Development of the therapeutic regimen based on the synergistic activity of cyclophosphamide and double-stranded DNA preparation which results in complete cure of mice engrafted wi... by E. A. Potter, E. V. Dolgova, A. S. Proskurina, Ya. R. Efremov, O. S. Taranov, V. P. Nikolin, N. A. Popova, T. D. Dubatolova, D. D. Petrova, E. I. Vereschagin, A. M. Minkevich, O. M. Andrushkevich, S. I. Baiborodin, V. A. Rogachev, A. A. Ostanin, E. R. Chernykh, N. A. Kolchanov, S. S. Bogachev

“…The first three CP/DNA injections appear to arrest Krebs-2 cells in late S-G2-M phase and result in their simultaneous progression into G1-S phase. The timing of the “final shot” is crucial for the successful treatment, which eradicates tumorigenic cell subpopulation from Krebs-2 ascites. …”
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Improving Clinical Management of Diabetic Macular Edema: Insights from a Global Survey of Patients, Healthcare Providers, and Clinic Staff by Focke Ziemssen, Michelle Sylvanowicz, Winfried M. Amoaku, Tariq Aslam, Bora Eldem, Robert P. Finger, Richard P. Gale, Laurent Kodjikian, Jean-François Korobelnik, Xiaofeng Lin, Anat Loewenstein, Paul Mitchell, Moira Murphy, David R. Owens, Nick Parker, Ian Pearce, Francisco J. Rodríguez, Jude Stern, S. James Talks, David T. Wong, Tien Yin Wong, Jane Barratt

“…Too many appointments, too short treatment intervals, difficulties in traveling to the clinic or arranging adequate support to travel, out-of-pocket costs, office/parking fees, and long waiting times were noted by all as contributing to increase the burden on the patient and caregiver. …”
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Germline BRCA testing in Denmark following invasive breast cancer: Progress since 2000 by Aleksandar M. Kostov, Maj-Britt Jensen, Bent Ejlertsen, Mads Thomassen, Caroline Maria Rossing, Inge S. Pedersen, Annabeth H. Petersen, Lise Lotte Christensen, Karin A.W. Wadt, Anne-Vibeke Lænkholm

“…Results: Test rates rose most significantly among patients aged under 40 years, increasing from 47% (2000–2005) to 88% (2012–2017), albeit with regional discrepancies. Test timing shifted in recent years, with most results within 6 months of BC diagnosis, primarily among the youngest patients. …”
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Preventive Effects of Intrauterine Injection of Bone Marrow-Derived Mesenchymal Stromal Cell-Conditioned Media on Uterine Fibrosis Immediately after Endometrial Curettage in Rabbit by Sanaz Bazoobandi, Nader Tanideh, Farhad Rahmanifar, Shahrokh Zare, Omid Koohi-Hosseinabadi, Iman Razeghian-Jahromi, Mehdi Dianatpour, Masoumeh Ahmadi, Arezoo Khoradmehr, Iraj Nabipour, Zahra Khodabandeh, Amin Tamadon

“…The MSC-CM were collected from cultivated BM-MSCs 48 hours after having been washed three times and replaced in serum-free media. Through a surgical approach, the caudal parts of the uteri were submitted to traumatic endometrial curettage, except for the intact negative uteri. …”
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Epidemiology of notifiable outbreaks in different hospital units in Saudi Arabia: A national descriptive study by Nawal M. Alanazi, Nasser H. Alshanbari, Hala M. Roushdy, Yahya I. Alnshbah, Eman Ali Barnawi, Nawaf M. Almatrafi, Rula Felemban, Zainah M. Al Shahrani, Nadeen Burhan, Aiman El-Saed, Khalid H. Alanazi

“…Methods: A retrospective analysis of national data collected through timely notifications to the MOH during 2023. Data included hospital and patient information. …”
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Multidisciplinary, multicenter consensus for the care of patients affected with Sturge–Weber syndrome by May El Hachem, Andrea Diociaiuti, Angela Galeotti, Francesca Grussu, Elena Gusson, Alessandro Ferretti, Carlo Efisio Marras, Davide Vecchio, Simona Cappelletti, Mariasavina Severino, Carlo Gandolfo, Simone Reali, Rosa Longo, Carmen D’Amore, Lodovica Gariazzo, Federica Marraffa, Marta Luisa Ciofi Degli Atti, Maria Margherita Mancardi, and the Sturge-Weber Syndrome Multidisciplinary Group

