Emulation of ARISTOTLE and ROCKET AF trials in real-world atrial fibrillation patients results in similar efficacy and safety as original landmark trials: insights from the GARFIEL... by Ralf E Harskamp, Karen Pieper, A John Camm, Ajay K Kakkar, Jelle C L Himmelreich, Saverio Virdone, Jean-Pierre Bassand, Frank Misselwitz, Freek W A Verheugt, Frank Cools, Harry Gibbs, Antônio C Pereira-Barretto

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Gastrointestinal Bleeding due to Pancreatic Disease-Related Portal Hypertension by Kexin Zheng, Xiaozhong Guo, Ji Feng, Zhaohui Bai, Xiaodong Shao, Fangfang Yi, Yongguo Zhang, Rui Zhang, Han Liu, Fernando Gomes Romeiro, Xingshun Qi

“…Left-sided portal hypertension (LSPH) is a rare type of portal hypertension, which occurs due to obstruction, stenosis, or thrombosis within the splenic vein. Pancreatic diseases are the most common etiology of LSPH. …”
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Efficacy and Safety of Dual Antiplatelet Therapy in Patients Undergoing Coronary Stent Implantation: A Systematic Review and Network Meta-Analysis by Yi Xu, Yimin Shen, Delong Chen, Pengfei Zhao, Jun Jiang

“…Primary endpoints were all-cause mortality, cardiac death, myocardial infarction (MI), major bleeding, any bleeding, definite or probable stent thrombosis (ST), and net adverse clinical events (NACE). …”
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Effect of humanistic care combined with risk management nursing model on the incidence of venous thromboembolism in critically ill patients with cancer (人文关怀联合风险管理干预重症肿瘤患者静脉血栓栓塞症的效... by ZHEN Yuhong (郑玉红), PEI Xiaolu (裴晓璐)

“…Conclusion In the nursing management of critically ill patients with cancer, the humanistic care combined with risk management nursing model applied is conducive to reduce the incidence of deep venous thrombosis and improve patient satisfaction. (目的 探讨人文关怀联合风险管理护理模式对重症肿瘤患者静脉血栓栓塞症发生率的影响。…”
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Comparative analysis between abdominal aortic aneurysm and popliteal artery aneurysm by Marcos Vinícius Melo de Oliveira, MD, PhD, Alexandre Malta Brandão, MD, PhD, Gina Camillo Rocha Silvestre, BS, Alexandre Queiroz Silva, BS, Michele Alberto Marques, BS, Marcia Martins Reis, PhD, Maria de Lourdes Higuchi, MD, PhD, Erasmo Simão da Silva, MD, PhD

“…Clinical Relevance: The clinical significance of this study lies in its potential to enhance our understanding of the distinct pathophysiological mechanisms underlying abdominal aortic aneurysms, which is often associated with rupture, and popliteal artery aneurysms, which are more prone to thrombosis and distal embolization. By comprehensively comparing the biomechanical, histological, and immunohistochemical aspects of these two aneurysm types, the study aims to illuminate the factors contributing to their differing clinical presentations and outcomes.…”
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Pathomorphological changes of the placenta in coronavirus disease (COVID-19) in pregnant women in the second and third trimesters of pregnancy by T.V. Savchuk

“…In the acute phase of the disease, placentas predominantly showed congestion, thrombosis, hemorrhages, and placentitis – 100% (95% CI: 94.5%-100%). …”
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Comparing efficacy and safety of low-dose versus standard-dose antiplatelet therapy in stroke patients: a meta-analysis by Zhao Ren, Chunxing Li, Xin Zhang, Lichaoyue Sun, Hui Zhu, Dongxiao Wang, Yumin Wang, Shuo Liang, Guanchun Wang

“…This requires careful dosage adjustments to balance thrombosis and bleeding risks.ObjectiveThis study compared the efficacy and safety of low-dose versus standard-dose antiplatelet therapy in stroke patients.MethodsWe conducted a comprehensive search across multiple databases, including PubMed, Embase, the Cochrane Library, ClinicalTrials.gov, CNKI, and the Wanfang Medical Database, up to March 2024. …”
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Comparison of First- and Second-Generation Drug-Eluting Stents in Patients with Acute Myocardial Infarction and Prediabetes Based on the Hemoglobin A1c Level by Yong Hoon Kim, Ae-Young Her, Myung Ho Jeong, Byeong-Keuk Kim, Sung-Jin Hong, Seunghwan Kim, Chul-Min Ahn, Jung-Sun Kim, Young-Guk Ko, Donghoon Choi, Myeong-Ki Hong, Yangsoo Jang

