Severe reversible cardiomyopathy associated with adrenal crisis caused by isolated adrenocorticotropin deficiency: a case report by Li Wang, Fangfang Bu, Lanjie He, Guihua Yao, Guihua Yao

“…In such a case, conventional guideline directed medical therapy (GDMT) for heart failure was not considered suitable because of the underlying hypotension, hypoglycemia, and hyponatremia. …”
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Systemic immune-inflammation index: Unveiling the diagnostic potential in ulcerative colitis through a comprehensive systematic review and meta-analysis by Anas Elgenidy, Omar Alomari, Tasbih Emad, Sara K. Kamal, Islam E. Al Ghanam, Aya Sherif, Mohammed Al-mahdi Al-kurdi, Abdallah A. Helal, Yusof Mohamed Omar, Mohamed Rafiek Ramadan

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Inhibition of miR-182-5p Targets FGF9 to Alleviate Osteoarthritis by Yang Sun, Sanmao Su, Mengjun Li, Ang Deng

“…The aim of this study was to identify the molecular targets of OA therapy, focusing on the expression and biological functions of miR-182-5p and its target genes in OA. …”
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The use of methylene blue in adult patients with septic shock: a systematic review and meta-analysis by Ka Ting Ng, Pei En Kwok, Wei En Lim, Wan Yi Teoh, Mohd Shahnaz Hasan, Mohd Fitry Zainal Abidin

“…Recent studies have advocated the use of methylene blue as a rescue therapy for patients with septic shock. The primary aim was to investigate the effect of methylene blue on the mean arterial pressure among adult patients with septic shock. …”
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Evaluating the Effect of Ramadan Fasting on Muslim Patients with Diabetes in relation to Use of Medication and Lifestyle Patterns: A Prospective Study by Melanie Yee Lee Siaw, Daniel Ek Kwang Chew, Rinkoo Dalan, Shaikh Abdul Kader Kamaldeen Abdul Shakoor, Noorani Othman, Chor Hui Choo, Nur Hidayah Shamsuri, Siti Nurhana Abdul Karim, Sui Yung Chan, Joyce Yu-Chia Lee

“…Those who were hospitalized for diabetic ketoacidosis or severe hypoglycemia a month prior to Ramadan or were given short-term corticosteroid therapy were excluded. The patients’ responses and clinical outcomes from the clinic database were collected before, during, and after Ramadan. …”
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Reductions in Muscle Strength and Range of Motion Cause Locomotion Disability via Locomotion-Related Functional Limitation in Japanese Older Adults: A Cross-Sectional Study by Hungu Jung, Shigeharu Tanaka, Yuji Iwamoto, Takashi Kawano, Masahiro Yamasaki, Ryo Tanaka

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Early, Noninvasive Clinical Indicators of Kidney Prognosis in Primary Nephrotic Syndrome: A Retrospective Exploratory Study by Keiji Fujimoto, Takatoshi Haraguchi, Sho Kumano, Keita Yamazaki, Nobuhiko Miyatake, Kanae Nomura, Kiyotaka Mukai, Kazuaki Okino, Norifumi Hayashi, Hiroki Adachi, Hitoshi Yokoyama, Yasuo Iida, Kengo Furuichi

“…Univariate Cox proportional hazards regression analysis identified clinical parameters in the 2-month period after initiating immunosuppressive therapy (IST); it predicted 40% reduction in the estimated glomerular filtration rate (eGFR) in 36 patients with primary NS. …”
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Synchrotron X-ray imaging study on the mechanism of solids transfer to bitumen froth during oil sands flotation 1: True flotation by Hanyu Zhang, Liuyin Xia, Ning Zhu, Sergey Gasilov, Iris He, Xiaofan Ding

