DIAGNOSTIC VALUE OF LABORATORY TESTS OF WOMEN IN THE DYNAMICS OF TREATMENT OF PERIODONTAL DISEASES CONCOMITANT WITH BACTERIAL VAGINOSIS by T.O. Petrushanko, A.D. Krutikova, E.I. Krutikova

“…Concentration of oral sIgA in both groups of women was restored after treatment, but the results of the III-A and III-B groups after treatment significantly differed (the result of sIgA in subjects of Group III-B was by 1.33 times higher than the value of Group III-A), indicating the higher efficacy of the proposed treatment regimen, which takes into account the presence of etiological agents of BV in the oral cavity. …”
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Creep characteristics of sandstone during freezing/thawing process by Yongjun SONG, Jinghui CAO, Keyan CHENG, Huimin YANG, Ran BI, Kun ZHANG

“…The steady-state creep rate after thawing increases by 3.65, 4.31, and 5.56 times compared to the steady-state creep rate at room temperature. …”
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Alleviating symptoms of paediatric acute rhinosinusitis and acute otitis media with otorrhea using nasal-spraying Bacillus probiotics: a randomized controlled trial by Thanh Huu Khieu, Dung Phuong Le, Binh Thanh Nguyen, Binh Thanh Ngo, Hong Thi Chu, Duc Minh Truong, Hung Minh Nguyen, Anh Hoa Nguyen, Tung Dinh Pham, Anh Thi Van Nguyen

“…Eighty-two patients (41 per group), aged 1 month to 12 years, received standard care along with nasal spraying of either physiological saline (Control group) or LiveSpo Navax (Navax group), administered three times daily over a 7-day follow-up period. A total of sixty-one patients (30–31 per group) completed the trial. …”
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Numerical Analysis of the Influence of Rectangular Deflectors and Geometry of L-Shaped Channel over the Performance of a Savonius Turbine by Andrei Luís Garcia Santos, Jaifer Corrêa Martins, Liércio André Isoldi, Gustavo da Cunha Dias, Luiz Alberto Oliveira Rocha, Jeferson Avila Souza, Elizaldo Domingues dos Santos

“…The use of deflectors resulted in increases of two and three times in available and mechanical powers, respectively, when the cases with one and two deflectors are compared with those without deflectors. …”
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Nonfimbrial Adhesin Mutants Reveal Divergent Escherichia coli O157:H7 Adherence Mechanisms on Human and Cattle Epithelial Cells by Matthew R. Moreau, Indira T. Kudva, Robab Katani, Rebecca Cote, Lingling Li, Terrance M. Arthur, Vivek Kapur

“…Supershedding (SS) is a phenomenon that has been reported in some cattle that shed more than 104 colony-forming units of O57:H7 per gram of feces, 100–1000 times more or greater than normal shedders. The unique bovine RAJ cell adherence model revealed that O157:H7 employs a LEE-independent mechanism of attachment to one of the RAJ cell types, the squamous epithelial (RSE) cells. …”
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Biological, cytomorphological and karyological heterogeneity of transformed cell lines derived from domestic pig (Sus scrofa L.) organs by B. L. Manin, E. A. Trofimova, V. L. Gavrilova, O. S. Puzankova

“…The cell hyperploidy is very likely to enhance telomerase activity, which in turn stabilizes immortalization and results in proliferative activity increase The cell viability has been maintained so far by regular reseedings (split ratio – 1:2–1:3) performed 1–2 times a week.…”
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Medical complexity in emergency and urgent care settings: a scoping review protocol by Diane Lorenzetti, Tanvir C Turin, Sumedh Bele, Eddy Lang, Doreen Rabi, Naomi Popeski, Marie-Claire Uwamahoro, Conne Lategan, Kate Yakubets, Cassandra Chisholm

