Genome Editing as a Vehicle to Drive Successful Chimeric Antigen Receptor T Cell Therapies to the Clinic by Caitlin R Hopkins, Joseph A Fraietta

“… Chimeric antigen receptor (CAR) T cells have emerged as an effective therapy for patients with relapsed and refractory haematological malignancies. …”
Get full text

Identifying Occupational Therapy Research Priorities in Trinidad and Tobago: A Group Concept Mapping Study by Savannah Murray-Mendes, Anastasia Raquel Martinez, Katie L. Hackett

“…Occupational Therapy International…”
Get full text

Should My Patient with Inflammatory Bowel Disease on Immunosuppressive Therapy be Vaccinated against Influenza Virus? by Neeraj Narula, Deborah LR Yamamura, John K Marshall

“…The present article reviews the literature regarding the safety and efficacy of influenza vaccination in IBD patients receiving immunosuppressive therapy.…”
Get full text

Identifying Risk Factors Associated with Inappropriate Use of Acid Suppressive Therapy at a Community Hospital by Amandeep Singh, Vijay Bodukam, Kirit Saigal, Jaya Bahl, Yvette Wang, Alexandra Hanlon, Yinghui Lu, Michael Davis

“…By examining the prescribing patterns and inappropriate use of acid suppressive therapy (AST) during hospitalization and at discharge we sought to identify the risk factors associated with such practices. …”
Get full text

Approaches for difficult-to-induce-seizures electroconvulsive therapy cases (DEC): a Japanese expert consensus by Yoshiteru Takekita, Taro Suwa, Kazuyuki Yasuda, Hirotsugu Kawashima, Wataru Omori, Naoki Kurimoto, Takashi Tsuboi, Takamasa Noda, Nobuatsu Aoki, Ken Wada, Ken Inada, Minoru Takebayash, Expert Consensus Development Working Group, Electroconvulsive Therapy Committee, Japanese Society of General Hospital Psychiatry

Subjects: “…Electroconvulsive therapy…”
Get full text

LBP-CD155 Liposome Nanovaccine Efficiently Resist Colorectal Cancer and Enhance ICB Therapy by Yan Y, Duan T, Xue X, Yang X, Liu M, Ma B, Duan X, Su C

“…Prophylactic and therapeutic combination regimens with anti-PD-1 treatment demonstrate synergism that stimulates T-cell infiltration into tumors and counteracts immunosuppression, leading to remarkable tumor remission and enhancing the efficacy of immune checkpoint therapy in solid tumors.Conclusion: Our work provided that LBP-CD155L NVs may serve as a promising tool for reversing tumor immunosuppressive microenvironment and enhancing ICB therapy in CRC.Keywords: Lycium barbarum polysaccharides, nanovaccines, nanovaccine codelivery, CD155, tumor immunotherapy…”
Get full text

Advancements in Research on Non-AR- Signaling Pathways and Targeted Therapies for Castration-Resistant Prostate Cancer by Haq Dad, Asger Hansen

Get full text

Changes in clinical and imaging variables during withdrawal of heart failure therapy in recovered dilated cardiomyopathy by Brian P. Halliday, Ruth Owen, John Gregson, Ali Vazir, Rebecca Wassall, Zohya Khalique, Amrit S. Lota, Upasana Tayal, Daniel J. Hammersley, Richard E. Jones, Dudley J. Pennell, Martin R. Cowie, John G.F. Cleland, Sanjay K. Prasad

“…Abstract Aims This study aimed to profile the changes in non‐invasive clinical, biochemical, and imaging markers during withdrawal of therapy in patients with recovered dilated cardiomyopathy, providing insights into the pathophysiology of relapse. …”
Get full text

Occupational therapy in overweight and obesity care: Australian perspectives from a mixed methods study by Kieva Richards, Olivia Beattie, Danielle Hitch, Genevieve Pepin

Subjects: Get full text

Antithrombotic therapy for a case report of acute myocardial infarction after laparoscopic radical cystectomy by Zilong Wang, Zilong Wang, Zilong Wang, Zilong Wang, Huisheng Yuan, Junhao Chu, Shishuai Duan, Zhihui Zhang, Changze Song, Muwen Wang