“…The collected bitumen froth was immediately characterized using synchrotron-based X-ray imaging by a monochromatic X-ray with photon energy of 60 keV provided by 05ID-2 beamline of the BioMedical Imaging and Therapy (BMIT) facility at the Canadian Light Source (CLS). …”
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Relationship Between Physical Activity Level and Primary Care Costs in Older Diabetic Patients From a Middle-Size Brazilian City: An Eight-Year Follow-Up Study by Kelly Akemi Kikuti Koyama, Monique Yndawe Castanho Araujo, Luana Carolina de Morais, Italo Ribeiro Lemes, Rômulo Araújo Fernandes, Bruna Camilo Turi-Lynch, Flávia Mori Sarti, Thais Cristina Delacosta, Henrique Luiz Monteiro, Jamile Sanches Codogno

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Low-Intensity Pulsed Ultrasound Modulates RhoA/ROCK Signaling of Rat Mandibular Bone Marrow Mesenchymal Stem Cells to Rescue Their Damaged Cytoskeletal Organization and Cell Biolog... by Rong Zhang, Zhaoling Wang, Guoxiong Zhu, Gaoyi Wu, Qingyuan Guo, Hongchen Liu, Lei Chen

“…Osteoradionecrosis of the jaw (ORNJ) is an infrequent yet potentially devastating complication of head and neck radiation therapy. Low-intensity pulsed ultrasound (LIPUS) has been widely accepted as a promising method for the successful management of ORNJ, but the mechanism remains unclear. …”
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Correlation of serum tumor necrosis factor-α, interleukin-4 and soluble interleukin-2 receptor levels with radiologic and clinical manifestations in active pulmonary tuberculosis by Levent Kart, Hakan Buyukoglan, Ishak O. Tekin, Remzi Altin, Zuhal Senturk, Inci Gulmez, Ramazan Demir, Mustafa Ozesmi

“…We further evaluated whether the levels of TNF-α, IL-4 and soluble IL-2R are related with each other, and also evaluated the levels of TNF-α, IL-4 and sIL-2R after anti-tuberculosis therapy and relation with radiologic scores. Forty-three inpatients with active pulmonary tuberculosis and 19 healthy controls participated in the study. …”
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Enhancing patient engagement: the influence of an in-consult patient decision aid on shared decision-making for lung tumour radiation – protocol for the randomised trial ‘SDM Lung... by Karina Dahl Steffensen, Signe Timm, Torben Frøstrup Hansen, Thomas Leth Fink, Charlotte Kristiansen, Torben Schjødt Hansen, Rune Slot Thing

“…One way of increasing patient engagement is by using shared decision-making (SDM), which is a joint effort of clinicians and patients making decisions together.When planning stereotactic body radiation therapy (SBRT) for a lung tumour located close to the thoracic wall, there are conflicting interests between (1) delivering the highest possible dose to obtain local tumour control and (2) reducing the dose to the thoracic wall to decrease the risk of chest wall pain and rib fractures following treatment. …”
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The effect of an additional pre-extubational loading dose of caffeine citrate on mechanically ventilated preterm infants (NEOKOFF trial): Study protocol for a multicenter randomize... by Kinga Kovács, Rita Nagy, Lilla Andréka, Brigitta Teutsch, Miklós Szabó, Péter Varga, Péter Hegyi, Péter Hársfalvi, Nándor Ács, Ágnes Harmath, Csaba Nádor, Ákos Gasparics

“…Numerous studies have been conducted on the assessment of extubation suitability, the optimal choice of respiratory support around extubation, and the effectiveness of medical interventions. Since the Caffeine Therapy for Apnea of Prematurity (CAP) trial, caffeine has become one of the essential drugs at NICUs. …”
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Evaluation of morphological changes and level of light scattering of the cornea in glaucoma patients by confocal corneal microscopy by G.B. Egorova, V.V. Averich

