A deep learning-based ADRPPA algorithm for the prediction of diabetic retinopathy progression by Victoria Y. Wang, Men-Tzung Lo, Ta-Ching Chen, Chu-Hsuan Huang, Adam Huang, Pa-Chun Wang

“…Furthermore, DR and microaneurysm scores generated from low- and high-resolution fundus images, respectively, can help identify patients at a high risk of NRDR, facilitating timely treatment.…”
Get full text

Development and evaluation of optimized PCR and indirect ELISA for the detection of Morganella morganii in dairy cows by Meihua Zhang, Jiayi Li, Jianfeng Xue, Huiling Xu, Muzi Li, Yibo Xia, Changxi Qi, Pu Zhang, Yongxia Liu, Jianzhu Liu

“…Together, these tools enable timely intervention, contributing to improved livestock health management and mitigating the negative impacts of M. morganii on dairy cow productivity. …”
Get full text

Therapeutic effectiveness of three commercial anthelmintics against strongylids in buffalo calves (Bubalus bubalis) by David Uzcátegui, Víctor Gutiérrez, María Rodríguez, Andrea González, Alfredo Sánchez

“…The FEC reduction percentage at times A, B and C at T1 was 97%, 81.1% and 84.7% and a low-CI 95% of 67%; for T2 it was 51.5%, 46% and 17.4% and a low-CI 95% of -7.2%; and for T3 it was 97%, 91.2% and 89.6% and a low-CI 95% of 82.9%. …”
Get full text

Kinetic Analysis of the Reduction Processes of a Cisplatin Pt(IV) Prodrug by Mesna, Thioglycolic Acid, and Thiolactic Acid by Yanqing Xia, Hongwu Tian, Yanlei Li, Xinru Yang, Jinming Liu, Chunli Liu, Li Zhou, Lincai Zhang, Tiejian Li, Tiesheng Shi

“…The rate constants of the rate-determining steps were elucidated, revealing reactivity enhancements of (1.4–8.9) × 105 times when the thiols become thiolates. The species versus pH and reactivity of species versus pH distribution diagrams were constructed, demonstrating that the species ‒SCH2CH2SO3‒ of Mesna largely governs the total reactivity when pH > 5; in contrast, the form of Mesna per se (mainly as HSCH2CH2SO3‒) makes a negligible contribution. …”
Get full text

Effect of Al/Cu Ratio on Microstructure and High-Temperature Oxidation Resistance of Al_xCoCrCu_yFeNi High-Entropy Alloy Coatings by Ling Zhou, Hongxi Liu, Qinghua Zhang, Jiazhu Liang, Yuanrun Peng, Xuanhong Hao, Chen Yang, Yaxia Liu, Yueyi Wang

“…The microhardnesses of the Cu_1.0, Cu_0.7Al_0.3, Cu_0.5Al_0.5, Cu_0.3Al_0.7, and Al_1.0 HEA coatings were 2.01, 2.06, 2.08, 2.09, and 2.11 times that of the substrate, and compared with those of a Ti6Al4V alloy substrate, the oxidation rates of the HEA coatings decreased by 55%, 51%, 47%, 42%, and 35%, respectively. …”
Get full text

Pharmacological treatment in autism: a proposal for guidelines on common co-occurring psychiatric symptoms by Mariah A. Manter, Kirstin B. Birtwell, James Bath, Nora D. B. Friedman, Christopher J. Keary, Ann M. Neumeyer, Michelle L. Palumbo, Robyn P. Thom, Emily Stonestreet, Hannah Brooks, Kelly Dakin, Jacob M. Hooker, Christopher J. McDougle

“…Drawing on evidence-based clinical insights, these guidelines seek to support PCPs in making informed decisions when prescribing medications for ASD patients with co-occurring psychiatric and behavioral conditions, ultimately enhancing access to timely, comprehensive care for all individuals with ASD.…”
Get full text

Effect of Enriched Feed by n-3 fatty acids and 2% of n-6 fatty acid on Danio rerio Reproduction by N.B.P Utomo, L. Nurmalia, I. Mokoginta

“…There experimental diets containing 0.0; 1.0; 1.5 % n-3 fatty acid with 2.0 % n-6 fatty acid was fed to the fish, three times daily, at satiation, for two months. In order to evaluate the gonadal development of the broodstock, two gonads og fish was used for histologis preparation in every 7 days. …”
Get full text

Real-world outcomes in patients with melanoma brain metastasis: a US multisite retrospective chart review study of systemic treatments by Ning Ning, Sunandana Chandra, Andriy Moshyk, Divya Patel, Isabella C Glitza Oliva, Jennell Palaia, Leon A Sakkal, Natalia Han, Shardul Odak, Jordana K Schmier

“…Patients receiving nivolumab plus ipilimumab, compared with patients receiving anti-PD-1 monotherapy or BRAF/MEK inhibitors, had favourable baseline prognostic factors, such as younger age, fewer or smaller brain metastases, better Eastern Cooperative Oncology Group performance status and less frequently elevated lactate dehydrogenase. Median follow-up times were 15.4 months (range 0.1 to 37.0), 13.3 months (range 0.3 to 36.6) and 13.9 months (range 1.9 to 36.5), respectively. …”
Get full text

PEMBANGUNAN PERMUKIMAN KOLONIAL BELANDA DI JAWA : SEBUAH TINJAUAN TEORI by Dimas Wihardyanto, Ikaputra Ikaputra

