Development and Evaluation of Polymethacrylate-Based Ophthalmic Nanofiber Inserts Containing Dual Drug-Loaded Dorzolamide and Timolol: In Vivo Study in Rabbit’s Eye by Ahmad Karami, Shahla Mirzaeei, Leila Rezaei, Ali Nokhodchi

“…The Area Under the Curve (AUC0-72) for DOR and TIM in EDT formulations was approximately 3216.63 ± 63.25 µg·h/mL and 2598.89 ± 46.65 µg·h/mL, respectively, with Mean Residence Times (MRTs) of approximately 21.6 ± 0.19 h and 16.29 ± 6.44 h. …”
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Menopausal Hormone Therapy: Its Role in the Prevention of Cardiovascular Diseases and the Risk of Breast Cancer in Women by Tam Thai Thanh Tran, Thu Minh Phung, Anh Thi Mai Do, Quynh Tran Mai Ly, Tin Hoang Nguyen

“…Findings in Brief: While MHT may have favorable effects when started early, introducing it later in the course of atherosclerosis may pose major dangers, underlining the importance of timing in hormone therapy. Estrogen-only therapy has a greater favorable effect on CVDs than the estrogen-progesterone combination. …”
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Global Education Development Plan to Build Sustainable Education Based on Artificial Intelligence by Siti Marisa, Gunawan Gunawan, Evi Susilawati

“…This technology can provide more objective and comprehensive assessment of student progress, helping teachers to provide more timely feedback and support better decision-making in learning planning. …”
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Risk factors related to COVID-19. Turcios Lima Polyclinic. Pinar del Rio, 2020-2021 by Jorge Félix Rodríguez Ramos, Gema Chávez Ivizate, Raquel Piloto González

“…<p><strong>Background</strong>: timely recognition of certain risk factors helps to identify COVID-19 infection at an early stage, which, together with interdisciplinary and intersectoral participation, allows for the implementation of better strategies and reduction of morbidity and mortality.…”
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Insights into the toxic impact of long-term exposure to diethyl phthalate on commercially important species Catla (Labeo catla) by Satabdi Ganguly, Basanta Kumar Das, Anupam Adhikari, Subir Kumar Nag

“…The brain FSH levels increased by 11.24 and 55.42% times than control in both the doses. This led to an increase in circulating sex steroids E2 (41.62%) and 11 KT (24.59%) and eventually triggered hepatic Vtg production (23.90%) in a dose-dependent manner. …”
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Protein hydrolysates of niosome-encapsulated skipjack (Katsuwonus pelamis) viscera: Antioxidant, anticancer, and release properties by Shima Kaveh, Alireza Sadeghi Mahoonak, Vahid Erfani-Moghadam, Mohammad Ghorbani, Aliakbar Gholamhosseinpour, Mojtaba Raeisi

“…So, this study aimed to produce skipjack viscera protein hydrolysates (FPH) using different enzymes (pancreatin, alcalase, trypsin, and pepsin) at different hydrolysis times. Additionally, the study investigated the stabilization of FPH by partially replacing cholesterol with cholecalciferol and squalane in nano-sized niosomes. …”
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Simulation-based validation of a method to detect changes in SARS-CoV-2 reinfection risk. by Belinda Lombard, Harry Moultrie, Juliet R C Pulliam, Cari van Schalkwyk

“…The model's performance was assessed on simulated data representative of the South African SARS-CoV-2 epidemic, reflecting its timing of waves and outbreak magnitude. Model performance under similar scenarios may be different in settings with smaller epidemics (and therefore smaller numbers of reinfections). …”
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The unique association between estimated pulse wave velocity and the prevalence of diabetic kidney disease: a cross-sectional study by Shuwu Wei, Xinyu Pan, Yao Xiao, Junping Wei

“…Integrating ePWV into routine clinical evaluations enable timely interventions and personalized management approaches.…”
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Introduction of an Auxiliary Breaker into the Generator-Transformer Block for Energy Saving in Open Switchgear Circuits of Power Plants by A. S. Barukin, M. Ya. Kletsel, A. Zh. Dinmukhanbetova, D. A. Amirbek

“…It is demonstrated that the presence of a generator breaker in the blocks makes it possible to reduce these energy-saving efficiency indicators several times. A technique for determining the failure rate of a hypothetical circuit breaker, which, in the case of traditional replacement, is capable of producing the same effect as an SF6 circuit breaker inserted is proposed. …”
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Home care program for high-risk pregnancies: a qualitative study of care providers perspectives from Iran by Masoumeh sayahi, Shahrbanoo Salehin, Mehrnoosh Zakerkish, Afsaneh Keramat, Shahrbanoo Goli