“…When primary care is not able to provide timely care for chronic challenges or acute concerns, complex patients require care in emergency or urgent care settings. …”
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Collaborative design of a care pathway for pharmacy-based PrEP delivery in Nigeria: insights from stakeholder consultation by Obinna I. Ekwunife, Theodora C. Omenoba, Ugochi Eyong, Valentine Okelu, Michael Alagbile, Ifeanyi Ume, Ambrose Eze, Aderinola Fisayo, Gloria Aidoo-Frimpong, Farah Shroff, Chimezie Anyakora

“…Stakeholders expressed enthusiasm for pharmacy-based PrEP delivery while acknowledging challenges associated with clinic-based services, such as stigma, limited hours, and long wait times. The key recommendations included training pharmacy providers, increasing awareness, ensuring confidentiality, establishing referral linkages, and integrating program data into the Health Management Information System (HMIS) as well as ensuring commodity availability and access. …”
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Frequency and persistency of DNA vaccine encoding GP25 by oral on common carp by Sri Nuryati, , Yuliyanti, , Alimuddin

“…Feeding fish with diet supplemented with 1 mL E. coli DH5α containing DNA vaccine for each fish and two times a week allowed persistence of DNA vaccine in kindney and spleen.   …”
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Zinc absorption from maize-based meals enriched with edible house crickets: a randomized crossover stable-isotope study in Kenyan pre-school children by Nikolin Hilaj, Tele Boit, Pauline Andang’o, Christophe Zeder, Martin N. Mwangi, Marijke Hummel, Ornella Necochea Velazco, Joop J. A. van Loon, Marcel Dicke, Michael B. Zimmermann, Alida Melse-Boonstra

“…We found that AZ from meals with whole crickets (geometric mean: 0.36 mg; 95%CI: 0.30, 0.43) was 2.6 times higher than from low-enriched maize meals (0.14 mg; 0.11, 0.16; P < 0.001), while it was not different from low-chitin cricket flour meals. …”
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Induction of Somatic Embryogenesis and Organogenesis in Zimbabwean Sweet Potato (cv Brondal) by Rose T. Masekesa, Edmore Gasura, Gaudencia T. Kujeke, Elizabeth Ngadze, Farisai Chidzwondo

“…In contrast, plantlets produced under organogenesis were strong, grew vigorously, and could be subcultured several times. This disparity may be accounted for by the fact that the cv Brondal embryos that developed under SE were not exposed to an embryo maturation staged before plantlet germination was initiated. …”
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Cross-agency working when conducting a pragmatic RCT for older victims of crime: our experiences and lessons learned by Marc Serfaty, Jessica Satchell, Gloria K. Laycock, Chris R. Brewin, Marta Buszewicz, Gerard Leavey, Vari M. Drennan, Jonathan Cooke, Anthony Kessel

“…The delivery of therapy was impaired by waiting times, therapist availability and the quality of therapy. …”
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Malaria and Geohelminthiasis Coinfections in Expectant Women: Effect on Maternal Health and Birth Outcomes in a Malaria Endemic Region in Kenya by Wekesa Antony Wanyonyi, Chrispinus Siteti Mulambalah, David H. Mulama, Elizabeth Omukunda, Darwin Injete Siteti

“…Those coinfected with geohelminths and malaria parasites were four times likely to have anaemia (OR 4.137; 95% CI 2.088-8.195; P=0.001) compared with those infected with geohelminths or malaria parasites alone (OR 0.505; 95% CI 0.360-0.709; P=0.001 and OR 0.274; 95%CI 0.187-0.402 P=0.001, respectively). …”
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Inosine enhances the efficacy of immune‐checkpoint inhibitors in advanced solid tumors: A randomized, controlled, Phase 2 study by Haiqing Zhao, Wei Zhang, Yuting Lu, Yin Dong, Zhihao He, Hongchao Zhen, Qin Li

