Pericardial mesothelioma mimicking mediastinal lymphoma and systemic rheumatic disease: a case report by Grzegorz Hirnle, Michał Kapałka, Michał Krawiec, Tomasz Hrapkowicz

“…The patient was diagnosed with systemic lupus erythematosus (SLE) and initiated on chronic steroid therapy. As heart failure progressed, the patient was admitted to the cardiology department. …”
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Blood Genomics Identifies Three Subtypes of Systemic Lupus Erythematosus: “IFN-High,” “NE-High,” and “Mixed” by Mintian Cui, Taotao Li, Xinwei Yan, Chao Wang, Qi Shen, Hongbiao Ren, Liangshuang Li, Ruijie Zhang

“…Our research results indicated that identifying the molecular mechanism associated with different SLE subtypes would benefit the molecular diagnosis and stratified therapy. Moreover, repositioning of IFN-K based on subtypes also revealed an improved therapeutic effect, providing a new direction for disease treatment and drug development.…”
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Critical pathomechanisms of NSAID-exacerbated respiratory disease (N-ERD) clarified by treatment with omalizumab, an anti-IgE antibody by Hiroaki Hayashi, Makoto Ishii, Yoshinori Hasegawa, Masami Taniguchi

“…Based on the preliminary study, we demonstrated that omalizumab induced tolerance to aspirin in N-ERD patients 3 months after therapy initiation and suppressed activation of mast cells during 24 h of initiation in a randomized manner. …”
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Current surgical treatment options for ocular complications of Stevens-Johnson and Lyell's syndromes by V.F. Chernysh, N.N. Haritonova, A.N. Kulikov, P.A. Kacherovich, A.A. Kol'bin

“…Timely treatment of Stevens-Johnson and Lyell's syndromes comprising systemic and topical conservative therapy in combination with surgical procedures during the acute stage plays an important role for the prediction of severe long-term ocular complications. …”
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Research investigating patient and carer psychoeducation needs regarding post-stroke cognition: a scoping review by Nele Demeyere, Georgina Hobden, Faye Tabone

“…Qualitative analysis suggested participants wanted psychoeducation about cognitive impairment, including recovery expectations, treatment/therapy options and signposting to services/resources available. …”
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A novel anti-epileptogenesis strategy of temporal lobe epilepsy based on nitric oxide donor by Xian-Hui Zhu, Ya-Ping Zhou, Qiao Zhang, Ming-Yi Zhu, Xiao-Wei Song, Jun Li, Jiang Chen, Yun Shi, Kang-Jian Sun, Yong-Jie Zhang, Jing Zhang, Tian Xia, Bao-Sheng Huang, Fan Meng, Qi-Gang Zhou

“…Therefore, we concluded that NO donor therapy may be a novel anti-epileptogenesis strategy, different from existing antiseizure medications (ASMs), for curing TLE.…”
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Nanoparticle accumulation and penetration in 3D tumor models: the effect of size, shape, and surface charge by Pierre Cybulski, Maria Bravo, Maria Bravo, Jim Jui-Kai Chen, Indra Van Zundert, Sandra Krzyzowska, Farsai Taemaitree, Hiroshi Uji-i, Hiroshi Uji-i, Hiroshi Uji-i, Johan Hofkens, Johan Hofkens, Susana Rocha, Beatrice Fortuni

“…Preclinical studies have demonstrated that nanoparticles (NPs) hold significant potential for advancing cancer therapy by enhancing therapeutic efficacy while reducing side effects. …”
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The pain ratio before and after the application of physiotherapy for dysfunction of temporomandibular joint by Lejla Hadžić, Peter Heidemann, Samir Bojičić, Namik Trtak, Eldad Kaljić, Amra Mačak Hadžiomerović

“… Introduction: Physiotherapy, a non-invasive method of conservative treatment, that includes manual therapy, exercises and physical procedures, is used in the treatment of temporomandibular dysfunction and polyarticular laxity. …”
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Cyclin-dependent kinase 4 and 6 inhibitors (CDK4/6i): Mechanisms of resistance and where to find them by L. Foffano, L. Cucciniello, E. Nicolò, I. Migliaccio, C. Noto, C. Reduzzi, L. Malorni, M. Cristofanilli, L. Gerratana, F. Puglisi

“…CDK4/6 inhibitors (CDK4/6i) have significantly impacted on the treatment of HR + HER2 negative (HER2-) metastatic breast cancer (BC) when combined with endocrine therapy. Nonetheless, despite significant research efforts, the mechanisms of de novo and acquired resistance to CDK4/6i have not yet been fully elucidated, highlighting the need for a deeper understanding of these process. …”
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Comparison of the Efficacy and Tolerability of Dienogest and Dienogest Plus Ethinylestradiol on Endometriosis Related-Pain by Tolga Karacan, Huseyin Kiyak, Eser Ozyurek, Mevlide San, Engin Oral

“…The intensity of pain symptoms was evaluated before therapy, then after 3 and 6 months of treatment using a 10-point numerical rating scale (0 = no pain and 10 = worst possible pain) (NRS) provided to the patients in advance. …”
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Osteoblast‐Derived ECM1 Promotes Anti‐Androgen Resistance in Bone Metastatic Prostate Cancer by Xinwen Wang, Min Wang, Qijun Lin, Lixin He, Baolin Zhang, Xin Chen, Guanhong Chen, Hong Du, Chuandong Lang, Xinsheng Peng, Yuhu Dai

