Small molecules in idiopathic inflammatory myopathies: a systematic review and a multicenter case series about Janus kinase inhibitors and apremilast by Chiara Rizzo, Silvia Grazzini, Edoardo Conticini, Hector Chinoy, Roberto D’Alessandro, Federica Camarda, Luca Cantarini, Bruno Frediani, Giuliana Guggino, Lidia La Barbera

“…If present, muscle and joint involvement demonstrated a good response to therapy, while it was not possible to draw any conclusion about dysphagia. …”
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Synergistic Effects of FGF-18 and TGF-β3 on the Chondrogenesis of Human Adipose-Derived Mesenchymal Stem Cells in the Pellet Culture by Liangjie Huang, Lingxian Yi, Chunli Zhang, Ying He, Liangliang Zhou, Yan Liu, Long Qian, Shuxun Hou, Tujun Weng

“…Cell-based therapy serves as an effective way for cartilage repair. …”
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Toll-Like Receptor Homolog CD180 Expression Is Diminished on Natural Autoantibody-Producing B Cells of Patients with Autoimmune CNS Disorders by Zsófia Hayden, Szabina Erdő-Bonyár, Beáta Bóné, Noémi Balázs, Kornélia Bodó, Zsolt Illes, Timea Berki, Diána Simon

“…Effectiveness of anti-CD20 therapy in neuromyelitis optica spectrum disorder (NMOSD) and multiple sclerosis (MS) strengthens the role of B cells in the pathogenesis. …”
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Effectiveness of acupuncture for equine laminitis: Systematic review and meta-analysis by Faisal Fikri, Agus Purnomo, Salipudin Tasil Maslamama, Muhammad Thohawi Elziyad Purnama

“…Background and Aim: In the past 20 years, acupuncture has been utilized as an alternative therapy for equine laminitis despite a lack of clinical evidence to support its effectiveness. …”
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Short-term outcomes of oropharyngeal administration of colostrum in preterm neonates: a double-blind placebocontrolled randomized trial by Ameneh Lamsehchi, Maryam Shokouhi Solgi, Mohammad Kazem Sabzehei, Behnaz Basiri, Elahe Talebi Ghane, Kiana Kimiaei Asadi, Sina Azadnajafabad

“…Moreover, the mean duration of antibiotic therapy and period to full feeding were significantly shorter in the intervention group. …”
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Cytotoxicity Potentials of Eleven Bangladeshi Medicinal Plants by Amina Khatun, Mahmudur Rahman, Tania Haque, Md. Mahfizur Rahman, Mahfuja Akter, Subarna Akter, Afrin Jhumur

“…Various forms of cancer are rising all over the world, requiring newer therapy. The quest of anticancer drugs both from natural and synthetic sources is the demand of time. …”
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Surgery and Medical Treatment in Microprolactinoma: A Systematic Review and Meta-Analysis by Jianglong Lu, Lin Cai, Zerui Wu, Weiwei Lin, Jiadong Xu, Zhangzhang Zhu, Chengde Wang, Qun Li, Zhipeng Su

“…The aim of this systematic review and meta-analysis was to compare the clinical result of DA treatment with surgery as initial therapy in patients with treatment-naive microprolactinoma. …”
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Exploring voyeurism: a review of research by Krystian Wdowiak, Agnieszka Maciocha, Julia Wąż, Aleksandra Witas, Justyna Drogoń, Edyta Gwóźdź, Adrian Muzyka, Julia Rydzek, Ewa Gardocka

“…Treatment primarily involves cognitive behavioral therapy (CBT), with pharmacological support using SSRIs like fluoxetine and paroxetine, showing effectiveness. …”
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The association between dolutegravir-based antiretrovirals and high blood pressure among adults with HIV in southern Ethiopia: a cross-sectional study by Agete Tadewos Hirigo, Daniel Yilma, Ayalew Astatkie, Zelalem Debebe

“…Background: Dolutegravir (DTG), a novel antiretroviral therapy (ART) for HIV, is increasingly adopted across sub-Saharan Africa. …”
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Gaps in cancer care in a multi-ethnic population in Sarawak, Borneo: A central referral centre study. by Melissa Siaw Han Lim, Pei Jye Voon, Adibah Ali, Fitri Suraya Mohamad, Lin Lin Jong, Lee Ping Chew, Mohamad Adam Bujang, Yolanda Augustin, Yuong Kang Cheng

“…The perceived importance of information provided and level of patient satisfaction were assessed with a 5-point Likert scale in 10 domains (Diagnosis, Surgery, Radiotherapy, Systemic therapy, Clinical trials, Pain management, Treatment monitoring, Psychosocial support, Sexual care and fertility issues, and Financial support). …”
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Exploring the association between statins use or HMG-CoA reductase inhibition and migraine: a systematic review and meta-analysis by Hamdy A. Makhlouf, Amr K. Hassan, Nereen A. Almosilhy, Ahmed S.A. Osman, Shrouk Ramadan, Moaz Elsayed Abouelmagd

