Early empiric anti-Mycobacterium tuberculosis therapy for sepsis in sub-Saharan Africa: a protocol of a randomised clinical trial by Mark Conaway, David R Boulware, Scott K Heysell, Stellah G Mpagama, Christopher C Moore, Alphonce Liyoyo, Conrad Muzoora, Catherine Gitige, Bibie Said, Edwin Nuwagira, Rinah Arinaitwe, Rhina Mushagara, Peter Buzaare, Anna Chongolo, Samuel Jjunju, Precious Twesigye, Megan Null, Tania A Thomas

“…A sample size of 436 participants will provide 80% power for testing each of the main effects of timing and dose on 28-day mortality with a two-sided significance level of 5%. …”
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FTACMT study protocol: a multicentre, double-blind, randomised, placebo-controlled trial of faecal microbiota transplantation for autism spectrum disorder by Li Ling, Wei Wei, Li Lin, Li Ke, Ye Chen, Li Ning, Wang Yu, Zhang Xin, Yang Rong, Zhang Xueying, Cui Jiaqu, Chen Qiyi, Qin Huanlong, Du Yasong, Zhao Xiaoxin, Lu Jubao, Lv Xiaoqiong, Ma Chunlian, Chen Shidong, Kuang Guifang, Zhao Dongmei, Fang Shuanfeng, Zhang Xujing, Yang Binrang, Wang Yanxia, Yuan Song, Zhou Xiang, Zhang Beihua, Jiang Lin, Ji Hong, Yan Yinmei, Yan Peihua, Huang Linsheng, Zhang Shaoyi, Ma Chenhuan, Miao Yun, Ling Wenqi, Geng Bojing, Feng Xueying, Li Huilin, Liu Liyan, Wu Weijia, Li Dexin, Jiang Qianru

“…Children aged 3–6 years will take two capsules two times a day, and those older than 6 years will take three capsules two times a day. …”
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Can Caffeine Be an Effective Ergogenic Aid in Combat Sports? A Comprehensive Review by Marcin Komorowski, Michał Janiszewski, Aleksandra Pelczarska, Rafal Kaczorowski, Tomasz Forenc, Jaromir Hunia, Julia Górny, Jonasz Jurek, Alicja Kapciak

“…Doses ranging from 3–6 mg/kg were found to improve strength, endurance, and reaction times across various combat sports, with higher doses being more effective for elite athletes. …”
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Heterochrony in orthodenticle expression is associated with ommatidial size variation between Drosophila species by Montserrat Torres-Oliva, Elisa Buchberger, Alexandra D. Buffry, Maike Kittelmann, Genoveva Guerrero, Lauren Sumner-Rooney, Pedro Gaspar, Georg C. Bullinger, Javier Figueras Jimenez, Fernando Casares, Saad Arif, Nico Posnien, Maria D. S. Nunes, Alistair P. McGregor, Isabel Almudi

“…When otd expression is driven prematurely during D. melanogaster eye development, the ommatidia grow larger, supporting a possible role for the timing of otd expression in regulating ommatidial size. …”
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Lattice-based interpenetrating phase composite metamaterial fabricated with hybrid material extrusion process for tunable mechanical properties by Ritik Raj, Jung-Ting Tsai, Mayur Jiyalal Prajapati, Jeng-Ywan Jeng

“…IPC-type I demonstrated a substantial improvement in mechanical performance, exhibiting a compressive strength up to 5 times higher and an energy absorption per unit volume up to 2.5 times greater than empty or single-phase metamaterials. …”
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The Combination of Intravenous Immunoglobulin, Dexamethasone, and a High Dose of Mononuclear Cells Transfusion: An Effective Strategy for Decreasing Donor-Specific Antibodies Durin... by Xiaoping Li, Yu Li, Dingsong Zhang, Xiaozhuang Hu, Lin Liu, Zhongtao Yuan, Shiqi Li, Yancheng Dong, Yingnian Chen, Sanbin Wang

“…The kinetics of DSAs at different times and the engraftment and transplantation outcomes were also observed. …”
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Effect of Ti content on spinodal decomposed microstructure and properties of AlCoCrFeNiTix high-entropy alloy coatings prepared by laser cladding by Kun Yue, Xiaoqin Yang, Lin Wang, Liji Su, Quan Xu, Zhe Xu, Chunlong Cheng, Yeqing Wang, Zhijun Wang, Zheng Chen

“…The hardness of AlCoCrFeNiTi1 coating reached 828.35 HV0.1, which was 56.29 times higher than that of the AlCoCrFeNi coating, while its wear resistance was 80.7 times greater. …”
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Development of a Novel Co-Amorphous Curcumin and L-Arginine (1:2): Structural Characterization, Biological Activity and Pharmacokinetics by Jose Antonio Mancillas-Quiroz, Miriam del Carmen Carrasco-Portugal, Karina Mondragón-Vásquez, Juan Carlos Huerta-Cruz, Juan Rodríguez-Silverio, Leyanis Rodríguez-Vera, Juan Gerardo Reyes-García, Francisco Javier Flores-Murrieta, Jorge Guillermo Domínguez-Chávez, Héctor Isaac Rocha-González