“…Results Through a Delphi consensus methodology, 28 recommendations have been developed concerning (i) dermatological SWS manifestations and related treatment timing and modalities, (ii) neurological referral, diagnosis, pharmacological treatment of neurological signs and symptoms, neurosurgical indications, neurocognitive evaluation and related treatment, psychosocial support and patient follow-up, (iii) diagnosis of ophthalmological manifestations, medical and surgical treatment, and follow-up, (iv) maxillofacial surgical treatment, (v) oral cavity assessment, care and follow-up, and (vi) primary care paediatrician/general practitioner involvement. …”
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Severe primary graft failure: Are there lasting impacts? Analysis from the PHTS Database by Jennifer Conway, MD, Tara Pidborochynski, MSc, James K. Kirklin, MD, Ryan Cantor, PhD, Hong Zhao, PhD, Aryaz Sheybani, MD, Jacqueline Lamour, MD, Lakshmi Gokanapudy Hahn, MD, Leslie Collins, MD, Jessica Laks, MD, Darren H. Freed, MD, PhD

“…Patients with PGF were younger, with higher proportion of congenital heart disease, longer cardiopulmonary bypass and ischemic times (IT), and more likely to be on extracorporeal membrane oxygenation or ventilator at HTx (all p < 0.0001, IT p = 0.0006). …”
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ATRIBUT PENATAAN RUANG-DALAM PADA CO-WORKING SPACE BERDASARKAN PILIHAN KONSUMEN by Ulfaizah Ulfa Sahril Nurfadhillah, Diananta Pramitasari

“…There were 201 respondents who live in Yogyakarta that were involved in the research who had several times used coffee & coworking  spaces for working, both for business and non-business in the past 6 months. …”
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Risk Prediction of Liver Injury in Pediatric Tuberculosis Treatment: Development of an Automated Machine Learning Model by Zeng Y, Lu H, Li S, Shi QZ, Liu L, Gong YQ, Yan P

“…The prediction model can assist clinicians to implement timely interventions and mitigation strategies, and formulate personalized medication regimens, thereby minimizing potential harm to high-risk children of ATB-DILI.Keywords: anti-tuberculosis drug-induced liver injury, children, retrospective study, automatic machine learning, gradient boost machine…”
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Postpartum Remote Health Coaching Intervention for Individuals With a Hypertensive Disorder of Pregnancy: Proof-of-Concept Study by Jaclyn D Borrowman, Lucas J Carr, Gary L Pierce, William T Story, Bethany Barone Gibbs, Kara M Whitaker

“…Hypertensive disorders of pregnancy (HDP) negatively impact acute and long-term cardiovascular health, with approximately 16% of all pregnancies affected. With CVD 2‐4 times more likely after HDP compared to normotensive pregnancies, effective interventions to promote cardiovascular health are imperative. …”
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Frailty Is Associated With Decreased Survival in Adult Patients With Nonoperative and Operative Traumatic Subdural Hemorrhage: A Retrospective Cohort Study of 381,754 Patients by Evan N. Courville, MD, Oluwafemi P. Owodunni, MD, MPH, Jordyn T. Courville, BS, Syed F. Kazim, MD, PhD, Alexander J. Kassicieh, BS, Allyson M. Hynes, MD, Meic H. Schmidt, MD, MBA, Christian A. Bowers, MD

“…Frailty was associated with major complications, LOS, mortality, and high level care discharges in a nationwide population of 381,754 patients. While timely surgery may be required for patients with tSDH, rapid deployment of point-of-care risk assessment for frailty creates an opportunity to equip physicians in allocating resources more precisely, possibly leading to better outcomes.…”
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Insight into influence of degradation metabolism of Firmicutes on the microstructure of anthracite coal by Yuewu Wang, Bingjun Liu, Sheng Xue, Yang Yang, Jian Chen, Jingbei Zhang, Chunshan Zheng, Tianyao Zhou

“…Fourier Transform Infrared Spectrometer (FTIR) experiments revealed that biodegradation stimulated by nitrogen source reduced the aromaticity of coal by 59.62% and enhanced the hydroxyl functional group content by 1.822 times. Mercury pressure and low-temperature nitrogen adsorption experiments showed that the micropore pore volume of the treated coal decreased by 34.09%, and the macropore pore volume accounted for an increased 168.28%, with an average pore size increment of 60.72 nm. …”
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Effects of moss restoration on surface runoff and initial soil erosion in a temperate vineyard by C. Gall, S. Oldenburg, M. Nebel, T. Scholten, S. Seitz

