Genetics and biological characteristics of duck reoviruses isolated from ducks and geese in China by Xiaohong Sun, Jing Guo, Jinyan Shen, Mengdi Guan, Lili Liu, Yujiao Xie, Hongke Xu, Mengjing Wang, Anran Ren, Wenxi Li, Feng Cong, Xuyong Li

“…Lethal infection with highly pathogenic viruses causes severe focal necrosis and hemorrhage in the liver, spleen, bursa of Fabricius and thymus, resulting in high mortality in inoculated birds. …”
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Floristic novelties in the context of interdisciplinary studies by N. P. Stepanyan-Gandilyan, R. A. Hovsepyan

“…., Salvia nemorosa L., Thymus eriophorus Ronn., Th. transcaucasicus Ronn., Tripleurospermum caucasicum (Willd.) …”
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Migration, Distribution, and Safety Evaluation of Specific Phenotypic and Functional Mouse Spleen-Derived Invariant Natural Killer T2 Cells after Adoptive Infusion by Dongzhi Chen, Wenbin Xu, Jingfang Teng, Huifang Liu, Yuanyuan Wang, Yan Wang, Shujie Cheng, Ming Meng

“…The adoptive infusion of iNKT cells into healthy mice resulted in no significant change in the basic life status of mice compared with the noninjected group. iNKT cells were detected in the lung, spleen, and liver, but no fluorescence was detected in lymph nodes and thymus. After dissecting the mice, it was found that there were no significant abnormalities in the relevant immune organs, brain, heart, kidney, lung, and other organs. …”
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Prenatal diagnosis of mucopolysaccharidosis type I on hepatosplenomegaly and coarse features: a case-report by Maxime Agranier, Florence Demurger, Christele Dubourg, Jerome Fromageot, Anne-Sophie Cabaret Dufour, Erika Launay, Magalie Gournay, Charles Lefèvre, Roseline Froissart, Magali Pettazzoni, Paul Rollier

“…Case presentation A pregnant woman at 26.5 gestational weeks was referred to our center for fetal ultrasound findings of hepatosplenomegaly, distinct facial features, and liver, spleen and thymus echogenic spots. Whole exome sequencing after amniocentesis identified two likely pathogenic IDUA gene variants (in trans), raising suspicion of a diagnosis of MPS I. …”
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Synthesis, DNA-Binding, Anticancer Evaluation, and Molecular Docking Studies of Bishomoleptic and Trisheteroleptic Ru-Diimine Complexes Bearing 2-(2-Pyridyl)-quinoxaline by Sofia Balou, Athanasios Zarkadoulas, Maria Koukouvitaki, Luciano Marchiò, Eleni K. Efthimiadou, Christiana A. Mitsopoulou

“…Various spectroscopic techniques were employed to investigate the interaction of both complexes with calf thymus DNA (CT-DNA). The experimental data were confirmed by molecular docking studies, employing two different DNA sequences. …”
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Normal Thymic Size and Low Rate of Infections in Human Donor Milk Fed HIV-Exposed Uninfected Infants from Birth to 18 Months of Age by Dorthe Lisbeth Jeppesen, Annette Kjær Ersbøll, Tine Ursula Hoppe, Susanne Dam Nielsen, Niels Henrik Valerius

“…HIV-EU infants fed human donor milk have normal growth of thymus and contract fewer infections than other healthy infants. …”
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Fermented Lentinus edodes extract containing α-glucan ameliorates concanavalin A-induced autoimmune hepatitis in mice by Xin Hu, Dan Cheng, Yingxia Zhang, Po Li, Xiaoping Wu, Junsheng Fu

“…The results showed that compared with the model group, the level of proinflammatory cytokines in serum of FLA pretreated mice was significantly decreased, and the degree of inflammatory cell infiltration in liver, thymus and spleen was significantly reduced. Quantitative polymerase chain reaction, immunohistochemistry, and Western blotting showed that FLA pre-treatment inhibited the ConA-induced apoptosis of hepatocytes by down-regulating the expression of BAX and up-regulating the expression of BCL-2. …”
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Pre-T cell receptor-α immunodeficiency detected exclusively using whole genome sequencing by Daniele Merico, Nigel Sharfe, Harjit Dadi, Bhooma Thiruvahindrapuram, Jill de Rijke, Zakia Dahi, Mehdi Zarrei, Abdulrahman Al Ghamdi, Azhar Al Shaqaq, Linda Vong, Stephen W. Scherer, Chaim M. Roifman