Subjects: “…antithrombotic therapy…”
Get full text

Individual-network based predictions of microbial interaction signatures for response to biological therapies in IBD patients by Federico Melograna, Padhmanand Sudhakar, Behnam Yousefi, Behnam Yousefi, Clara Caenepeel, Gwen Falony, Gwen Falony, Gwen Falony, Sara Vieira-Silva, Sara Vieira-Silva, Sara Vieira-Silva, Sreenikhitha Krishnamoorthy, David Fardo, Bram Verstockt, Bram Verstockt, Jeroen Raes, Jeroen Raes, Severine Vermeire, Severine Vermeire, Kristel Van Steen

Subjects: Get full text

Defects of CTLA-4 Are Associated with Regulatory T Cells in Myasthenia Gravis Implicated by Intravenous Immunoglobulin Therapy by Wenhua Xu, Mingshan Ren, Swagata Ghosh, Kai Qian, Zhaofeng Luo, Aimei Zhang, Cuiping Zhang, Jiajun Cui

“…Overall, our study may suggest a role of CTLA-4 in functionally defected Treg cells in MG and its actions involved in IVIg therapy.…”
Get full text

The usability of a virtual reality augmented training program to teach goniometry to occupational therapy students by Nancy A. Baker, Jane O’Shanassy, Carolyn A. Unsworth

“…The aim of this proof-of-concept study was to develop and examine the usability and establish preliminary efficacy of an Embodied Goniometric Occupational Therapy Training Program (EGOTTP) to teach occupational therapy students wrist goniometry. …”
Get full text

Multifocal Aggressive Squamous Cell Carcinomas Induced by Prolonged Voriconazole Therapy: A Case Report by C. Morice, A. Acher, N. Soufir, M. Michel, F. Comoz, D. Leroy, L. Verneuil

“…Prolonged voriconazole therapy may induce skin reactions, with 1% of severe photosensitivity accidents. …”
Get full text

Percutaneous coronary intervention vs. medical therapy in patients on dialysis with coronary artery disease in China by Enmin Xie, Yaxin Wu, Zixiang Ye, Yong He, Hesong Zeng, Jianfang Luo, Mulei Chen, Wenyue Pang, Yanmin Xu, Chuanyu Gao, Xiaogang Guo, Lin Cai, Qingwei Ji, Yining Yang, Di Wu, Yiqiang Yuan, Jing Wan, Yuliang Ma, Jun Zhang, Zhimin Du, Qing Yang, Jinsong Cheng, Chunhua Ding, Xiang Ma, Chunlin Yin, Zeyuan Fan, Qiang Tang, Yue Li, Lihua Sun, Chengzhi Lu, Jufang Chi, Zhuhua Yao, Yanxiang Gao, Changan Yu, Jingyi Ren, Jingang Zheng, Rongman Jia

“…This study aimed to evaluate the association between PCI and clinical outcomes as compared with medical therapy alone in patients undergoing dialysis with CAD in China. …”
Get full text

Menopausal Hormone Therapy: Its Role in the Prevention of Cardiovascular Diseases and the Risk of Breast Cancer in Women by Tam Thai Thanh Tran, Thu Minh Phung, Anh Thi Mai Do, Quynh Tran Mai Ly, Tin Hoang Nguyen

“…Objective: This review was conducted to explain how menopausal hormone therapy (MHT) benefits cardiovascular diseases (CVDs) and how to control the risk of breast cancer. …”
Get full text

Onset of Celiac Disease after Treatment of Chronic Hepatitis C with Interferon Based Triple Therapy by Amandeep Singh, Nayere Zaeri, Immanuel K. Ho

“…Patients treated with interferon (IFN) based therapies may develop exacerbation of autoimmune disease. …”
Get full text

Metastatic melanoma: An integrated analysis to identify critical regulators associated with prognosis, pathogenesis and targeted therapies by Zeinab Chaharlashkar, Yousof Saeedi Honar, Meghdad Abdollahpour-Alitappeh, Sepideh Parvizpour, Abolfazl Barzegar, Effat Alizadeh

Get full text

Meta-Analysis of Daoyin Therapy on Therapeutic Effect and Quality of Life in Patients with Stable Angina Pectoris by QIAO Meng, WANG Zhifei, TAN Chaoren, DAI Jingang

Subjects: Get full text

Acupuncture combined with multiple therapies for angina pectoris: a systematic review and network meta-analysis by Xiangyu Kong, You Gu, Zhao Qiu

Subjects: Get full text