“…Abstract Acquired resistance to hormonal therapy, particularly enzalutamide (ENZ), remains a significant obstacle in the treatment of advanced bone metastatic prostate cancer. …”
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Worldwide Research Trends on Diabetic Foot Ulcers (2004–2020): Suggestions for Researchers by Pin Deng, Hongshuo Shi, Xuyue Pan, Huan Liang, Shulong Wang, Junde Wu, Wei Zhang, Fasen Huang, Xiaojie Sun, Hanjie Zhu, Zhaojun Chen

“…Studies on osteomyelitis, wound therapy and management, multidisciplinary integration and mechanism of DFUs, and its related diseases are the research fronts that should be closely watched in the future. …”
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Effect of Hot and Cold Chinese Medicine Whirlpool Bath Combined with Motor Control Training on Patients with Shoulder-Hand Syndrome after Stroke by ZHANG Yuming, ZHANG Xiufang, CHEN Jie, LI Ning, ZHANG Xiaolin, ZHANG Ming

“…Both groups received routine rehabilitation training such as physical agent modalities and occupational therapy. The control group received motor control training on the basis of routine rehabilitation training, 40 minutes a time, once a day, five times a week, lasting for four weeks; the observation group received hot and cold Chinese medicine whirlpool bath on the basis of control group, 40 minutes a time, once a day, five times a week, lasting for four weeks. …”
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Guidelines for the Management of Complications of Diabetes in Saudi Arabia Using Delphi Technique for Consensus Among National Experts by Raed Aldahash, Mohammed A. Batais, Ashraf El-Metwally, Saja Alhosan, Mohammed Alharbi, Mohammed Almutairi, Abdulghani Alsaeed, Mohammed Alsofiani, Mohammed AlMehthel, Mohammed Aldubayee, Khaled Aldossari, Sulieman Alshehri

“…They highlight the importance of lifestyle changes and medical therapy. However, due to the ever-changing nature of diabetes, the document must be monitored and updated on a regular basis to ensure its continued relevance and effectiveness.…”
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Functional Constipation in Children: overview and new outcomes by Kamila Stępień, Maria Przygoda, Joanna Śnieżna, Gabriela Trestka, Sabina Adamczyk, Urszula Zelik, Jakub Dziewic, Wojciech Florczak, Wiktoria Domino, Jagienka Włodyka, Karol Dzwonnik

“…Management includes dietary modifications, behavioral interventions, pharmacotherapy, and, in some cases, biofeedback therapy. Long-term outcomes are generally favorable with appropriate treatment, although relapse is common, emphasizing the need for sustained management. …”
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Design and Deployment of a Pediatric Cardiac Arrest Surveillance System by Jordan Michel Duval-Arnould, Heather Marie Newton, Leann McNamara, Branden Michael Engorn, Kareen Jones, Meghan Bernier, Pamela Dodge, Cheryl Salamone, Utpal Bhalala, Justin M. Jeffers, Lilly Engineer, Marie Diener-West, Elizabeth Anne Hunt

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Hospital utilization and telemedicine preferences in patients with late-stage Parkinson’s disease and caregivers by Seo Hyun Hong, Seoyeon Kim, Seungmin Lee, Bora Jin, Jung Hwan Shin, Kyung Ah Woo, Han-Joon Kim

“…Over three-quarters of patients did not receive rehabilitation therapy, mainly due to mobility issues and the lack of nearby facilities. …”
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The Urinary Liver-Type Fatty Acid Binding Protein (L-FABP) in Early Detection and Outcome Prediction of Sepsis-Associated Acute Kidney Injury by Ghi Nguyen Hai, Binh Nguyen Gia, Hoa Do Thanh, Cuong Nguyen Thai, Duc Vu Anh, Anh Duong Duc, Duong Le Xuan Xuan

“…The screening performance characteristics of urinary L-FABP in early detection of AKI within seven days of admission and need for renal replacement therapy (RRT) were calculated and reported. Results: 212 patients with the mean age of 66.5 ± 16.2 (range 18-99) years were included (60.4% male). 54 (25.5%) patients had sepsis, and septic shock was developed in 158 (74.53%) cases. 143 (67.5%) patients were complicated with AKI. …”
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Identification of a Ferroptosis-Related Signature Associated with Prognosis and Immune Infiltration in Adrenocortical Carcinoma by Xi Chen, Lijun Yan, Feng Jiang, Yu Lu, Ni Zeng, Shufang Yang, Xianghua Ma

“…It also brings us new insights into the possible value of targeting ferroptosis during the therapy of ACC.…”
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HMGB1 released from pyroptotic vascular endothelial cells promotes immune disorders in exertional heatstroke by Chaoping Yu, Yang Huang, Jiangang Xie, Chujun Duan, Shanshou Liu, Wei Zhao, Yutong Wang, Ran Zhuang, Junjie Li, Wen Yin

“…Administration of anti-HMGB1 markedly alleviated tissue injury and systemic inflammatory responses after EHS.Conclusions The release of HMGB1 from pyroptotic endothelial cells after EHS promotes pyroptosis of macrophages and systemic inflammatory response, and HMGB1-neutralizing antibody therapy has good application prospects for EHS.…”
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