Microneedle technology for enhanced topical treatment of skin infections by Tingting Peng, Yangyan Chen, Xuanyu Luan, Wanshan Hu, Wentao Wu, Bing Guo, Chao Lu, Chuanbin Wu, Xin Pan

“…Also, integrating biosensing functionality to MNs offers point-of-care wearable medical devices for analyzing specific pathogens, disease status, and drug pharmacokinetics, thus providing personalized therapy for skin infections. Herein, we do a timely update on the development of MN technology in skin infection management, with a special focus on how to devise MNs for personalized antimicrobial therapy. …”
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<i>Agrobacterium rhizogenes</i>-Mediated Hairy Root Transformation in <i>Rosa</i> by Jun Lu, Yuwen Huang, Yuhan Guo, Chunguo Fan, Guozhen Yuan, Rui Zhou, Jingjing Sun, Mengjuan Bai, Kun Wang, Jinyi Liu, Changquan Wang

“…We explored the factors affecting the induction and transformation of hairy root cultures in rose by screening different types of explants, <i>Rosa</i> genotypes, <i>Agrobacterium</i> strains, media, and infection and co-cultivation times for genetic transformation under aseptic conditions. …”
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Assessment of <i>Alternaria</i> Toxins and Pesticides in Organic and Conventional Tomato Products: Insights into Contamination Patterns and Food Safety Implications by Tommaso Pacini, Teresa D’Amore, Stefano Sdogati, Emanuela Verdini, Rita Bibi, Angela Caporali, Elisa Cristofani, Carmen Maresca, Serenella Orsini, Alessandro Pelliccia, Eleonora Scoccia, Ivan Pecorelli

“…No correlation emerged between the detected levels of ATs and pesticides and the type of tomato cultivation, but the probability of pesticide contamination in conventional products was eight times higher than in organics. Some considerations about exposure assessment and risk characterization for ATs were also proposed in the overall population and in more sensitive and/or exposed subgroups, underlining the need for new focused toxicological and monitoring studies to establish reliable reference values. …”
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Hyponatremia due to preserved non-osmotic arginine vasopressin secretion in adipsic diabetes insipidus: a case report with review of literature by Yasufumi Seki, Shun Sugawara, Saya Suzuki, Yulia Minakuchi, Kazuhisa Kusuki, Yuzo Mizuno

“…A 53-year-old woman with hypopituitarism, receiving hydrocortisone and levothyroxine, experienced hyponatremia three times over 5 months without desmopressin treatment. …”
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Pregnancy and Postpartum Trends in Self‐Measured Blood Pressure and Derived Indices: The BOSHI Study by Seiya Izumi, Misato Nishimura, Noriyuki Iwama, Hasumi Tomita, Hirotaka Hamada, Taku Obara, Mami Ishikuro, Takahisa Murakami, Michihiro Satoh, Takuo Hirose, Masatoshi Saito, Takayoshi Ohkubo, Shinichi Kuriyama, Nobuo Yaegashi, Kazuhiko Hoshi, Yutaka Imai, Hirohito Metoki, the BOSHI Study Group

“…Among 237 participants with normotensive blood pressure (BP) during pregnancy and the postpartum period who were analyzed using mixed‐effects models for repeated measures, the SMBP was measured, on average, 14.3 times from the day before delivery to 28 days postpartum. …”
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Intraindividual variation in histone acetylation and its impact on autoimmune thyroid diseases by Emi Haga, Naoya Inoue, Yoshinori Iwatani, Yuya Arakawa, Emi Morita, Hidemi Hashimoto, Yusuke Noguchi, Yoh Hidaka, Mikio Watanabe

“…At 4 days, blood was also collected before meals three times a day (at 8:30–9:00, 12:30–13:00, and 16:30–17:00) to evaluate circadian variation. …”
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The water footprint of lithium extraction technologies: Insights from environmental impact reports in Argentina's salt flats by Walter Fernando Díaz Paz, Lucas Seghezzo, Ariela Griselda Salas Barboza, Melisa Escosteguy, Paula Valentina Arias-Alvarado, Eduardo Kruse, Marc Hufty, Martín Alejandro Iribarnegaray

