-
2301
Integrating melt electrospinning writing and microfluidics to engineer a human cardiac microenvironment for high-fidelity drug screening
Published 2025-03-01“…Taken together, these results highlight the ability of our myocardial microarray platform to accurately reflect clinical behaviour, underscoring its potential as a powerful pre-clinical tool for assessing drug response and toxicity.…”
Get full text
Article -
2302
Influence of Heat Treatment on Biocorrosion and Hemocompatibility of Biodegradable Mg-35Zn-3Ca Alloy
Published 2015-01-01“…The hemolysis value was ≤5% in all groups, indicating no toxicity during short-term blood reaction.…”
Get full text
Article -
2303
Quantum dot nanomaterials: Empowering advances in optoelectronic devices
Published 2025-03-01“…Nevertheless, the broad implementation of these technologies is impeded by problems such as exorbitant production costs, probable toxicity, and environmental instability. Novel synthesis strategies, such as nonorganometallic approaches and microwave-based procedures, are addressing these problems by strengthening safety, reducing expenses, and improving the photostability of quantum dots. …”
Get full text
Article -
2304
S-Glutathionylation of Protein Disulfide Isomerase Regulates Estrogen Receptor α Stability and Function
Published 2012-01-01“…Expression of an S-glutathionylation refractory PDI mutant diminishes the toxic effects of PABA/NO. Thus, redox regulation of PDI causes its S-glutathionylation, thereby mediating cell death through activation of the UPR and abrogation of ERα stability and signaling.…”
Get full text
Article -
2305
Cancer therapy-related interstitial lung disease
Published 2025-02-01“…The recognition of pulmonary toxicity related to cancer therapy has become increasingly critical, for which interstitial lung disease (ILD) is a common cause of mortality. …”
Get full text
Article -
2306
Fundus Autofluorescence and Clinical Applications
Published 2021-07-01“…Emerging clinical evidence has demonstrated the usefulness of FAF in diagnosis and management of an increasing number of chorioretinal conditions, such as age-related macular degeneration, central serous chorioretinopathy, retinal drug toxicities, and inherited retinal degenerations such as retinitis pigmentosa and Stargardt disease. …”
Get full text
Article -
2307
Adulteration of the Herbal Weight Loss Products by the Illegal Addition of Synthetic Antiobesity Medications: A Pilot Study
Published 2021-01-01“…Since apothecaries have advised consumers to take at least two capsules a day, it seems that the blood concentration of sibutramine will likely rise beyond the therapeutic concentration and become toxic. Therefore, the usage of such products could pose serious risks to consumers’ health.…”
Get full text
Article -
2308
Facteurs alimentaires et environnementaux de risque du cancer du rhino-pharynx dans la région de Marrakech
Published 2001-11-01“…Women are affected earlier than men: a peak has been observed between the ages of 20 and 30 in women and another between the ages of 40 and 50 in men.The analysis of a questionnaire submitted to 32 individuals affected by the NPC and to a check sample of 48 showed a statistically significant relationship between the NPC and some nutritional and environmental factors: consumption of smen (fermented butter), khlii (dried, salted spicy baked meat preserved in a mixt of smelted beef grease) and alcohol; practising of agriculture and cattle breeding; contact with toxic substances.…”
Get full text
Article -
2309
The influence of the ultrasonic field on the efficiency of leachate treatment in the SBR reactor
Published 2025-01-01“…The study showed that sonication increases biodegradability and reduces their toxicity. The use of pre-sonication before biological treatment improved the degree of removal of the tested parameters by about 10 %. …”
Get full text
Article -
2310
Contaminants in the Urban Environment: Pharmaceuticals and Personal Care Products (PPCPs)—Part 2
Published 2015-05-01“…This series is intended to give state and local government officials, soil scientists, consulting engineers, extension agents, and citizens (1) a basic understanding of the occurrence, toxic effects, and source of various contaminants in the environment and (2) guidance on ways to protect human and environmental health. …”
Get full text
Article -
2311
Antioxidant Functions of the Aryl Hydrocarbon Receptor
Published 2016-01-01“…It is generally accepted that the toxic responses of polycyclic aromatic hydrocarbons, dioxins, and structurally related compounds are mediated by activation of the AhR. …”
Get full text
Article -
2312
Type 2 Inflammatory Responses in Autoimmune Demyelination of the Central Nervous System: Recent Advances
Published 2019-01-01“…However, growing evidence suggests that cells and mediators typically associated with type 2 inflammation are involved in several physiopathological conditions, such as defense against toxic substances, anticancer immunity, and autoimmune diseases. …”
Get full text
Article -
2313
The Management of Classical Hodgkin's Lymphoma: Past, Present, and Future
Published 2011-01-01“…In addition, the young age of many Hodgkin's patients forces difficult decisions in balancing the benefit of early disease control against the survival disadvantage of late toxicity. In this article we aim to summarise past trials, define the current standard of care and appraise future developments in the management of CHL.…”
Get full text
Article -
2314
Retroperitoneal Lymph Node Dissection as Primary Treatment for Metastatic Seminoma
Published 2018-01-01“…External beam radiation therapy and systemic chemotherapy are established treatments for seminoma; however, they are associated with late toxicities such as cardiovascular disease, insulin resistance, and secondary malignancy. …”
Get full text
Article -
2315
DRINKING WATER SUPPLY UNDER THE CONDITIONS OF MASS DEVELOPMENT OF BLUE-GREEN ALGAE IN RESERVOIRS
Published 2021-04-01“…During the period of mass development of cyanobacteria, the quality of water in the reservoir deteriorates in terms of a number of indicators, including smell, taste, and content of organic and toxic substances. Among the wide range of cyanoxins, the greatest danger to the population is microcystin-LR, the concentration of which in drinking water should not exceed 1 μg/dm3. …”
Article -
2316
Role of Lipoic Acid in Testosterone Production in Males
Published 2025-01-01“…In summary, lipoic acid consistently restores testosterone levels, offering promise as an intervention in testicular health, especially in cases of testicular toxicity caused by various harmful agents. Its mechanisms encompass nitric oxide enhancement, fortification of testicular antioxidants, elevation of luteinizing hormone, enhancement of steroidogenesis, and the maintenance of energy production. …”
Article -
2317
Contaminants in the Urban Environment: Pharmaceuticals and Personal Care Products (PPCPs)—Part 2
Published 2015-05-01“…This series is intended to give state and local government officials, soil scientists, consulting engineers, extension agents, and citizens (1) a basic understanding of the occurrence, toxic effects, and source of various contaminants in the environment and (2) guidance on ways to protect human and environmental health. …”
Get full text
Article -
2318
EFFECTIVENESS OF INNOVATIVE SOLUTIONS IN MULTICULTURAL MANAGEMENT BASED ON A BIG PHARMA COMPANY CASE STUDY
Published 2024-12-01“…If not, it can lead to conflicts and a toxic work environment.…”
Get full text
Article -
2319
Fabric-based patchwork on shoes through ultrasonic welding
Published 2025-02-01“…Decorative or functional patches on shoes are typically attached using stitching or adhesives, both of which present challenges: stitches often fail due to wear and tear, while adhesives involve toxic materials that are environmentally harmful. …”
Get full text
Article -
2320
Contaminants in the Urban Environment: Pharmaceuticals and Personal Care Products (PPCPs)—Part 1
Published 2015-05-01“…This series is intended to give state and local government officials, soil scientists, consulting engineers, extension agents, and citizens (1) a basic understanding of the occurrence, toxic effects, and source of various contaminants in the environment and (2) guidance on ways to protect human and environmental health. …”
Get full text
Article