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Egyptian Novel Goose Parvovirus in Immune Organs of Naturally Infected Ducks: Next-Generation Sequencing, Immunohistochemical Signals, and Comparative Analysis of Pathological Chan...
Published 2025-01-01“…Concerning the immune system organs, atrophy in the thymus (60.6%), bursa (45.5%), and spleen (38.3%) was the most common gross lesion. …”
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Synthesis, Characterization, Biological Activity and DNA Binding Studies of Metal Complexes with 4-Aminoantipyrine Schiff Base Ligand
Published 2012-01-01“…Binding of Co(II) complex with calf thymus DNA (CT DNA) was studied by spectral methods.…”
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104
Indications for an antidepressive effect of thymosin alpha-1 in a small open-label proof of concept study in common variable immune deficiency patients with depression
Published 2025-02-01“…Conclusion: This preliminary small study suggests thymus hormone treatment to have antidepressive and related immune correcting effects. …”
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105
A General Mathematical Method for Investigating the Thymic Microenvironment, Thymocyte Development, and Immunopathogenesis
Published 2004-06-01“…Themicroclimate within the thymus, which is shaped by variouscytokines, is first conceptualized into a growth field$\lambda$ and a differentiation field$\mu$, under the influence of which the thymocytesmature. …”
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106
Tumor-Associated Regulatory T Cells in Non-Small-Cell Lung Cancer: Current Advances and Future Perspectives
Published 2022-01-01“…Tumor-associated Tregs display distinct immune signatures in NSCLC compared to thymus-derived Tregs, playing an important role in remodeling the tumor microenvironment (TME). …”
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107
Free Radical Scavenging Capacities and Alleviating Actions of Polysaccharides Extract of Termitomyces le-testui on Methylprednisolone-Induced Immunodepression in Rats
Published 2021-01-01“…Also, it was observed that the extract increased dose-dependent total oxidative stress and thymus index. Finally, the crude polysaccharide-rich extract showed nitrite and hydrogen peroxide scavenging activity in a concentration-dependent manner. …”
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108
Metallothionein-3-mediated intracellular zinc mediates antioxidant and anti-inflammatory responses in the complete Freund’s adjuvant-induced inflammatory pain mouse model
Published 2025-02-01“…The results demonstrated that increasing intracellular Zn2+ levels ameliorate deficits in motor behavior, as well as inflammation in the paw, spleen, and thymus. Furthermore, intracellular Zn2+ was crucial in regulating oxidative stress markers (glutathione, superoxide dismutase, catalase, and malondialdehyde) and inflammatory cytokines, such as tumor necrosis factor-α and interleukin-6, in MT3 knockout mice induced with CFA. …”
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109
DNA Interaction and DNA Cleavage Studies of a New Platinum(II) Complex Containing Aliphatic and Aromatic Dinitrogen Ligands
Published 2011-01-01“…The interaction of this complex with calf thymus DNA (CT-DNA) was investigated by absorption, emission, circular dichroism (CD), and viscosity measurements. …”
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110
Transplantation Tolerance Induced in Humans at the Fetal or the Neonatal Stage
Published 2011-01-01“…Numerous T-cells recognizing the allogeneic, host-type antigens are identified in these patients, but these cells are anergized, following interaction with epithelial cells of the host thymus. Induction of transplantation tolerance at the fetal stage requires minimal engraftment only; in the future it will be possible to further amplify the clinical benefit, using additional cell transplants after birth.…”
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111
The Role of TOX in the Development of Innate Lymphoid Cells
Published 2015-01-01“…TOX is required for the development of CD4+ T lineage cells in the thymus, including natural killer T and T regulatory cells, as well as development of natural killer cells and fetal lymphoid tissue inducer cells, the latter required for lymph node organogenesis. …”
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112
Free-standing microcrystals of a fluorescent organic dye: Preparation and spectroscopic study
Published 2006-01-01“…Suspensions of microcrystals were obtained from an organic fluorescent dye, 4-n-octylamino-7-nitrobenz-2-oxa-1,3-diazole, by reprecipitation in water in the presence of various macromolecules: anionic or cationic PAMAM dendrimer, poly(acrylic acid, sodium salt), poly(acrylamide), and calf thymus DNA. The use of these additives allowed the size and shape of the microcrystals to be controlled. …”
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113
Age-related Changes in p56lck Protein Levels and Phenotypic Distribution of T Lymphocytes in Young Rats
Published 2005-01-01“…The objective of this experiment was to determine changes in the levels of thymic and splenic T-cell p56lck using Western immunoblotting, along with the proportion and number of T-cell subsets in thymus, spleen and blood using flow cytometry in growing Sprague-Dawley rats. …”
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114
DiGeorge Syndrome Presenting as Hypocalcaemia-Induced Seizures in Adulthood
Published 2013-01-01“…The resulting learning difficulties, congenital heart disease, palatal abnormalities, hypoplasia/aplasia of the parathyroid and thymus glands, and immune deficiency generally lead to diagnosis in childhood. …”
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115
Immune Modulation Effect of Administration of Rice Bran Extract with Increased Solubility Fermented by <i>Lentinus edodes</i> UBC-V88 in Cyclophosphamide-Treated Mice Model
Published 2025-01-01“…The FRB and RB groups treated with CY resulted in increased weight of the thymus (1.73 ± 0.40 and 1.45 ± 0.43 mg/g-b.w., respectively) compared to the CY-treated control group (1.05 ± 0.36 mg/g-b.w.). …”
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Seventy-Day Toxicity Study in Juvenile Sprague-Dawley Rats with Semicarbazide (SEM) from Weaning to Sexual Maturity
Published 2022-01-01“…Increased absolute and relative liver and spleen weight in both sexes were observed. Male rats had lower thymus and testes weights, whereas female rats had lower uterine weights. …”
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Regulatory Role of CD4+ T Cells in Myocarditis
Published 2018-01-01“…Due to a defect in clonal deletion of heart-reactive CD4+ T cells in the thymus of mice and humans, significant numbers of heart-specific autoreactive CD4+ T cells circulate in the blood. …”
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Elucidating the Role of the T Cell Receptor Repertoire in Myelodysplastic Neoplasms and Acute Myeloid Leukemia
Published 2025-01-01“…To achieve this, during T cell maturation, the thymus generates a wide repertoire of TCRs. This is essential for understanding cancer evolution, progression, and the efficacy of immunotherapies. …”
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119
Recent Advances in Drug-Induced Hypersensitivity Syndrome/Drug Reaction with Eosinophilia and Systemic Symptoms
Published 2018-01-01“…In this review, we will emphasize that elevations in the levels of several cytokines/chemokines, including tumor necrosis factor- (TNF-) α and the thymus and activation-regulated chemokine (TARC/CCL17), during the early stage of disease, are good markers allowing the early recognition of HHV-6 reactivation. …”
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Carvacrol attenuates N-nitrosodiethylamine induced liver injury in experimental Wistar rats
Published 2015-06-01“…Carvacrol is a main constituent in the essential oils of countless aromatic plants including Origanum Vulgare and Thymus vulgari, which has been assessed for substantial pharmacological properties. …”
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