Molecular Network Associated with MITF in Skin Melanoma Development and Progression by Ichiro Yajima, Mayuko Y. Kumasaka, Nguyen Dinh Thang, Yuji Goto, Kozue Takeda, Machiko Iida, Nobutaka Ohgami, Haruka Tamura, Osamu Yamanoshita, Yoshiyuki Kawamoto, Keiko Furukawa, Masashi Kato

“…To find better approaches to molecular-based therapies for patients, understanding MITF function in skin melanoma development and progression is important. …”
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GC-MS analysis of cholesterol lowering dietary supplements by Velislava Todorova, Diana Karcheva-Bahchevanska, Stanislava Ivanova

“…In recent decades, dietary supplements (DSs) have gained attention as potential additions to conventional cholesterol management therapies, but their efficacy and safety are questionable. …”
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Stem Cell Tracking with Nanoparticles for Regenerative Medicine Purposes: An Overview by Lisa Accomasso, Clara Gallina, Valentina Turinetto, Claudia Giachino

“…Accurate and noninvasive stem cell tracking is one of the most important needs in regenerative medicine to determine both stem cell destinations and final differentiation fates, thus allowing a more detailed picture of the mechanisms involved in these therapies. Given the great importance and advances in the field of nanotechnology for stem cell imaging, currently, several nanoparticles have become standardized products and have been undergoing fast commercialization. …”
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From Plant to Patient: A Historical Perspective and Review of Selected Medicinal Plants in Dermatology by Aygun Israyilova, Tsvetomira Zhivkova Peykova, Ben Kittleson, Paul Caleb Sprowl, Taha Osman Mohammed, Cassandra L. Quave

“…Today, with increasing patient preference for natural therapies, modern medicine is now more than ever incorporating age-old knowledge of herbal remedies useful in treating skin conditions into modern-day treatments. …”
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From Infection to Tumor: Exploring the Therapeutic Potential of Ciprofloxacin Derivatives as Anticancer Agents by Hesham M. Hassan, Roket Hassan, Ranya Mohammed Elmagzoub, Ahmed Al-Emam, Konstantinos Kossenas, Ahmed S. Abdel-Samea, Hazim O. Khalifa, Suleyman Akocak, Stefan Bräse, Hamada Hashem

“…Additionally, it outlines their future directions, such as enhancing their efficacy, selectivity, and investigating potential synergy with other chemotherapeutic agents, offering a promising avenue for developing new therapies for cancer.…”
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Risk Stratification and Adjuvant Chemotherapy for High‐Risk Stage IA Lung Adenocarcinoma: The Unmet Needs by Chen Shen, Haoran Liu, Bofei Li, Jiaming Wang, Yiyang Wang, Feichao Bao, Zhitao Gu, Wentao Fang

“…Further exploration of effective adjuvant target therapies is warranted for this patient subgroup.…”
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Lentinan's effect on gut microbiota and inflammatory cytokines in 5-FU-induced mucositis mice by Xiaoxiao Zhang, Liang Wang, Asif Iqbal Khan, Ata Ur Rehman, Kavish Hasnain Khinsar, Yi Xin

“…Abstract Chemotherapeutic therapies for cancer are frequently associated with cytotoxic side effects that can be harmful to human health, including the development of intestinal mucositis (IM). …”
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Efficacy and safety of anemoside B4 in canine pneumonia treatment: a prospective, randomized controlled trial by Jinzhao Ji, Jinzhao Ji, Xiaoqing Ding, Xiaoqing Ding, Chuanli Liu, Chuanli Liu, Lingling Dai, Lingling Dai, Junting Yu, Junting Yu, Linghao Li, Linghao Li, Shaobing Wan, Shaobing Wan, Yangyang Song, Junqing Zhao, Zhetong Su, Kun Jia, Kun Jia, Shoujun Li, Shoujun Li

“…Current treatment strategies primarily rely on antibiotics and corticosteroids; however, the emergence of antibiotic resistance and potential side effects from prolonged corticosteroid use limit the effectiveness of these therapies in clinical practice. These challenges highlight the urgent need for alternative treatments. …”
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A cell-based model to study mechanisms of endothelial-dependent thrombin generation in response to inflammation and its modulation by hydroxychloroquine by Deepa J. Arachchillage, Golzar Mobayen, Mike Laffan, Anna M. Randi, Josefin Ahnström, Charis Pericleous