“…The secondary outcome was probable or definite stent thrombosis (ST). Results. After propensity score-matching (PSM) analysis, two PSM groups (698 pairs, n = 1396, C-statistics = 0.725) were generated. …”
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Patent Ductus Arteriosus Stenting via Percutaneous Common Carotid Artery Access for Ductus Dependent Pulmonary Blood Flow in Newborns and Infants: Experience in Latvia by Zanda Grīnberga, Elizabete Zaharāne, Pauls Sīlis, Valts Ozoliņš, Normunds Sikora, Elīna Ligere

“…Patients in need of PDA stenting are newborns or small infants and recent data suggests that a weight of <4 kg increases the risk of thrombosis from femoral arterial catheterisation. Carotid access for newborn cardiac catheterisation avoids femoral arterial injury and improves the catheter course for certain transvasal procedures. …”
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Reduction of Lipid-Core Burden Index in Nonculprit Lesions at Follow-Up after ST-Elevation Myocardial Infarction: A Randomized Study of Bioresorbable Vascular Scaffold versus Optim... by Joelle Kefer, Patrick Chenu, Olivier Gurné, Frederic Maes, Théophile Tamakloé, Christophe Beauloye

“…Overall survival was 100%, target lesion failure was 13%, and stent thrombosis was 0%. Conclusions. BVS + OMT and OMT appear as similarly safe and effective in reducing maxLCBI4mm in NC-LRPs at 2-year follow-up after STEMI.…”
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Comparison of biodegradable and durable polymer drug-eluting stents in acute coronary syndrome: a meta-analysis by Tingting Wei, Can Huang, Yifan Zeng, Haoyong Yuan, Zhongshi Wu, Ting Lu, Yalin Liu

“…Safety endpoints included all-cause death, cardiac death, target vessel myocardial infarction and stent thrombosis (ST).Methods We searched PubMed, Medline, Embase and the Cochrane Controlled Register of Trials for comparative studies of BP-DES and DP-DES in patients with ACS from January 2000 to July 2021. …”
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Nursing of recurrent malposition of peripherally inserted central catheters in a patient with thoracic outlet syndrome and related nursing measures (1例胸廓出口综合征患者经外周静脉置入中心静脉导管置管反复原发性... by ZHANG Liuyan (张柳燕), HUANG Guohua (黄果花), LI Xiufeng (李秋凤)

“…There were no complication such as thrombosis and infection after the catheter placement, and the patient successfully completed autologous stem cell transplantation and was discharged from the hospital. …”
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Clinical Recommendations of the Northwest Society for Enteral and Parenteral Nutrition, Interregional Association for Emergency Surgery, Russian Gastroenterological Association, Un... by Yu. V. Averyanova, E. M. Batyrshin, A. E. Demko, G. E. Ivanova, V. T. Ivashkin, L. N. Kostyuchenko, A. V. Lapitsky, I. N. Leiderman, V. M. Luft, I. V. Maev, I. G. Nikitin, M. S. Novruzbekov, Е. A. Poluektova, A. L. Potapov, A. V. Sytov, A. S. Trukhmanov

“…The main referral indications for small bowel transplantation (SBT) are: fast-progressing cholestatic liver disease-complicated irreversible intestinal failure; thrombosis of two or more central venous conduits used for parenteral nutrition; recurrent catheter-associated bloodstream infection.Conclusion. …”
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PICC catheterization and maintenance for severely and critically ill patients with COVID-19 in the isolation ward (隔离病房重型和危重型新型冠状病毒肺炎患者PICC置管管理)... by HAN Huishan (韩会山), LI Naxin (李纳新), LYU Yuan (吕源), LI Yuhua (李玉华), LI Yali (柳雅立)