“…Per unit of product, WF was 2.7 times higher in Fénix but BC was higher in Olaroz. …”
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Action Imagery and Observation in Neurorehabilitation for Parkinson’s Disease (ACTION-PD): Development of a User-Informed Home Training Intervention to Improve Functional Hand Move... by Judith Bek, Paul S. Holmes, Chesney E. Craig, Zoë C. Franklin, Matthew Sullivan, Jordan Webb, Trevor J. Crawford, Stefan Vogt, Emma Gowen, Ellen Poliakoff

“…Exploratory outcome measures included dexterity and timed action performance. Results. Usage and qualitative data provided preliminary evidence of acceptability and usability. …”
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Ageing response of Ni-rich NiTi shape memory alloy additively manufactured by electron beam freeform fabrication by R.P.M. Guimarães, B. Rauchdobler, F. Pixner, F.M.B. Ferraz, A. Mahdi, N. Enzinger, C. Poletti, S.T. Amancio-Filho

“…Ageing at 350 °C and 450 °C for 1, 6, and 12 h promoted phase transformations with R-phase formation, with Ms decreasing at shorter ageing times but increasing as precipitates coarsened. The solubilised sample aged at 350 °C for 12 h showed optimal superelastic behaviour, with nearly complete strain recovery and minimal permanent strain (1.3%) after ten compression cycles under 860 MPa. …”
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Race or Resource? BMI, Race, and Other Social Factors as Risk Factors for Interlimb Differences among Overweight Breast Cancer Survivors with Lymphedema by Lorraine T. Dean, Anagha Kumar, Taehoon Kim, Matthew Herling, Justin C. Brown, Zi Zhang, Margaret Evangelisti, Renata Hackley, Jiyoung Kim, Andrea Cheville, Andrea B. Troxel, J. Sanford Schwartz, Kathryn H. Schmitz

“…While observational analyses suggest up to 2.2 times increased risk of BCRL onset for Black breast cancer survivors, no studies have explored race or other social factors that may affect BCRL severity, operationalized by interlimb volume difference (ILD). …”
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The Efficacy of Single-Application NPWTi-d for the Salvage of Infected Breast Prostheses: A Multi-Center Study by Jason C. Llaneras, MD, Robert Craig Clark, MD, Lauren Antognoli, MD, Emily Finkelstein, MD, Luci Hulsman, BS, Luther Holton, MD, Devinder Singh, MD, R. Jason VonderHaar, MD, Risal Djohan, MD, Aladdin H. Hassanein, MD, Chris M. Reid, MD

“…NPWTi-d was applied for an average of 61 hours with dwell times of 18 minutes every 3 hours, using institution-specific instillates. …”
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Smart phone-based transcutaneous electrical acupoint stimulation as adjunctive therapy for hypertension (STAT-H trial): protocol for a cluster randomised controlled trial by Yu Wang, Xiao Wang, Ying Lin, Chao-Qun Yan, Guang-Xia Shi, Cun-Zhi Liu, Jing-Wen Yang, Jian-Feng Tu, Shi-Yan Yan, Xin-Tong Su, Li-Qiong Wang, Si-Bo Kang, Bao-Hong Mi, He-Wen Li, Xue-Zhou Wang

“…In addition to this, patients in the TEAS group will receive non-invasive acupoint electrical stimulation for 30 min at home, 4 times weekly for 12 weeks. The primary outcome will be the mean difference in the changes in office systolic blood pressure from baseline to 12 weeks between TEAS and usual care groups. …”
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Staging in the treatment of chronic calculous cholecystitis, complicated by choledocholithiasis by Alexander V. Smirnov, Vladimir R. Stankevich, Dmitry V. Sazonov, Artur R. Akhmedianov, Aishe A. Keshvedinova, Nikolay A. Solovyev, Yury V. Ivanov, Robert I. Khabazov

“…AIM: To define the optimal timings of performing the laparoscopic cholecystectomy after an endoscopic lithoextraction in cases of chronic calculous cholecystitis, complicated by choledocholithiasis. …”
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Enhanced Optical and Thermal Stability of Blue Pyrrole Derivatives for Color Filter in Image Sensors by Sunwoo Park, Sangwook Park, Saeyoung Oh, Hyukmin Kwon, Hayoon Lee, Kiho Lee, Chun Yoon, Jongwook Park

