A synthetic biological secondary metabolite, Lycogenâ¢, produced and extracted from Rhodobacter sphaeroides WL-APD911 in an optimizatioal scale-up strategy by Cheng-Chin Wang, Shi-Ying Huang, Shu-Hung Huang, Zhi-Hong Wen, Jyun-Ying Huang, Wen-Sheng Liu, Hui-Min David Wang

“…At a 20 L fermentor, Lycogen⢠yields under the optimal culture condition are over 2 times than in the shake flask. The present results provide the Lycogen⢠optimal culture mediums, scale-up procedures and efficient extractions from R. sphaeroides WL-APD911. …”
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Facile construction of polyoxometalate-modified polyaryletherketone-based hybrid membranes with enhanced proton conductivity by Bo Hu, Qiuchen Du, Yang Yang, Dengdeng Li, Jiawang Fu, Bailing Liu, Hong-Ying Zang, Yangguang Li, Haiming Xie, Zhongmin Su

“…In particular, SPAEK-PW12-13% achieved an enhanced proton conductivity of 0.167 S∙cm−1 at 80 °C, which was 2.2 times greater than that of the pristine membrane. …”
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Convective Cold Pool Associated with Offshore Propagation of Convection System over the East Coast of Southern Sumatra, Indonesia by Erma Yulihastin, Ibnu Fathrio, Trismidianto, Fadli Nauval, Elfira Saufina, Wendi Harjupa, Didi Satiadi, Danang Eko Nuryanto

“…It is important to note that the intensity, duration, timing, and structure of heavy rainfall simulated were in good agreement with satellite-observed rainfall. …”
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A Quantum-Classical Collaborative Training Architecture Based on Quantum State Fidelity by Ryan L'Abbate, Anthony D'Onofrio, Samuel Stein, Samuel Yen-Chi Chen, Ang Li, Pin-Yu Chen, Juntao Chen, Ying Mao

“…In addition, it outperforms other quantum-based methods by up to 1.9 times and achieves similar accuracy while utilizing 70.59% fewer qubits.…”
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Elevated Incidence of Fractures in Solid-Organ Transplant Recipients on Glucocorticoid-Sparing Immunosuppressive Regimens by B. J. Edwards, A. Desai, J. Tsai, H. Du, G. R. Edwards, A. D. Bunta, A. Hahr, M. Abecassis, S. Sprague

“…The estimated relative risk of fracture was nearly seventeen-times higher in male liver transplant recipients ages 45–64 years compared with the general male population, and comparable to fracture rates on conventional immunosuppressant regimens. …”
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Efficacy of identifying Treatment-Resistant and non-Treatment-Resistant Schizophrenia using niacin skin flushing response combined with clinical feature by Jizhi Wang, Jinfeng Wang, Siyuan Wang, Yu Gu, Kai Liang, Yingxu Li, Zheng Zhang, Yan Li, Xiaoping Wang, Huijuan Guo, Jiansong Zhou

“…Abstract Treatment-resistant schizophrenia (TRS) is a serious mental disease and early identification of this disease is necessary for timely initiation of treatment strategies and management measures. …”
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β-Glucosidase VmGlu1 is required for toxin production and pathogenicity of Valsa mali by Xinyue Cui, Dewan Zhang, Liyong Gao, Na Liu, Sen Lian, Weichao Ren, Baohua Li, Caixia Wang

“…In this study, we found that the expression level of the β-glucosidase gene VmGlu1 was induced by 9.42-fold following rutin treatment, and VmGlu1 possessed the capability to degrade both rutin and phloridzin, but under the same conditions, VmGlu1 showed a distinct preference for rutin degradation, with an initial degradation rate 8.66 times higher than that of VmGlu2. Targeted deletion of VmGlu1 resulted in a 99.32% reduction in pycnidia production, a nearly 33% decrease in toxin production, and a significant decrease in pathogenicity on apple twigs and leaves. …”
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Incorporation of κ-carrageenan improves the practical features of agar/konjac glucomannan/κ-carrageenan ternary system by Dongling Qiao, Hao Li, Fatang Jiang, Siming Zhao, Sheng Chen, Binjia Zhang

