Impact of Preoperative and Intraoperative Factors on Postoperative Outcomes in Patients with Colorectal Cancer: A 10-Year Retrospective Study by Lucian Flavius Herlo, Ioana Golu, Alexandra Herlo, Claudia Raluca Balasa Virzob, Ionescu Alin, Stela Iurciuc, Ionut Eduard Iordache, Luana Alexandrescu, Doina Ecaterina Tofolean, Raluca Dumache

“…Intraoperative factors such as blood loss greater than 500 mL (<i>p</i> < 0.001) and longer operative time (<i>p</i> = 0.021) were also significant predictors of adverse outcomes. …”
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Good-Quality mHealth Apps for Endometriosis Care: Systematic Search by Diksha Sirohi, Cecilia HM Ng, Niranjan Bidargaddi, Helen Slater, Melissa Parker, M Louise Hull, Rebecca O'Hara

“…Few eHealth websites scored well on therapeutic persuasiveness (6/19, 31.6%), therapeutic alliance (9/19, 47.4%), and general subjective evaluation (6/19, 31.6%). ConclusionsAlthough time and geographical location can influence the search results, we identified 6 “good-quality” endometriosis mHealth apps that can be recommended to the endometriosis community. mHealth apps designed for community use should evaluate their effectiveness on user’s endometriosis knowledge, self-recommended management strategies, pain self-efficacy, user satisfaction, and user quality of life. …”
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The methyl-CpG binding domain 2 regulates peptidylarginine deiminase 4 expression and promotes neutrophil extracellular trap formation via the Janus kinase 2 signaling pathway in e... by Biao Peng, Mu-Yun Yan, Yun-Rong Chen, Fei Sun, Xu-Dong Xiang, Da Liu

“…Flow cytometry was employed to determine the percentages of Th2, Th17, and Treg cells in lung tissues. Quantitative real-time polymerase chain reaction was utilized to assess the mRNA expression levels of MBD2, JAK2, and PAD4. …”
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Elucidating epigenetic landscape of gastric premalignant lesions through genome‐wide mapping of 5‐hydroxymethylcytosines: A 12‐year median follow‐up study by Zhongguang Luo, Wenshuai Li, Wanwei Zheng, Yixiang Shi, Maolin Ye, Xiangyu Guo, Kaiyi Fu, Changsheng Yan, Bowen Wang, Bin Lv, Shaocong Mo, Hongyang Zhang, Jun Zhang, Chuan He, Feifei Luo, Wei Zhang, Jie Liu

“…Methods To our knowledge, we conducted the largest and longest longitudinal study of a Chinese population with gastric precursor lesions, involving 29,176 patients with gastritis who underwent gastroscopy and biopsy between 2001 and 2015, with follow‐up until 1 August, 2022. The median follow‐up time was 12.2 years, and the overall GAC incidence rate was 0.82%. …”
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Induced hepatocyte-like cells derived from adipose-derived stem cells alleviates liver injury in mice infected with Echinococcus Multilocularis by Hui Liu, Xiaojuan Bi, Ning Yang, Xue Zhang, Bingbing Fang, Nuerbaiti Kusuman, Wenmei Ma, Jing Li, Jin Chu, Li Sun, Liang Li, Guodong Lü, Renyong Lin

“…The iHEPs exhibit morphological features and a glycogen storage function similar to those of mature hepatocytes and demonstrate an upregulation in hepatic gene programs with increasing induction time. Following transplantation, iHEPs were observed surrounding the metacestode lesions in the liver parenchyma of E. multilocularis-infected mice. iHEPs transplantation effectively restored liver function and improved liver injury in the infected mice. …”
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Isocitrate Dehydrogenase 1 and 2 Mutations in Pediatric Neuroblastoma Patients by Emre LEVENTOGLU, Gurses SAHIN, Sule YESIL, Ceyhun BOZKURT, Nazmiye YUKSEK, Ali FETTAH, Sule TOPRAK, Burcak KURUCU BILGIN, Emre CAPKINOGLU, Nilgun EROGLU, Sibel AKPINAR TEKGUNDUZ, Ayse Ulya ERTEM

“…Conclusions: This study demonstrated the relationship between neuroblastoma and IDH mutation for the first time. Because to the fact that the mutation is very heterogeneous, it would be appropriate to conduct a larger series of patients in terms of the impact of the clinical significance of each mutation on the diagnosis and prognosis.…”
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Extracellular vesicles-derived miR-21 as a biomarker for early diagnosis and tumor activity in breast cancer subtypes by Claudia Omarini, Virginia Catani, Ilenia Mastrolia, Angela Toss, Federico Banchelli, Chrystel Isca, Daniele Medici, Ornella Ponzoni, Marco Brucale, Francesco Valle, Maria Cristina Baschieri, Roberto D’Amico, Valentina Masciale, Chiara Chiavelli, Federica Caggia, Carlo Augusto Bortolotti, Federico Piacentini, Massimo Dominici