“…Abstract Maturation of αβ lineage T cells in the thymus relies on the formation and cell surface expression of a pre-T cell receptor (TCR) complex, composed of TCRβ chain and pre-TCRα (pTCRα) chain heterodimers, giving rise to a diverse T cell repertoire. …”
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Impact of Bifidobacterium longum NSP001 on DSS-induced colitis in conventional and humanised mice by Menglin Chen, Hong Yao, Huizi Tan, Wenqi Huang, Quanyong Wu, Shaoping Nie

“…Disorders in disease activity index (DAI), morphology and histology of colon tissue, intestinal permeability, and secretion of MPO, TNF-α and IL-6 were ameliorated by daily intake of live B. longum NSP001 cells in both conventional and humanised colitis mice. But the abnormal thymus index, and colonic production of ZO-1 and iNOS were improved only in colitis mice treated with B. longum NSP001 and humanised microbiome. …”
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Systemic and immunotoxicity induced by topical application of perfluoroheptane sulfonic acid (PFHpS) or perfluorooctane sulfonic acid (PFOS) in a murine model by Lisa M. Weatherly, Hillary L. Shane, Laurel G. Jackson, Ewa Lukomska, Rachel Baur, Madison P. Cooper, Stacey E. Anderson

“…PFHpS induced significantly increased relative liver weight, significantly decreased relative spleen and thymus weight, altered serum chemistries, and altered histopathology. …”
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Spermidine alleviates thymopoiesis defects and aging of the peripheral T-cell population in mice after radiation exposure by Kengo Yoshida, Zhenqiu Liu, Yoshiko Kubo, Masahiko Miura, Mika Yamaoka, Hiroko Nagamura, Munechika Misumi, Yoichiro Kusunoki

“…The numbers of total, double-positive, and single-positive thymocytes were decreased by irradiation, whereas none were decreased in the irradiated mice treated with SPD. RNA sequencing of thymus cells revealed 803 upregulated genes in irradiated mice compared with those in non-irradiated control mice, with these genes enriched in leukocyte activation and inflammatory cytokine production. …”
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Nr4a1 and Nr4a3 redundantly control clonal deletion and contribute to an anergy-like transcriptome in auto-reactive thymocytes to impose tolerance in mice by Hailyn V. Nielsen, Letitia Yang, James L. Mueller, Alexander J. Ritter, Ryosuke Hiwa, Irina Proekt, Elze Rackaityte, Dominik Aylard, Mansi Gupta, Christopher D. Scharer, Mark S. Anderson, Byron B. Au-Yeung, Julie Zikherman

“…Abstract The Nr4a nuclear hormone receptors are transcriptionally upregulated in response to antigen recognition by the T cell receptor (TCR) in the thymus and are implicated in clonal deletion, but the mechanisms by which they operate are not clear. …”
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Results of experimental infection of vaccinated and non-vaccinated ducklings with duck hepatitis virus by A. A. Chesnokova, E. V. Ivanova, V. V. Pronin, O. A. Chupina, V. Yu. Fomenko, M. S. Volkov, V. N. Irza

“…Pathomorphological studies carried out post experimental infection indicate that duck hepatitis virus induces pathogenic effect not only in birds’ digestive organs (the liver, in particular) but also causes degenerative changes in central and peripheral immune organs: in cloacal bursa, thymus and third eyelid gland, that may be manifested as deficiency of B- and T-cell immunity and requires further studies. …”
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A phytotherapeutic approach to hinder the resistance against clindamycin by MRSA: in vitro and in silico studies by Amal Mayyas, Ali Al-Samydai, Nehaya Al-Karablieh, Waleed A Zalloum, Deniz Al-Tawalbeh, Farah Al-Mamoori, Rula A. Amr, Hamdi Al Nsairat, Simone Carradori, Lidia Kamal Al-Halaseh, Talal Aburjai