“…For instance, the ternary composites could show hardness about 3 to 4 times higher than that for binary counterpart. These gels were dehydrated to acquire ternary composites. …”
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Effects of aquatic exercise compared with land-based exercise on the body composition and function of older adults with sarcopenia: protocol for a randomised controlled trial by Na Li, Fang Cheng, Jinfeng Yang, Yuanpeng Liao, PeiJie Sun, Weicheng Yang, Jinqi Yang, Jianxin Ran

“…Assessments will be conducted four times: initially (before intervention), after 8 weeks (intermediate), after 16 weeks (final) and 16 weeks after the end of intervention (follow-up). …”
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Modeling dynamic changes in type 1 diabetes progression:Quantifying $\beta$-cell variation after the appearance ofislet-specific autoimmune responses by Patrick Nelson, Noah Smith, Stanca Ciupe, Weiping Zou, Gilbert S. Omenn, Massimo Pietropaolo

“…The results provide information about the concentrations and ratios of pathogenic T cells and regulatory T cells, the timing in which $\beta$-cells become dysfunctional, and how certain kinetic parameters affect the progression to T1DM. …”
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A comprehensive review of massive transfusion and major hemorrhage protocols: origins, core principles and practical implementation by David Silveira Marinho, Denise Menezes Brunetta, Luciana Maria de Barros Carlos, Luany Elvira Mesquita Carvalho, Jessica Silva Miranda

“…The latter involves the use of antifibrinolytics, correction of preconditions of hemostasis (calcium, pH and temperature) and the early and rapid restoration of intravascular volume with blood products. To enable timely availability and transfusion of blood products, specific actions in different hospital areas need to be synchronized, which are usually organized through Massive Transfusion Protocols or, as they have recently been rebranded, Major Hemorrhage Protocols (MHPs). …”
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Therapeutic Adherence of Patients with Type 2 Diabetes Mellitus in Four Health Areas of the Country by Addys María Díaz Piñera, Armando Rodríguez Salvá, Fernando Jesús Achiong Estupiñán, Dania Lidia Cardona Garbey, Geominia Maldonado Cantillo, Esteban Augusto Londoño Agudelo, Patrick Van der Stuyft

“…<br /><strong>Conclusions:</strong> the non-availability of medications in the pharmacy, forgetting to take them and at the established times were the main barriers reported by patients, this must be taken into account to have a favorable impact on the control of diabetes mellitus.…”
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Kinetic origin of hysteresis and the strongly enhanced reversible barocaloric effect by regulating the atomic coordination environment by Zi-Bing Yu, Hou-Bo Zhou, Feng-Xia Hu, Jian-Tao Wang, Fei-Ran Shen, Lun-Hua He, Zheng-Ying Tian, Yi-Hong Gao, Bing-Jie Wang, Yuan Lin, Yue Kan, Jing Wang, Yun-Zhong Chen, Ji-Rong Sun, Tong-Yun Zhao, Bao-Gen Shen

“…The maximum ΔSrev of MnCo(Ge0.98In0.02) is 1.7 times greater than that of Mn(Co0.98In0.02)Ge. These results reveal the atomic-scale mechanism regulating hysteresis and provide insights into tailoring the functional properties of novel caloric refrigeration materials.…”
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Control strategy for the core power in an accelerator drive sub-critical system by Xinxin Li, Yuan He, Wenjing Ma, Wenjuan Cui, Zhiyong He, Detai Zhou, Hai Zheng, Feng Yang, Yuhui Guo, Haihua Niu, Kai Yin, Shiwu Dang

