Ultrasound-assisted enzyme extraction of Dendrobium Officinale polysaccharides: Extraction process, characterization, immunomodulatory effects by Hengpu Zhou, Yingjie Dong, Zhangyun Wu, Xi Peng, Meiqiu Yan, Suhong Chen, Guiyuan Lv

“…It mitigates damage to the thymus and spleen tissues, increases white blood cell counts, regulates the ratio of T lymphocytes and the levels of related factors, enhances macrophage phagocytic function to improve nonspecific immune responses, and boosts the levels of immunoglobulins IgA and IgG to enhance specific immune function. …”
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Protocol for a first-in-human feasibility study of T regulatory cells (TR004) for inflammatory bowel disease using (ex vivo) Treg expansion (TRIBUTE) by Jennifer Clough, Peter Irving, A Toby Prevost, Graham M Lord, Joana Vasconcelos, James B Canavan, Beverley Rodger, D Macallan

“…There is no known cure. In vitro-expanded ‘thymus-derived’ regulatory T cells (tTreg) have shown promise in preclinical models of IBD, leading to interest in their use as a potential therapy in CD. …”
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The Impact of Thyme and Rosemary on Prevention of Osteoporosis in Rats by Amr S. Elbahnasawy, E. R. Valeeva, Eman M. El-Sayed, I. I. Rakhimov

“…The current study was conducted to evaluate the protective effect of thyme (Thymus vulgaris L.) and rosemary (Rosmarinus officinalis L.) against osteoporosis in rats with low calcium intake. …”
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Transcriptional activity of repair, apoptosis and cell cycle genes (TP53, MDM2, ATM, BAX, BCL-2, CDKN1A, OGG1, XPC, PADI4, MAPK8, NF-KB1, STAT3, GATA3) in chronically exposed perso... by V. S. Nikiforov, E. A. Blinova, A. I. Kotikova, A. V. Akleyev

“…The mean accumulated dose to red bone marrow was 426.4±48.2 mGy (1.3–2930.0 mGy), to thymus and peripheral immune organs, 58.9±7.9 mGy (0.1–489.0 mGy). …”
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Cytokines and Water Distribution in Anorexia Nervosa by Hubertus Himmerich, Bethan Dalton, Olivia Patsalos, Ulrike Schmidt, Iain C. Campbell

“…Following blood collection, 27 cytokines and chemokines were quantified using multiplex ELISA-based technology: Eotaxin, Eotaxin-3, granulocyte-macrophage colony-stimulating factor (GM-CSF), interferon- (IFN-) γ, interleukin- (IL-) 1α, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-7, IL-8, IL-10, IL-12/IL-23p40, IL-12p70, IL-13, IL-15, IL-16, IL-17A, interferon γ-induced protein- (IP-) 10, macrophage inflammatory protein- (MIP-) 1α, MIP-1β, monocyte chemoattractant protein- (MCP-) 1, MCP-4, thymus and activation-regulated chemokine (TARC), TNF-α, and TNF-β. …”
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In vitro study reveals antimicrobial activity of essential oils against Klebsiella pneumoniae isolates from Nile tilapia by D. Vaneci-Silva, R. Nakamura-Silva, M. Oliveira-Silva, A. Pitondo-Silva, I. M. Assane, F. Pilarski

“…The primary components of Thymus vulgaris were thymol (53.3%) and p-cymene (20.8%), while those of Melaleuca alternifolia were 1-terpinen-4-ol (40.5%), γ-terpinene (19.7%), and α-terpinene (1.6%). …”
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Towards targeted cancer therapy: Synthesis, characterization, and biological activity of a new Cu(II)-ibuprofen-2,2′-dipyridylamine metal complex by Luís P.G. Monteiro, A. Gomes, C. Silva, Ricardo F. Mendes, Filipe A. Almeida Paz, Dmitry Chernyshov, J. Rocha, F. Martel, T.M. Santos, B.J.M. Leite Ferreira

“…The compound's interaction with the biomolecules bovine serum albumin (BSA) and calf-thymus DNA (CT-DNA), was assessed through UV–Vis, circular dichroism, and fluorescence spectroscopy. …”
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Rapid growing mass of the mandible due to an oral metastasis of thymoma: Case report of an extremely rare localization and review of published cases by Francesco Scilla, Cosimo Rupe, Gioele Gioco, Luca Raffaelli, Filippo Lococo, Ciro Mazzarella, Guido Rindi, Romeo Patini, Carlo Lajolo

