Nanocomposite magnetic hydrogel with dual anisotropic properties induces osteogenesis through the NOTCH-dependent pathways by Shijia Tang, Yue Yan, Xiaoli Lu, Peng Wang, Xueqin Xu, Ke Hu, Sen Yan, Zhaobin Guo, Xiao Han, Feimin Zhang, Ning Gu

“…The utilization of physical factors to promote the osteogenic differentiation of stem cells has been established as a new strategy for developing bone tissue engineering scaffolds. In this context, scaffolds with multiscale anisotropy are considered to possess biomimetic properties, which are advantageous for their biological performance. …”
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Restoration of a Critical Mandibular Bone Defect Using Human Alveolar Bone-Derived Stem Cells and Porous Nano-HA/Collagen/PLA Scaffold by Xing Wang, Helin Xing, Guilan Zhang, Xia Wu, Xuan Zou, Lin Feng, Dongsheng Wang, Meng Li, Jing Zhao, Jianwei Du, Yan Lv, Lingling E, Hongchen Liu

“…However, the feasibility of tissue engineering using human craniofacial BMSCs was unclear. …”
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Exploring nanocomposite materials in clinical dermatology: Innovations for treating skin diseases by Sandipan Dasgupta, Subhasundar Maji, Sanjay Dey, Moitreyee Chattopadhyay, Ananya Chanda, Satarupa Acharjee, Kousik Santra, Kazi Asraf Ali

“…These advancements show significant potential in treating various skin conditions, including wounds, infections, cancer, and tissue engineering. Nanocomposites also excel in antimicrobial therapies, promoting wound healing, combating bacterial and fungal infections, and targeting cancer cells in skin carcinoma treatments. …”
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Enhanced bone regeneration using sodium alginate and polyvinyl alcohol incorporating TiO2 nanoparticles composite film for orthopedic application by Guoying Zhang, Xunkai Hou, Zhen Geng, Mahani Yusoff, Nur Adibah Roslan, Mohd Hasmizam Razali

“…Among these, the PVA + SA@10 wt%TiO2NPs nanocomposite film exhibited exceptional bioactivity and antibacterial properties, positioning it as a promising candidate for bone tissue engineering. Notably, hydroxyapatite (HA) formation was observed within 7 days of immersing the nanocomposite film in simulated body fluid (SBF), effectively mimicking natural bone mineralization. …”
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Development and Optimization of Nano-Hydroxyapatite Encapsulating Tocotrienol-Rich Fraction Formulation Using Response Surface Methodology by Anis Syauqina Mohd Zaffarin, Shiow-Fern Ng, Min Hwei Ng, Haniza Hassan, Ekram Alias

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Fabrication of Core-Shell PEI/pBMP2-PLGA Electrospun Scaffold for Gene Delivery to Periodontal Ligament Stem Cells by Qiao Xie, Lie-ni Jia, Hong-yu Xu, Xiang-gang Hu, Wei Wang, Jun Jia

“…Bone tissue engineering is the most promising technology for enhancing bone regeneration. …”
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Comparison of Osteogenesis between Adipose-Derived Mesenchymal Stem Cells and Their Sheets on Poly-ε-Caprolactone/β-Tricalcium Phosphate Composite Scaffolds in Canine Bone Defects... by Yongsun Kim, Seung Hoon Lee, Byung-jae Kang, Wan Hee Kim, Hui-suk Yun, Oh-kyeong Kweon

“…These results suggest that the PCL/β-TCP/OCS composite has potential clinical applications in bone regeneration and can be used as an alternative treatment modality in bone tissue engineering.…”
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The miRNA‐mRNA Regulatory Network in Human Hepatocellular Carcinoma by Transcriptomic Analysis From GEO by Razieh Heidari, Vahideh Assadollahi, Seyedeh Negar Marashi, Fatemeh Elahian, Seyed Abbas Mirzaei

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Evaluation of the immunological functions of placental alkaline phosphatase in vivo using ALPP transgenic mice by Tse-Ching Chen, Kwai-Fong Ng, Ning Chen, Yi-Ling Pan, Chun-An Cheng, Hsiao-Chun Wu, Yi-Jen Hsueh, Nien-Yi Chiang, Hsi-Hsien Lin, Hsi-Hsien Lin, Hsi-Hsien Lin, Hsi-Hsien Lin

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Innovative Hydrogel Design: Tailoring Immunomodulation for Optimal Chronic Wound Recovery by Chun‐Mei Lai, Wei‐Ji Chen, Yuan Qin, Di Xu, Yue‐Kun Lai, Shao‐Hua He

“…Abstract Despite significant progress in tissue engineering, the full regeneration of chronic wounds persists as a major challenge, with the immune response to tissue damage being a key determinant of the healing process's quality and duration. …”
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The Human Mesenchymal Stromal Cell-Derived Osteocyte Capacity to Modulate Dendritic Cell Functions Is Strictly Dependent on the Culture System by Sara Trabanelli, Federico La Manna, Marco Romano, Valentina Salvestrini, Michele Cavo, Marilena Ciciarello, Roberto M. Lemoli, Antonio Curti