“…Methods This single‐center, prospective, randomized, open‐label study was conducted, from January 2021 to December 2022, in Beijing Friendship Hospital, Capital Medical University, and participants were randomly assigned (1:1) to either the inosine (trial) or non‐inosine (control) group that received inosine (dosage: 0.2 g, three times/day) + PD‐1/PD‐L1 inhibitor or only PD‐1/PD‐L1 inhibitor ± targeted ± chemotherapy, respectively. …”
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Characteristics of nursing homes and early preventive measures associated with risk of infection from COVID-19 in Lazio region, Italy: a retrospective case–control study by Leonardo Palombi, Alessio Abbondanzieri, Stefano Orlando, Tuba Mazhari, Gennaro Cerone, Fausto Ciccacci, Giuseppe Liotta, Sandro Mancinelli, Maria Cristina Marazzi

“…In binary logistic regression models, facilities with more than 15 beds were five times more likely to experience an outbreak than facilities with less than 15 beds OR=5.60 (CI 1.61 to 25.12; p value 0.002); admitting new residents to facilities was associated with a substantially higher risk of an outbreak: 6.46 (CI 1.58 to 27.58, p value 0.004). …”
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Abnormal Obesity Phenotype Is Associated with Reduced eGFR among Diabetes Mellitus and Hypertensive Patients in a Peri-Urban Community in Ghana by Richard K. D. Ephraim, Frederick Ahordzor, Kwame Kumi Asare, Evans Duah, Ibrahim W. Naveh-Fio, Grace Essuman, Justice Afrifa

“…After normalization with MHNO, the reduced eGFR was 1.51, 1.64, and 2.06 times expressed in MHO, MANO, and MAO. For the total samples, when MHNO was maintained as a reference, reduced eGFR was significantly associated with MANO (aOR = 3.07 (95% CI = 1.76–5.35), P<0.001) and MAO (aOR = 5.67 (95% CI = 2.66–17.27), P<0.001) even after adjusting for age, gender, smoking, and alcohol intake. …”
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iPSC-derived exosomes as amphotericin B carriers: a promising approach to combat cryptococcal meningitis by Jingyu Zhao, Jingyu Zhao, Wei Fang, Yangjie Gao, Jiquan Chen, Guizhen Wang, Julin Gu

“…Its MIC against Cryptococcus was over eight times lower than conventional AmB, significantly reducing fungal burden in the mouse brain and lowering serum inflammatory factors.ConclusionThe iPSC-Exo/AmB complex is a promising therapeutic strategy that enhances AmB efficacy while reducing toxicity, offering new hope for treating CM and other refractory fungal infections of the central nervous system.…”
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Laying hens prefer softer over harder mineral-based pecking stones and peck them more at the end of the light period by Madeleine McAuley, Linda J. Caston, Tina M. Widowski

“…Egg weights, shell breaking strength and thickness were determined 4 times in Phase 1. In Phase 1, disappearance increased from the first to second period (P = 0.001) and was even greater when the hens had been given Hard then Soft, compared to the opposite sequence (P = 0.0229). …”
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Comparative Sensitivity of MRI Indices for Myelin Assessment in Spinal Cord Regions by Philip Kyeremeh Jnr Oppong, Hiroyuki Hamaguchi, Maho Kitagawa, Nina Patzke, Kevin C. Wakeman, Khin Khin Tha

“…Quantitative indices known to be sensitive to myelin, including the myelin water fraction (MWF), magnetization transfer ratio (MTR), the signal ratio between T1- and T2-weighted images (T1W/T2W), fractional anisotropy (FA), mean diffusivity (MD), electrical conductivity (σ), and T1, T2, and T1ρ relaxation times were calculated. Their mean values were compared using repeated measures analysis of variance (ANOVA) and post hoc Bonferroni tests or Friedman and post hoc Wilcoxon tests to identify differences across GM and WM columns possessing distinct myelin distributions, as revealed by histological analysis. …”
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Blood Meal Utilization as Organic Fe Source for Polka Dot Grouper Cromileptes altivelis Growth Performance by Mia Setiawati, P. Purnama, I. Mokoginta

“…Feed was administrated 3 times a day at satiation. The use of organic Fe with 6% blood meal apparently resulted in a lower body Fe content, feed consumption and lipid retention but a higher protein retention and feed efficiency. …”
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