and recruitment and reactivation of T lymphocytes in the CNS. …”
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Amyotrophic Lateral Sclerosis, a Multisystem Pathology: Insights into the Role of TNFα by Massimo Tortarolo, Daniele Lo Coco, Pietro Veglianese, Antonio Vallarola, Maria Teresa Giordana, Gabriella Marcon, Ettore Beghi, Marco Poloni, Michael J. Strong, Anand M. Iyer, Eleonora Aronica, Caterina Bendotti

“…Our group and others have recently reported opposite involvements of TNFR1 and TNFR2 in motor neuron death. TNFR2 mediates TNFα toxic effects on these neurons presumably through the activation of MAP kinase-related pathways. …”
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Cadmium Tolerance and Detoxification Mechanisms of <i>Lentinula edodes</i>: Physiology, Subcellular Distribution, and Chemical Forms by Gaigai Chen, Bowen Han, Wene Nan, Xiaobo Dong

“…Enhanced antioxidant enzyme activities, reduced cadmium accumulation, and increased HAc-extractable cadmium with less toxicity promoted stronger cadmium tolerance and detoxification abilities in L130 compared to 1504. …”
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