“…The levels of miR-21 in EVs was evaluated using real time PCR and compared between groups (EBC, MBC and FU vs. …”
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Dynamic Tracking Human Mesenchymal Stem Cells Tropism following Smoke Inhalation Injury in NOD/SCID Mice by MeiJuan Song, Qi Lv, XiuWei Zhang, Juan Cao, ShuLi Sun, PeiXin Xiao, ShiKe Hou, Hui Ding, ZiQuan Liu, WenLong Dong, JinQiang Wang, Xue Wang, ZhiGuang Sun, Man Tian, HaoJun Fan

“…In both the uninjured and SII mice, the BLI signals in the lungs steadily decreased over time and disappeared by 5 days after treatment. hBMSCs significantly attenuated lung injury, elevated the levels of KGF, decreased the levels of TNF-α in BALF, and inhibited inflammatory cell infiltration in the mice with SII. …”
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Poly (ADP-ribose) (PAR) levels in Peripheral Blood Mononuclear Cells (PBMC) during peri-implantation and early pregnancy in buffalo cows by Giovanna De Matteis, Anna Reale, Michele Zampieri, Emanuela Rossi, Federica Signorelli, Olimpia Barbato, Vittoria Lucia Barile

“…The repeated measures ANOVA tested differences in mean values across time points and between experimental groups. This is the first study that evaluates PAR levels in bubaline PBMC during peri-implantation and early pregnancy. …”
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Thermodynamic properties of iron, aluminum, boron and phosphorus in dilute silicon solutions by molecular interaction volume model by Li S.-Y., Liu K., Yang F., Xi F.-S., Wu J.-J., Ma W.-H., Lei Y., Wang Y.-J., Zhang X.-N.

“…The self-interaction parameters (εi,i) for Si-i system were obtained as εB,B= -2.728-362.031/T, εAl,Al = 2.157-1876.776/T, εFe,Fe= -4.842+14445.926/T and εP,P = -2.543+13767.036/T. At the same time, the interaction parameters among components B, Al, and Fe in dilute ternary Sii- j solutions were also derived as εFe,B=-1.2758-2946.306/T, εAl,B = 0.7467-9765.9298/T and εFe,Al= -1.39677+3319.6803/T. …”
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Extensive Atrophic Gastritis Increases Intraduodenal Hydrogen Gas by Yoshihisa Urita, Toshiyasu Watanabe, Tadashi Maeda, Tomohiro Arita, Yosuke Sasaki, Takamasa Ishii, Tatsuhiro Yamamoto, Akiro Kugahara, Asuka Nakayama, Makie Nanami, Kaoru Domon, Susumu Ishihara, Hirohito Kato, Kazuo Hike, Norikok Hara, Shuji Watanabe, Kazushige Nakanishi, Motonobu Sugimoto, Kazumasa Miki

“…Studies were performed in 647 consecutive patients undergoing upper endoscopy. At the time of endoscopic examination, we intubated the stomach and the descending part of the duodenum without inflation by air, and 20 mL of intraluminal gas samples of both sites was collected through the biopsy channel. …”
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Kefir Prevents Adipose Tissue Growth Through the Induction of Apoptotic Elements in High-Fructose Corn Syrup-Fed Rats by Esra Aslan, Gokhan Sadi, Hilal Guzel, Cigdem Karaca, Omer Adil Korkmaz, Mine Kanat Pektas, Mehmet Celegen, Tugce Aladag, Seyma Oncu, Mehmet Bilgehan Pektas

“…Gene expressions were evaluated with semi-quantitative real-time polymerase chain reaction (qRT-PCR). The indirect terminal deoxynucleotidyl transferase dUTP nick-end labeling (TUNEL) method was used to assess changes in apoptotic cells, and hematoxylin/eosin staining to determine adipocyte number and diameter. …”
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TMEM187-IRAK1 Polymorphisms Associated with Rheumatoid Arthritis Susceptibility in Tunisian and French Female Populations: Influence of Geographic Origin by Olfa Khalifa, Nathalie Balandraud, Nathalie Lambert, Isabelle Auger, Jean Roudier, Audrey Sénéchal, David Geneviève, Christophe Picard, Gérard Lefranc, Isabelle Touitou, Bakridine M’Madi Mrenda, Cécilia Benedito, Etienne Pardoux, Anne-Laure Gagez, Yves-Marie Pers, Christian Jorgensen, Touhami Mahjoub, Florence Apparailly

