Safety of Cyclophosphamide Therapy in Autoimmune Rheumatic Diseases by Ramaswamy Subramanian, Himanshu Pathak, Vinod Ravindran

“…However, its use may be limited by the toxicities including its adverse effects on gonads in the childbearing age group, severe infections, hemorrhagic cystitis, and malignancies associated with prolonged usage. …”
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Staying Optimistic: The Trials and Tribulations of Leibnizian Optimism by Lloyd Strickland

“…As we shall see, while Leibniz’s doctrine did win a good number of adherents in the 1720s and 1730s, especially in Germany, support for it had largely dried up by the mid-1740s; moreover, while opponents of Leibniz’s doctrine were few and far between in the 1710s and 1720s, they became increasing vocal in the 1730s and afterwards, between them producing an array of objections that served to make Leibnizian optimism both philosophically and theologically toxic years before the Lisbon earthquake struck.…”
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Sublethal Effects of Diesel on Total Protein Levels and Cholesterol in <i>Tympanotonus Fuscatus</i> by OS Edori, IB Nwoke, ES Edori

“…This study showed that exposure of periwinkles (Tympanotonus fuscatus) to diesel toxicity could cause deleterious effects or changes in the organism biochemistry.…”
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Rare coexistence of spinal muscular atrophy with membranous nephropathy – A clinical conundrum with management dilemma by Gerry G. Mathew, Jayaprakash Varadharajan, Sreedhar Sailapathy, R. Kalpana

“…This case report describes the management dilemma in membranous nephropathy with SMA due to the risk of toxic myopathies associated with tacrolimus and steroids.…”
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Adsorption Characteristics of Acid Orange 10 from Aqueous Solutions onto Montmorillonite Clay by Manpreet Kaur, Monika Datta

“…Azo dyes have been identified as the most toxic of all dyes since they may be converted into potentially carcinogenic and/or mutagenic amines as a result of the reductive cleavage of the azo linkages after being released into the aquatic environment. …”
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VDB Entropy Measures and Irregularity-Based Indices for the Rectangular Kekulene System by Weidong Zhao, K. Julietraja, P. Venugopal, Xiujun Zhang

“…Irregularity indices are numerical parameters that quantify the irregularity of a molecular graph and are used to predict some of the chemical properties, including boiling points, resistance, enthalpy of vaporization, entropy, melting points, and toxicity. This study aims to determine analytical expressions for the VDB entropy and irregularity-based indices in the rectangular Kekulene system.…”
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Sublethal Effects of Diesel on Total Protein Levels and Cholesterol in <i>Tympanotonus Fuscatus</i> by OS Edori, IB Nwoke, ES Edori

“…This study showed that exposure of periwinkles (Tympanotonus fuscatus) to diesel toxicity could cause deleterious effects or changes in the organism biochemistry.…”
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Contaminants in the Urban Environment: Pharmaceuticals and Personal Care Products (PPCPs)—Part 1 by Yun-Ya Yang, Gurpal S. Toor

“…This series is intended to give state and local government officials, soil scientists, consulting engineers, extension agents, and citizens (1) a basic understanding of the occurrence, toxic effects, and source of various contaminants in the environment and (2) guidance on ways to protect human and environmental health. …”
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A Beginner’s Guide to Water Management—Fish Kills by Florida LAKEWATCH

“… In an effort to alleviate concerns voiced by the general public, the Florida LAKEWATCH (FLW) program published this 16-page booklet that discusses five of the most common natural causes of fish kills including: low dissolved oxygen; spawning fatalities; mortality due to cold temperatures; diseases and parasites; and toxic algae blooms. Human-induced fish kills are also covered along with a section on fish stress—a component of virtually every fish kill situation. …”
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Blowout Accident Impact Analysis Method for the Siting of Offshore Floating Nuclear Power Plant in Offshore Oil Fields by Zhigang Lan

“…The impacts of blowout accident in offshore oil field on OFNPP are comprehensively analyzed, including injection combustion and spilled oil combustion induced by well blowout, drifting and explosion of deflagration vapor clouds formed by well blowouts, seawater pollution caused by blowout oil spills, the toxic gas cloud caused by well blowout, and the impact of mobile fire source formed by a burning oil spill on OFNPP at sea. …”
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A Comprehensive Review on the Chemical Composition and Pharmacological Activities of Acacia catechu (L.f.) Willd. by Bikash Adhikari, Babita Aryal, Bibek Raj Bhattarai

“…Although the metabolites from the plant are reported with diverse pharmacological applications, there is little information in regards to toxicity and clinical trials on bioactive compounds of this plant. …”
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Recent advances in the characterization of genetically defined neurons that regulate internal‐state‐dependent taste modification in mice by Ken‐ichiro Nakajima

