Case report: a rare case of diffusely metastatic BRAF V600E-mutated colorectal cancer with concomitant infiltration of the skin and parotid gland by Aristeidis E. Boukouris, Ioannis Kokkinakis, Elias Drakos, Maria Sfakianaki, Maria Tzardi, Dimitrios Mavroudis, Dimitrios Mavroudis, John Souglakos, John Souglakos

“…BRAF V600E-mutated CRC can follow an aggressive and often unpredictable clinical course in the metastatic setting that physicians should be aware of, and the molecular profile of the tumor at diagnosis could be useful for comprehensive and timely management.…”
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Near-Infrared Spectroscopy during the Verbal Fluency Task before and after Treatment with Image Exposure and SSRI Therapy in Patients with Obsessive-Compulsive Disorder by Mari Nakanishi, Harumi Oshita, Yoshihiro Tanaka, Ayako Inoue, Chiwa Kawashima, Kana Okamoto, Shunsuke Kobayashi, Yoshinobu Ishitobi, Taiga Ninomiya, Jotaro Akiyoshi

“…As exposure therapy, she was asked to view the images associated with these symptoms three times a day along with drug therapy. With the combination of drug and exposure therapies, her obsessive-compulsive symptoms improved within 6 months, with no interference in her daily life. …”
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Pelvic Inflammatory Disease: Possible Catches and Correct Management in Young Women by Chiara Di Tucci, Daniele Di Mascio, Michele Carlo Schiavi, Giorgia Perniola, Ludovico Muzii, Pierluigi Benedetti Panici

“…Despite guidelines for management of PID, the right timing to switch to surgical therapy is not clear. …”
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Sleep-driven prefrontal cortex coordinates temporal action and multimodal integration by Ahmed Z. Ibrahim, Kareem Abdou, Masanori Nomoto, Kaori Yamada-Nomoto, Reiko Okubo-Suzuki, Kaoru Inokuchi

“…Chemo-genetic inhibition verified that PrL is required for proper signal response and action timing. These findings emphasize that sleep and cortical activity are keys for cognitive flexibility in adapting to different modalities.…”
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Influence of Different Disinfectants on Surface Hardness of Heat-Polymerized Acrylic Resins utilized for Orthodontic Appliance by Wael Abdul Alrazzaq Alwaeli, Mohammed Abdul Sattar Alsegar

“…All specimens were tested via a hardness tester three times and the average reading was measured for all specimens. …”
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Integrated-Hybrid Framework for Connected and Autonomous Vehicles Microscopic Traffic Flow Modelling by Ammar Jafaripournimchahi, Yingfeng Cai, Hai Wang, Lu Sun, Jiancheng Weng

“…Our numerical results demonstrated that the IH model can capture the velocity fluctuations, delay times, and kinematic waves efficiently in traffic flow.…”
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Quantitative Influence Analysis of the Development Scale of Market Economy on the Level of Music Innovation by Yang Li, Qiuyi Zhang, Tianzhuo Gong

“…Music art is a form of conveying cultural information and humanistic emotions. From ancient times to the present, the form of music has undergone great changes. …”
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Gonad quality of sea urchin Tripneustis gratilla with different seaweed diets by Agnette Tjendanawangi, Nicodemus Dahoklory

“…Each treament was repeated three times. Measured parameters were gonad weight, gonad maturity index, gonad color quality, and gonad texture.  …”
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Vehicle Detection in Different Environments by Mohsen Valizadehasl, Mohammad Badpeima, Sahar Khosraviyan Zahedani

“…The proposed approach is mainly focused on designing the system which is applicable in the case of different weather conditions (rainy, snowy, misty etc), different times during the day and night (daylight, night, noon, afternoon), heavy traffics, the existence of the shadows and different road conditions. …”
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Integrative analysis of the Aachen geothermal system (Germany) with an interdisciplinary conceptual model by Esteban Gómez-Díaz, Andrea Balza Morales, Peter A. Kukla, Maren Brehme

“…We provide a first approach to comprehending the geologically complex geothermal system in the Aachen area, which has been known for its natural thermal spring occurrences since Roman times. Through a comprehensive analysis involving geochemical interpretation of water samples, a review of 2D seismic profiles, stress analysis, and surface geology, a dynamic model has been built, which serves as a conceptual framework providing a clearer understanding of the system. …”
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Interdisciplinary relationships between Health Education and Universal Literature by Míriam Gutiérrez Escobar, Felicia Margarita Llerena Bermúdez, Lourdes González Pérez, José Carlos Medina Alejo, María Bello Benet, Anisley Cazañas Hernández