“…Thymomas and thymic carcinomas are the two main tumors that can affect the thymus, a lymphatic gland that plays an important role in regulating the immune system. …”
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Comparative Analysis of Five Moroccan Thyme Species: Insights into Chemical Composition, Antioxidant Potential, Anti-Enzymatic Properties, and Insecticidal Effects by Mohamed Ouknin, Hassan Alahyane, Naima Ait Aabd, Sara Elgadi, Youssef Lghazi, Lhou Majidi

“…This study aimed to investigate the chemical composition and bioactivities of essential oils (EOs) from five Moroccan thyme species: <i>Thymus broussonetii</i> subsp. <i>broussonetii, T. maroccanus</i>, <i>T. willdenowii</i>, <i>T. zygis</i> subsp. …”
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Dietary Nigella sativa nanoparticles enhance broiler growth performance, antioxidant capacity, immunity, gene expression modulation, and cecal microbiota during high ambient temper... by Ahmed M. Elbaz, Eman S. Ashmawy, M. A. A. Farahat, Ahmed Abdel‑Maksoud, Shimaa A. Amin, Zangabel S. Mohamed

“…Adding Nano-NS led to an increase in the dressing percentage and the relative weight of the bursa of Fabricius and thymus. Serum high-density lipoprotein levels increased while total cholesterol and low-density lipoprotein concentrations decreased (P < 0.05) in broilers fed Nano-NS compared with control groups. …”
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Reliea® combination of Codonopsis lanceolata and Chaenomeles sinensis extract alleviates airway inflammation on particulate matter 10 plus diesel exhaust particles (PM10D) ‑induced... by Yoon-Young Sung, Won-Kyung Yang, Jong Hoon Kim, Dongseok Shin, Seok June Son, Seung-Hyung Kim

“…RelA decreased the expression of interleukin (IL)-17, chemokine (C-X-C motif) ligand (CXCL)-1, thymus and activation-regulated chemokine, macrophage inflammatory protein-2, IL-1α, TNF-α, mucin 5AC, cyclooxygenase-2, and transient receptor potential cation channel subfamily A or V member 1 in BALF and lung, and inhibited IL-1α and macrophage marker F4/80 localization in lung of PM10D-induced mice. …”
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Scoring System for Lesions Induced by Different Strains of Newcastle Disease Virus in Chicken by Elawad A. Hussein, M. Hair-Bejo, Lawan Adamu, A. R. Omar, Siti S. Arshad, Elmutaz A. Awad, I. Aini

“…In all previous experiments, tissues of brain, trachea, lung, caecal tonsil, liver, kidney, spleen, heart, proventriculus, intestine, and thymus were collected, fixed in 10% buffered formalin, embedded in paraffin, and sectioned. …”
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The active roles of Rhodotorula mucilaginosa ZTHY2 in regulating antioxidant capacity and immune function of Leizhou black ducks by Jiang Wu, Yingxin Hu, Namula Zhao, Wei Yang, Zhibao Chen, Zhibao Chen

“…Moreover, ZTHY2 modulated the mRNA expression profiles of these cytokines in the thymus, spleen, and bursa, thereby sustaining the balance of immune dynamics. …”
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PET Study of Sphingosine-1-phosphate Receptor 1 Expression in Response to S. aureus Infection by Hao Jiang, Jiwei Gu, Haiyang Zhao, Sumit Joshi, Joel S. Perlmutter, Robert J. Gropler, Robyn S. Klein, Tammie L. S. Benzinger, Zhude Tu

“…Ex vivo biodistribution data showed that the uptake of [18F]TZ4877 was increased 30.6%, 54.3%, 74.3%, and 115.3% in the liver, kidney, pancreas, and thymus of the infected mice, respectively, compared to that in normal control mice, indicating that S1PR1 is involved in the early immune response to bacterial infection. …”
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In Vitro Determination of Antimicrobial, Antioxidant and Antiviral Properties of Greek Plant Extracts by Aliki Tsakni, Eirini Kyriakopoulou, Sophia Letsiou, Panagiotis Halvatsiotis, Haralambos Rigopoulos, Niki Vassilaki, Dimitra Houhoula

