Cutaneous Anthrax: What is the Hallmark? by Dhani Redhono Harioputro, Arie Kusumawardani, Iin Novita, Evi Nurhayatun, Rahajeng N Tunjungputri, Erni Juwita Nelwan

“…Prompt and appropriate management largely determines the success of therapy.…”
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Translation and Validation of the Sinhalese Version of the Brief Medication Questionnaire in Patients with Diabetes Mellitus by P. Ranasinghe, R. Jayawardena, P. Katulanda, G. R. Constantine, V. Ramanayake, P. Galappatthy

“…Adherence to long-term therapy for diabetes remains low. Accurately measuring adherence is the primary step in improving adherence. …”
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Vasoreactive testing prevalence and characteristics in patients with idiopathic pulmonary arterial hypertension by Goncharova Natalia, Kirill Lapshin, Aelita Berezina, Irina Zlobina, Anton Ryzhkov, Zhaneta Matakaeva, Elizaveta Andreeva, Olga Moiseeva

“…Positive VRT (VRT+) is an indication for calcium channel blockers therapy. Long-term vasoresponders demonstrate sustained low-risk status and the highest survival among all PH subtypes. …”
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Evaluation of the Clinical Efficacy of Prednisolone in the Treatment of Inflammatory Bowel Diseases with Different Dosage Methods by O. P. Alekseeva, S. V. Krishtopenko, A. A. Alekseeva

“…When two graphs in mg and mg / kg of weight were superimposed, it is shown that when an initial dose of 40 mg is prescribed without taking into account the patient's weight, the effect of therapy will be 25 % lower. Prescribing a dose of 60 mg per day without weight will be optimal for patients with a body weight of 85-90 kg. …”
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Physical parameters and biological factors affect the abscopal effect of combining radiotherapy with immunotherapy: an update on preclinical works by Wangcai Ren, Jialing Wen, Gang Guo, Gang Guo, Wenchao Gu, Shenke Zhang, Shenke Zhang, Chang Liu, Chang Liu, Kensuke Osada, Takashi Shimokawa, Qiaojuan Wang, Qiaojuan Wang, Yue Wang, Yue Wang, Xuanzhang Tu, Chen Li, Li Sui, Liqiu Ma, Liqiu Ma, Liqiu Ma

“…In the process of radiotherapy for cancer patients, there is an extremely low probability phenomenon that the distal tumor/metastasis away from the irradiation field undergoes regression after localized radiation therapy, which is called the abscopal effect. Enhancing the incidence of this phenomenon possesses profound significance for the investigation of metastatic cancer treatment. …”
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A conceptual model for advanced/metastatic gastric or gastroesophageal junction cancer: a review of qualitative studies and results from patient interviews by France Ginchereau Sowell, Thom de Milliano, Keri J. S. Brady, Ginamarie Foglia, Medha Sasane, Samira Bensfia, Matthew Reaney

“…Symptoms were mostly attributed to systemic treatments (chemotherapy, immunotherapy and targeted therapy), followed by surgery. Thirty-one impacts emerged from the interviews, the most common being emotional disturbances, impacts on daily activities and families, and requiring assistance from caregivers. …”
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Effect of whole-body vibration combined with an exercise program in females with chondromalacia: A randomized controlled trial by Anwar Abdelgayed Ebid, Ali A. Elmonsif Thabet, Kadrya H Battecha, Abeer R Ibrahim, Hayam Mahmoud, Mohamed Mohamed Ibrahim Salem, Revan Salem Alammari, Farah Obaid Almuqati, Ghada Jameel Thiga, Maria Ahmad Alsaedi, Leen Khalid Bahamdain

“…The observed disparities between the WBV training group and the EX-group underscore the efficacy of WBV as a potent physical therapy intervention for the rehabilitation of CMP patients, particularly in enhancing strength gains and decreasing pain. …”
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Risdiplam utilization, adherence, and associated health care costs for patients with spinal muscular atrophy: a United States retrospective claims database analysis by Anish Patel, Walter Toro, Min Yang, Wei Song, Raj Desai, Mingchen Ye, Nadia Tabatabaeepour, Omar Dabbous

“…Risdiplam, a daily oral therapy, was approved in the United States for the treatment of SMA. …”
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Azithromycin in the Management of Upper Respiratory Tract Infections (URTIs): Indian Real-Life Experience by Dominic M, Srivastava R, Shah K, Naik SM, Rout K, Ray B, Patil D, Rana D, Swami OC

“…With 5 days of Azithromycin therapy, significant reduction in proportion of patients reporting URTI symptoms and signs was noted. …”
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Prognostic significance of pan-immune-inflammation value in hepatocellular carcinoma treated by curative radiofrequency ablation: potential role for individualized adjuvant systemi... by Xuexia Liang, Juyuan Bu, Yanhui Jiang, Shuqin Zhu, Qing Ye, Yun Deng, Wuzhu Lu, Qiaodan Liu