“…Abstract Background High-risk pregnancies are accompanied by significant complications for the mother, fetus, and baby if not controlled and received timely care. During home antenatal care, high-risk pregnant women can receive non-medical interventions by a home visitor. …”
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Temperature and Temperature Stress Analysis in Mass Concrete under Cold Environments of Strong Wind and Large Diurnal Temperature Range by Guoqing Wang, Meng He, Canjun Zhou, Wen Xie, Xinglin Liu, Jin Chen, Hua Liu, Bingbing Lei, Mingli Zhang

“…Therefore, the temperature stresses of the horizontal surface under wind speed levels 3, 4, 5, and 1.25 times large diurnal temperature range easily exceed the tensile strength; then, the temperature crack will appear. …”
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INCREASING VALUE-BASED COMPANY POTENTIAL: THE GROUNDS OF A FULL-SCALE ASSESSMENT by Romans Dyakons, Vsevolods Karajevs, Rostislavs Kopitovs

“…The objective of methodological foundations is to facilitate the timely identification of potential vulnerabilities that could lead to future losses in sustainability. …”
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Numerical Investigations on the Effect of Fracture Length Distribution on the Representative Elementary Volume of 3D Discrete Fracture Networks by Ding Liu, Hai Pu, Shiru Guo, Ziheng Sha, Chong Li

“…When a=4.5, the VREV rapidly increases to more than 3.4 times than that when a=4.0. The fluid flow becomes more inhomogeneous due to the small nonpersistent fractures that dominate the preferential flow paths when a exceeds a certain value (i.e., 4.5). …”
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Effect of Porous Coating on Heat Transfer in Minichannels with Intensive Localised Heating by Pukhovoy M.V., Zaitsev D.V.

“…The values of heat transfer coefficients and critical heat flux on porous surfaces are significantly (up to 3 times) higher than for a smooth surface. The values of critical heat flux reached 1.2 kW/cm2, and the values of heat transfer coefficient reached 100 kW/(m2 K). …”
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Reducing Undernutrition through Counseling on Diversified Food Intake among Adult People Living with HIV on HAART, Northern Ethiopia by Weldegebrial Hayelom Tedla, Alemseged Aregay, Kidanu Gebremariam, Mulugeta Woldu Abrha, Haftom Gebrehiwot Weldearegay

“…Age of patients, average monthly income, nutritional counseling during visits, and diet diversity were the independent factors of undernutrition. Counseling on well-timed and sufficient consumption of nutritious foods, economic strengthening, and livelihood activities is important. …”
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Effect of electroacupuncture on symptoms of female pelvic organ prolapse (stage II–III) (EAPOP study): protocol of a randomised controlled trial by Yan Yan, Zhishun Liu, Huan Chen, Xiaoxu Liu, Hangyu Shi

“…One hundred and sixty eligible women will be assigned with a 1:1 ratio to have received either EA or SEA for 24 times in 12 weeks and followed-up for 24 weeks. The primary outcome will be the change on the total score of the Pelvic Floor Distress Inventory-short form 20 at week 12 from baseline, and will be analysed by t-test or multiple regression model. …”
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Congenital vitamin D deficiency: presenting with feeding difficulty in early infancy: a case report by Mesfin Wubishet, Tesfa G. Meskel, Kibret Enyew

“…Therefore, clinicians should remain vigilant and maintain a high index of suspicion to ensure timely diagnosis and treatment. It is essential to measure serum calcium and vitamin D levels in both the mother and infant, particularly for newborns of high-risk mothers, such as those who wear conservative religious clothing like a niqab. …”
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Kitchen Workstation and Stress in Meal Preparation by Women in Households of Ogun State, Nigeria by Gbolahan Ayodapo Otufale, Modinat Iyadunni Lasisi

“…The results revealed that 42.9%, 47.6%, 57.1% of the women used modern kitchen workstation partially equipped with furniture and appliance with meal prepared two times daily and spent 3-5hours in preparing meal for members of the household. …”
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Evaluation of incubated defatted rubber seed meal with sheep rumen liquor for Pangasius diet by Muhammad Agus Suprayudi, Winda Styani Irawan, Nur Bambang Priyo Utomo

“…Feeding was done three times a day to satiation. No significant different was found on fish-protein retention and survival rate in all treatments. …”
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Speckled-egg staining appearance of cryptococcal osteomyelitis in an immunocompetent patient by Matthew Alexander Stack, John-Paul Lavik, Jack G. Schneider, Brynne E. Cross

“…However, cryptococcal infections are being increasingly reported in atypical hosts, at times with non-characteristic histochemical staining appearances. …”
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