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19641
The Case for Musical Instrument Training in Cerebral Palsy for Neurorehabilitation
Published 2016-01-01“…These multiple demands during instrument playing, together with the entertaining character of music, have led to the development and investigation of music-supported therapies, especially for rehabilitation with motor disorders resulting from brain damage. …”
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19642
Interferon-based agents for current and future viral respiratory infections: A scoping literature review of human studies.
Published 2022-01-01“…Studies demonstrated mixed efficacy but generally positive safety and tolerability. Host-directed therapies, such as IFN or IFN inducers, are worthy of additional research to target viral respiratory infections lacking direct-acting antivirals.…”
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19643
Injectable iodine-containing peptide hydrogel for treatment of MRSA infection
Published 2025-05-01“…Our findings highlight the potential of this innovative hydrogel system for stable iodine application under humid and aqueous physiological conditions, offering a promising platform for future antibacterial therapies in clinical settings.…”
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19644
Ignoring Gender-Based Immunometabolic Reprograming, a Risky Business in Immune-Based Precision Medicine
Published 2025-01-01“…On the other hand, reproductive-age females also show a more potent immune response against infections and vaccines than their age-matched males—furthermore, some immune-based therapies, including immune checkpoint inhibitors (ICIs), show gender-based efficacy and adverse events. …”
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19645
Trophic Factors from Tissue Stem Cells for Renal Regeneration
Published 2015-01-01“…Stem cell therapies against renal injury have been advancing. …”
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19646
The role of metagenomic next-generation sequencing in diagnosing and managing post-kidney transplantation infections
Published 2025-01-01“…Additionally, we consider the future prospects of mNGS in overcoming current diagnostic limitations and its potential for guiding targeted therapies, particularly in detecting antimicrobial resistance and emerging pathogens. …”
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19647
The Role of TGFβ Signaling in Squamous Cell Cancer: Lessons from Mouse Models
Published 2012-01-01“…A better understanding of the mechanisms underlying the duality of TGFβ1 action in carcinogenesis will inform potential use of this signaling pathway for targeted therapies.…”
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19648
Liposomal Antioxidants for Protection against Oxidant-Induced Damage
Published 2011-01-01“…Antioxidants have yet to be rendered into reliable and safe therapies because of their poor solubility, inability to cross membrane barriers, extensive first-pass metabolism, and rapid clearance from cells. …”
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19649
Disulfidptosis as a key regulator of glioblastoma progression and immune cell impairment
Published 2025-01-01“…SMC4 inhibition reduced LN299 cell migration and increased chemotherapy sensitivity, decreasing CD4 and CD8 T cell activation.ConclusionsDisulfidptosis-Tex genes are pivotal in glioblastoma progression and immune interactions, offering new avenues for improving anti-glioblastoma therapies through modulation of T cell exhaustion.…”
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19650
Cellular MR Imaging
Published 2005-07-01“…New applications of cellular MR imaging will be directed, for instance, towards our understanding of hematopoietic (immune) cell trafficking and of novel guided (stem) cell-based therapies aimed to be translated to the clinic in the future.…”
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19651
Linezolid and serotonin syndrome
Published 2025-02-01“…Exploring pharmacogenomic approaches and alternative therapies with lower serotonin syndrome risks is recommended to enhance patient outcomes while maintaining linezolid’s efficacy in treating severe bacterial infections.…”
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19652
Recent advances in polymeric nanoparticles for the treatment of hepatic diseases
Published 2025-01-01“…Compared to traditional therapies, they offer significant advantages in the treatment of liver disease by improving outcomes and reducing side effects. …”
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19653
Skin Matters: Identifying Pain Mechanisms and Predicting Treatment Outcomes
Published 2013-01-01“…There is potential for these findings to predict treatment outcomes in clinical practice and to develop new therapies for different pain conditions. These findings should enhance the physician's ability to evaluate and treat diverse types of pain.…”
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19654
Love Addiction - Current Diagnostic and Therapeutic Paradigms in Clinical Psychology.
Published 2023-04-01“… # Conclusions Group psychotherapy has proved to be a valid alternative, in fact the scientific landscape suggests that most group therapies are successful because these dynamics involve the reward and attachment systems in the brain in most subjects. …”
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19655
Surgical modalities in the treatment of vitiligo
Published 2024-12-01“…Vitiligo presents a challenge not only in its medical management but also in its impact on patients’ psychosocial well-being. While medical therapies can halt disease progression, achieving repigmentation, especially in challenging areas, remains a hurdle. …”
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19656
Extracellular vesicles—a new player in the development of urinary bladder cancer
Published 2025-01-01“…An in-depth understanding of the role EVs play in the development of urinary bladder cancer is crucial for the development of future anticancer therapies.…”
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19657
Harnessing nanotechnology for enhanced epilepsy management
Published 2024-12-01“…Prospects include nanodroplet drug delivery, neural repair with nanomaterials, and highly individualized epilepsy therapies. These innovations could significantly improve traditional treatments, patient outcomes, and quality of life, underscoring the importance of collaboration among healthcare providers, scientists, and technologists to maximize their potential. …”
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19658
Muscle-Specific Tyrosine Kinase-Associated Myasthenia Gravis: A Neuromuscular Surprise
Published 2021-01-01“…It responds inconsistently to steroids, but plasma exchange and immunosuppressive therapies have shown promising results. We report a case of a 49-year-old female who presented with acute hypoxic respiratory failure. …”
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19659
Pan-inhibition of super-enhancer-driven oncogenic transcription by next-generation synthetic ecteinascidins yields potent anti-cancer activity
Published 2025-01-01“…Consequently, these compounds exhibit cytotoxic activity across distinct subpopulations of metastatic melanoma cells and inhibit tumor proliferation, including those resistant to current therapies. These findings extend to other cancers, like small cell lung cancer, recently approved for ecteinascidin-based treatment. …”
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19660
Association between HMGB1 and COPD: A Systematic Review
Published 2015-01-01“…Current anti-inflammatory therapies are poorly effective in maintaining lung function and symptoms of COPD. …”
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