Endothelial protease-activated receptor 4: impotent or important? by Rahul Rajala, Rahul Rajala, Rahul Rajala, Courtney T. Griffin, Courtney T. Griffin

“…Since we have finally shown PAR4 to be present and functional on ECs in vivo, it is important to outline why such controversy arose over the last two decades and, more importantly, why the receptor was undervalued on ECs. This timely review aims to inspire investigators in the field of vascular biology to study the regulatory aspect of endothelial PAR4 and its relationship with the more highly expressed PAR1.…”
Get full text

Investigating the effect of neighboring buildings’ orientation and the passage on the amount of energy consumption (case example: common residential buildings in Tehran) by Meysam Zekavat, Mansoure Tahbaz, Mohammad Reza Hafezi

“…This is approximately three times the ideal building's energy consumption. The northern blocks consume about 5% more energy than the southern blocks. …”
Get full text

Distinctive blood and salivary proteomics signatures in Qatari individuals at high risk for cardiovascular disease by Ghada Yousif, Selvasankar Murugesan, Mohamed Nadhir Djekidel, Annalisa Terranegra, Giusy Gentilcore, Jean Charles Grivel, Souhaila Al Khodor

“…Abstract Cardiovascular disease (CVD) remains a leading cause of global morbidity and mortality. Timely diagnosis is important in reducing both short and long-term health complications. …”
Get full text

Chemicals That Disrupt the Endocrine System and Their Effects on Behavior by Yousaf Khan1, Abdul Sattar1, Syed Amin Ullah1, Zia-Ur-Rehman2, Hakimullah3, Madeeha Bibi4, Hina Sarfraz1, Anila Mukhtiar1

“…Still a lot is to be done and there is a huge potential of research in this area which if focused properly can prove as an agent of change in the field of Medical and Health Sciences and Human race can be saved from diverse diseases which may be linked to these disruptors and can be treated timely. In the light of the above, there is dire need of research in this area so as to be familiar to the hazardous and health related issues in Humans caused by these disruptors and to find an alternative for the chemicals and items in order to save the humanity from the negative impacts of these disruptors. …”
Get full text

Efficacy and Safety of Bicyclol Treatment for Non-Alcoholic Fatty Liver Disease: Results of a Cohort Study by I. Yu. Pirogova, S. V. Yakovleva, T. V. Neuymina, S. P. Sinitsyn, V. S. Chulkov, T. N. Shamaeva

“…The number of patients with indolent steatosis (less than 2nd stage) increased 2 times (p < 0.001). No significant changes were found in the group without drug therapy.Conclusions.  …”
Get full text

Immunological efficiency of Haemophilus influenzae type b polyribosyl ribitol phosphate combined with detoxified lipooligosaccharide in a rabbit model by Amin Arsang, Seyed Davar Siadat, Masoumeh Saberpour, Farshad Nojoomi

“…Rabbit groups were immunized with PRP (10 µg), dLOS (20 µg), and PRP-dLOS combine (10 µg+20 µg) three times on days 0, 14, and 28. Serum samples were acquired on days 0, 14, and 28 post-immunization, then IgM and IgG levels were assayed by enzyme-linked immunosorbent assay. …”
Get full text

A Case of Atypical Neurofibromatous Neoplasm of Uncertain Biologic Potential: Unravelling the Enigma by Apoorva Pande, Samarth Shukla, Sourya Acharya, Pravin Gadkari, Milind Pande

“…This case underscores the complexity and diagnostic challenges associated with such swellings, necessitating thorough examination and ongoing monitoring for timely intervention. This case highlights the importance of thorough clinical evaluation, histopathological examination, and molecular analysis in accurately characterising such tumours, guiding clinical management decisions, and ensuring optimal patient outcomes. …”
Get full text

Research priorities for preterm lung health research across the lifespan: a community priority setting partnership by Anne McKenzie, Shannon J Simpson, Naomi R Hemy, Amber Bates, Belinda Frank

“…The substantial gaps in our understanding of prematurity-associated lung disease presented a timely opportunity to determine the community’s research priorities.Objective To conduct a priority setting partnership (PSP) to determine the top 10 research priorities for preterm lung health.Design We undertook a modified James Lind Alliance methodology comprising three main stages: (1) an idea generating survey with open questions to ascertain the community’s most important ideas for future preterm lung health research, (2) prioritisation survey to distill the main themes into a shortlist of 20 and (3) consensus workshop where participants were tasked with ranking their final top 10. …”
Get full text

Self-Reported Violence Experienced by Swiss Prehospital Emergency Care Providers by Simon Savoy, Pierre-Nicolas Carron, Nathalie Romain-Glassey, Nicolas Beysard

“…Most declared to be the victim of such violence between one and three times during the year. In all cases of violence described, the patient and/or a relative initiated aggressive behavior in 96% of cases. …”
Get full text

Predicting Future Surface Runoff Delivered to the Euphrates River Using LARSWG and SWAT Models: (Sahiliya Valley in the Iraqi Western    Desert as a Case Study) by Wisam Abdulabbas Abidalla, Basim Sh. Abed