“…A synergistic test with clindamycin was performed, and molecular docking studies evaluated the interaction between a key compound (trans-cinnamaldehyde) and MRSA protein.Results EOs from Cinnamomum verum, Rosmarinus officinalis, Salvia officinalis, and Thymus vulgaris demonstrated significant inhibitory and synergistic activities against MRSA, standard strain, and human clinical isolates. …”
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A Cornflower Extract Containing N-Feruloylserotonin Reduces Inflammation in Human Skin by Neutralizing CCL17 and CCL22 and Inhibiting COX-2 and 5-LOX by Christophe Carola, Andrew Salazar, Christin Rakers, Franck Himbert, Quoc-Tuan Do, Philippe Bernard, Joerg von Hagen

“…Thymus and Activation-Regulated Chemokine (TARC/CCL17) and Macrophage-Derived Chemokine (MDC/CCL22) are two key chemokines exerting their biological effect via binding and activating a common receptor CCR4, expressed at the surface of type 2 helper T (Th2) cells. …”
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Prevalence of immunological aberrations and 22q11.2 deletion in children with conotruncal anomalies: A cross-sectional study by Souvik Das, Arun Kumar Baranwal, Amit Rawat, Ashwini Nair, Sanjeev Hanumantacharya Naganur, Anupriya Kaur, Anand Kumar Mishra, Ankur Jindal, Anit Kaur

“…Given the common embryonic origin of conotruncus and thymus, conotruncal anomalies may be associated with immunological aberrations irrespective of 22q11.2 deletion. …”
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Effects of Essential Oils as Antioxidant and Cryoprotective Agents in Improving Frozen and Thawed Human Sperm Criteria by Hamza Goujet, Ismail Kaarouch, Abderrahim Malki, Modou Mamoune Mbaye, Rosalie Cabry, Noureddine Louanjli, Taha Rhouda, Moncef Benkhalifa

“…This study aimed to assess sperm progressive motility, viability, plasma membrane functionality, and lipid peroxidation levels of human cryopreserved normozoospermic (n = 51) and asthenozoospermic (n = 51) samples without or with the addition of <i>Thymus satureoides</i> (TSEO) (20 µg/mL), <i>Artemisia vulgaris</i> (AVEO) (48 µg/mL), and <i>Rosmarinus officinalis</i> (ROEO) (13 µg/mL) essential oils. …”
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Comparative efficacy of plant derived extracts with the insecticide mospilan on two whitefly species Bemisia tabaci biotype B and Trialeurodes ricini by Hanaa S. Hussein, Mamdouh H. Idriss, Farouk H. El-Gayar, Hebatullah Yehia Saad Mousa, Mohamed Z. M. Salem

“…Abstract The insecticidal, synergistic, and acetylcholinesterase (AChE) inhibitory effects of plant n-hexane extracts (HEs) were evaluated. The HEs from thyme (Thymus vulgaris L.) leaves, garlic (Allium sativum L.) bulbs, and weeping willow (Salix babylonica L.) leaves were used in comparison with the acetamiprid insecticide (mospilan) against two whitefly species, Bemisia tabaci (Gennadius) (Hemiptera: Aleyrodidae) biotype B and Trialeurodes ricini (Genn.) …”
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Endemic Dietary Herb Extracts Reduce Acrylamide and Enhance Sensory Characteristics of Potato Chips by Daniel Assefa, Engida Dessalegn, Kebede Abegaz

“…This study evaluated the impact of soaking potato slices in water containing extracts from three endemic herbs, Lippia adoensis var. adoensis (kesse), Lippia adoensis var. koseret (koseret), and Thymus schimperi Ronninger (tosign), on acrylamide content and sensory attributes of fried potato chips. …”
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RGD-HSA-TAC nanoparticles targeted delivery of tacrolimus and attenuation of podocyte injury in diabetic kidney disease by Zhaochen Guo, Shaohui Gao, Feng Xu, Zige Chen, Qinger Wang, Zhaojie Liu, Ziyue Wang, Weisong Qin, Caihong Zeng, Zhihong Liu, Hao Bao

“…Furthermore, the use of SANPs and CNPs resulted in a decrease in tacrolimus accumulation in the pancreas, lymph nodes, and thymus, thereby reducing the potential to exacerbate hyperglycemia and infection. …”
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