“…This study examined the in vitro bioactivities of several selected Greek medicinal plants, like <i>Eucalyptus globulus</i> L., <i>Thymus vulgaris</i> L., <i>Salvia rosmarinus</i> L. and <i>Ocimum basilicum</i> L., are well-known for their traditional therapeutic use. …”
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PATHOLOGICAL CHANGES IN MICE TREATED WITH CYCLOPHOSPHAMIDE AND EXOGENOUS DNA by E. V. Dolgova, V. P. Nikolin, N. A. Popova, A. S. Proskurina, K. E. Orishchenko, E. A. Alyamkina, Ya. R. Efremov, S. I. Baiborodin, E. R. Chernykh, A. A. Ostanin, S. S. Bogachev, T. S. Gvozdeva, E. M. Malkova, O. S. Taranov, V. A. Rogachev, A. S. Panov, S. N. Zagrebelnyi, M. A. Shurdov

“…This suggestion is proven by structural equivalents of functional involution of lymphoid organs, such as thymus, spleen, and lymph nodes.We speculate that the death of treated animals resulted from multiple organ dysfunctions caused by accidental involution of lymphoid organs and the systemic inflammatory response syndrome, both associated with injections of fragmented exogenous DNA into experimental animals within the «death window», which corresponds to the final step in the repair of the majority of CP-induced double-strand breaks.…”
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Study on the infection characteristics and pathogenesis of duck circovirus 1 in Cherry Valley meat ducks by Hanqing Li, Guige Xu, Hui Yan, Lei Bei, Mingrui Zhao, Ruihua Zhang, Yu Meng, Yanli Zhu, Liangmeng Wei, Zhijing Xie, Shijin Jiang

“…The virus was initially detected in the liver and the organ with the highest viral titer was the thymus. Besides, immune organ indexes were significantly decreased. …”
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Effect of supplemental dietary phytogenic blends on growth performance, jejunal histomorphometry, and jejunal immunity of broiler chickens by A. Ceylan, P. Saçaklı, Ö. Özgenç Çınar, M. S. Ramay, U. Ahsan, U. Ahsan, J. A. Harijaona, A. G. Bayraktaroğlu, F. Manghebati, A. Calik

“…The control group was fed a basal diet without any additives, and there were two phytogenic supplement groups (blend A, mainly comprising extracts of <i>Thymus</i> <i>vulgaris</i> and <i>Filipendula</i> <i>ulmaria</i>, and blend B, consisting of <i>Ginkgo</i> <i>biloba</i> and <i>Silybum</i> <i>marianum</i>) with two dosage regimens each (100 and 200 mg kg<span class="inline-formula">⁻¹</span> (denoted A<span class="inline-formula">₁₀₀</span> and A<span class="inline-formula">₂₀₀</span>) and 100 and 300 mg kg<span class="inline-formula">⁻¹</span> (B<span class="inline-formula">₁₀₀</span> and B<span class="inline-formula">₃₀₀</span>) of the diet, respectively). …”
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The mechanism of tea tree oil regulating the damage of hydrogen sulfide to spleen and intestine of chicken by Yachao Wang, Yilei Liang, Yan Huang, Wei wang, Xiaoyan Long, Li Jiang, Tingting Cheng, Jinfeng Du, Xuegang Luo

“…Results showed that TTO treatment alleviated tissue damage in the thymus, kidneys, spleen, and bursa of Fabricius, and improved the organ index (P < 0.05) compared with the AVG. …”
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Investigating the Effect of Different Levels of Butyric Acid Glycerides and Clove Oil on Growth Performance, Blood Parameters and Tibia Bone Characteristics of Broiler Chickens by Seyyedeh azam khatami, Mir Daryoush Shakouri, Nemat Hedayat Evrigh

“…The interaction effect of clove oil and butyric acid glycerides did not affect the weight of bursa of fabricius, thymus and spleen of broiler chickens. The amount of calcium, phosphorus and ash of tibia bone was significantly affected by butyric acid glycerides. …”
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