Challenges and considerations of genetic testing in von Willebrand disease by Omid Seidizadeh, Luciano Baronciani, Flora Peyvandi

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Recombinant factor VIIa: new insights into the mechanism of action through product innovation by Miguel A. Escobar, Maureane Hoffman, Giancarlo Castaman, Cedric Hermans, Johnny Mahlangu, Johannes Oldenburg, Charles L. Percy, Mark T. Reding, Amy D. Shapiro, Steven W. Pipe

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Chronic endothelial inflammation in PWH leads to reduced circulating megakaryocyte progenitor cells by Tong Li, Colleen Hadigan, Jaeil Ahn, Chinmayee Mehta, Makheni Jean Pierre, Danial Mahmood, Metin Ozdemirli, Cooper James, Princy Kumar, Marta Catalfamo

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Tenecteplase vs Reteplase in Patients with Acute ST-Elevation Myocardial Infarction: A Retrospective Cohort Study by Adham Mohamed PharmD, Sara Mahmoud PharmD, Amr M. Fahmi PhD, Ahmed Mahfouz MSc, Tayseer Kanaan MD, Jihad Jaber MD, Mansour Alkhawi MD, Saleh Alkhalaf MD, Hassan Kodimi MD, Ahmed Shaaban MD, Omar Alshibli MD, Awad Almasalmeh MD, Salaheddin Arafa MD, Salah Elbdri MD, Suhail Falah MD, Fayez Altrad MD, Ezeldin Soaly MD, Rasha Elenany PharmD, Sumaya Alyafei PharmD, Abdul Rahman Arabi MD

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Clinical management of bleeding manifestations in a family with the thrombomodulin C1611>A (p.Cys537Stop) mutation by Serge Pierre-Louis, Johalene Rabout, Octavio Labrada, Fatima Radouani, Emeline Chonville, Beatrice Ferrey, Olivier Pierre-Louis, Yesim Dargaud

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The detrimental impact of ferritin “normal” ranges on diagnosis of bleeding disorders in women by Michelle Sholzberg, Grace H. Tang

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Transcription factor RUNX1 regulates coagulation factor XIII-A (F13A1): decreased platelet-megakaryocyte F13A1 expression and clot contraction in RUNX1 haplodeficiency by Fabiola Del Carpio-Cano, Natthapol Songdej, Liying Guan, Guangfen Mao, Lawrence E. Goldfinger, Jeremy G.T. Wurtzel, Kiwon Lee, Michele P. Lambert, Mortimer Poncz, A. Koneti Rao

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Structural bioinformatics for rational drug design by Soroush Mozaffari, Agnethe Moen, Che Yee Ng, Gerry A.F. Nicolaes, Kanin Wichapong

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Association of high γ′ fibrinogen levels with adverse events in patients with COVID-19 by Queen Revollido, Lydia Buzzard, David X. Lee, Matthew Strnad, Scott McLoud, Akram Khan, William B. Messer, David H. Farrell

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Characterization of the procoagulant phenotype of amniotic fluid across gestation in rhesus macaques and humans by Chih Jen Yang, Lyndsey E. Shorey-Kendrick, Cristina Puy, Ashley E. Benson, Phillip A. Wilmarth, Ashok P. Reddy, Keith D. Zientek, Kilsun Kim, Adam Crosland, Chaevien S. Clendinen, Lisa M. Bramer, Olivia L. Hagen, Helen H. Vu, Joseph E. Aslan, Owen J.T. McCarty, Joseph J. Shatzel, Brian P. Scottoline, Jamie O. Lo

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Screening for gene variants causing inherited platelet disorders: are the cons always cons? by Loredana Bury, Emanuela Falcinelli, Anna Maria Mezzasoma, Giulia Ciarrocca Taranta, Elisa Giglio, Caterina Matteucci, Roberta La Starza, Alessandra Carotti, Paolo Gresele

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Altered clot structure in pregnant women who will develop postpartum hemorrhage by Claire de Moreuil, Brigitte Pan-Petesch, François Anouilh, Dino Mehic, Theresa Schramm, Christoph Friedl, Alisa S. Wolberg, Francis Couturaud, Johanna Gebhart, Cihan Ay, Ingrid Pabinger

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Venous thromboembolism still leads on maternal death by Amelia Shard, Catherine Prodger, Sue Pavord

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Comparative analyses of the hemostatic efficacy and surgical device performance of powdered oxidized regenerated cellulose and starch-based powder formulations by Marianne Stark, Allen Y. Wang, Brittny Corrigan, Henok G. Woldu, Samar Azizighannad, Gustavo Cipolla, Richard Kocharian, Hector De Leon

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Prophylactic use of recombinant ADAMTS-13 during pregnancy for congenital thrombotic thrombocytopenic purpura by Éloïse Colliou, Agnès Ribes, Clotilde Gaible, Mathilde Marlas, David Ribes, Isabelle Labadens, Paul Guerby, Stanislas Faguer

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Altered shear stress of blood flow causes plasma membrane damage in endothelial cells by Nikita Raj, Chang Pan, Ann Marleen Starke, Anna L. L. Matos, Oliver Soehnlein, Volker Gerke

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Graft-Versus-Host Disease Sustains Coagulation Activity for two Years After Pediatric Allogeneic Hematopoietic Stem Cell Transplantation by Satu Långström MD, PhD, Minna Koskenvuo MD, PhD, Pasi Huttunen MD, PhD, Riitta Lassila MD, PhD, Mervi Taskinen MD, PhD, Susanna Ranta MD, PhD, Markku Heikinheimo MD, PhD, Anne Mäkipernaa MD, PhD

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Impact of antiplatelet therapy on hemostatic plug formation in the setting of thrombocytopenia by Robert H. Lee, Abigail Ballard-Kordeliski, Summer R. Jones, Wolfgang Bergmeier

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Evaluation of Rivaroxaban Exposure via Anti-Xa Levels During VTE Prophylaxis in Hospitalized Patients by Kaitlin Blotske PharmD, Toral Patel PharmD, BCPS, Toby Trujillo PharmD, FCCP, FAHA, BCPS, Matthew Marlar MLS (ASCP), Stuart Lind MD, Henry Kramer MD, Kathryn Hassell MD, Tyree H. Kiser PharmD, FCCM, FCCP, BCCCP, BCPS

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Adeno-associated virus-based gene therapy for hemophilia–addressing the gaps by Wolfgang Miesbach, Paul Batty, Pratima Chowdary, Sylvia Fong, Radoslaw Kaczmarek, Frank W.G. Leebeek, Brian Long, Johnny Mahlangu, Mike Makris, Glenn F. Pierce, Steven W. Pipe, Alok Srivastava, Jan Voorberg, Flora Peyvandi

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