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2421
Foraging Activity and Trophic Spectrum of Red Ant Pogonomyrmex barbatus Smith, 1858, in Productivity-Contrasted Microenvironments
Published 2012-01-01“…Foraging strategies can be influenced by many factors such as abundance, availability, and toxicity of the resources. In arid zones, the distribution and productivity of plants also act as additional factors that affect foraging strategies. …”
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2422
Setting of import tolerances for azoxystrobin in melons and watermelons
Published 2024-12-01“…It is to be noted that the chronic consumer exposure estimated for residues in animal commodities is indicative due to data gaps related to the toxicity of livestock metabolites L1, L4, L9 and K1.…”
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2423
Acute Interstitial Nephritis in a Patient with Non-Small Cell Lung Cancer under Immunotherapy with Nivolumab
Published 2019-01-01“…These agents are associated with several “immune-mediated” adverse effects, but the reported renal toxicity of ICPIs is less well defined. We present the case of a 60-year-old man with a history of non-small cell lung cancer, who developed acute kidney injury (AKI) approximately 3.5 months after initiation of immunotherapy with nivolumab. …”
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2424
Chemogenomics for steroid hormone receptors (NR3)
Published 2025-02-01“…Here we report a chemogenomics (CG) library to reveal elusive effects of NR3 receptor modulation in phenotypic settings. 34 highly annotated and chemically diverse ligands covering all NR3 receptors were selected considering complementary modes of action and activity, selectivity and lack of toxicity. Endoplasmic reticulum stress resolving effects of N3 CG subsets in proof-of-concept application validate suitability of the set to connect phenotypic outcomes with targets and to explore NR3 receptors from a translational perspective.…”
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2425
Postinfantile Giant Cell Hepatitis with Features of Acute Severe Autoimmune Hepatitis Probably Triggered by Diclofenac in a Patient with Primary Myelofibrosis
Published 2018-01-01“…PIGCH is associated with many diseases, including drugs toxicity, viruses, and autoimmune liver diseases, with autoimmune hepatitis (AIH) being the most prevalent. …”
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2426
Carboxylic Acid Bioisosteres in Medicinal Chemistry: Synthesis and Properties
Published 2022-01-01“…Despite its common use as a key functionality in drugs, its presence in a lead molecule is often associated with poor pharmacokinetic properties and toxicity. In this literature overview, we discuss how the shortcomings of a carboxylic acid can be circumvented by replacing this functionality with bioisosteres. …”
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2427
Engineered Bacteria for Disease Diagnosis and Treatment Using Synthetic Biology
Published 2025-01-01“…These include ensuring the long‐term survival and safety of bacteria, developing new chassis microbes and gene editing techniques for non‐model strains, minimising potential toxicity, and understanding bacterial interactions with the host microbiota. …”
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2428
NK Cell and CD4+FoxP3+ Regulatory T Cell Based Therapies for Hematopoietic Stem Cell Engraftment
Published 2016-01-01“…The intensive conditioning regimens used to allow for donor hematopoietic stem cell (HSC) engraftment are often associated with severe toxicity, delayed immune reconstitution, life-threatening infections, and thus higher relapse rates. …”
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2429
Exploration on Bioflocculation of Nannochloropsis oculata Using Response Surface Methodology for Biodiesel Production
Published 2014-01-01“…The present investigation focused on the cost effective harvesting of microalga on a larger scale for biodiesel production than using toxic, ecofriendly chemical flocculants.…”
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2430
Synthesis of Alkyl α-Amino-benzylphosphinates by the Aza-Pudovik Reaction; The Preparation of the Butyl Phenyl-<i>H</i>-phosphinate Starting P-Reagent
Published 2025-01-01“…Another derivative, ethyl (α-benzylamino-benzyl-)phenylphosphinate, revealed a selective toxic activity on U266 myeloma cells.…”
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2431
Modified Granular Activated Carbon: A Carrier for the Recovery of Nickel Ions from Aqueous Wastes
Published 2004-05-01“…Granular Activated Carbon (GAC) is widely used for the removal and recovery of toxic pollutants including metals because of its low cost and high affinity towards the scavenging of metal ions. …”
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2432
The PPAR Ω Pocket: Renewed Opportunities for Drug Development
Published 2020-01-01“…The discoveries that lie at the heart of these developments have enabled the design of a new class of PPARγ ligands, capable of isolating central therapeutic effects of PPARγ modulation, while displaying markedly lower toxicities than previous generations of PPARγ ligands. …”
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2433
Kinetics and mechanism of sphalerite leaching by sodium nitrate in sulphuric acid solution
Published 2012-01-01“…Their application provides better metal recoveries and reduced emission of gaseous and toxic ageneses in the environment. The kinetics and mechanism of sphalerite leaching from complex sulphide concentrate with sulphuric acid and sodium nitrate solution at standard conditions was presented in this paper. …”
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2434
Postplanting Nutritional Augmentation of Jeffrey Pine Seedlings on an Infertile Sierran Site
Published 2011-01-01“…Foliar analysis revealed that improved N nutrition was probably critical in the favorable growth responses to fertilization, that of P was a likely contributor, and amelioration of potential Mn toxicity may have assumed an accessory role.…”
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2435
Scorpion Venom and the Inflammatory Response
Published 2010-01-01“…Scorpion venoms consist of a complex of several toxins that exhibit a wide range of biological properties and actions, as well as chemical compositions, toxicity, and pharmacokinetic and pharmacodynamic characteristics. …”
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2436
Positive sentiment and expertise predict the diffusion of archaeological content on social media
Published 2025-01-01“…Our results align with other studies on the spread of misinformation and “toxic” behaviour on social media, showing that the sharing of negative and hostile content by a vocal minority of users is mediated by other factors pertaining to the context of the communication. …”
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2437
On Nonlinear Simulation Methods and Tools for Evaluating the Performance of Ships and Offshore Structures in Waves
Published 2012-01-01“…This capability supports the increased demand of this type of tools for the proper selection of engine/propulsion systems accounting for ship’s performance in realistic sea conditions, or when optimizing ship’s sailing route for minimum fuel consumption and toxic gas emissions.…”
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2438
Opening Doors
Published 2025-01-01“…Drawing from insights in fan studies, this article explores toxic fan practices within political fandom, as highlighted by Petersen et al. (2023) and Le Clue (2024). …”
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2439
Interplay between porin deficiency, fitness, and virulence in carbapenem-non-susceptible Pseudomonas aeruginosa and Enterobacteriaceae.
Published 2025-02-01“…Porins are outer membrane proteins, which play a key role in the bacterial permeability to allow nutrients to enter and toxic waste to leave. However, these channels are also "Achilles' heel" of bacteria as antibiotics can also pass through them to reach their target and kill the bacteria. …”
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2440
Midregion PTHrP and Human Breast Cancer Cells
Published 2010-01-01“…The midregion PTHrP domain (38-94)-amide was found to restrain growth and invasion in vitro of some breast cancer cell lines, causing striking toxicity and accelerating death; the most responsive being MDA-MB231, whose tumorigenesis was also attenuated in vivo. …”
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