Ice Hockey Lung – A Case of Mass Nitrogen Dioxide Poisoning in The Czech Republic by Kristian Brat, Zdenek Merta, Marek Plutinsky, Jana Skrickova, Miroslav Stanek Ing

“…Nitrogen dioxide (NO2) is a toxic gas, a product of combustion in malfunctioning ice-resurfacing machines. …”
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Genetic factors for breast carcinogenesis by Pedro Enrique Miguel-Soca, Ivis Argüelles González, Marisol Peña González

“…To the susceptibility of cancer due to genes as BRCA1 and BCRA2, the effect of factors associated to environment, life style and toxic habits are added, these determine a complex interrelation genes-environment which imply an activation of oncogenes and inactivation of tumour suppressors. …”
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New Approach Methodologies: Physiological responses of daphnids to pharmaceutical mixtures by Emma Rowan, Anne Leung, Katie O’Rourke, Xiaofei Yin, Lorraine Brennan, Konstantinos Grintzalis

“…The pharmaceutical cocktail comprised of representatives of commonly encountered pharmaceuticals and specifically diclofenac, metformin, gabapentin, amoxicillin, trimethoprim, and erythromycin. Combining toxicity, phenotypic and molecular endpoints, results showed differences in mortality, feeding, key enzyme activities and metabolic perturbations, thus supporting a distinct pattern in physiological responses of daphnids that could be used to monitor and predict pollution early.…”
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Research Progress on the Preparation and Modification of Magnetic Nanomaterials and Their Application in Mycotoxin Detection and Removal by LÜ Jianxin, GUO Mengyue, ZHANG Huiru, KONG Dandan, LUO Jiaoyang, YANG Meihua

“…Mycotoxins are toxic small-molecular-mass compounds produced naturally by toxigenic fungi. …”
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Plasmid Gene Therapy for Monogenic Disorders: Challenges and Perspectives by Marco A. Luís, Marcelo A. D. Goes, Fátima Milhano Santos, Joana Mesquita, Paulo Tavares-Ratado, Cândida Teixeira Tomaz

“…However, despite advancements in gene manipulation tools and delivery systems, several challenges remain unresolved, including inefficient delivery, lack of sustained expression, immunogenicity, toxicity, capacity limitations, genomic integration risks, and limited tissue specificity. …”
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Fungal- and Algal-Derived Synthesis of Various Nanoparticles and Their Applications by Anugrah Michael, Aniket Singh, Arpita Roy, Md. Rabiul Islam

“…Most traditional methods to generate nanoparticles have certain limitations, like the toxicity of precursor materials, the need for high-temperature management, and the high cost of synthesis, which ultimately hinders their utility in sectors. …”
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Intergraded Applied Methodology for the Treatment of Heavy Polluted Waste Waters from Olive Oil Industries by Antonis A. Zorpas, Vassilis J. Inglezakis

“…The cocomposting of the olive oil solid residue (OOSR) and the treated wastewaters (with Fenton) from the olive oil production process with the application of reed beds has been studied as an integrated method for the treatment of wastewater containing high organic and toxic pollutants under warm climate conditions. The experimental results indicated that the olive mill wastewater (OMW) is detoxified at the end of the Fenton process. …”
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Mineral Element Contents in Commercially Valuable Fish Species in Spain by Ana Rivas, Luis Peña-Rivas, Eduardo Ortega, Concepción López-Martínez, Fátima Olea-Serrano, Maria Luisa Lorenzo

“…In conclusion, metal contents in the fish species analyzed are acceptable for human consumption from a nutritional and toxicity point of view.…”
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Life Threatening Severe QTc Prolongation in Patient with Systemic Lupus Erythematosus due to Hydroxychloroquine by John P. O’Laughlin, Parag H. Mehta, Brian C. Wong

“…The patient was noted to have mild prolongation of the QT interval on electrocardiogram prior to initiation of hydroxychloroquine therapy which was exacerbated by its use and may have been caused due to toxicity from underlying renal failure.…”
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Zinc Metalloproteinases and Amyloid Beta-Peptide Metabolism: The Positive Side of Proteolysis in Alzheimer's Disease by Mallory Gough, Catherine Parr-Sturgess, Edward Parkin