“…There was no postoperative complications such as infection, bleeding, phlebitis, thrombosis, and no nosocomial infection occurred. The implementation of PICC catheterization in severely and critically ill patients in the isolation ward is safe and effective, and standardized protection in catheterization can effectively reduce the risk of cross-infection in hospital. …”
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Impact in Clinical Practice of the European Medicines Agency Health Alert About the Restriction of the Use of JAK Inhibitors by Elisabet Castañeda-Estévez, Cristina Vergara-Dangond, Martina Steiner, Maria Beatriz Paredes-Romero, Ana Esteban-Vázquez, Tatiana Cobo-Ibañez, Laura Trives-Folguera, Maria Liz Romero-Bogado, Isabel De La Cámara-Fernández, Patricia Richi-Alberti, Ana Acosta-Alfaro, Iría De la Osa-Subtil, Santiago Muñoz-Fernández

“…The most frequent adverse events were infections (5.9%) and neoplasms (2.9%). Deep vein thrombosis and haemorrhagic stroke each occurred in 1% of patients, with no cases of ischemic stroke or ischemic heart disease. …”
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Effect of humanistic care combined with risk management nursing model on the incidence of venous thromboembolism in critically ill patients with cancer (人文关怀联合风险管理干预重症肿瘤患者静脉血栓栓塞症的效... by ZHEN Yuhong (郑玉红), PEI Xiaolu (裴晓璐)

“…Conclusion In the nursing management of critically ill patients with cancer, the humanistic care combined with risk management nursing model applied is conducive to reduce the incidence of deep venous thrombosis and improve patient satisfaction. (目的 探讨人文关怀联合风险管理护理模式对重症肿瘤患者静脉血栓栓塞症发生率的影响。…”
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Structural tailoring of etoricoxib: A spectrochemical, medicinal and pharmacological study by Bakul Akter, Silvia Aishee, Abdullah Hridoy, Md. Mehedi Hasan Pulok, Mohammad Ariful Islam, Antu Biswas, Aurna Patwary, Majedul Hoque, MD. Sazidul Islam, Md. Nipatul Hasan Nirob, Faisal Islam Chowdhury, Monir Uzzaman

“…Nevertheless, its therapeutic efficacy is limited by poor aqueous solubility, low bioavailability, and significant cardiovascular risks, including increased blood pressure, thrombosis, and the potential for myocardial infarction. …”
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Surgical Outcomes and Sociodemographic Disparities Across All Races: An ACS-NSQIP and NHIS Multi-Institutional Analysis of Over 7.5 Million Patients by Dany Y. Matar, BA, Samuel Knoedler, Anthony Y. Matar, BS, Sarah Friedrich, PhD, Harriet Kiwanuka, MD, Ryoko Hamaguchi, MD, Carla M. Hamwi, BS, Gabriel Hundeshagen, MD, MMS, Valentin Haug, MD, Ulrich Kneser, MD, PhD, Keisha Ray, PhD, Dennis P. Orgill, MD, PhD, Adriana C. Panayi, MD, PhD

“…AS and B/AA patients are more prone to transfusions, with B/AA patients showing elevated rates of pulmonary embolism, deep vein thrombosis, renal failure, and insufficiency. Disparities in discharge destinations exist. …”
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Percutaneous Coronary Intervention Complexity and Risk of Adverse Events in relation to High Bleeding Risk among Patients Receiving Drug-Eluting Stents: Insights from a Large Singl... by Hao-Yu Wang, Yang Wang, Dong Yin, Run-Lin Gao, Yue-Jin Yang, Bo Xu, Ke-Fei Dou

“…The primary ischemic endpoint was major adverse cardiovascular events (MACE) (composite of cardiac death, myocardial infarction, definite/probable stent thrombosis, and target lesion revascularization), and primary bleeding endpoint was Bleeding Academic Research Consortium (BARC) type 2, 3, or 5 bleeding. …”
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The effect of pharmaceutical composition based on L-carnitine on structural and functional features of rat placenta in the model of passive tobacco smoking by I.V. Volokhov, V.A. Rybak, L.Yu. Sergienko, S.S. Sokolova, S.P. Kustova

“…The gravidoprotective effect in rats treated with a pharmaceutical composition based on L-carnitine and exposed to passive smoking was manifested by a significant decrease in the severity of negative changes in the placental histological structure, which were recorded in animals from the passive smoking group, as evidenced by the following signs of increased width of the labyrinthine section normal width of the decidual membrane, no expansion of blood-filled lacunae, sufficient contact area of fetal and maternal vessels, no signs of thrombosis in maternal lacunae, the predominant number of fetal capillaries without signs of hemostasis with normal blood filling and wall thickness. …”
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