“…Vereenigde Oostindische Compagnie (VOC) and the Dutch Colonial Government are the owners of the authority of the Kingdom of the Netherlands in occupying Indonesia which has different times, characters and perspectives. This article discusses the different characteristics of the construction of Dutch colonial settlements during the VOC and the Dutch Colonial Government through content analysis methods. …”
Get full text

Pregnancy rate following an estradiol-free fixed- TAI protocol during breeding and non-breeding season in water buffaloes under tropical condi- tions by Adriana Camacho de Gutiérrez, Obdulio Camacho, Steward Fernández, Yerixo González, Juan Carlos Gutiérrez-Añez

“… Fixed-timed artificial insemination (FTAI) protocols combining estradiol (E2) and progesterone (P4) are commonly used in the tropics, with adequate pregnancy rates throughout the year in buffaloes. …”
Get full text

Hubungan Konsumsi Junk Food dengan Status Gizi Lebih pada Siswa SD Pertiwi 2 Padang by Rizki Nur Amalia, Delmi Sulastri, Rima Semiarty

“…The average frequency of junk food consumption was 4,6±2,9 times per day and the average energy intake from junk food was 1046,5±918,4 kcal per day. …”
Get full text

Enhancing Diagnostic Accuracy of Lung Nodules in Chest Computed Tomography Using Artificial Intelligence: Retrospective Analysis by Weiqi Liu, You Wu, Zhuozhao Zheng, Mark Bittle, Wei Yu, Hadi Kharrazi

“…ConclusionsThe AI system enhanced lung nodule detection, offering the possibility of earlier disease identification and timely intervention. Nevertheless, the initial reduction in accuracy underscores the need for standardized diagnostic criteria and comprehensive training for radiologists to maximize the effectiveness of AI-enabled diagnostic systems.…”
Get full text

ViTAU: Facial paralysis recognition and analysis based on vision transformer and facial action units by Jia GAO, Wenhao CAI, Junli ZHAO, Fuqing DUAN

“…Facial nerve paralysis (FNP), commonly known as Bell’s palsy or facial paralysis, significantly affects patients’ daily lives and mental well-being. Timely identification and diagnosis are crucial for early treatment and rehabilitation. …”
Get full text

Prevalence and contributors to anaemia among children aged 6 to 59 months in Kyangwali Refugee settlement, Western Uganda: a cross-sectional study by Christine Nakimera, Philip Bright Bwajojo, William Kaweesa, Joan Nampiima, Faith Chebet, Sharifah Namuwawu, Martin Bwemage, Moses Nuwabasa, Regina Ndagire, Allan Lugaajju, Joel Tumwebaze, Catherine Nassozi Lwanira

“…Results The proportion of children with anaemia was 49.2% (95% CI: 44.4–53.9). Anaemia was 1.4 times (95% CI = 1.13–1.82; p = 0.003) more prevalent among wasted children than the normal children. …”
Get full text

Examining teen club attendance and viral load suppression among adolescents under differentiated HIV care in Malawi: a sub-optimal scenario by Rachel Chamanga, Tessa Musukwa, Louiser Kalitera, Felix Gent, Harrid Nkhoma, Kwashie Kudiabor, Alice Maida, Dumbani Kayira, Verita Buie, Godfrey Woelk, Thulani Maphosa

“…ALHIV on second-line treatments, were nearly four times more likely to have unsuppressed VL (aOR 3.7, 95% CI: 1.64–9.09) compared with those on first-line ART. …”
Get full text

Unmet Supportive Care Needs of Lung Cancer Survival Patients at Different Cancer Stages and Treatment Phases by Lee PY, Chen YA, Tsai TH, Chen CY, Shieh SH

“…Therefore, Healthcare professionals should provide appropriate and timely individualized care to address these needs.Keywords: unmet care needs, lung cancer, survivor, cancer stages and treatment…”
Get full text

Exploring the potential of underrated yet versatile crop Lunaria annua L.: New insights into honesty plant by Jovana Petrović, Daiana Almeida, Ângela Fernandes, Dejan Stojković, Dragana Robajac, Tayse F.F. da Silveira, Lillian Barros

“…The content of flavonoid compounds was several times higher than the content of phenolic acids (58.5 vs 9.4 mg/g). …”
Get full text

Coronil effectively inhibits the interaction of clinically relevant Omicron mutants of SARS-CoV-2 spike proteins with human ACE2 receptor by Acharya Balkrishna, Rishabh Dev, Sandeep Kumar, Anurag Varshney

“…Background: Accumulating evidence suggests that the receptor binding domain (RBD) of the SARS-CoV-2 Omicron variant has several times more binding affinity to the human angiotensin-converting enzyme 2 (ACE2) receptor compared to the RBD of the original Covid-19 strain. …”
Get full text

The T4/T3 quotient as a risk factor for differentiated thyroid cancer: a case control study by Mark Sasson, Emily Kay-Rivest, Rami Shoukrun, Anca Florea, Michael Hier, Veronique-Isabelle Forest, Michael Tamilia, Richard J. Payne

“…In this study a fT4/fT3 ratio >3.3 increased the risk of malignancy by 3.6 times (p-value =0.0013).…”
Get full text

The prevalence and associated disability burden of mental disorders in children and adolescents in China: a systematic analysis of data from the Global Burden of Disease StudyResea... by Wanyue Dong, Yunning Liu, Ruhai Bai, Lei Zhang, Maigeng Zhou

“…., bipolar disorder in Hebei was more than two times greater than that in other provinces). Although disparities in the distribution of mental disorder burden were observed across provinces, there was a reduction in income-related inequality, where the gap in the age-standardized DALY rates between the highest and lowest income provinces decreased by 61.7% between 1990 and 2021. …”
Get full text