“…Both the pulse length and the repetition rate are assigned by a timing system. Secondly, the power is adjusted precisely by changing the beam intensity. …”
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A Liquid Chromatography with Tandem Mass Spectrometry-Based Proteomic Analysis of Primary Cultured Cells and Subcultured Cells Using Mouse Adipose-Derived Mesenchymal Stem Cells by Yoshiki Nakashima, Saifun Nahar, Chika Miyagi-Shiohira, Takao Kinjo, Naoya Kobayashi, Issei Saitoh, Masami Watanabe, Jiro Fujita, Hirofumi Noguchi

“…In this study, a protein expression analysis was performed by liquid chromatography with tandem mass spectrometry (LC-MS/MS) using mouse primary cultured cells (P0) and cells passaged three times (P3) as samples. A total of 256 proteins were classified as cellular process-related proteins, while 179 were classified as metabolic process-related proteins in P0. …”
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<i>Musa paradisiaca</i> L. Inflorescence Abrogates Neutrophil Activation by Downregulating TLR4/NF-KB Signaling Pathway in LPS-Induced Acute Lung Injury Model by Francisco Allysson Assis Ferreira Gadelha, Raquel Fragoso Pereira Cavalcanti, Cosmo Isaias Duvirgens Vieira, Joao Batista De Oliveira, Louíse Mangueira De Lima, Adriano Francisco Alves, Matheus Marley Bezerra Pessoa, Leônia Maria Batista, Naiara Naiana Dejani, Marcia Regina Piuvezam

“…<b>Methods</b>: Swiss mice were challenged with lipopolysaccharide and treated with HEM after 1, 24, and 48 h (five animals/group, three times). <b>Results</b>: The HEM-treated ALI mice presented a decrease in neutrophil migration in the bronchoalveolar lavage fluid (BALF), in the alveolar region, and in the blood, correlating to downregulation of CD18 expression. …”
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Modulating Brain Connectivity by Simultaneous Dual-Mode Stimulation over Bilateral Primary Motor Cortices in Subacute Stroke Patients by Jungsoo Lee, Eunhee Park, Ahee Lee, Won Hyuk Chang, Dae-Shik Kim, Yong-Il Shin, Yun-Hee Kim

“…We assessed each patient’s motor function using the Fugl-Meyer assessment score and acquired their resting-state fMRI data at two times: prior to stimulation and 2 months after stimulation. …”
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Income-related inequalities in the prevalence of dental pain intensity in adults: gender differences by Carolina Veloso Lima, Alanna Barros de Arruda, Mayara dos Santos Noronha, Aline Araujo Sampaio, Marise Fagundes Silveira, Andrea Maria Eleuterio de Barros Lima Martins, Raquel Conceição Ferreira, Aline Netto de Godoy, Daniela Marques da Silva Sousa, Patrick Pereira Garcia, Cyrene Piazera Silva Costa, João Gabriel Silva Souza, Bárbara Emanoele Costa Oliveira

“…Those living in municipalities with higher Gini Index values reported 1.26 times (95% CI: 1.01–1.56) greater dental pain intensity compared to adults living in cities with lower Gini Index values, even after adjustment by variables. …”
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Quantifying preferential flow occurrence in dependence of land cover on the southern slopes of Mount Kilimanjaro, Tanzania by Frank Paul Shagega, Fabia Codalli, Suzanne Jacobs, Subira Eva Munishi, David Windhorst, Lutz Breuer

“…After a separation and clustering of rainfall events we assessed the dynamics of soil moisture responses. The sequence and timing of soil moisture changes informed about the occurrence of preferential versus sequential (matrix) flow. …”
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The Usage of Lion’s Mane in Sports and Its Metabolic Impact – a literature review by Karolina Stankevič, Kamila Fuczyło, Ewelina Kopczyńska, Piotr Kulej, Wiktor Biesiada, Justyna Weronika Kmieć, Justyna Woźniak, Anna-Mariia Chernysh, Aleksandra Dusińska, Jakub Waszczyński

“…However, direct evidence on its impact on athletic metrics such as endurance, strength, or recovery times is limited. Preclinical studies are promising but need to be validated in well-designed human trials. …”
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