“…Conclusion: We provide detailed optimization of a robust in vitro model to assess the induction of an inflammation-driven endothelial prothrombotic phenotype that is also sensitive to immunomodulatory therapies, providing a tool for investigating mechanisms of disease and new drugs.…”
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The Impacts of Breakthrough Drug Classes on Total Healthcare Expenditures by Zeynal Karaca, Steven N. Wiggins

“…**Background:** Pharmaceutical firms spend billions of dollars developing new therapies, which are often sold at a substantial premium over older therapies. …”
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Assessing the effects of therapeutic combinations on SARS-CoV-2 infected patient outcomes: A big data approach. by Hamidreza Moradi, H Timothy Bunnell, Bradley S Price, Maryam Khodaverdi, Michael T Vest, James Z Porterfield, Alfred J Anzalone, Susan L Santangelo, Wesley Kimble, Jeremy Harper, William B Hillegass, Sally L Hodder, National COVID Cohort Collaborative (N3C) Consortium

“…<h4>Background</h4>The COVID-19 pandemic has demonstrated the need for efficient and comprehensive, simultaneous assessment of multiple combined novel therapies for viral infection across the range of illness severity. …”
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Preparedness of European pediatric oncologists to integrate AI in the clinical routine by Alberto E. Tozzi, Diana Ferro, Ileana Croci, Francesco Fabozzi, Angela Mastronuzzi

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The Role of Immersive Experience in Anxiety Reduction: Evidence from Virtual Reality Sessions by Dominika Wilczyńska, Tamara Walczak-Kozłowska, David Alarcón, María José Arenilla, Jose Carlos Jaenes, Marcelina Hejła, Mariusz Lipowski, Joanna Nestorowicz, Henryk Olszewski

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Transcriptional and Posttranscriptional Regulations of the HLA-G Gene by Erick C. Castelli, Luciana C. Veiga-Castelli, Layale Yaghi, Philippe Moreau, Eduardo A. Donadi

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Human Immune System Increases Breast Cancer-Induced Osteoblastic Bone Growth in a Humanized Mouse Model without Affecting Normal Bone by Tiina E. Kähkönen, Mari I. Suominen, Jenni H. E. Mäki-Jouppila, Jussi M. Halleen, Azusa Tanaka, Michael Seiler, Jenni Bernoulli

“…Bone metastases are prevalent in many common cancers such as breast, prostate, and lung cancers, and novel therapies for treating bone metastases are needed. …”
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Antiviral Drugs and Vaccines for Omicron Variant: A Focused Review by Nidhi Garg, Ananya Sree Kunamneni, Pankaj Garg, Sandeep Sharma, Divakar Sharma, Adinarayana Kunamneni

“…There are neither clinical trials comparing the efficacy of these 4 therapies with each other nor any data on a combination of two or more therapies. …”
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The Role of HLA-Class Ib Molecules in Immune-Related Diseases, Tumors, and Infections by Fabio Morandi, Enrico Fainardi, Roberta Rizzo, Nathalie Rouas-Freiss

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Fasting for male fertility—a mixed methods study by Katharina T. May, Jocelyn Behling, Katharina Sochiera-Plegniere, Katharina Batschari, Christian S. Kessler, Christian S. Kessler, Christian S. Kessler, Andreas Michalsen, Andreas Michalsen, Farid I. Kandil, Sarah B. Blakeslee, Michael Jeitler, Michael Jeitler, Michael Jeitler, Wiebke Stritter, Daniela A. Koppold, Daniela A. Koppold, Daniela A. Koppold

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Novel Use of an Orbital Atherectomy Device for In-Stent Restenosis: Lessons Learned by K. Shaikh, S. Kelly, M. Gedela, V. Kumar, A. Stys, T. Stys

“…Given limitations in current evidence and therapies, managing ISR can be a technical and cognitive challenge. …”
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HERVs Endophenotype in Autism Spectrum Disorder: Human Endogenous Retroviruses, Specific Immunoreactivity, and Disease Association in Different Family Members by Marco Bo, Alessandra Carta, Chiara Cipriani, Vanna Cavassa, Elena Rita Simula, Nguyen Thi Huyen, Giang Thi Hang Phan, Marta Noli, Claudia Matteucci, Stefano Sotgiu, Emanuela Balestrieri, Leonardo Antonio Sechi

“…Therefore, we propose that investigating their fundamental properties could not only improve existing therapies but also pave the way for new therapeutic strategies.…”
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