“…Clinical benefits of adjuvant anti-angiogenesis therapy plus immune checkpoint inhibitor (AA-ICI) following RFA was assessed in low- and high-risk groups.Results The cutoff point of PIV was 120. …”
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The Impact of Effective Vaccination on Clinical and Radiological Involvement in COVID-19 Patients by Coskun DOGAN, Deniz BILICI, Burcu ARPINAR YIGITBAS, Omer ZENGIN, Orhan ZOR, Oguzhan AKMAN, Ilyas KOCABAG, Gonul Seven YALCIN, Esra ERTAN YAZAR

“…The number of patients who received high-dose glucocorticoid therapy in the unvaccinated group was higher (28 cases vs. 11 cases; p<0.001). …”
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Alterations in Adipose Tissue and Adipokines in Heterozygous APE1/Ref-1 Deficient Mice by Eun-Ok Lee, Hao Jin, Sungmin Kim, Hee Kyoung Joo, Yu Ran Lee, Soo Yeon An, Shuyu Piao, Kwon Ho Lee, Byeong Hwa Jeon

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Exploring therapeutic mechanisms of Chuan Huang Fang-II in the treatment of acute kidney injury on chronic kidney disease patients from the perspective of lipidomics by Ling Chen, Qian Wang, Tonglu Li, Lejia Li, Chen Wang, Bing Xu, Xuezhong Gong

“…Both groups received RG therapy, with RG + CHF group additionally receiving CHF-II treatment over a duration of two weeks. …”
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Modulation of glymphatic system by visual circuit activation alleviates memory impairment and apathy in a mouse model of Alzheimer’s disease by Wen Wu, Yubai Zhao, Xin Cheng, Xiaoru Xie, Yixiu Zeng, Quan Tao, Yishuai Yang, Chuan Xiao, Zhan Zhang, Jiahui Pang, Jian Jin, Hongbo He, Yangyang Lin, Boxing Li, Junxian Ma, Xiaojing Ye, Wei-Jye Lin

“…These findings offer functional evidence on the therapeutic effects of 40 hertz blue light in Aβ-related pathologies and suggest its potential as a supplementary strategy to augment the efficacy of antibody-based therapy.…”
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Lactococcus lactis D4 Decreases NF-κB and α-SMA in Rat Models of Obstructive Jaundice by Avit Suchitra, Alvarino Alvarino, Eryati Darwin, Harnavi Harun, Muhammad Iqbal Rivai, Ade Sukma

“…This indicates that LLD4 might be potential as an adjunct therapy for reducing morbidity in obstructive jaundice cases. …”
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Time series analysis combined with transcriptome sequencing to explore characteristic genes and potential molecular mechanisms associated with ultrasound-guided microwave ablation... by Qian Zhang, Guangfei Yang, Ruijiao Chang, Fuxia Wang, Tao Han, Jin Tian, Wen Wang

“…Two immune checkpoints (CD96 and TIGIT) and six inflammatory factors played key roles in US-guided MWA for glioma. ceRNA regulatory networks revealed that miR-625-5p, miR-625-3p, miR-31-5p and miR-671-5p were associated with target genes. qRT-PCR indicated both IL32, VCAM1, and NFKB1 were potential markers under US-guided MWA-related time series analysis.Conclusion The use of US-guided MWA might be a practical method for influencing the function of target genes, regulating time frames to decrease inflammation, and stimulating immune responses in glioma therapy.…”
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Identification and validation of a prognostic risk model based on radiosensitivity-related genes in nasopharyngeal carcinoma by Yi Li, Xinyi Hong, Wenqian Xu, Jinhong Guo, Yongyuan Su, Haolan Li, Yingjie Xie, Xing Chen, Xiong Zheng, Sufang Qiu

“…Background: Despite advancements with intensity-modulated radiation therapy (IMRT), about 10 % of nasopharyngeal carcinoma (NPC) patients remain resistant to radiotherapy, leading to recurrence and poor prognosis. …”
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CYSTIC DEGENERATION OF THE DUODENUM ASSOCIATED WITH CHRONIC PANCREATITIS by A. G. Kriger, A. V. Smirnov, S. V. Berelavichus, D. S. Gorin, N. N. Vetsheva, Ja. I. Nerestjuk, D. V. Kalinin, A. V. Glotov

“…Treatment of patients with CP and DD should be started with conservative therapy. Surgery is indicated for persistent abdominal pain and presence of CP complications. …”
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Ellagic acid ameliorates cisplatin-induced acute kidney injury by regulating inflammation and SIRT6/TNF-α signaling by Yuqi Gao, Kezheng Peng, Yida Wang, Yannan Guo, Chenye Zeng, Rui Hua, Qingfei Liu, Xue Li, Ying Qiu, Zhao Wang

“…For this reason, finding novel targeted therapies to attenuate the nephrotoxicity of cisplatin should be pretty significant. …”
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Tumor Microenvironment Responsive Key Nanomicelles for Effective Against Invasion and Metastasis in Ovarian Cancer Using Mice Model by Liu Y, Kong L, Yu Y, Zang J, Zhang L, Guo RB, Li ST, Cheng L, Li XT, Chen YQ

“…These findings provided a new direction for further exploration of tumor-targeted therapy.Keywords: nano-drug delivery system, tumor microenvironment, docetaxel, triptolide, epithelial mesenchymal transition, angiogenesis…”
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