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2521
Alternative 3′ UTR polyadenylation is disrupted in the rNLS8 mouse model of ALS/FTLD
Published 2025-01-01“…Together, these findings support both TDP-43 loss and toxic gain-of-function phenotypes as contributors to the neurodegeneration in rNLS8 mice, nominating its continued utility as a preclinical model for investigating mechanisms of neurodegeneration in ALS/FTLD-TDP.…”
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2522
Contribution of Lung Macrophages to the Inflammatory Responses Induced by Exposure to Air Pollutants
Published 2013-01-01“…Large population cohort studies have indicated an association between exposure to particulate matter and cardiopulmonary morbidity and mortality. The inhalation of toxic environmental particles and gases impacts the innate and adaptive defense systems of the lung. …”
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2523
Sustainable Development of Corrosion Inhibitors from Electronic Scrap: Synthesis and Electrochemical Performance
Published 2019-01-01“…Due to its high content of rare earths, the use of permanent magnets can be a sustainable alternative for the synthesis of environmentally friendly corrosion inhibitors in order to replace the use of highly toxic inhibitors, as well as the use of rare earth salts of high purity and high cost. …”
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2524
Energy and Environmental Performance of Bioethanol from Different Lignocelluloses
Published 2010-01-01“…A complete set of environmental impacts ranging from global warming potential to toxicity aspects is used. The results provide an overview on the energy efficiency and environmental performance of using fuel ethanol derived from different feedstocks in comparison with gasoline.…”
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2525
Effect of chitosan–tungsten composite coating obtained by electrophoretic deposition on the corrosion resistance of Ni–Ti alloy in physiological medium
Published 2023-08-01“…Chitosan-based composite coatings can be applied to improve the properties of Ni–Ti alloys due to their excellent properties, such as low toxicity, biocompatibility, biodegradability, and good film-forming ability. …”
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2526
Supercharged nanoadhesive through co-assembly of recombinant protein and tetrahedral DNA for corneal transplantation
Published 2025-01-01“…A major challenge is achieving rapid adhesion without introducing polymer barriers or chemical toxicity from cross-linking. To address this, we developed a novel cornea-specific nanoadhesive constructed through protein-DNA co-assembly and applied it to corneal transplantation. …”
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2527
Polycyclic Aromatic Hydrocarbons in Surface Water from Wuhai and Lingwu Sections of the Yellow River: Concentrations, Sources, and Ecological Risk
Published 2020-01-01“…The results showed that the probabilities of exceeding the chronic toxicity for 5% of the species were 28% and 32% for PAHs in surface water from Wuhai and Lingwu sections, respectively. …”
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2528
Intravenous γ Globulin for Intractable Abdominal Pain due to IgA Vasculitis
Published 2020-01-01“…We present two children with IgA vasculitis and severe abdominal pain despite corticosteroid administration, who responded promptly to intravenous γ globulin (IVIg) with complete resolution of their symptoms and review of the relevant medical literature. Given the toxicity and/or need for long-term administration of other second-line immunosuppressive therapies in corticosteroid-resistant IgA vasculitis, such as rituximab, cyclosporine, cyclophosphamide, azathioprine, or colchicine, we propose that IVIg may be a useful and safe treatment option, although randomized controlled clinical trials are needed in order to clarify its role in the treatment of abdominal pain in IgA vasculitis.…”
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2529
Dynamics of a Breast Cancer Model for Neutropenia Case due to Chemotherapy Effects
Published 2021-01-01“…Chemotherapy-induced neutropenia is one of the most common toxic effects experienced by patients and often threatens chemotherapy to use efficiency. …”
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2530
Polydiacetylene (PDA) Embedded Polymer-Based Network Structure for Biosensor Applications
Published 2025-01-01“…This color change enables the detection of biomarkers, metal ions, and toxic compounds. Moreover, the combination of PDA with polymeric structures including hydrogels further enhances the sensitivity and structural stability of PDA-based biosensors, making them reliable and effective in complex biological and environmental conditions. …”
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2531
Partial Purification and Characterization of Rhodanese from Rainbow Trout (Oncorhynchus mykiss) Liver
Published 2012-01-01“…Cyanide is one of the most toxic substances present in a wide variety of food materials that are consumed by animals. …”
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2532
Assessment of targets of antibody drug conjugates in SCLC
Published 2025-01-01“…However, significant challenges remain, including systemic toxicity, acquired resistance, and the lack of reliable biomarkers for patient selection. …”
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2533
PHYTOCHEMICAL STUDY OF CELL CULTURE JATROPHA CURCAS
Published 2024-01-01“…This plant has been reported to contain toxic compounds such as curcin and phorbol ester and its derivatives. …”
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2534
Facile synthesis of mesoporous alumina using hexadecyltrimethylammonium bromide (HTAB) as template: simplified sol‐gel approach
Published 2019-10-01“…The IC50 value obtained from cell viability study demonstrated the non‐toxic behaviour of synthesised drug‐loaded mesoporous alumina up to the tested concentration range. …”
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2535
Self-assembled nanoparticles in ocular delivery: a comprehensive review
Published 2025-01-01“…Niosomes are non-ionic surfactant-based vesicles that can encapsulate both hydrophilic and lipophilic drugs and are similar to liposomes but are more stable, less toxic, and easier to produce. Niosomes can also be surface-modified with ligands (e.g., antibodies, peptides) to target specific ocular tissues or cells and hence can improve drug penetration through the corneal and conjunctival barriers. …”
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2536
Lentinan-functionalized PBAE-G-nanodiamonds as an adjuvant to induce cGAS-STING pathway-mediated macrophage activation and immune enhancement
Published 2024-12-01“…Furthermore, LNT-PBAE-G-ND@OVA induced potent antibody response and showed no obvious toxicity in vitro and in vivo. Moreover, treatment with LNT-PBAE-G-ND@OVA was sufficient to alter the expression of genes associated with the cGAS-STING pathway, and the LNT-PBAE-G-ND@OVA induced upregulation of costimulatory molecules. …”
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2537
Chlorotoxin-functionalized mesoporous silica nanoparticles for pH-responsive paclitaxel delivery to Glioblastoma multiforme
Published 2025-01-01“…In vitro studies in the U87 GBM cell line show decreased uptake, but increased toxicity of CHX-modified nanoparticles compared to CHX-free nanoparticles. …”
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2538
Developmental and molecular effects of pure-tone sine wave exposure on early zebrafish embryo development: Implications for reproductive health
Published 2025-01-01“…This study aimed to address this gap by using zebrafish embryos at the 1-cell stage as a model to assess the toxicity of sine waves, following OECD Test No. 236. …”
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2539
Tolerance of Chemoorganotrophic Bioleaching Microorganisms to Heavy Metal and Alkaline Stresses
Published 2015-01-01“…The plate diffusion method was performed for each metal to determine the toxicity effect. Liquid batch cultures were set up for more quantitative evaluation as well as for studying the influence of basicity. …”
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2540
A review on perovskite materials for photovoltaic applications
Published 2025-04-01“…However, as the reason of their instability in its structure and the presence of toxic elements like lead element (Pb), the performance of these materials has been hindering the production and successful manufacturing of perovskite solar cells (PSCs) at the commercial level. …”
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