“…The molar extinction coefficient of HAPCP was 4.5 times higher than that of the commercially used Disperse Blue 359. …”
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Do sheep (Ovis aries) discriminate human emotional odors? by Izïa Larrigaldie, Fabrice Damon, Solène Mousqué, Bruno Patris, Léa Lansade, Benoist Schaal, Alexandra Destrez

“…The habituation stimulus was presented four times for one minute, followed by the dishabituation stimulus presented once for one minute. …”
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Carbon Dioxide Micro-Nano Bubbles Aeration Improves Carbon Fixation Efficiency for Succinic Acid Synthesis by <i>Escherichia coli</i> by Ying Chen, Hao Wu, Qianqian Huang, Jingwen Liao, Liuqing Wang, Yue Pan, Anming Xu, Wenming Zhang, Min Jiang

“…In pressurized fermentation with MNB aeration, the actual CO₂ utilization of <i>E. coli</i> Suc260-CsgA was 30.63% at 0.18 MPa, which was a 6.49-times improvement. The CO₂ requirement for SA synthesis decreased by 83.4%, and the fugitive emission of CO₂ was successfully controlled. …”
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Breastfeeding and Neonatal Age Influence Neutrophil-Driven Ontogeny of Blood Cell Populations in the First Week of Human Life by Sebastiano Montante, Rym Ben-Othman, Nelly Amenyogbe, Asimenia Angelidou, Anita van den Biggelaar, Bing Cai, Yixuan Chen, Alansana Darboe, Joann Diray-Arce, Rebecca Ford, Olubukola Idoko, Amy Lee, Mandy Lo, Kerry McEnaney, Mehrnoush Malek, David Martino, Geraldine Masiria, Oludare A. Odumade, William Pomat, Casey Shannon, Kinga Smolen, The EPIC Consortium, Al Ozonoff, Peter Richmond, Scott Tebbutt, Ofer Levy, Beate Kampmann, Ryan Brinkman, Tobias Kollmann

“…Our results suggest a common trajectory of immune development in newborns and possible association with timing of breastfeeding initiation, which may contribute to immune-mediated protection from infection in early life. …”
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Clinical Research Network: JHCRN Infrastructure and Lessons Learned by Rahul Kashyap, Gayane Yenokyan, Robert Joyner, Melissa Gerstenhaber, Mary Alderfer, Erika Siegrist, Joan Moore, Channing J. Paller, Hanan Aboumatar, James J. Potter, Stanley Watkins Jr, John E. Niederhuber, Daniel E. Ford, Adrian Dobs

“…ABSTRACT Clinical research studies are becoming increasingly complex resulting in compounded work burden and longer study cycle times, each fueling runaway costs. The impact of protocol complexity often results in inadequate recruitment and insufficient sample sizes, which challenges validity and generalizability. …”
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Relationship between Particulate Matter (PM10) and Airway Inflammation Measured with Exhaled Nitric Oxide Test in Seoul, Korea by Juwhan Choi, Jae Kyeom Sim, Jee Youn Oh, Young Seok Lee, Gyu Young Hur, Sung Yong Lee, Jae Jeong Shim, Ji-yong Moon, Kyung Hoon Min

“…To identify the most correlated times, we analyzed the correlation between the FeNO and PM10 daily average from the day of visit to 4 days before visit. …”
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Evidence of Rehabilitative Impact of Progressive Resistance Training (PRT) Programs in Parkinson Disease: An Umbrella Review by T. Paolucci, S. Sbardella, C. La Russa, F. Agostini, M. Mangone, L. Tramontana, A. Bernetti, M. Paoloni, L. Pezzi, R. G. Bellomo, V. Santilli, R. Saggini

“…Each study analyzed how PRT elicited positive effects on muscle strength in PD patients, suggesting 10 weeks on average of progressive resistance exercises for the upper and lower limbs two to three times per week. However, none of the studies considered the postworkout follow-up, and there was no detailed evidence about the value of PRT in preventing falls. …”
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