“…<br> <br> Scientific Research Institute of Eye Diseases, Moscow<br> <br> <b>Aim</b>: to assess morphological changes and the level of light scattering of the cornea in glaucoma patients with noncompensated IOP without using antihypertensive drugs, with medically compensated IOP and with tear-replacement therapy in combination with antiglaucoma drugs.<br> <b>Patients and methods:</b> the first group (20 patients) was examined to determine the normal level of light scattering, the second group (22 patients) had uncompensated IOP, the third group (24 patients) had medically compensated IOP. …”
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Efficacy of PD-1/PD-L1 Inhibitors versus Chemotherapy in Lung Cancer with Brain Metastases: A Systematic Review and Meta-Analysis by Xiaojun Yang, Yihong Zeng, Qinquan Tan, Zhihua Huang, Jun Jia, Guanming Jiang

“…Subgroups analysis of treatment line showed that no advantage for OS with ICIs as first-line or subsequent-line therapy, whereas ICIs as first-line (HR=0.63, 95%CI=0.53–0.74) and second-line (HR=0.62, 95%CI=0.62–0.96) benefitted PFS. …”
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Combined Liver Stiffness and Α-fetoprotein Further beyond the Sustained Virologic Response Visit as Predictors of Long-Term Liver-Related Events in Patients with Chronic Hepatitis... by Sheng-Hung Chen, Hsueh-Chou Lai, Wen-Pang Su, Jung-Ta Kao, Po-Heng Chuang, Wei-Fan Hsu, Hung-Wei Wang, Tsung-Lin Hsieh, Hung-Yao Chen, Cheng-Yuan Peng

“…Of the entire eligible cohort (n = 520) of CHC patients with SVR to antiviral therapy, 28 (5.4%) patients developed post-SVR LREs over a median follow-up period of 6.1 years (interquartile range = 3.5–8.7). …”
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Arthroscopic lateral collateral ligament imbrication for the treatment of posterolateral rotatory elbow instability by Christos Koukos, MD, PhD, Nikolaos Platon Sachinis, MD, PhD, Konstantinos Sidiropoulos, MD, Michael Kotsapas, MD, Kerem Bilsel, MD, PhD, Fredy Montoya, MD, PhD

“…Methods: Forty-three patients with stage 1 or 2 PLRI, unresponsive to conservative therapy, were included. Diagnoses were based on chronic post-traumatic pain (11 patients), chronic atraumatic lateral elbow pain (20), and previous open tennis elbow surgery (12). …”
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THE OCCURRENCE OF CONTRACTURE AND THE SEVERITY OF BURN INJURIES AMONG BURN PATIENTS TREATED AT DR. SOETOMO GENERAL ACADEMIC HOSPITAL, SURABAYA, INDONESIA (2020-2022) by Gifta Marshanda Qanitah Hamiseno, Iswinarno Doso Saputro, Diah Mira Indramaya, Lobredia Zarasade

“…Proper management through medicine, surgery, and therapy is crucial for helping these patients. Research at Dr. …”
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Epigenetics of suicidal behavior by R. N. Mustafin, A. V. Kazantseva, R. F. Enikeeva, Yu. D. Davydova, S. B. Malykh, V. V. Viktorov, E. K. Khusnutdinova

“…The role of histone modifications in distinct genes (Cx30, Cx43, TrkB.T1) and the expression of specific long noncoding RNAs and microRNAs in the development of suicidal behavior, which is promising for the development of diagnostic algorithms and target therapy, is discussed.…”
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X-Linked Adrenal Hypoplasia Congenita in a Boy due to a Novel Deletion of the Entire NR0B1 (DAX1) and MAGEB1–4 Genes by Aleksandra Rojek, Maciej R. Krawczynski, Aleksander Jamsheer, Anna Sowinska-Seidler, Barbara Iwaniszewska, Ewa Malunowicz, Marek Niedziela

“…Primary adrenal insufficiency was confirmed with low serum cortisol levels and high plasma ACTH levels. Hydrocortisone therapy combined with saline and glucose infusions was started immediately after blood collection. …”
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