“…This finding may have relevant implications for the design of cell-based tissue-engineering strategies.…”
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Innovative Zein-derived inks: Towards sustainable 3D printing solutions by Derniza-Elena Cozorici, Erika Blanzeanu, Ionut-Cristian Radu, Marian Nicolae Verziu, Cristina Stavarache, Minodora Marin, Rafael Luque, Catalin Zaharia

“…These findings expand the limited research on zein as a 3D-printable material, showcasing its potential for sustainable manufacturing and soft tissue engineering.…”
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The effect of calf muscular vein thrombosis on the prognosis within one year postoperatively of geriatric hip fracture patients: a propensity score-matched analysis by Jiabao Jiang, Fei Xing, Rong Luo, Zhao Chen, Hao Liu, Zhou Xiang, Xin Duan

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Optimal Pore Size of Honeycomb Polylactic Acid Films for In Vitro Cartilage Formation by Synovial Mesenchymal Stem Cells by Misaki Yagi, Mitsuru Mizuno, Ryota Fujisawa, Hisako Katano, Kentaro Endo, Nobutake Ozeki, Yuriko Sakamaki, Hideyuki Koga, Ichiro Sekiya

“…Background. Tissue engineering of cartilage requires the selection of an appropriate artificial scaffold. …”
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Differential regulation of apoptosis-related genes during long-term culture and differentiation of canine adipose-derived stem cells - a functional bioinformatical analysis by Maurycy Jankowski, Maurycy Jankowski, Maurycy Jankowski, Katarzyna Stefańska, Michał Suchodolski, Claudia Dompe, Claudia Dompe, Grzegorz Wąsiatycz, Bartosz Kempisty, Bartosz Kempisty, Bartosz Kempisty, Bartosz Kempisty, Michał Nowicki, Magdalena Roszak

“…A total of 17793 genes were detected and GO enrichment analysis was performed on the differentially expressed genes to identify significantly up- and downregulated Biological Process (BP) GO terms across each comparison.ResultsThe upregulation of apoptosis-regulating genes and genes related to circulatory system development suggest an induction of these processes, while the downregulation of neurogenesis and gliogenesis genes points to reciprocal regulation during osteogenic differentiation of canine ADSCs.DiscussionThese findings underscore the potential of ADSCs in bone regeneration and offer valuable insights for advancing tissue engineering, however further studies, including proteomic analyses, are needed to confirm these patterns and their biological significance.…”
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Efficacy Study of Carrageenan as an Alternative Infused Material (Filler) in Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) Porous 3D Scaffold by Nor Syamimi Che Johari, Syazwan Aizad, Saiful Irwan Zubairi

“…In conclusion, the usage of carrageenan as a composite material exhibits its great potential to be used in tissue engineering application and 3D cell culture model.…”
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In Vivo and In Vitro Study of a Polylactide-Fiber-Reinforced β-Tricalcium Phosphate Composite Cage in an Ovine Anterior Cervical Intercorporal Fusion Model by Janek Frantzén, Aliisa Pälli, Esa Kotilainen, Harri Heino, Bettina Mannerström, Heini Huhtala, Hannu Kuokkanen, George K. Sándor, Kari Leino, Matias Röyttä, Riitta Parkkola, Riitta Suuronen, Susanna Miettinen, Hannu T. Aro, Suvi Haimi

“…In conclusion, the composite implant material can be applied with hASCs for tissue engineering but not be evaluated in vivo with sheep.…”
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A Framework for Promoting Passive Breast Cancer Monitoring: Deep Learning as an Interpretation Tool for Breast Thermograms by Mohamad Firouzmand, Keivan Majidzadeh, Maryam Jafari, Shahpar Haghighat, Rezvan Esmaeili, Leila Moradi, Nima Misaghi, Mahsa Ensafi, Fatemeh Batmanghelich, Mohammadreza Keyvanpour, Seyed Vahab Shojaedini

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Differentiation Potential of Early- and Late-Passage Adipose-Derived Mesenchymal Stem Cells Cultured under Hypoxia and Normoxia by Ashley G. Zhao, Kiran Shah, Julien Freitag, Brett Cromer, Huseyin Sumer

“…Therefore, any of these culture conditions could be used when scaling up MSCs in bioreactors for allogeneic clinical applications or tissue engineering for the treatment of joint and bone diseases such as osteoarthritis.…”
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hCTLA4-Gene-Modified Human Bone Marrow-Derived Mesenchymal Stem Cells (hBMMSCs) Maintain POSTN Secretion to Enhance the Migration Capability of Allogeneic hBMMSCs through the Integ... by Lei Song, Fei Zhang, Rui Zhou, Jun Xiao, Lei He, Fei Dai

“…Cytotoxic T-lymphocyte-associated protein 4- (CTLA4-) modified human bone marrow-derived mesenchymal stem cells (hBMMSCs) might be promising seed cells for bone tissue engineering. However, the underlying mechanism is not clear. …”
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