“…The bioavailability of free plasmatic curcumin increased about 22.4 times when it was given as CAC12 relative to a phytosome formulation at the equivalent dose. …”
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Advanced process control in laser-based powder bed fusion–Smart Fusion feedback-loop control as a path to uniform properties for complex structures? by Florian Nahr, Tobias Novotny, Dominik Kunz, Ulrich Kleinhans, Lova Chechik, Dominic Bartels, Michael Schmidt

“…However, changes in cross-sectional area with build height influence inter-layer times and heat dissipation, resulting in potential local overheating. …”
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Prediction of microvascular obstruction from angio-based microvascular resistance and available clinical data in percutaneous coronary intervention: an explainable machine learning... by Zhe Zhang, Yang Dai, Peng Xue, Xue Bao, Xinbo Bai, Shiyang Qiao, Yuan Gao, Xuemei Guo, Yanan Xue, Qing Dai, Biao Xu, Lina Kang

“…Although we observed the inconsistency between AMR and MVO but the ML-based construction of MVO prediction model is feasible, which brings the possibility of timely prediction of patients with MVO and timely imposition of interventions during PPCI.…”
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Tear film lipid layer thickness and blink dynamics in patients with blepharospasm by Ji-Sun Paik, Min Jeong Kwon, Ga Hee Nam, Kyungdo Han, Woong-Joo Whang, Ho Sik Hwang, Suk-Woo Yang, Hyun-Seung Kim, Kyung Sun Na, Won-Kyung Cho

“…When comparing blink dynamics, complete blink rate was significantly higher in the pre-injection BEB group compared to the DED group (5.25 ± 4.32 times/20 s vs. 2.43 ± 2.82 times/20 s, p = 0.0055). …”
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The role of adipose tissue cell elements in the regulation of the nitroxidergic system and possible ways of pharmacological modulation by I. F. Bielenichev, S. O. Maslennikov, N. V. Dobrelia, O. S. Khromov, M. L. Holovakha, V. P. Ryzhenko, O. O. Brek

“…The PA and IPA with PVAT responded to acute hypoxia with vasoconstriction – an increase in the amplitude of contraction in the first and second phases, and after removing PVAT, they responded with a decrease in the maximum amplitude of contraction by 3.4 times in the 1st phase and an increase in amplitude by 1.8 times in the 2nd phase. …”
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The Beliefs, Myths, and Reality Surrounding the Word Hema (Blood) from Homer to the Present by John Meletis, Kostas Konstantopoulos

“…Greek scientific considerations about blood date from Homeric times. The ancient Greeks considered hema as synonymous with life. …”
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``Prenatally diagnosed gastroschisis: A case report'' by Sakshi Dudhe, MBBS, Devyansh Nimodia, MBBS, Gaurav V. Mishra, MD, Pratapsingh Hanuman Parihar, MD, Anjali Kumari, MBBS, Rishitha Kotla, MBBS

“…This anomaly presents considerable challenges in neonatal management, thereby necessitating timely and effective surgical intervention.Categories: Gynaecology, Radiology, Obstetric, Surgery.…”
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Study on Quantitative Phase Imaging by Dual-Wavelength Digital Holography Microscopy by Lin Hu, Yunxiu Shui, Yaohui Dai, Haiyu Wu, Gang Zhu, Yan Yang

“…The results of numerical simulation and optical experiments demonstrated that the reconstructed speed increased by 37.9 times, and the relative error of measurement is 4% compared with the traditional holographic microscopy system. …”
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High Altitude Pulmonary Edema. Case Report and Bibliography Review by Edgar Ernesto Romo Pinos, Yojan Guevara Pérez, Rina María Idrovo Avecillas, Vilma Silvana Vele Quito

“…The objective of this report is to know the pathophisiology, diagnostic and therapeutic approach of high altitute pulmonary edema since it is a frequent condition in children of the region and it is unknown by many health professionals. Most of the times it is under diagnosed or confused with other pathologies which present with respiratory failure.…”
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IgA Monoclonal Gammopathy of Undetermined Significance and Complication of Streptococcus mitis Bacteremia by Jennifer Paterno, Alessandra Petrillo, David Samuel Dicapua Siegel, Chinwe Ogedegbe

“…Recent studies parallel this case by showing MGUS patients may have two times the risk of infections compared to the unaffected population. …”
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The presence of Pentecostalism in social movements: a case study with a psychosocial approach by Raul Gomes de Almeida, Bernardo Parodi Svartman

“…The church also provides a parallel dimension of engagement and participation that, at times, competes with the direct participation in the struggle for rights. …”
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Multiloop Parallelisation Using Unrolling and Fission by Yuet Ming Lam, José Gabriel F. Coutinho, Chun Hok Ho, Philip Heng Wai Leong, Wayne Luk

“…Experimental results show that a maximum speedup of 34 is achieved on a 274 MHz FPGA for the N-Body over a 2.6 GHz microprocessor, which is 4.1 times higher than that of an approach without unrolling.…”
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HisCoM-PAGE: software for hierarchical structural component models for pathway analysis of gene expression data by Lydia Mok, Taesung Park

“…We expect that the HisCoM-PAGE software will make our method more easily accessible to researchers who want to perform pathway analysis for survival times.…”
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