“…The data results from SWAT modelling shows that maximum runoff occurs in October and November in winter season, and March in spring season in each year, and the runoff occurs at a rate of one to four (1-4) times annually, and in some years twice only. This means that the amount of surface runoff water added to the Euphrates River is limited from this valley. …”
Get full text

Study on the Atomization and Dust-Reduction Performance of a New Type of External Pneumatic Vortex Fog Curtain Dust Removal Device in Fully Mechanized Excavation Face by Deji Jing, Rina An, Jingxu Chen, Shaocheng Ge, Liying Sun

“…Firstly, dust migration laws at different times are simulated and analyzed by COMSOL software, and the functional relationship of dust concentration distribution above 50 mg/m3 at different heights and different wind speed is derived. …”
Get full text

Flexible and cost-effective deep learning for accelerated multi-parametric relaxometry using phase-cycled bSSFP by Florian Birk, Lucas Mahler, Julius Steiglechner, Qi Wang, Klaus Scheffler, Rahel Heule

“…This work emphasizes the advantages of in silico DNN MP-qMRI pipelines for rapid data generation and DNN training without extensive dictionary generation, long parameter inference times, or prolonged data acquisition, highlighting the flexible and rapid nature of lightweight machine learning applications for MP-qMRI.…”
Get full text

The Coincidence of Newly Diagnosed Type 1 Diabetes Mellitus with IgM Antibody Positivity to Enteroviruses and Respiratory Tract Viruses by Murat Karaoglan, Fahriye Eksi

“…The IgM antibodies against enteroviruses and respiratory viruses were studied using the indirect immunofluorescence assay (IFA) test, and no CBV4-specific RNA was detected in the children. The onset times of T1DM were classified into fall-winter and spring-summer seasons and separated into cold, moderate, or warm months in terms of temperature. …”
Get full text

Features of Medical Care Providing to Patients with Digestive Diseases in the Krasnodar Region during the COVID-19 Pandemic by N. V. Korochanskaya, V. M. Durleshter, S. A. Gabriel, O. V. Kovalevskaya, S. N. Serikova, M. A. Basenko

“…Healthcare system workload in the Krasnodar Region increased significantly during the coronavirus pandemic that required a number of structural adjustments. In recent times, the regional health care is returning to the planned mode of providing medical care.…”
Get full text

Nebulised 3% hypertonic saline versus 0.9% saline for treating patients hospitalised with acute bronchiolitis: protocol for a randomised, double-blind, multicentre trial by Sara Szupieńko, Aleksandra Buczek, Henryk Szymański

“…A total of 140 children will be randomised (1:1) to receive either hypertonic saline nebulisation (5 mL, three times a day) or normal saline at the same dose. The primary outcome measure will be the duration of hospitalisation.Ethics and dissemination The Bioethics Committee of the Lower Silesia Medical Chamber in Wroclaw approved the study protocol (4/PNDR/2023). …”
Get full text

In Vitro Cercaricidal Activity, Acute Toxicity, and GC/MS Analysis of Some Selected Ghanaian Medicinal Plants by Bright Osei-Mensah, Yaw Duah Boakye, William Kofi Anyan, Theresa Appiah Agana, Eugene Agyei Aboagye, Ivy Bentil, Elvis Suatey Lomotey, Francis Adu, Christian Agyare

“…All four plants showed relatively different levels of activity against S. mansoni cercariae at different times and concentrations. The LC50 values of the plant extracts were determined at the end of the assay. …”
Get full text

Cognitive enhancing effect of an extract of Swertia chirata against memory impairment induced by aluminum chloride by Reena Deshmukh, Manisha Jaiswal, Anshita Shukla, Umesh Patil, Mukesh Sharma

“…Results: Swertia chirata ethanolic extract exhibited longer exploration times for unfamiliar objects compared to familiar ones. …”
Get full text

Health information ties: preliminary findings on the health information seeking behaviour of an African-American community by Ophelia T. Morey

“…Random samples were drawn three times until at least 200 telephone surveys were completed. …”
Get full text

Access to information about the activities of the Security Service of Ukraine in the context of countering disinformation by A. I. Marushchak, N. O. Kudriavtseva

“…On the example of the Security Service of Ukraine, the peculiarities of citizens' access to information about its activities are considered, the possibility of using mechanisms of access to public information in the context of countering disinformation about the state body is investigated. Thus, the role of timely and high-quality filling of official web resources of authorities, in particular the Security Service of Ukraine, was considered. …”
Get full text

Betatrophin Acts as a Diagnostic Biomarker in Type 2 Diabetes Mellitus and Is Negatively Associated with HDL-Cholesterol by Min Yi, Rong-ping Chen, Rui Yang, Xian-feng Guo, Jia-chun Zhang, Hong Chen

“…Circulating betatrophin levels were approximately 1.8 times higher in T2DM patients than in NDM individuals (median 747.12 versus 407.41 pg/mL, P<0.001). …”
Get full text