“…Alzheimer's disease is a neurodegenerative condition characterized by an accumulation of toxic amyloid beta- (A𝛽-)peptides in the brain causing progressive neuronal death. …”
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Treatment of Severe Acetaminophen–Induced Hepatocellular Injury with Prostaglandin E: Two Case Reports by Marina Khatchatourian, Hillar Vellend

“…Acetaminophen hepatotoxicity is mediated by a toxic reactive metabolite formed from the parent compound by the cytochrome P450 mixed-function oxidase system of the hepatocyte. …”
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Unilateral Optic Neuritis: A Rare Complication after Measles-Mumps-Rubella Vaccination in a 30-Year-Old Woman by Chiara De Giacinto, Elvira Guaglione, Pia E. Leon, Rossella D’Aloisio, Odilla Vattovani, Giuseppe Ravalico, Daniele Tognetto

“…Optic neuritis is one of the rare complications associated with the mumps, measles, and rubella vaccine. It may be a toxic reaction to the nonviral component of the vaccine, but the exact etiology is unknown. …”
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The Need for Inducing Tolerance in Vascularized Composite Allotransplantation by Kadiyala V. Ravindra, Hong Xu, Larry D. Bozulic, David D. Song, Suzanne T. Ildstad

“…In order to optimize VCA outcomes, translational studies are needed to develop less toxic immunosuppression and possibly achieve donor-specific tolerance. …”
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TLC densitometric method for screening of lycopsamine in comfrey root (Symphytum officinale L.) extracts using retrorsine as a reference compound by Janeš Damjan, Kreft Samo

“…Due to severe toxicity of pyrrolizidine alkaloids, their quantification in medicinal products is very important. …”
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Recurrence of Chronic Myeloid Leukemia during Pregnancy Subsequently Achieving Complete Medical Remission by Sasha Mikhael, Ashlee Pascoe, Joseph Prezzato

“…Much controversy exists regarding continuation versus discontinuation of its use in pregnancy with some studies suggesting safety of TKIs before and during pregnancy and others reporting toxicity and adverse outcomes. TKIs have become a well-established treatment option for CML, significantly improving prognosis, and yet have been reported to be fetotoxic. …”
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Application of adoptive cell therapy in malignant melanoma by Qianrong Hu, Jiangying Xuan, Lu Wang, Kangjie Shen, Zixu Gao, Yuhong Zhou, Chuanyuan Wei, Jianying Gu

“…Thus, adoptive cell therapy (ACT), employing immune cells with specific tumor-recognizing receptors, has emerged as a promising therapeutic approach to display on-tumor toxicity. This review discusses the application, efficacy, limitations, as well as future prospects of four commonly utilized approaches -including tumor-infiltrating lymphocytes, chimeric antigen receptor (CAR) T cell, engineered T-cell receptor T cells, and chimeric antigen receptor NK cells- in the context of malignant melanoma.…”
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Alteration of Energy Substrates and ROS Production in Diabetic Cardiomyopathy by O. Lorenzo, E. Ramírez, B. Picatoste, J. Egido, J. Tuñón

“…In addition, the oxidation of fatty acids can saturate and cause their deposition in the cytosol, where they deviate to induce toxic metabolites or gene expression by nuclear-receptor interaction. …”
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Production of Biosurfactants by Ascomycetes by Michele Alves Sanches, Isabella Galvão Luzeiro, Ana Cláudia Alves Cortez, Érica Simplício de Souza, Patrícia Melchionna Albuquerque, Harish Kumar Chopra, João Vicente Braga de Souza

“…However, these surfactants are usually highly toxic and are poorly degraded by microorganisms. …”
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Ammonium Ion Exchanged Zeolite for Laser Desorption/Ionization Mass Spectrometry of Phosphorylated Peptides by Mengrui Yang, Tatsuya Fujino

“…CHCA adsorbed to NH4+-type ZSM5 zeolite (CHCA/NH4ZSM5) was used to measure atropine and aconitine, two toxic alkaloids in plants. In addition, CHCA/NH4ZSM5 enabled us to detect phosphorylated peptides; peaks of the protonated peptides had higher intensities than the peaks observed using CHCA only.…”
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Venom of the Endoparasitoid Wasp Pteromalus puparum: An Overview by Jia-Ying Zhu, Gong-Yin Ye, Cui Hu

“…Even great achievements have been made, further research is required to uncover the sophisticated bioactivity of the venom and isolate more novel toxic peptides/proteins.…”
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