“…Current and important topics were addressed: collective - personal hygiene and sexual education, by selecting work fragments from different countries and times, from Greco-Latin culture until to the nineteenth century; didactic guides are presented which make it possible to enrich and deepen the study of a work beyond an exclusively literary perspective, contributing to increase health education and strengthen interdisciplinary links. …”
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Maxillofacial fractures in patients treated at the Princess Marina Hospital, Gaborone by Juan Carlos Quintana Díaz, Carlos Alberto Botella Suarez, Evis Johnson Montero, Raquel Rojas Bruzón

“…The etiology is varied, and requires fast, accurate, and timely diagnosis and treatment. The study of this entity is relevant to know its characteristics as part of emergency care; as well as its clinical and social implications.…”
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Flexibility estimation of electric vehicles and its impact on the future power grid by Jiexiang Wu, Li Li, Jiangfeng Zhang, Boyi Xiao

“…Two models are developed to evaluate electric vehicle owners’ willingness to participate in both non-vehicle-to-grid and vehicle-to-grid scenarios, providing insights into future peak demand increases and potential reductions through optimization.A case study in Texas, USA, utilizing data from the Pecan Street database, reveals that by 2030, the increase in peak electric vehicle charging demand could exceed the current levels by over 4.7 times. This surge is up to 3.16% of the total electricity demand in Texas. …”
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Clinical characteristics, diagnosis, treatment, and prognosis of Atezolizumab-induced encephalitis, aseptic meningitis or meningoencephalitis by Qingzi Yan, Yixiang Hu, Xiang Liu, Hong Xia

“…Therefore, clinical practitioners should have a deep understanding of these neurological immune-related adverse events, promptly diagnose them, and provide accurate and timely treatment.…”
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Resistant Starch Contents of Native and Heat-Moisture Treated Jackfruit Seed Starch by Ornanong S. Kittipongpatana, Nisit Kittipongpatana

“…The effect of the conditions was tested at varied moisture contents (MC), temperatures, and times. Moisture levels of 20–25%, together with temperatures 80–110°C, generally resulted in increases of RS amount. …”
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Assessment of Malaria Predisposing Factors among Crop Production Farmers Attending the Ndop District Hospital, Northwest Region of Cameroon by Nfor Omarine Nlinwe, Tamombi Akonji Emmanuel Ateh

“…Malaria causes manpower loss when it strikes farmers at critical planting, weeding, and harvesting times. Given the above, the expected outcome to malaria prevention programs in farming communities remains a far cry, especially where the predisposing factors are not properly identified and long-lasting solutions proffered. …”
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Experimental Study on Failure Law and Mechanism of Red Sandstone under Ultrasonic Vibration Excitation by Jiyao Wang, Xufeng Wang, Xuyang Chen, Liang Chen, Zhanbiao Yang, Zechao Chang, Lei Zhang, Zhijun Niu

“…The apparent resistivity became as high as 320000 Ω being 16 times the initial resistivity. The fracture propagated downwards as deep as 41 mm. …”
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Dialogic theology of missions as a response to the global refugee phenomenon by Shakespeare Sigamoney, Samuel K.B. Nkrumah-Pobi

“…The legacies of colonialism on both the colonised and coloniser is one thing that our world cannot escape in contemporary times. In most of the places, colonialism came with its own form of Christianity. …”
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Knowledge integration capability, innovativeness, and entrepreneurial orientation on business performance by Helisia Margahana, Dyah Sugandini

“…The more SMEs that have a strong entrepreneurial orientation can integrate the knowledge of their employees and have the ability to adopt innovation (innovativeness) quickly, SMEs can improve their performance, even in difficult times due to the COVID-19 pandemic. Research limitations/implications – This study only observed SMEs that survived the COVID-19 pandemic and did not involve SME respondents who failed to adapt to the pandemic. …”
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Angle Closure Glaucoma in Retinitis Pigmentosa by Chandni Pradhan, Simanta Khadka, Purushottam Joshi

“…However, this can be prevented by thorough clinical examination and timely intervention in those susceptible eyes.…”
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