“…While some tastes are intrinsically appetitive, such as sweet, which is elicited from high‐calorie nutrients, the other tastes, such as sour and bitter, are aversive and elicited by toxic substances. In mice, taste signals are relayed by multiple regions of the brain, including the nucleus of the solitary tract, and the parabrachial nucleus (PBN) of the pons, before reaching the gustatory cortex via the gustatory thalamus. …”
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Carcinogenic and Genotoxicity of some PAHs in commonly consumed smoked fish (<i>Parachanna obscura</i> and <i>Ethmalosa fimbriata) </i> by N.O. Erhunmwunse, S.A. Ekaye

“…Risk assessment conducted using benzo(a)pyrene carcinogenic and mutagenic toxicity equivalent factor (TEQ & MEQ) showed slight to high risk (7.44 x10-5 -1.95 x10-3 ) and exceeded the USEPA guideline (1.0 x 10-5 ) for potential Cancer. …”
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A Beginner’s Guide to Water Management—Fish Kills by Florida LAKEWATCH

“… In an effort to alleviate concerns voiced by the general public, the Florida LAKEWATCH (FLW) program published this 16-page booklet that discusses five of the most common natural causes of fish kills including: low dissolved oxygen; spawning fatalities; mortality due to cold temperatures; diseases and parasites; and toxic algae blooms. Human-induced fish kills are also covered along with a section on fish stress—a component of virtually every fish kill situation. …”
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The N17 domain of huntingtin as a multifaceted player in Huntington’s disease by Hyunju Cho

“…Diverse post-translational modifications (PTMs) in the N17 domain alter the aggregation state, thus modulating the cellular toxicity of mHttex1. Furthermore, the N17 domain serves as a nuclear export signal (NES) and mediates the cytoplasmic localization of mHttex1. …”
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Functionalized Bioadsorbent Application on Methylene Blue Removal From Wastewater—A Review by Jean B. Batchamen Mougnol, Sudesh Rathilal

“…Various industries such as petroleum, pharmaceuticals, textiles and households have been responsible for releasing MB into the environment. Its toxicity and acute health implications for animals and humans have suggested several technological applications for its removal. …”
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Privatized Futures, Climate Control, and Resistance in Recent Scottish Dystopian Fiction by Peter Clandfield

“…After discussing Alasdair Gray’s 1982, Janine (1984) as an influential confrontation with the increasingly toxic military-industrial state of 1980s Britain, the essay interprets Matthew Fitt’s But n Ben A-Go-Go (2000), John Aberdein’s Strip the Willow (2009), and the multiple-author graphic novel IDP: 2043 (2014), edited by Denise Mina, as what Umberto Eco calls “novels of anticipation,” or warnings of the undesirable eventualities that present tendencies may bring about. …”
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Design and Construction of an Electronic Mosquito Repellant. by Kwesiga, Isaac

“…Coils, mats can produce toxic fumes when heated and cause breathing trouble whereas liquid vaporizers can also produce fumes when heated. …”
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Radiotherapy(R) Integration(I) Strategy for Small(S)-Cell Lung Cancer in Extensive(E) Stage (RISE) with up to 10 metastases- a study protocol of a randomized phase II trial by Łukasz Kuncman, Jacek Fijuth, Damian Tworek, Ewa Sierko, Paweł Cisek, Michał Masłowski, Maja Lisik-Habib, Magdalena Orzechowska, Katarzyna Galwas-Kliber, Adam Antczak, Izabela Chmielewska, Barbara Ziółkowska, Marta Kurczewska-Michalak, Wojciech Kuźnicki, Nina Jędrzejczak, Kinga Ranoszek, Mateusz Bilski

“…Secondary endpoints are OS, treatment toxicity (frequency of G3 toxicity according to CTCAE v.5.0), area of progression (primary tumor localization/new lesions), Overall response rate (ORR), and the response rate in non-irradiated lesions. …”
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Proton therapy versus conventional radiotherapy for the treatment of cavernous sinus benign meningioma, a randomized controlled phase III study protocol (COG-PROTON-01) by Paul Lesueur, Benedicte Clarisse, Justine Lequesne, Idlir Licaj, Loic Feuvret, Dinu Stefan, Damien Ricard, Georges Noel, Jacques Balosso, Marie Lange, Aurelie Capel, Isabelle Durand-Zaleski, Marie Castera, Berenice Legrand, Nicolas Goliot, Camille Hedou, Jean Michel Grellard, Samuel Valable

“…Methods COG-PROTON-01 is the first worldwide randomized phase III prospective study evaluating long-term toxicity of these two irradiation modalities (PRT and XRT)for the treatment of cavernous sinus meningioma. …”
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