“…Conclusions Statins, already well-established for cardiovascular benefits, emerge as a promising dual-purpose therapy for many neurological disorders. The association between the HMGCR gene and increased migraine risk, coupled with the possible efficacy of statins in reducing migraine frequency, may open new avenues for migraine prophylaxis. …”
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Using machine learning models to plan HIV services: Emerging opportunities in design, implementation and evaluation by T Dzinamarira, E Mbunge, I Chingombe, D F Cuadros, E Moyo, I Chitungo, G Murewanhema, B Muchemwa, G Rwibasira, O Mugurungi, G Musuka, H Herrera

“…However, barriers such as lack of engagement, limited availability of early HIV-infection detection tools, high rates of HIV/sexually transmitted infections (STIs), barriers to access antiretroviral therapy, lack of innovative resource optimisation and distribution strategies, and poor prevention services for vulnerable populations still exist and substantially affect the attainment of the UNAIDS 95-95-95 targets. …”
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Development of Speech and Communication in Polish Children with 22q11.2 Deletion Syndrome: A Cross-Sectional Study by Natalia Moćko, Marcin Rudzki, Zuzanna Miodońska, Julia Olesiak, Katarzyna Jochymczyk-Woźniak, Michał Kręcichwost

“…The questionnaire covered the following speech and communication development stages: babbling, using first words, first sentences, verbal and non-verbal communication, speech disfluencies, hearing loss, speech intelligibility, difficulties in interpersonal contact, and participation in speech therapy. The obtained answers underwent statistical analysis to verify relationships between the stages of personal development and selected dysfunctions and disorders. …”
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Immune Activation, Immunosenescence, and Osteoprotegerin as Markers of Endothelial Dysfunction in Subclinical HIV-Associated Atherosclerosis by Alessandra D’Abramo, Maria Antonella Zingaropoli, Alessandra Oliva, Claudia D’Agostino, Samir Al Moghazi, Giulia De Luca, Marco Iannetta, Claudio Maria Mastroianni, Vincenzo Vullo

“…We investigated the relationship between T-cell phenotype, osteoprotegerin, and atherosclerosis evaluated by carotid intima-media thickness (c-IMT) in 94 HIV+ patients on suppressive antiretroviral therapy with Framingham score <10%. As for the control group, 24 HIV-negative subjects were enrolled. c-IMT was assessed by ultrasound. …”
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NCOA4 linked to endothelial cell ferritinophagy and ferroptosis:a key regulator aggravate aortic endothelial inflammation and atherosclerosis by Li Zhu, Zijian Liu, Jiahui Liu, Zhenglong Li, Youli Bao, Xin Sun, Wenchen Zhao, An Zhou, Hongfei Wu

“…Collectively, our results provide evidence of a connection between NCOA4-mediated promotion of AS and suggest that targeting upstream molecules regulating NCOA4 could be a potential therapy for AS.…”
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The Combined Use of Platelet-Rich Plasma Clot Releasate and Allogeneic Human Umbilical Cord Mesenchymal Stem Cells Rescue Glucocorticoid-Induced Osteonecrosis of the Femoral Head by Yanxue Wang, Shuo Luan, Ze Yuan, Shaoling Wang, Shengnuo Fan, Chao Ma, Shaoling Wu

“…The current study provides important information on intra-articular therapy, paving the way for the clinical management of ONFH in the future.…”
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Next generation bioelectronic medicine: making the case for non-invasive closed-loop autonomic neuromodulation by Imanuel Lerman, Yifeng Bu, Rahul Singh, Harold A. Silverman, Anuj Bhardwaj, Alex J. Mann, Alik Widge, Joseph Palin, Christopher Puleo, Hubert Lim

“…Abstract The field of bioelectronic medicine has advanced rapidly from rudimentary electrical therapies to cutting-edge closed-loop systems that integrate real-time physiological monitoring with adaptive neuromodulation. …”
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Assessment of older persons with multimorbidity in Norwegian primary care: a qualitative study of healthcare professionals’ experiences and preferences in fostering continuity of c... by Turid Rimereit Aarønes, Kristin Taraldsen, Linda Aimée Hartford Kvæl

“…Representing nursing, physiotherapy, occupational therapy and social work, all participants were experienced in assessing older home-dwelling patients with multimorbidity. …”
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Magnolol induces cell death through PI3K/Akt‐mediated epigenetic modifications boosting treatment of BRAF‐ and NRAS‐mutant melanoma by Abdullah Al Emran, Brinda Reddy Chinna Chowdary, Farzana Ahmed, Heinz Hammerlindl, Antje Huefner, Nikolas K. Haass, Wolfgang Schuehly, Helmut Schaider

“…Combination of magnolol with targeted therapy or chemotherapy also led to analogous effects on histone marks, which was rescued by Akt pathway activation. …”
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RISK FACTORS OF LIFE QUALITY REDUCTION IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS by Vitalii Dubas

“…The main parameters of the quality of life in the 2 groups were compared, as well as their dependence on clinical manifestations and therapy was studied. Results and Dyscussion. Physical well-being in patients with SLE (29.6±2.97) is significantly lower (p<0.001) than in healthy individuals (55.8±3.31). …”
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