“…Our results replicated for the first time the association of the three Xq28 polymorphisms with RA risk in Tunisian and French populations and suggested that RA susceptibility is associated with TMEM187-IRAK1 polymorphisms in women. …”
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Metabolic resistance to pyrethroids with possible involvement of non-coding ribonucleic acids in Anopheles funestus, the major malaria vector in western Kenya by Isaiah Debrah, Daibin Zhong, Maxwell G. Machani, Godfrey Nattoh, Kevin O. Ochwedo, Collins M. Morang’a, Ming-Chieh Lee, Linda E. Amoah, Andrew K. Githeko, Yaw A. Afrane, Guiyun Yan

“…Conclusion This study unveils the molecular basis of insecticide resistance in An. funestus in western Kenya, highlighting for the first time the potential role of non-coding RNAs alongside metabolic detoxification in pyrethroid resistance. …”
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Le mouvement étudiant et la question des langues en Algérie (1962-1965) : à propos d’un épisode méconnu de l’histoire de l’UGEMA-UNEA by Yassine Temlali

“…In reconstructing this obscure episode in the light of many sources, including the accounts of participants, this article explores the attitude of the student movement, in the immediate post-independence period (1962–1965), to the question of Berber languages, which were spoken by a fifth of the population but which at the time enjoyed no explicit juridical status. It looks more generally at the positions of this movement on the linguistic problem in Algeria in a context in which the promotion of the “national language”, Arabic, had to reckon with the first questioning of the Arabo-Islamic unanimity imposed by the need for unity against the French occupier.I suggest that the burial of these proposals in favour of Berber languages should be interpreted in the light of the cultural doctrine of the Algerian Communist Party (PCA), then dominant within the framework of the UGEMA, and its general attitude towards the “socialist” regime of Ahmed Ben Bella. …”
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Geometrical Features of Subbasal Corneal Whorl-like Nerve Patterns in Dry Eye Disease by Ziqing Feng, MD, Kang Yu, MD, Yupei Chen, MS, Gengyuan Wang, MS, Yuqing Deng, MD, Wei Wang, MD, Ruiwen Xu, MD, Yimin Zhang, MD, Peng Xiao, PhD, Jin Yuan, MD, PhD

“…Whorl-like nerve metrics correlated with ocular discomfort, tear film break-up time, tear secretion, and corneal fluorescein staining, respectively (P < 0.05). …”
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The impact of the live broadcast of Stromae’s song L’enfer on social media publications, calls to the national helpline, and suicide attempt rates in France by Charles-Edouard Notredame, Chloé Saint-Dizier, Antoine Lamer, Erika Nogue, Emile Fares, Mohamed Lemdani, Guillauma Vaiva, Philippe Courtet, Emilie Olié

“…We employed the Gombay test to identify change points within each time series. We identified a significant increase in mean SA rates among women aged 20–24 years 6 days after the singer’s performance. …”
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Avascular necrosis in pediatric rheumatic diseases: an Italian retrospective multicentre study by Ivan Taietti, Federico Zini, Emilio Amleto Conti, Enrica Cristini, Irene Borzani, Giulia Ramponi, Claudia Bracaglia, Raffaele Pecoraro, Riccardo Papa, Jessica Tibaldi, Serena Pastore, Gabriele Simonini, Marco Cattalini, Antonella Meini, Achille Marino, Stefano Lanni, Francesca Minoia, Giovanni Filocamo

“…Population collected was further evaluated according to the different underlying rheumatologic disease and to the time of AVN onset. Results Fourteen patients (SLE = 7; JIA = 4; others = 3) were collected from 7 centres. …”
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Improving Autonomous Vehicle Cognitive Robustness in Extreme Weather With Deep Learning and Thermal Camera Fusion by Mehmood Nawaz, Sheheryar Khan, Muhammad Daud, Muhammad Asim, Ghazanfar Ali Anwar, Ali Raza Shahid, Ho Pui Aaron HO, Tom Chan, Daniel Pak Kong, Wu Yuan

“…The object detection framework uses the modified version of the YoloV8 model, which exhibits high accuracy in real-time detection. In the YoloV8 model, we adjusted the network architecture to incorporate additional convolutional layers and altered the loss function to enhance detection accuracy in foggy and rainy conditions. …”
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Exploring the Effects of Sleep Deprivation on Physical Performance: An EEG Study in the Context of High-Intensity Endurance by Shanguang Zhao, Majed M. Alhumaid, Hai Li, Xin Wei, Steve SHYH-Ching Chen, Hongke Jiang, Yuwu Gong, Yun Gu, Haiquan Qin

“…After high-intensity endurance exercise, the SD condition had a higher maximum heart rate (p < 0.05) and shorter exercise time (p < 0.05) than normal sleep. Compared with before exercise, the δ band in the left parietal lobe P7 channel increased significantly (p < 0.01), and the θ band in the central Cz channel and the left and right parietal lobe P7 and P8 channel increased significantly (p < 0.01 & p < 0 0.05) in SD and normal sleep conditions after exercise. …”
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