“…The effects of moss restoration on surface runoff and sediment discharge were examined compared to bare soil and cover crops using rainfall simulation experiments (45 mm h<span class="inline-formula">⁻¹</span> for 30 min) with small-scale runoff plots at three measurement times during 1 year (April, June, and October).</p> <p>Mosses initially showed considerable desiccation in summer, whereupon their growth declined. …”
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The effects of active play interventions on children’s fundamental movement skills: a systematic review by Xinmiao Zhang, Changhao Tang, Miao Geng, Kai Li, Cong Liu, Yujun Cai

“…The AP interventions in these 9 studies exhibited varying characteristics, with individual intervention durations ranging from 45 to 60 min, intervention frequencies ranging from once a week to four times per week, and intervention periods spanning from 4 weeks to 6 months. …”
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Polyploidization-driven transcriptomic dynamics in Medicago sativa neotetraploids: mRNA, smRNA and allele-specific gene expression by D. F. Santoro, G. Marconi, S. Capomaccio, M. Bocchini, A. W. Anderson, A. Finotti, M. Confalonieri, E. Albertini, D. Rosellini

“…Pathway analysis suggested that WGD could affect secondary metabolite biosynthesis, which in turn may influence forage quality. We found four times as many transcription factor genes among the polyploidization-affected genes than among those affected only by hybridization. …”
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An efficient decoupled 3-D axial anisotropic resistivity inversion for magnetotelluric data with OpenMP parallelization by Wisart Thongyoy, Weerachai Siripunvaraporn, Puwis Amatayakul, Tawat Rung-Arunwan, Kiyoshi Baba

“…The substantial parameter reduction is the key factor leading to significantly faster processing times and lower memory requirements. Both codes were validated with the synthetic model. …”
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Seroprevalence and Associated Risk Factors of Infectious Bovine Rhinotracheitis (IBR) and Animal Owners’ Knowledge, Attitude and Practice (KAP) Towards the Disease in Selected Dist... by Abdisa Mitiku Danu, Abriham Kebede Deresa, Chala Guyassa Dinagde

“…Local breed cattle were 2.055 times more likely to test positive for IBR with an odds ratio of 0.77 (95% CI 0.23–2.22) compared to crossbreed cattle. …”
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From pollution to sustainable environment: unlocking the role of energy intensity and renewable energy in highly pollutant nations by Zhi Zhen Zhou, Muhammad Shahid Hassan, Muhammad Ibrahim Saeed, Haider Mahmood, Rukhsana Kalim, Amira Houaneb

“…Environmental degradation is among one of the most critical issues of recent times. To address this critical challenge in highly pollutant nations, this research inquires about the role of Energy Intensity (EI) along with Renewable Energy Consumption (REC) and non-REC as controlling indicators in the carbon emissions’ model. …”
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The e-STROKE Study: The Design of a Prospective Observational Multicentral Study by Kateřina Dvorníková, Veronika Kunešová, Svatopluk Ostrý, Robert Mikulík, Michal Bar

“…Data collection includes demographic, clinical, and imaging data variables such as age, sex, ethnicity, risk factors, treatment times (OTT, DNT, and OGT), TICI scores, post-treatment hemorrhage (ECAS II), mRS outcome, stroke etiology, e-ASPECTS, acute ischemic volume (AIV), thrombus length on NCCT, CTA collateral score and collateral vessel density, location of large vessel occlusion, ischemic core, hypoperfusion volume, mismatch ratio and volume, final infarct volume, hemorrhage volume, and MRI in case of negative follow-up NCCT. …”
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Colostrum feeding practice and associated factors among mothers who come for postnatal care to Asella referral and teaching hospital, Arsi Zone, South-East Ethiopia by Gisha Haji, Gebi Agero, Amde Eshete, Abdurahman Hasan, Ahmed Hiko

“…Additionally, this study also identified factors associated with maternal colostrum feeding practice level such as urban residence, counseling on timely initiation of breastfeeding during antenatal care, and good maternal attitude toward colostrum feeding. …”
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